Nutrient Data in Time for the New Year

Federal rules published in 2010 require specific meat and poultry products to carry new nutrition information starting January 2, 2012. USDA’s Food Safety and Inspection Service (FSIS) announced that the new rules will make important nutrition information readily available to consumers on 40 of the most popular cuts of meat and poultry. Two timely data sets provided by the Agricultural Research Service’s Nutrient Data Laboratory (NDL) in Beltsville, Maryland, are being used by the beef and pork industries to provide the new Nutrition Facts labels for their products. Previously, NDL researchers, in collaboration with representatives of the beef and pork industries and various universities, conducted several studies designed to update and expand the available nutrient data on current beef and pork cuts and products. The results led to a major update of beef and pork nutrient data in the U.S. Department of Agriculture’s National Nutrient Database for Standard Reference Release 24. Called “SR24” for short, the database is the major authoritative source of information about U.S. food composition. The study results have also been incorporated into two downloadable data sets. SR24 includes more than 7,500 food items and is managed by NDL, which is part of the ARS Beltsville [Maryland] Human Nutrition Research Center. NDL is headed by research leader Joanne Holden

University Archives & Community Organizations: Ensuring Access through Collaboration

In 2011, to further our community-engaged mission, UASC began to focus on working with, promoting, and assisting community archives in the greater Boston area through facilitating cross-organization collaboration and access to informational, educational, and practical resources relevant to archival procedures and best practices. The guiding tenets behind this continuing commitment emerged, in part, from UASC’s multifaceted collaboration with The Irish Ancestral Research Association (TIARA), a local nonprofit organization established to develop and promote the growth, study, and exchange of ideas among people and organizations interested in Irish genealogical and historical research and education. Our collaboration with TIARA formally began in 2011, driven by a unique collection, the records of the Massachusetts Catholic Order of Foresters (MCOF)

Processing Manual for Archival and Manuscript Collections

University Archives and Special Collections collects and preserves materials related to the history of UMass Boston, providing academic research support for the university community. University Archives and Special Collections recognizes a formal commitment to working with, promoting, and assisting community archives in the Greater Boston area through facilitating cross-organization collaboration and access to informational, educational, and practical resources relevant to archival procedures and best practices. This manual is intended to be used as a training guide for graduate-level interns, volunteers, and professional archivists new to working in University Archives and Special Collections (UASC). It is also intended to bring consistent practices to UASC and to serve as a reference source for staff

University Archives and Community Organizations: Ensuring Access through Collaboration

How can a university archives establish a successful ongoing relationship with a community organization? What are the benefits and challenges of such a collaboration? University of Massachusetts Boston’s Archives and Special Collections (UASC) explored these questions while working with The Irish Ancestral Research Association (TIARA) to preserve and provide access to 79,000 mortuary records from the Massachusetts Catholic Order of Foresters. Elements of the collaboration included shifting stewardship of the records from the Foresters to TIARA to UMass Boston, integrating TIARA’s efforts in processing and indexing the records into the Archives’ workflow, providing in-person and electronic access to the records, and hosting public events that celebrate the partnership and educate the public about the records. This poster illustrates the lessons learned during the records’ journey from an active business to a community organization to a university’s Archives and Special Collections

Investigating bullying as a predictor of suicidality in a clinical sample of adolescents with Autism Spectrum Disorder

For typically developing adolescents, being bullied is associated with increased risk of suicidality. Although adolescents with autism spectrum disorder (ASD) are at increased risk of both bullying and suicidality, there is very little research that examines the extent to which an experience of being bullied may increase suicidality within this specific population. To address this, we conducted a retrospective cohort study to investigate the longitudinal association between experiencing bullying and suicidality in a clinical population of 680 adolescents with ASD. Electronic health records of adolescents (13–17 years), using mental health services in South London, with a diagnosis of ASD were analyzed. Natural language processing was employed to identify mentions of bullying and suicidality in the free text fields of adolescents' clinical records. Cox regression analysis was employed to investigate the longitudinal relationship between bullying and suicidality outcomes. Reported experience of bullying in the first month of clinical contact was associated with an increased risk suicidality over the follow‐up period (hazard ratio = 1.82; 95% confidence interval = 1.28–2.59). In addition, female gender, psychosis, affective disorder diagnoses, and higher intellectual ability were all associated with suicidality at follow‐up. This study is the first to demonstrate the strength of longitudinal associations between bullying and suicidality in a clinical population of adolescents with ASD, using automated approaches to detect key life events within clinical records. Our findings provide support for identifying and dealing with bullying in schools, and for antibullying strategy's incorporation into wider suicide prevention programs for young people with ASD. Autism Res 2020, 13: 988‐997. © 2020 The Authors. Autism Research published by International Society for Autism Research published by Wiley Periodicals, Inc. LAY SUMMARY: We investigated the relationship between bullying and suicidality in young people with autism spectrum disorder (ASD). We examined the clinical records of adolescents (aged 13–18 years old) with ASD in South London who were receiving treatment from Child and Adolescent Mental Health Services. We found that if they reported being bullied in the first month after they were first seen by mental health services, they were nearly twice as likely to go on to develop suicidal thoughts or behaviors

“Save Our History!” Collaborating to Preserve the Past at UMass Boston

Sparked by the 50th anniversary of the founding of the University of Massachusetts Boston in June 1964, University Archives and Special Collections (UASC) staff in the Joseph P. Healey Library collaborated with departments across campus to carry out a wide range of initiatives, all focused on locating, accessioning, preserving, and sharing the physical evidence of the university’s history. This poster outlines the various collecting activities, outreach methods, digitization projects, and dogged detective work that resulted in the addition of more than 2,500 linear feet of unique historic materials to the University Archives, as well as a number of well-received public events and exhibitions

Climate Change – Refining the Impacts for Ireland: STRIVE Report (2001-CD-C3-M1) ISBN: 978-1-84095-297-1

International Context: As a mid-latitude country Ireland can expect its future temperature changes to mirror quite closely those of the globe as a whole. Best estimates of global temperature change by the end of the present century are currently in the region 1.8–4.0°C1. Regional Context: Weighted Ensemble Downscaling from Global Climate Models Global climate models (GCMs) have greatly improved in reliability and resolution as computing power has increased and better inputs from earth observation have become available. Despite this, they remain too coarse in terms of their grid size to enable climate scenarios at the scale necessary for impact analysis to be achieved. This study employs a statistical downscaling approach to overcome these difficulties and also to provide new information on model uncertainty with a view to reducing uncertainty in key sectors such as water resource management, agriculture and biodiversity

Multiplex quantitative PCR for single-reaction genetically modified (GM) plant detection and identification of false-positive GM plants linked to Cauliflower mosaic virus (CaMV) infection.

BACKGROUND:Most genetically modified (GM) plants contain a promoter, P35S, from the plant virus, Cauliflower mosaic virus (CaMV), and many have a terminator, TNOS, derived from the bacterium, Agrobacterium tumefaciens. Assays designed to detect GM plants often target the P35S and/or TNOS DNA sequences. However, because the P35S promoter is derived from CaMV, these detection assays can yield false-positives from non-GM plants infected by this naturally-occurring virus. RESULTS:Here we report the development of an assay designed to distinguish CaMV-infected plants from GM plants in a single multiplexed quantitative PCR (qPCR) reaction. Following initial testing and optimization via PCR and singleplex-to-multiplex qPCR on both plasmid and plant DNA, TaqMan qPCR probes with different fluorescence wavelengths were designed to target actin (a positive-control plant gene), P35S, P3 (a CaMV-specific gene), and TNOS. We tested the specificity of our quadruplex qPCR assay using different DNA extracts from organic watercress and both organic and GM canola, all with and without CaMV infection, and by using commercial and industrial samples. The limit of detection (LOD) of each target was determined to be 1% for actin, 0.001% for P35S, and 0.01% for both P3 and TNOS. CONCLUSIONS:This assay was able to distinguish CaMV-infected plants from GM plants in a single multiplexed qPCR reaction for all samples tested in this study, suggesting that this protocol is broadly applicable and readily transferrable to any interested parties with a qPCR platform

Anti-Cocaine Compositions and Treatment

Embodiments of the invention disclosed herein generally relate to anti-cocaine therapeutics. Specifically, some embodiments of the invention relate to highly efficient, thermostable, and long-lasting cocaine esterase (CocE) mutants that can protect against the toxic and reinforcing effects of cocaine in subjects. Provided herein are mutant CocE polypeptides displaying thermostable esterase activity. Also provided are methods of treating cocaine-induced conditions in a subject in need via administration of mutant CocE as well as methods for high-throughput screening of candidate esterase polypeptides