25 research outputs found
The impact of nonlinear stability and instability on the validity of the tangent linear model
Contraception With Long-acting Subdermal Implants. A Five-year Clinical Trial With Silastic Covered Rod Implants Containing Levonorgestrel
A total of 189 women volunteered to accept subdermal implants for contraception. The implants were "covered rods", consisting of a core rod containing equal parts by weight of levonorgestrel and polydimethylsiloxane and sealed inside a thin-walled tube of Silastic tubing with medical adhesive. In one study 78 women used 4 3cm rods (study 07) and in the other 111 women used 6 3cm rods. In 5 years of use there were no pregnancies in either group. Terminations because of menstrual problems were twice as frequent among the 4-rod users than among users of the 6 rods. Menstrual pattern analysis is presented for the two rod regimens and compared with the previously reported patterns for the 6-capsule regimen (NORPLANTR). Long-term in vivo release rates are also presented. © 1985.314351359Contraception with long acting subdermal implants: I. An effective and acceptable modality in international clinical trials (1978) Contraception, 18, pp. 315-333. , IThe Development of NORPLANT Implants (1983) Studies in Family Planning, 14, pp. 159-193Diaz, Pavez, Miranda, Robertson, Sivin, Croxatto, A Five-Year Clinical Trial of Levonorgestrel Silastic Implants (NORPLANT™) (1982) Contraception, 25, pp. 447-456Nash, Robertson, Moo-Young, Atkinson, Steroid Release from Silastic Capsules and Rods (1978) Contraception, 18, pp. 367-394Faundes, Mejias, DeLeon, Robertson, Alvarez, First year clinical experience with six levonorgestrel rods as subdermal contraception (1979) Contraception, 20, pp. 167-175Roy, Stanczyk, Mishell, Lumkin, Gentzschein, Clinical and Endocrinological Study of Continuous Levonorgestrel Administration from Subcutaneous Solid Polydimethylsiloxane Rods (1980) Contraception, 21, pp. 595-615Weiner, Johansson, Contraception with d-Norgestrel Silastic Rods: Plasma Levels of d-Norgestrel and Influence on the Ovarian Function (1976) Contraception, 14, pp. 551-562Robertson, Sivin, Nash, Braun, Dinh, Release Rates of Levonorgestrel from SilasticR Capsules. Homogenous Rods and covered Rods in Humans (1983) Contraception, 27, pp. 483-495Jain, Sivin, Life-Table Analysis of IUDs. Problems and Recommendations (1977) Studies in Family Planning, 8 (2)Faundes, Sivin, Stern, Long -Acting Contraceptive Implants, An Analysis of Menstrual Bleeding Patterns (1978) Contraception, 18, pp. 355-36
Levonorgestrel concentrations during use of levonorgestrel rod (LNG ROD) implants
10.1016/S0010-7824(96)00276-4Contraception55281-85CCPT