Acousto-optic laser optical feedback imaging

We present a photon noise and diffraction limited imaging method combining the imaging laser and ultrasonic waves. The laser optical feedback imaging (LOFI) technique is an ultrasensitive imaging method for imaging objects through or embedded within a scattering medium. However, LOFI performances are dramatically limited by parasitic optical feedback occurring in the experimental setup. In this work, we have tagged the ballistic photons by an acousto-optic effect in order to filter the parasitic feedback effect and to reach the theoretical and ultimate sensitivity of the LOFI technique. We present the principle and the experimental setup of the acousto-optic laser optical feedback imaging (AO-LOFI) technique, and we demonstrate the suppression of the parasitic feedback

Field theoretic formulation of a mode-coupling equation for colloids

The only available quantitative description of the slowing down of the dynamics upon approaching the glass transition has been, so far, the mode-coupling theory, developed in the 80's by G\"otze and collaborators. The standard derivation of this theory does not result from a systematic expansion. We present a field theoretic formulation that arrives at very similar mode-coupling equation but which is based on a variational principle and on a controlled expansion in a small dimensioneless parameter. Our approach applies to such physical systems as colloids interacting via a mildly repulsive potential. It can in principle, with moderate efforts, be extended to higher orders and to multipoint correlation functions

The hypothesis of the moving comb in frequency shifted feedback lasers

International audienceThe use of frequency-shifted feedback (FSF) lasers in optical metrology is based on a unique coherence property: the appearance of beats in the noise spectrum at the output of a two-beam interferometer, whose frequencies vary linearly with the path delay of the interferometer. A description of the output of a FSF laser as a moving comb of optical frequencies is generally admitted to explain these specific coherence properties. Here starting from the model of a passive FSF cavity seeded by spontaneous emission we give a rigorous description of the time-spectrum properties of FSF lasers and show that the moving comb exists only in the limit of small frequency shift

Plenoptic microscope based on laser optical feedback imaging (LOFI)

We present an overview of the performances of a plenoptic microscope which combines the high sensitivity of a laser optical feedback imaging setup , the high resolution of optical synthetic aperture and a shot noise limited signal to noise ratio by using acoustic photon tagging. By using an adapted phase filtering, this microscope allows phase drift correction and numerical aberration compensation (defocusing, coma, astigmatism ...). This new kind of microscope seems to be well adapted to make deep imaging through scattering and heterogeneous media

Assessment of biological role and insight into druggability of the Plasmodium falciparum protease plasmepsin V

Upon infecting a red blood cell (RBC), the malaria parasit

Under-expression Of Chemosensory Genes In Domiciliary Bugs Of The Chagas Disease Vector Triatoma Brasiliensis

In Latin America, the bloodsucking bugs Triatominae are vectors of Trypanosoma cruzi, the parasite that causes Chagas disease. Chemical elimination programs have been launched to control Chagas disease vectors. However, the disease persists because native vectors from sylvatic habitats are able to (re)colonize houses—a process called domiciliation. Triatoma brasiliensis is one example. Because the chemosensory system allows insects to interact with their environment and plays a key role in insect adaption, we conducted a descriptive and comparative study of the chemosensory transcriptome of T. brasiliensis samples from different ecotopes. Methodology/Principal Finding: In a reference transcriptome built using de novo assembly, we found transcripts encoding 27 odorant-binding proteins (OBPs), 17 chemosensory proteins (CSPs), 3 odorant receptors (ORs), 5 transient receptor potential channel (TRPs), 1 sensory neuron membrane protein (SNMPs), 25 takeout proteins, 72 cytochrome P450s, 5 gluthatione S-transferases, and 49 cuticular proteins. Using protein phylogenies, we showed that most of the OBPs and CSPs for T. brasiliensis had well supported orthologs in the kissing bug Rhodnius prolixus. We also showed a higher number of these genes within the bloodsucking bugs and more generally within all Hemipterans compared to the other species in the super-order Paraneoptera. Using both DESeq2 and EdgeR software, we performed differential expression analyses between samples of T. brasiliensis, taking into account their environment (sylvatic, peridomiciliary and domiciliary) and sex. We also searched clusters of co-expressed contigs using HTSCluster. Among differentially expressed (DE) contigs, most were under-expressed in the chemosensory organs of the domiciliary bugs compared to the other samples and in females compared to males. We clearly identified DE genes that play a role in the chemosensory system. Conclusion/Significance: Chemosensory genes could be good candidates for genes that contribute to adaptation or plastic rearrangement to an anthropogenic system. The domiciliary environment probably includes less diversity of xenobiotics and probably has more stable abiotic parameters than do sylvatic and peridomiciliary environments. This could explain why both detoxification and cuticle protein genes are less expressed in domiciliary bugs. Understanding the molecular basis for how vectors adapt to human dwellings may reveal new tools to control disease vectors; for example, by disrupting chemical communication. © 2016 Marchant et al.101

Pan-Africanism: a contorted delirium or a pseudonationalist paradigm? Revivalist critique

This essaic-article goes against established conventions that there is anything ethno-cultural (and hence national) about the so-called African tribes. Drawing largely from the culture history of precolonial/prepolitical Africans—that is, the Bantu/Cushitic-Ethiopians (Azanians)—the author has demonstrated vividly that far from being distinct ethno-culture national communities, the so-called tribes of African states are better considered subculture groups, whose regional culture practices erstwhile paid tribute to their nation’s main culture center in Karnak. For example, using the culture symbols and practices of some local groups and linking them to the predynastic and dynastic Pharaonic periods, I argued that there is compelling evidence against qualifying Africa’s tribes as distinct ethno-culture national entities. In genuine culture context, I stressed that the Ritual of Resurrection and its twin culture process of the mummification of deceased indigenous Pharaohs tend to suggest that the object of the Bantu/Cushitic-Ethiopians national culture was life (in its eternal manifestation) and then resurrection later, and that there are recurring (culturally sanctioned) ethical examples among the culture custodians of these subculture groups that generally pay tribute to the overarching culture norm. Furthermore, the fact that the Ritual of Resurrection began in the Delta region and ended at the Sources of the Nile, where the spirit of the deceased indigenous Pharaohs was introduced into the spiritual world of their ancestors, contradicts conventional perceptions that ancient Egypt was a distinct national community isolated from precolonial/prepolitical Africa/Azania