KINEMATICAL PARAMETERS CONTRIBUTION TO THE FLIGHT HEIGHT USING ONE-FOOT OR TWO-FOOT TAKE-OFF

The purpose of this study was to investigate which of the kinematics parameters most contribute to vertical flight heights. Eight subjects were filmed using Sony digital camera with 25 images from the sagittal plane during execution of the following vertical jump conditions: free two-foot take-off, free one-foot take-off, fixed arm two-foot take-off, and fixed arm one-foot take-off. Arm swing contribution, leg swing contribution, height of centre of gravity at take-off (HCGTO), vertical velocity at take-off, arm’s angular momentum, work, and power were analyzed in each condition using stick figures according to Clauser, McConville, and Young (1969). Correlation and regression analysis indicated that HCGTO contributed the most to the flight heights in all conditions

An Audio-visual Solution to Sound Source Localization and Tracking with Applications to HRI

Robot audition is an emerging and growing branch in the robotic community and is necessary for a natural Human-Robot Interaction (HRI). In this paper, we propose a framework that integrates advances from Simultaneous Localization And Mapping (SLAM), bearing-only target tracking, and robot audition techniques into a unifed system for sound source identification, localization, and tracking. In indoors, acoustic observations are often highly noisy and corrupted due to reverberations, the robot ego-motion and background noise, and possible discontinuous nature of them. Therefore, in everyday interaction scenarios, the system requires accommodating for outliers, robust data association, and appropriate management of the landmarks, i.e. sound sources. We solve the robot self-localization and environment representation problems using an RGB-D SLAM algorithm, and sound source localization and tracking using recursive Bayesian estimation in the form of the extended Kalman Filter with unknown data associations and an unknown number of landmarks. The experimental results show that the proposed system performs well in the medium-sized cluttered indoor environment

MyoRing implantation in keratoconic patients: 3 years follow-up data

Purpose: To evaluate long-term follow-up data on implantation of a full-ring intra-corneal implant (MyoRing) for management of keratoconus. Methods: A total of 40 keratoconic eyes of 37 consecutive patients who had undergone MyoRing implantation using the Pocket Maker microkeratome (Dioptex, GmbH, Linz, Austria) and completed 3 years of follow-up appointments were included in this retrospective study. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refraction and keratometry (K) readings were measured and evaluated preoperatively, and 3 years, postoperatively. Results: No intraoperative complications were observed in this case series. Three years postoperatively, there was a significant improvement in UDVA, CDVA, K readings, spherical equivalent (SE), and manifest sphere and cylinder (P < 0.05 for all comparisons). UDVA was significantly improved from 1.14 ± 0.27 to 0.30 ± 0.21 LogMAR (P = 0.001), CDVA was also improved from 0.52 ± 0.23 to 0.18 ± 0.12 LogMAR (P = 0.001), SE was decreased by 4.35 diopters (D) and average keratometric values were reduced by 2.34 D (P = 0.001). Overall, 81 of subjects were moderately to highly satisfied 3 years after surgery and 64.90 agreed to have the fellow eye implanted with MyoRing. Conclusion: MyoRing implantation using the Pocket Maker microkeratome was found to be a minimally invasive procedure for improving visual acuity and refraction in the majority of the patients with keratoconus. © 2016 Journal of Ophthalmic and Vision Research

LASEK for the correction of hyperopia with mitomycin C using SCHWIND AMARIS excimer laser: one-year follow-up

AIM: To evaluate the efficacy, safety and predictability of laser-assisted sub-epithelial keratectomy (LASEK) for the correction of hyperopia using the SCHWIND AMARIS platform. METHODS: This retrospective single-surgeon study includes 66 eyes of 33 patients with hyperopia who underwent LASEK with mitomycin C (MMC). The median age of patients was 35.42±1.12y (ranging 18 to 56y). In each patient LASEK was performed using SCHWIND AMARIS excimer laser. Postoperatively clinical outcomes were evaluated in terms of predictability, safety, efficacy, subjective and objective refractions, uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA) and adverse events. RESULTS: The mean baseline refraction was 3.2±1.6 diopters (D) (ranging 0 to 7 D). The mean pre-operative and postoperative spherical equivalent (SE) were 2.34±1.76 (ranging -1.25 to 7 D) and 0.30±0.84 (ranging -0.2 to 0.8 D) respectively (P=0.001). The mean hyperopia was 0.63±0.84 D (ranging -1.75 to 2.76 D) 6 to 12mo postoperatively. Likewise, the mean astigmatism was 0.68±0.43 D (range 0 to 2 D) with 51 (77.3) and 15 (22.7) eyes within ±1 and ±0.50 D respectively. The safety index and efficacy index were 1.08 and 1.6 respectively. CONCLUSION: LASEK using SCHWIND AMARIS with MMC yields good visual and refractive results for hyperopia. Moreover, there were no serious complications. Copyright 2015 by the IJO Press

Geographical trends in research: a preliminary analysis on authors' affiliations

In the last decade, research literature reached an enormous volume with an unprecedented current annual increase of 1.5 million new publications. As research gets ever more global and new countries and institutions, either from academia or corporate environment, start to contribute with their share, it is important to monitor this complex scenario and understand its dynamics. We present a study on a conference proceedings dataset extracted from Springer Nature Scigraph that illustrates insightful geographical trends and highlights the unbalanced growth of competitive research institutions worldwide. Results emerged from our micro and macro analysis show that the distributions among countries of institutions and papers follow a power law, and thus very few countries keep producing most of the papers accepted by high-tier conferences. In addition, we found that the annual and overall turnover rate of the top 5, 10 and 25 countries is extremely low, suggesting a very static landscape in which new entries struggle to emerge. Finally, we highlight the presence of an increasing gap between the number of institutions initiating and overseeing research endeavours (i.e. first and last authors' affiliations) and the total number of institutions participating in research. As a consequence of our analysis, the paper also discusses our experience in working with affiliations: an utterly simple matter at first glance, that is instead revealed to be a complex research and technical challenge yet far from being solved

Herbal-based drugs for dry eye; treatment and adverse reaction

33-40Dry eye syndrome is one of the most common types of eye diseases. Due to the significant prevalence of the disease, there is an important need for treatment of dry eye in a simple but efficient way. Artificial tears are the most common agents used for treating dry eye but are not very useful. In recent years, the use of herbal remedies has attracted much attention, because the process of producing most herbal remedies is simple, inexpensive and has fewer side effects. In many clinical studies, the potential interactions between medicines and herbs have been demonstrated. According to reports, some herbal products have the potential to be used for the treatment of dry eye while the use of certain products can lead to this syndrome. In this review, we have listed some of the herbal drugs and components which can prevent or treat the dry eye or cause it

Optically-Induced Symmetry Breaking via Nonlinear Phononics

Optical nonlinearities in solids reveal information about both the in-plane rotational and out-of-plane inversion symmetries of a crystal. In the van der Waals material hexagonal boron nitride (hBN) both these symmetries and the linear vibrational properties have led to the rich physics of mid-infrared phonon-polaritons. However, the role of strong electron-phonon nonlinearities requires further study. In this work, we investigate both theoretically and experimentally the rich interplay of phonon anharmonicity and symmetry in phonon-polariton mediated nonlinear optics. We show that large enhancements (>30x) of third-harmonic generation occur for incident femtosecond pulses that are resonant with the hBN transverse optical phonons. In addition, we predict and observe large transient sub-picosecond duration second-harmonic signals during resonant excitation, which in equilibrium is forbidden by symmetry. This surprising result indicates that instantaneous crystal inversion symmetry breaking can be optically induced and controlled via phonon interactions by both the power and polarization of the pump laser

FLYWCH1, a novel suppressor of nuclear b-catenin, regulates migration and morphology in colorectal cancer

© 2018 American Association for Cancer Research. Wnt/b-catenin signaling plays a critical role during development of both normal and malignant colorectal cancer tissues. Phosphorylation of b-catenin protein alters its trafficking and function. Such conventional allosteric regulation usually involves a highly specialized set of molecular interactions, which may specifically turn on a particular cell phenotype. This study identifies a novel transcription modulator with an FLYWCH/Zn-finger DNA-binding domain, called "FLYWCH1." Using a modified yeast-2-hybrid based Ras-Recruitment system, it is demonstrated that FLYWCH1 directly binds to unphosphorylated (nuclear) b-catenin efficiently suppressing the transcriptional activity of Wnt/ b-catenin signaling that cannot be rescued by TCF4. FLYWCH1 rearranges the transcriptional activity of b-catenin/TCF4 to selectively block the expression of specific downstream genes associated with colorectal cancer cell migration and morphology, including ZEB1, EPHA4, and E-cadherin. Accordingly, overexpression of FLYWCH1 reduces cell motility and increases cell attachment. The expression of FLYWCH1 negatively correlates with the expression level of ZEB1 and EPHA4 in normal versus primary and metastatic colorectal cancer tissues in patients. Thus, FLYWCH1 antagonizes b-catenin/TCF4 signaling during cell polarity/migration in colorectal cancer. Implications: This study uncovers a new molecular mechanism by which FLYWCH1 with a possible tumor suppressive role represses b-catenin-induced ZEB1 and increases cadherin-mediated cell attachment preventing colorectal cancer metastasis

Tools for BIM-GIS integration (IFC georeferencing and conversions): Results from the GeoBIM benchmark 2019

The integration of 3D city models with Building Information Models (BIM), coined as GeoBIM, facilitates improved data support to several applications, e.g., 3D map updates, building permits issuing, detailed city analysis, infrastructure design, context-based building design, to name a few. To solve the integration, several issues need to be tackled and solved, i.e., harmonization of features, interoperability, format conversions, integration of procedures. The GeoBIM benchmark 2019, funded by ISPRS and EuroSDR, evaluated the state of implementation of tools addressing some of those issues. In particular, in the part of the benchmark described in this paper, the application of georeferencing to Industry Foundation Classes (IFC) models and making consistent conversions between 3D city models and BIM are investigated, considering the OGC CityGML and buildingSMART IFC as reference standards. In the benchmark, sample datasets in the two reference standards were provided. External volunteers were asked to describe and test georeferencing procedures for IFC models and conversion tools between CityGML and IFC. From the analysis of the delivered answers and processed datasets, it was possible to notice that while there are tools and procedures available to support georeferencing and data conversion, comprehensive definition of the requirements, clear rules to perform such two tasks, as well as solid technological solutions implementing them, are still lacking in functionalities. Those specific issues can be a sensible starting point for planning the next GeoBIM integration agendas