The Japanese oyster drill <i>Ocinebrellus inornatus</i> (Récluz, 1851) (Mollusca, Gastropoda, Muricidae), introduced to the Limfjord, Denmark

The predatory neogastropod Ocinebrellus inornatus was first reported from Europe in W France in 1995 and has since been detected at other sites in NW and N France and The Netherlands. It is native to the North Pacific where it preys on the Pacific oyster Crassostrea gigas. Here we report on the occurrence of the species in beds of European oysters (Ostrea edulis) in the Limfjord, NW Jutland, Denmark. The morphology-based identification has been confirmed by genetic analysis. The species was probably introduced with oysters imported from France in the 1970s and 1980s. The invasion is still relatively localized but as the species has established a reproductive population, it may eventually spread to other parts of the fjord and in time pose a problem to the oyster fishery. The species’ invasion history is reviewed

Spotlight on Charge-Transfer Excitons in Crystalline Textured n-Alkyl Anilino Squaraine Thin Films

Prototypical n-alkyl terminated anilino squaraines for photovoltaic applications show characteristic double-hump absorption features peaking in the green and deep-red spectral range. These signatures result from coupling of an intramolecular Frenkel exciton and an intermolecular charge transfer exciton. Crystalline, textured thin films suitable for polarized spectro-microscopy have been obtained for compounds with n-hexyl (nHSQ) and n-octyl (nOSQ) terminal alkyl chains. The here released triclinic crystal structure of nOSQ is similar to the known nHSQ crystal structure. Consequently, crystallites from both compounds show equal pronounced linear dichroism with two distinct polarization directions. The difference in polarization angle between the two absorbance maxima cannot be derived by spatial considerations from the crystal structure alone but requires theoretical modeling. Using an essential state model, the observed polarization behavior was discovered to depend on the relative contributions of the intramolecular Frenkel exciton and the intermolecular charge transfer exciton to the total transition dipole moment. For both nHSQ and nOSQ, the contribution of the charge transfer exciton to the total transition dipole moment was found to be small compared to the intramolecular Frenkel exciton. Therefore, the net transition dipole moment is largely determined by the intramolecular component resulting in a relatively small mutual difference between the polarization angles. Ultimately, the molecular alignment within the micro-textured crystallites can be deduced and, with that, the excited state transitions can be spotted.Comment: 12 pages, 8 figure

Dynamic complex-to-complex transformations of heterobimetallic systems influence the cage structure or spin state of iron(II) ions

Two new heterobimetallic cages, atrigonal-bipyr-amidal and acubic one, were assembled from the same mononuclear metalloligand by adopting the molecular library approach,using iron(II) and palladium(II) building blocks. The ligand system was designed to readily assemble through subcomponent self-assembly. It allowed the introduction of steric strain at the iron(II) centres, which stabilizes its para-magnetic high-spin state.This steric strain was utilized to drive dynamic complex-to-complex transformations with both the metalloligand and heterobimetallic cages. Addition of steri-cally less crowded subcomponents as achemical stimulus transformed all complexes to their previously reported low-spin analogues.The metalloligand and bipyramid incorporated the new building blockmore readily than the cubic cage, probably because the geometric structure of the sterically crowded metalloligand favours the cube formation. Further-more it was possible to provokestructural transformations upon addition of more favourable chelating ligands,converting the cubic structures into bipyramidal ones

A family of heterobimetallic cubes shows spin-crossover behaviour near room temperature

Using 4-(4′-pyridyl)aniline as a simple organic building block in combination with three different aldehyde components together with metal(II) salts gave three different Fe8Pt6-cubes and their corresponding Zn8Pt6 analogues by employing the subcomponent self-assembly approach. Whereas the use of zinc(II) salts gave rise to diamagnetic cages, iron(II) salts yielded metallosupramolecular cages that show spin-crossover behaviour in solution. The spin-transition temperature T1/2 depends on the incorporated aldehyde component, giving a construction kit for the deliberate synthesis of spin-crossover compounds with tailored transition properties. Incorporation of 4-thiazolecarbaldehyde or N-methyl-2-imidazole-carbaldehyde yielded cages that undergo spin-crossover around room temperature whereas the cage obtained using 1H-4-imidazolecarbaldehyde shows a spin-transition at low temperatures. Three new structures were characterized by synchrotron X-ray diffraction and all structures were characterized by mass spectrometry, NMR and UV/Vis spectroscopy

Projective dynamics and classical gravitation

Given a real vector space V of finite dimension, together with a particular homogeneous field of bivectors that we call a "field of projective forces", we define a law of dynamics such that the position of the particle is a "ray" i.e. a half-line drawn from the origin of V. The impulsion is a bivector whose support is a 2-plane containing the ray. Throwing the particle with a given initial impulsion defines a projective trajectory. It is a curve in the space of rays S(V), together with an impulsion attached to each ray. In the simplest example where the force is identically zero, the curve is a straight line and the impulsion a constant bivector. A striking feature of projective dynamics appears: the trajectories are not parameterized. Among the projective force fields corresponding to a central force, the one defining the Kepler problem is simpler than those corresponding to other homogeneities. Here the thrown ray describes a quadratic cone whose section by a hyperplane corresponds to a Keplerian conic. An original point of view on the hidden symmetries of the Kepler problem emerges, and clarifies some remarks due to Halphen and Appell. We also get the unexpected conclusion that there exists a notion of divergence-free field of projective forces if and only if dim V=4. No metric is involved in the axioms of projective dynamics.Comment: 20 pages, 4 figure

A Cauchy-Dirac delta function

The Dirac delta function has solid roots in 19th century work in Fourier analysis and singular integrals by Cauchy and others, anticipating Dirac's discovery by over a century, and illuminating the nature of Cauchy's infinitesimals and his infinitesimal definition of delta.Comment: 24 pages, 2 figures; Foundations of Science, 201

Flexible Meta-Regression to Assess the Shape of the Benzene–Leukemia Exposure–Response Curve

Ba c k g r o u n d: Previous evaluations of the shape of the benzene–leukemia exposure–response curve (ERC) were based on a single set or on small sets of human occupational studies. Integrating evidence from all available studies that are of sufficient quality combined with flexible meta-regression models is likely to provide better insight into the functional relation between benzene exposure and risk of leukemia. Objectives: We used natural splines in a flexible meta-regression method to assess the shape of the benzene–leukemia ERC. Met h o d s: We fitted meta-regression models to 30 aggregated risk estimates extracted from nine human observational studies and performed sensitivity analyses to assess the impact of a priori assessed study characteristics on the predicted ERC. Re s u l t s: The natural spline showed a supralinear shape at cumulative exposures less than 100 ppmyears, although this model fitted the data only marginally better than a linear model (p = 0.06). Stratification based on study design and jackknifing indicated that the cohort studies had a considerable impact on the shape of the ERC at high exposure levels (&gt; 100 ppm-years) but that predicted risks for the low exposure range (&lt; 50 ppm-years) were robust. Co n c l u s i o n s: Although limited by the small number of studies and the large heterogeneity between studies, the inclusion of all studies of sufficient quality combined with a flexible meta-regression method provides the most comprehensive evaluation of the benzene–leukemia ERC to date. The natural spline based on all data indicates a significantly increased risk of leukemia [relative risk (RR) = 1.14; 95 % confidence interval (CI), 1.04–1.26] at an exposure level as low as 10 ppm-years. Key w o r d s: benzene, epidemiology, leukemia, meta-regression, quantitative risk assessment. Environ Health Perspect 118:526–532 (2010). doi:10.1289/ehp.0901127 available vi

Ten Misconceptions from the History of Analysis and Their Debunking

The widespread idea that infinitesimals were "eliminated" by the "great triumvirate" of Cantor, Dedekind, and Weierstrass is refuted by an uninterrupted chain of work on infinitesimal-enriched number systems. The elimination claim is an oversimplification created by triumvirate followers, who tend to view the history of analysis as a pre-ordained march toward the radiant future of Weierstrassian epsilontics. In the present text, we document distortions of the history of analysis stemming from the triumvirate ideology of ontological minimalism, which identified the continuum with a single number system. Such anachronistic distortions characterize the received interpretation of Stevin, Leibniz, d'Alembert, Cauchy, and others.Comment: 46 pages, 4 figures; Foundations of Science (2012). arXiv admin note: text overlap with arXiv:1108.2885 and arXiv:1110.545

Associations between the urban exposome and type 2 diabetes: Results from penalised regression by least absolute shrinkage and selection operator and random forest models

BACKGROUND: Type 2 diabetes (T2D) is thought to be influenced by environmental stressors such as air pollution and noise. Although environmental factors are interrelated, studies considering the exposome are lacking. We simultaneously assessed a variety of exposures in their association with prevalent T2D by applying penalised regression Least Absolute Shrinkage and Selection Operator (LASSO), Random Forest (RF), and Artificial Neural Networks (ANN) approaches. We contrasted the findings with single-exposure models including consistently associated risk factors reported by previous studies. METHODS: Baseline data (n = 14,829) of the Occupational and Environmental Health Cohort study (AMIGO) were enriched with 85 exposome factors (air pollution, noise, built environment, neighbourhood socio-economic factors etc.) using the home addresses of participants. Questionnaires were used to identify participants with T2D (n = 676(4.6 %)). Models in all applied statistical approaches were adjusted for individual-level socio-demographic variables. RESULTS: Lower average home values, higher share of non-Western immigrants and higher surface temperatures were related to higher risk of T2D in the multivariable models (LASSO, RF). Selected variables differed between the two multi-variable approaches, especially for weaker predictors. Some established risk factors (air pollutants) appeared in univariate analysis but were not among the most important factors in multivariable analysis. Other established factors (green space) did not appear in univariate, but appeared in multivariable analysis (RF). Average estimates of the prediction error (logLoss) from nested cross-validation showed that the LASSO outperformed both RF and ANN approaches. CONCLUSIONS: Neighbourhood socio-economic and socio-demographic characteristics and surface temperature were consistently associated with the risk of T2D. For other physical-chemical factors associations differed per analytical approach