There\u27ll be a Rainbow in the Sky for You

https://digitalcommons.library.umaine.edu/mmb-vp/6370/thumbnail.jp

That Creepy Weepy Feeling

https://digitalcommons.library.umaine.edu/mmb-vp/6414/thumbnail.jp

Multiyear contracting for non-major weapon systems

The focus of this thesis is to determine the use of multiyear contracting for purchasing non-major weapon systems. The intent of this research is to analyze long-term procurement of supplies and equipment, specifically valves, pumps and compressors. The purpose of the study is to determine the level at which multiyear contracting procedures are used to acquire supplies and equipment. The study will determine factors which promote or restrict the utilization of multiyear contracts. Surveys and interviews were used to assess the use of long-term procedures for buying supplies. The conclusion indicates that multiyear contracting is limited when purchasing repair parts for weapon systems, and there are alternative methods used to procure repair parts on a long-term basis. Recommendations include making policy and procedural changes to promote the increased usage of multiyear contracts, and implementing programs to market the benefits of long-term contracting, especially multiyear contractinghttp://archive.org/details/multiyearcontrac00johnLieutenant, United States NavyApproved for public release; distribution is unlimited

Gentamicin Pharmacokinetics in Term Neonates Receiving Extracorporeal Membrane Oxygenation

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90148/1/j.1875-9114.1992.tb02667.x.pd

Relativistic Xα–scattered‐wave calculations for the uranyl ion

Relativistic Xα–scattered‐wave molecular orbital calculations have been carried out on the uranyl ion UO22+. The calculated orbital eigenvalues are in good agreement with the results of a recent x‐ray photoelectron spectroscopy study of uranyl compounds. An interpretation of the optical spectrum of the uranyl ion in terms of a Hund’s case (c) (ω, ω) coupling scheme is given

The Rb binding domain of HPV31 E7 is required to maintain high levels of DNA repair factors in infected cells

Human papillomaviruses (HPV) exhibit constitutive activation of ATM and ATR DNA damage response (DDR) pathways, which are required for productive viral replication. Expression of HPV31 E7 alone is sufficient to activate the DDR through an unknown mechanism. Here, we demonstrate that the E7 Rb binding domain is required to increase levels of many DDR proteins, including ATM, Chk2, Chk1, the MRN components MRE11, Rad50, and NBS1, as well as the homologous recombination repair proteins BRCA1 and Rad51. Interestingly, we have found that the increase in these DNA repair proteins does not occur solely at the level of transcription, but that E7 broadly increases the half-life of these DDR factors, a phenotype that is lost in the E7 Rb binding mutant. These data suggest that HPV-31 upregulates DNA repair factors necessary for replication by increasing protein half-life in a manner requiring the E7 Rb binding domain

Education of Children with Disabilities: Voices from Around the World

Education of Children with Disabilities: Voices from Around the World combines research on children with disabilities and women/girls with disabilities. These projects provided opportunities to interview disability professionals, policy-makers and persons with disabilities from around the world with the purpose of learning about needs, issues and services, in diverse countries. A unique international analysis, this research compares various cultural responses on the education of children with disabilities emphasizing the girl child. Discussion includes findings based on 177 interviews of disability professionals from over 57 countries including the stated reasons and consequences of lost educational opportunities. Techniques locating participants included internet searches, literature reviews, and personal referrals. Interviewees were selected based on their experiences with childhood disabilities and/or women and girls with disabilities. Many interviewees were persons with disabilities who shared their personal experiences. Through a qualitative analysis of the interviews some of the most prevalent themes that emerged were the importance of education and the disproportionate negative effect of disability on females. To measure the strength of these themes, an electronic survey was created using a Likert scale to measure the strength of agreement of each participant with the issues identified. Survey ratings added quantitative confirmation to the rich qualitative interviews. The education themes identified include school exclusion and barriers to education with a particular focus on the girl child, education quality and inclusive education

Prospective Evaluation of Two Dosing Equations for Theophylline in Premature Infants

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90141/1/j.1875-9114.1996.tb02995.x.pd

Bilirubin Present in Diverse Angiosperms

Background and aims: Bilirubin is an orange-yellow tetrapyrrole produced from the breakdown of heme by mammals and some other vertebrates. Plants, algae, and cyanobacteria synthesize molecules similar to bilirubin, including the protein-bound bilins and phytochromobilin which harvest or sense light. Recently, we discovered bilirubin in the arils of Strelitzia nicolai, the White Bird of Paradise Tree, which was the first example of this molecule in a higher plant. Subsequently, we identified bilirubin in both the arils and flowers of Strelitzia reginae, the Bird of Paradise Flower. In the arils of both species, bilirubin is present as the primary pigment, and thus functions to produce color. Previously, no tetrapyrroles were known to generate display color in plants. We were therefore interested in determining whether bilirubin is broadly distributed in the plant kingdom, and whether it contributes to color in other species