1,130 research outputs found
Spacecraft Radiator Freeze Protection Using a Regenerative Heat Exchanger
An active thermal control system architecture has been modified to include a regenerative heat exchanger (regenerator) inboard of the radiator. Rather than using a radiator bypass valve a regenerative heat exchanger is placed inboard of the radiators. A regenerator cold side bypass valve is used to set the return temperature. During operation, the regenerator bypass flow is varied, mixing cold radiator return fluid and warm regenerator outlet fluid to maintain the system setpoint. At the lowest heat load for stable operation, the bypass flow is closed off, sending all of the flow through the regenerator. This lowers the radiator inlet temperature well below the system set-point while maintaining full flow through the radiators. By using a regenerator bypass flow control to maintain system setpoint, the required minimum heat load to avoid radiator freezing can be reduced by more than half compared to a radiator bypass system
A new technique for oral endotracheal airway access in rabbits under fluoroscopic control: an easy way for drug administration in chronic experiments
Self-Regulation, Self-Efficacy, and Learning Disabilities
This chapter will discuss the roles of self-regulation and self-efficacy in students with learning disabilities. The guiding conceptual framework is based in social cognitive theory. In this theory, self-efficacy is a key motivational variable and self-regulation is a means for persons to develop a sense of agency, or the belief that they can exert a large degree of control over outcomes in their lives. Following a description of the theory, research is presented showing the operation of self-regulation and self-efficacy in students with learning disabilities. Future research directions are suggested, and implications of theory and research for educational practice are discussed
Ionospheric assimilation techniques for ARGOS Low-Resolution Airglow and Aurora Spectrograph (LORAAS) tomographically reconstructed equatorial electron density profiles
Electrophysiological characterization of activation state-dependent Cav2 channel antagonist TROX-1 in spinal nerve injured rats
AbstractPrialt, a synthetic version of Cav2.2 antagonist ω-conotoxin MVIIA derived from Conus magus, is the first clinically approved voltage-gated calcium channel blocker for refractory chronic pain. However, due to the narrow therapeutic window and considerable side effects associated with systemic dosing, Prialt is only administered intrathecally. N-triazole oxindole (TROX-1) is a novel use-dependent and activation state-selective small-molecule inhibitor of Cav2.1, 2.2 and 2.3 calcium channels designed to overcome the limitations of Prialt. We have examined the neurophysiological and behavioral effects of blocking calcium channels with TROX-1. In vitro, TROX-1, in contrast to state-independent antagonist Prialt, preferentially inhibits Cav2.2 currents in rat dorsal root ganglia (DRG) neurons under depolarized conditions. In vivo electrophysiology was performed to record from deep dorsal horn lamina V/VI wide dynamic range neurons in non-sentient spinal nerve-ligated (SNL) and sham-operated rats. In SNL rats, spinal neurons exhibited reduced responses to innocuous and noxious punctate mechanical stimulation of the receptive field following subcutaneous administration of TROX-1, an effect that was absent in sham-operated animals. No effect was observed on neuronal responses evoked by dynamic brushing, heat or cold stimulation in SNL or sham rats. The wind-up response of spinal neurons following repeated electrical stimulation of the receptive field was also unaffected. Spinally applied TROX-1 dose dependently inhibited mechanically evoked neuronal responses in SNL but not sham-operated rats, consistent with behavioral observations. This study confirms the pathological state-dependent actions of TROX-1 through a likely spinal mechanism and reveals a modality selective change in calcium channel function following nerve injury
Bounds on the basic physical parameters for anisotropic compact general relativistic objects
We derive upper and lower limits for the basic physical parameters
(mass-radius ratio, anisotropy, redshift and total energy) for arbitrary
anisotropic general relativistic matter distributions in the presence of a
cosmological constant. The values of these quantities are strongly dependent on
the value of the anisotropy parameter (the difference between the tangential
and radial pressure) at the surface of the star. In the presence of the
cosmological constant, a minimum mass configuration with given anisotropy does
exist. Anisotropic compact stellar type objects can be much more compact than
the isotropic ones, and their radii may be close to their corresponding
Schwarzschild radii. Upper bounds for the anisotropy parameter are also
obtained from the analysis of the curvature invariants. General restrictions
for the redshift and the total energy (including the gravitational
contribution) for anisotropic stars are obtained in terms of the anisotropy
parameter. Values of the surface redshift parameter greater than two could be
the main observational signature for anisotropic stellar type objects.Comment: 18 pages, no figures, accepted for publication in CQ
Ionospheric Assimilation Techniques for ARGOS Low-Resolution Airglow and Aurora Spectrograph (LORAAS) Tomographically Reconstructed Equatorial Electron Density Profiles
The LORAAS instrument aboard the ARGOS satellite observes line-of-sight ultraviolet limb intensities from ionosphere and thermosphere airglow. This study uses tomographically reconstructed electron density profiles (EDPs) from the nightside emissions. The ionospheric reconstruction is performed using a two-dimensional O+ 1356Å radiative recombination forward model and discrete inverse theory. The forward model assumes a Chapman layer for the vertical electron density distribution from which h m F 2, N m F 2, and topside scale height are derived for every 90 s limb scan, which is equivalent to 5° resolution in latitude. Since ARGOS is in a near Sun-synchronous orbit, these EDPs form a latitude slice through the equatorial anomaly structures at approximately 0230 LT. These data reflect ongoing ionospheric processes, and it is necessary to assimilate or compare with a model that contains appropriate ionospheric evolution such as the ionospheric forecast model (IFM). This study addresses the reasonableness of both the reconstructed EDPs and the IFM in describing the equatorial anomalies\u27 diurnal and weather variability. The comparison of the LORASS EDPs with those of IFM for October 2000 show that the EDP reconstruction results compare favorably to the IFM EDPs in peak height and topside scale height. Additionally, the sector-to-sector climatology of the observed and modeled equatorial anomalies is similar to within the resolution of the instrument and model. The variability observed in each pass of the satellite is much larger than the IFM variability. The LORASS observation variability indicates that careful assessment of the representation error of the observations should be addressed through supplemental observations
A Semi-Kinetic Model of Plasmasphere Refilling Following Geomagnetic Storms and Comparison with Hydrodynamic Results
The objective of this paper is the development of a kinetic model for plasmasphere refilling following geomagnetic storms. The kinetic model is based on the ‘particle-in-cell’ method, a method based on the simulation of particle motion and thus well-suited to high altitude, low-density regimes, where the plasma transport equations are not valid. The model was validated with exact, analytical benchmarks, which are provided in this paper. The refilling results obtained from the kinetic model were then compared with results from a recently developed hydrodynamic solution methodology based on the ‘flux-corrected transport’ (FCT) method, and the limitations of hydrodynamic modeling for low-density flow at high altitudes were explored
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Finite-element analyses of blade and slot coating flows using an implicit pseudo-solid domain mapping technique coupled with unstructured grids
In coating processes (e.g. in blade coating) the flow domain inherently contains free surfaces and three-phase contact lines, and characteristic length scales of flow features in the dimension transverse to the web-movement vary by an order of magnitude or more from a fraction of a millimeter or more to tens of microns or less). The presence of free surfaces and three-phase contact lines, and the sudden changes of flow geometry and directions create difficulties in theoretical analyses of such flows. Though simulations of coating flows via finite-element methods using structured grids have been reportedly demonstrated in the literature, achieving high efficiency of such numerical experiments remains a grand challenge -- mainly due to difficulties in local mesh-refinement and in avoiding unacceptably distorted grids. High efficiency of computing steady flow fields under various process conditions is crucial in shortening turn-around time in design and optimization of coating-flow processes. In this paper we employ a fully-implicit, pseudo-solid, domain mapping technique coupled with unstructured meshes to analyze blade and slot coating flows using Galerkin`s method with finite element basis functions. We demonstrate the robustness and efficiency of our unique technique in circumventing shortcomings of mesh-motion schemes currently being used in the coating-flow research community. Our goal is to develop an efficient numerical tool, together with a suitable optimization toolkit, that can be used routinely in design and optimization of coating-flow processes
A self‐consistent model of helium in the thermosphere
We have found that consideration of neutral helium as a major species leads to a more complete physics‐based modeling description of the Earth's upper thermosphere. An augmented version of the composition equation employed by the Thermosphere‐Ionosphere‐Electrodynamic General Circulation Model (TIE‐GCM) is presented, enabling the inclusion of helium as the fourth major neutral constituent. Exospheric transport acting above the upper boundary of the model is considered, further improving the local time and latitudinal distributions of helium. The new model successfully simulates a previously observed phenomenon known as the “winter helium bulge,” yielding behavior very similar to that of an empirical model based on mass spectrometer observations. This inclusion has direct consequence on the study of atmospheric drag for low‐Earth‐orbiting satellites, as well as potential implications on exospheric and topside ionospheric research.Key PointsTIE‐GCM has been modified to account for neutral heliumSeasonal behavior is successfully capturedNeutral densities from the new model agree well with previous observationsPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/113723/1/jgra51979.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/113723/2/jgra51979_am.pd
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