733 research outputs found
Spectral fluctuation characterization of random matrix ensembles through wavelets
A recently developed wavelet based approach is employed to characterize the
scaling behavior of spectral fluctuations of random matrix ensembles, as well
as complex atomic systems. Our study clearly reveals anti-persistent behavior
and supports the Fourier power spectral analysis. It also finds evidence for
multi-fractal nature in the atomic spectra. The multi-resolution and
localization nature of the discrete wavelets ideally characterizes the
fluctuations in these time series, some of which are not stationary.Comment: 7 pages, 2 eps figure
Moving Beyond Noninformative Priors: Why and How to Choose Weakly Informative Priors in Bayesian Analyses
Throughout the last two decades, Bayesian statistical methods have proliferated throughout ecology and evolution. Numerous previous references established both philosophical and computational guidelines for implementing Bayesian methods. However, protocols for incorporating prior information, the defining characteristic of Bayesian philosophy, are nearly nonexistent in the ecological literature. Here, I hope to encourage the use of weakly informative priors in ecology and evolution by providing a ‘consumer\u27s guide’ to weakly informative priors. The first section outlines three reasons why ecologists should abandon noninformative priors: 1) common flat priors are not always noninformative, 2) noninformative priors provide the same result as simpler frequentist methods, and 3) noninformative priors suffer from the same high type I and type M error rates as frequentist methods. The second section provides a guide for implementing informative priors, wherein I detail convenient ‘reference’ prior distributions for common statistical models (i.e. regression, ANOVA, hierarchical models). I then use simulations to visually demonstrate how informative priors influence posterior parameter estimates. With the guidelines provided here, I hope to encourage the use of weakly informative priors for Bayesian analyses in ecology. Ecologists can and should debate the appropriate form of prior information, but should consider weakly informative priors as the new ‘default’ prior for any Bayesian model
Activity and Process Stability of Purified Green Pepper (Capsicum annuum) Pectin Methylesterase
Pectin methylesterase (PME) from green bell peppers (Capsicum annuum) was extracted and purified by affinity chromatography on a CNBr-Sepharose-PMEI column. A single protein peak with pectin methylesterase activity was observed. For the pepper PME, a biochemical characterization in terms of molar mass (MM), isoelectric points (pI), and kinetic parameters for activity and thermostability was performed. The optimum pH for PME activity at 22 °C was 7.5, and its optimum temperature at neutral pH was between 52.5 and 55.0 °C. The purified pepper PME required the presence of 0.13 M NaCl for optimum activity. Isothermal inactivation of purified pepper PME in 20 mM Tris buffer (pH 7.5) could be described by a fractional conversion model for lower temperatures (55?57 °C) and a biphasic model for higher temperatures (58?70 °C). The enzyme showed a stable behavior toward high-pressure/temperature treatments. Keywords: Capsicum annuum; pepper; pectin methylesterase; purification; characterization; thermal and high-pressure stabilit
A new CP violating observable for the LHC
We study a new type of CP violating observable that arises in three body
decays that are dominated by an intermediate resonance. If two interfering
diagrams exist with different orderings of final state particles, the required
CP-even phase arises due to the different virtualities of the resonance in each
of the two diagrams. This method can be an important tool for accessing new CP
phases at the LHC and future colliders.Comment: 22 pages, v2: discussion of charged particle decays and a few
references added v3: typos corrected, matches published versio
Towards precision medicine for hypertension: a review of genomic, epigenomic, and microbiomic effects on blood pressure in experimental rat models and humans
Compelling evidence for the inherited nature of essential hypertension has led to extensive research in rats and humans. Rats have served as the primary model for research on the genetics of hypertension resulting in identification of genomic regions that are causally associated with hypertension. In more recent times, genome-wide studies in humans have also begun to improve our understanding of the inheritance of polygenic forms of hypertension. Based on the chronological progression of research into the genetics of hypertension as the "structural backbone," this review catalogs and discusses the rat and human genetic elements mapped and implicated in blood pressure regulation. Furthermore, the knowledge gained from these genetic studies that provide evidence to suggest that much of the genetic influence on hypertension residing within noncoding elements of our DNA and operating through pervasive epistasis or gene-gene interactions is highlighted. Lastly, perspectives on current thinking that the more complex "triad" of the genome, epigenome, and the microbiome operating to influence the inheritance of hypertension, is documented. Overall, the collective knowledge gained from rats and humans is disappointing in the sense that major hypertension-causing genes as targets for clinical management of essential hypertension may not be a clinical reality. On the other hand, the realization that the polygenic nature of hypertension prevents any single locus from being a relevant clinical target for all humans directs future studies on the genetics of hypertension towards an individualized genomic approach
Momentum asymmetries as CP violating observables
Three body decays can exhibit CP violation that arises from interfering
diagrams with different orderings of the final state particles. We construct
several momentum asymmetry observables that are accessible in a hadron collider
environment where some of the final state particles are not reconstructed and
not all the kinematic information can be extracted. We discuss the
complications that arise from the different possible production mechanisms of
the decaying particle. Examples involving heavy neutralino decays in
supersymmetric theories and heavy Majorana neutrino decays in Type-I seesaw
models are examined.Comment: 20 pages, 9 figures. Clarifying comments and one reference added,
matches published versio
Measurement of the Partila Width and Form Factor Parameters
We have studied the decay , where . From a fit to the differential decay rate we measure the
rate normalization and form factor slope
, and, using measured values of , find . The resulting branching
fractions are and .
The form factor parameters are in agreement with those measured in decays, as predicted by heavy quark effective theory.Comment: 11 pages, postscript file also available through
http://w4.lns.cornell.edu/public/CLN
A Non-parametric Approach to the D+ to K*0bar mu+ nu Form Factors
Using a large sample of D+ -> K- pi+ mu+ nu decays collected by the FOCUS
photoproduction experiment at Fermilab, we present the first measurements of
the helicity basis form factors free from the assumption of spectroscopic pole
dominance. We also present the first information on the form factor that
controls the s-wave interference discussed in a previous paper by the FOCUS
collaboration. We find reasonable agreement with the usual assumption of
spectroscopic pole dominance and measured form factor ratios.Comment: 14 pages, 5 figures, and 2 tables. We updated the previous version by
changing some words, removing one plot, and adding two tables. These changes
are mostly stylisti
New Measurements of the D+ to K* mu nu Form Factor Ratios
Using a large sample of D+ to K- pi+ mu+ nu decays collected by the FOCUS
photoproduction experiment at Fermilab, we present new measurements of two
semileptonic form factor ratios: rv and r2. We find rv = 1.504 \pm 0.057 \pm
0.039 and r2 = 0.875 \pm 0.049 \pm 0.064. Our form factor results include the
effects of the s-wave interference discussed in a previous paper.Comment: 12 pages, 5 figure
Hadronic Mass Spectrum Analysis of D+ into K- pi+ mu+ nu Decay and Measurement of the K*(892)^0 Mass and Width
We present a Kpi mass spectrum analysis of the four-body semileptonic charm
decay D+ into K- pi+ mu+ nu in the range of 0.65 GeV < mKpi < 1.5 GeV. We
observe a non-resonant contribution of 5.30 +- 0.74 +0.99 -0.51 % with respect
to the total D+ into K- pi+ mu+ nu decay. For the K*(892)^0 resonance, we
obtain a mass of 895.41 +- 0.32 +0.35 -0.36 MeV, a width of 47.79 +- 0.86 +1.3
-1.1 MeV, and a Blatt-Weisskopf damping factor parameter of 3.96 +- 0.54 +0.72
-0.90 GeV^(-1). We also report 90 % CL upper limits of 4 % and 0.64 % for the
branching ratios of D+ into K*(1680)^0 mu+ nu with respect to D+ into K- pi+
mu+ nu and D+ into K*(1430)^0 mu+ nu with respect to D+ into K- pi+ mu+ nu,
respectively.Comment: 14 page
- …