2,108 research outputs found

    Rotor vibration caused by external excitation and rub

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    For turbomachinery with low natural frequencies, considerations have been recently required for rotor vibrations caused by external forces except unbalance one, such as foundation motion, seismic wave, rub and so forth. Such a forced vibration is investigated analytically and experimentally in the present paper. Vibrations in a rotor-bearing system under a harmonic excitation are analyzed by the modal technique in the case of a linear system including gyroscopic effect. For a nonlinear system a new and powerful quasi-modal technique is developed and applied to the vibration caused by rub

    On Two Types of with Absolute Phrases

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    0. The with absolute construction has recently attracted the increasing attention of generative-transformational linguists (e.g., Ishihara (1982), McCawley (1983), etc.) and not a few syntactic and semantic facts of theoretical interest have begun to come to light. ..

    Weak crossover : quantificationality or indefiniteness

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    So-called weak crossover phenomena, which are examplified by (1a-b), have usually been accounted for by attributing the ungrammaticality to the quantifierhood of the relaevant elements, who and everyone; ..

    The Use of Evidence-Based Prevention Guidelines in Ventilator Associated Pneumonia

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    Abstract Background: Ventilator Associated Pneumonia is a hospital acquired condition that affects the lungs while mechanically ventilated. Infections occur when bacteria is introduced into the patients airway, typically when nurses perform routine care on their patients. Ventilator Associated Pneumonia can worsen the condition of patients significantly. Significance: Ventilator Associated Pneumonia is the fourth most common adult healthcare-associated infection in the United States, accounting for nearly 3% (CDC, 2018). Within the ICU, 77% of patients that were mechanically ventilated had at least one ventilator associated condition; 29% of those had at least one infection occur (Bouadma, 2015). Ventilator Associated Pneumonia causes longer admission time as well as a higher mortality rates for thousands of patients a year; the use of multiple simple prevention strategies could reduce the rate of infection. Purpose: The purpose of this project is to introduce the standards of care used in preventing ventilator associated pneumonia, and to discuss the significance of nurse education on the topic. Through article analysis and personal clinical experience, this project will demonstrate the importance in preventing ventilator associated pneumonia and make suggestions to improve nursing practice. I will explore the occurrence of VAP on the ICU unit in which I work, as well as the protocols Wellstar has in place to prevent that occurrence. Article Review: The articles reviewed for this project were all from peer reviewed sources as well as professional organizations. Most information found has been put into practice over the Covid-19 pandemic with more patients requiring ventilation

    Second cancer risk after intensity-modulated and conventional radiotherapy in a small animal model

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    Introduction: Intensity-modulated radiotherapy (IMRT) involves exposure of large volumes of healthy tissue to a low-dose. This is thought to increase the risk of a radiation-induced second cancer (SC) compared to 3D-conformal radiotherapy (3D-CRT). As a consequence, patients with radiotherapy curable diseases such as pediatric and juvenile Hodgkin's Lymphoma (HL) are not treated with IMRT techniques thereby accepting high(er) doses to the heart and breast. The purpose was to test this dogma in cancer-susceptible rats irradiated either with a highly conformal volumetric-modulated arc therapy (VMAT, a rotational IMRT) or a conventional 3D-CRT in form of two opposite anterior-posterior / posterior-anterior (AP/PA) technique. Methods: Heterozygous Tumor protein 53 knockout rats belonging to four treatment groups of n = 15 animals each were irradiated with either 3×5 Gy or 3×8 Gy doses delivered with VMAT or AP/PA to a mediastinal planning target volume (PTV). Two control groups were given anesthesia only (AN, n = 15) or anesthesia with additional cone-beam computed tomography (CBCT) scanning (CBCT, n = 15). Animals were followed up to tumor detection using high-resolution CT. Tumors were scored according to the volume in which they occurred: low dose volume (LDV, receiving lower than 50% of target doses), bordering high dose volume (BHDV, 50% - 90%), high dose volume (HDV, > 90%) or non-irradiated volume (NIRV). Tumor and healthy tissues were characterized by histology. The analysis of loss of heterozygosity (LOH) of Tp53, were performed using Polymerase Chain Reaction (PCR) and sequencing. Tumor development after VMAT vs. AP/PA compared using Fisher’s exact test, Kaplan-Meier analysis, and the Mann-Whitney test (α < 0.05). Results: In 84/90 animals, at least one tumor was detected, while six were lost due to other causes. In AN- and CBCT- control groups, all tumors were found in the body volumes corresponding to the NIRV of irradiated animals. By contrast (p = 0.0001), in the irradiated groups, 17/29 (after 3×5 Gy) and 16/28 (after 3×8 Gy) of all tumors were found in the volumes exposed to doses 0.75 – 24 Gy. The majority (23/33) of these irradiated volume-associated tumors were found inside the HDV, whereas only n = 3 tumors were detected in the BHDV and n = 7 in the LDV (combined 3×5 Gy and 3×8 Gy groups). Notably, no increased tumor induction was observed in the volume irradiated with VMAT compared to AP/PA (14/28 vs. 19/29, p = 0.44). The attained age from birth, for control rat groups and groups treated with 3×5 Gy were similar, while decreased significantly in 3×8 Gy VMAT (p = 0.02) and AP/PA (p = 0.0005) due to earlier tumor appearance compared to controls. A maximum decrease in time to tumor (TTT), from treatment to appearance, compared to AN/CBCT revealed for tumors within the BHDV/HDV after 3×8 Gy treatment (p < 0.0001). All lymphomas and most soft tissue sarcomas were specifically developed in the irradiated volume without regard to radiation doses and techniques. LOH was not significantly specific for tumors in the irradiated volume or for the shortening of the TTT, and no inflammatory background in irradiated rat lungs was observed. Conclusions: The present results do not support the hypothesis that the enlarged low-dose volume generated in highly conformal radiotherapy techniques is associated with a higher SC risk. In contrast, the results show that higher local doses to normal tissue can accelerate the development of radiation-associated lymphoma and sarcoma, regardless of the RT technique used, LOH in tumors, or an inflammatory background in the lungs

    Provincial Regulation of Natural Resource Exploitation

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    natural resources--Canada, natural resources--United State

    Vu: A Databse Computer Language for the Simulation of Events in the City

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    OUR ENVIRONMENTAL ANALYSIS TOOLS PREPARED AND THE APPLICABILITY TO JOINT RESEARCH WITH VIETNAM

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    Joint Research on Environmental Science and Technology for the Eart

    長田秀樹先生を偲ぶ

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