4 research outputs found
Synthesis, characterization and antimicrobial screening of some novel chalcones and their derivatives
1642-1648 Synthesis of some novel
2-(4-(allyloxy)-3-methoxyphenyl)-4H-chromen-4-ones
5a-f and
2-(4-(allyloxy)-3-methoxyphenyl)-3-chloro-4H-chromen-4-ones
6a-f by oxidative cyclisation of (E)-3-(4-allyloxy)-3-methoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-ones
using DMSO/I2 and DMSO/CuCl2 at reflux condition has been
carried out. A useful and efficient synthetic strategy for the synthesis of
4-allyloxy-3-methoxyphenyl chromones has been reported. The synthesized
compounds have been characterized by melting point, FT-IR, NMR and EI-MS
spectral data. The synthesized compounds have been evaluated for their
antibacterial and antifungal activities. Most of the compounds are found to be
of comparable potency when compared with the reference standard drugs