4,136 research outputs found

    Phenol as a Non-aqueous Solvent

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    1017-101

    Radar backscatter and rocket probe measurements of electron temperature above Arecibo

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    Comparison of radar backscatter and rocket probe measurements of ionospheric electron temperatur

    Antimicrobial susceptibility pattern of bacterial isolates in patients of chronic suppurative otitis media in a tertiary care hospital in India

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    Background: Chronic suppurative otitis media (CSOM) is a massive public health problem in developing countries like India, especially among low socio-economic class because of malnutrition, overcrowding, poor hygiene, inadequate health care and recurrent upper respiratory tract infections. CSOM cases unless managed effectively may land into various complications such as persistent otorrhoea, hearing impairment, mastoiditis, labyrinthitis, facial nerve paralysis to more serious intracranial abscesses.Methods: The study was carried out in a tertiary care hospital from January 2017 to December 2017 with an aim to determine the microbiological profile of ear discharge in patients suffering from CSOM and their antimicrobial susceptibility pattern using Kirby Bauer disc diffusion method.Results: Out of 630 samples processed, 407 (64.6%) samples were culture positive. Most common organism isolated was Pseudomonas spp. (43.2%) followed by S. aureus (39.1%). Most of isolates recovered were multidrug resistant.Conclusions: Management of CSOM consists mainly of eradicating infection and closure of tympanic membrane. Periodic monitoring of bacterial isolates and their antibiotic susceptibility pattern is necessary for administering appropriate antibiotics as empirical treatment and also helps in reducing the potentially disabling and fatal complications of CSOM

    Iontophoresis: A Potential Emergence of a Transdermal Drug Delivery System

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    The delivery of drugs into systemic circulation via skin has generated much attention during the last decade. Transdermal therapeutic systems propound controlled release of active ingredients through the skin and into the systemic circulation in a predictive manner. Drugs administered through these systems escape first-pass metabolism and maintain a steady state scenario similar to a continuous intravenous infusion for up to several days. However, the excellent impervious nature of the skin offers the greatest challenge for successful delivery of drug molecules by utilizing the concepts of iontophoresis. The present review deals with the principles and the recent innovations in the field of iontophoretic drug delivery system together with factors affecting the system. This delivery system utilizes electric current as a driving force for permeation of ionic and non-ionic medications. The rationale behind using this technique is to reversibly alter the barrier properties of skin, which could possibly improve the penetration of drugs such as proteins, peptides and other macromolecules to increase the systemic delivery of high molecular weight compounds with controlled input kinetics and minimum inter-subject variability. Although iontophoresis seems to be an ideal candidate to overcome the limitations associated with the delivery of ionic drugs, further extrapolation of this technique is imperative for translational utility and mass human application

    Cortical venous thrombosis – a rare complication of tuberculous meningitis

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    Occlusion of the central veins and sinuses occurs owing to thrombus, thrombophlebitis, or tumours. Cerebral venous thrombosis (CVT) is less frequent than arterial thrombosis, but can produce a cascade of sequelae and may be fatal. The usual predisposing factors for CVT include infections, pregnancy and puerperium, hypercoagulable states, etc. Many infectious causes are related to CVT, but a review of literature showed only few cases related to tuberculosis. Vascular changes consisting of arterial narrowing with or without occlusion are frequently seen at autopsy in cases of tuberculous meningitis. We report one such case of tuberculous meningitis where the patient developed cortical venous thrombosis after 5 days of illness. She was treated empirically, initially, till confirmation of the diagnosis and later was put on antitubercular drugs along with prednisolone therapy and anticoagulation, which led to complete recovery. Thus, if treated aggressively and in time, tuberculous meningitis and its complications are completely curable. Keywords: Tuberculous meningitis; Cortical venous thrombosis; Magnetic resonance venogram; Rare complication of TBMInternet Journal of Medical Update. 2013 January;8(1):31-3

    INTERNATIONAL JOURNAL OF ENGINEERING SCIENCES & MANAGEMENT INVESTIGATIONS OF A BOW TIE MICROSTRIP ANTENNA IN WIRE LESS APPLICATION

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    Abstract This paper presents a study on use of micro strip antenna and Planar Inverted-F Antenna in wireless communication. A triangular shaped micro strip antenna and Planar Inverted-F Antenna design is presented in this paper which can be use for wireless communication. The basic problem with micro strip antenna and Planar Inverted-F Antenna is its lower bandwidth, by making appropriate changes in antenna design this problem can be solved for some instant. In this paper technique of facilitation is used for enhancing the bandwidth of presented antenna

    NLO-QCD Corrections to Dilepton Production in the Randall-Sundrum Model

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    The dilepton production process at hadron colliders in the Randall-Sundrum (RS) model is studied at next-to-leading order in QCD. The NLO-QCD corrections have been computed for the virtual graviton exchange process in the RS model, in addition to the usual gamma, Z-mediated processes of standard Drell-Yan. K-factors for the cross-sections at the LHC and Tevatron for differential in the invariant mass, Q, and the rapidity, Y, of the lepton pair are presented. We find the K-factors are large over substantial regions of the phase space.Comment: 24 pages, 12 figure

    Phenomenology of Noncommutative Field Theories

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    Experimental limits on the violation of four-dimensional Lorentz invariance imply that noncommutativity among ordinary spacetime dimensions must be small. In this talk, I review the most stringent bounds on noncommutative field theories and suggest a possible means of evading them: noncommutativity may be restricted to extra, compactified spatial dimensions. Such theories have a number of interesting features, including Abelian gauge fields whose Kaluza-Klein excitations have self couplings. We consider six-dimensional QED in a noncommutative bulk, and discuss the collider signatures of the model.Comment: 7 pages RevTeX, 4 eps figures, Invited plenary talk, IX Mexican Workshop on Particles and Fields, November 17-22, 2003, Universidad de Colima, Mexic

    Antihypertensive and Antioxidant Action of Amlodipine and Vitamin C in Patients of Essential Hypertension

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    The etiology of essential hypertension includes increased oxidative stress. The role of antihypertensive drug amlodipine as an antioxidant and the benefit of addition of vitamin C, an antioxidant to antihypertensive therapy were studied. Forty male patients of essential hypertension were randomly divided into two groups and treated with 5 mg amlodipine. In addition one group also received 1000 mg vitamin C (as two 500 mg tablets) once daily for three months. Although blood pressure decreased in both groups, the systolic blood pressure in patients given vitamin C was less (126.4 ± 7.47) compared to the other group (130.9 ± 7.27). A decrease in malondialdehyde, an increase in erythrocyte sodium-potassium adenosine triphosphatase (Na+ K+ ATPase) and an increase in the superoxide dismutase levels were observed in both groups. The increase in SOD was statistically more in the patients given vitamin C in addition to amlodipine (0.1717 ± 0.0150 compared to 0.152 ± 0.0219 units/100 ml assay). In spite of the known antihypertensive, antioxidant activity, similarity in correcting endothelial dysfunction independently, giving the two drugs together and early introduction of vitamin C perhaps decreases oxidative stress and augments the antioxidant status. This may prevent further vascular damage due to oxidative stress, leading to a better prognosis in essential hypertension patients

    Cosmic Censorship in Higher dimension II

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    Generalizing earlier results on dust collapse in higher dimensions, we show here that cosmic censorship can be restored in gravitational collapse with tangential pressure present if we take the spacetime dimension to be N6N\ge6. This is under conditions to be motivated physically, such as the smoothness of initial data from which the collapse develops. The models considered here incorporating a non-zero tangential pressure include the Einstein cluster spacetime.Comment: 7 pages,1 figure,revtex
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