The association study of antioxidant status and antioxidant genes polymorphisms in patients with ischemic heart disease in the Republic of Tatarstan

Ischemic heart disease (IHD) is a multifactorial disease caused by the interplay of environmental risk factors with multiple predisposing genes. The present study was undertaken to evaluate the role of genetic polymorphism, oxidative stress and antioxidant status in IHD patients. IHD patients are characterized by a change of the blood serum's antioxidant status, which is expressed in significant increases/decreases of the total antioxidant activity, lipid hydroperoxides and ceruloplasmin indicators in comparison with normal values and also in significant increases of the malondialdehyde for the patients with acute myocardial infarction. This study also showed that the level of some of the examined antioxidant system indicators depends on polymorphism of the genes, which encode the enzymatic antioxidant system pool (genes of catalase, extracellular and mitochondrial superoxide dismutase and glutathione peroxidase). © IDOSI Publications, 2013

Comparative analysis of ascorbic acid content in the gruels for young children

The article compares the content of vitamin C in different cereals used for complementary foods for young children, prepared on different types of water and reconstituted infant formula for feeding children from 6 months. During the study, it was found that buckwheat and oatmeal are the richest in ascorbic acid, cooked in special children's waters or reconstituted dairy formula. Recommendations are given to improve complementary foodsВ статье сравнивается содержание витамина С в разных кашах, используемых для прикорма детей раннего возраста, приготовленных на различных типах вод и восстановленной молочной смеси для питания детей с 6 месяцев. В ходе исследования было установлено, что наиболее богаты аскорбиновой кислотой гречневая и овсяная каша, приготовленные на специальных детских водах или восстановленной молочной смеси. Даются рекомендации для улучшения прикорм

ON THE PROBLEM OF CAREER COUNSELING FOR UNIVERSITY GRADUATES

The article discusses the problems of career counseling for university graduates. The experience of Europe and Russia in the development of innovations in the field of career guidance and counseling is presented. The classes are based on a reflexive process that allows you to realize yourself as a professional, to design different lines of your career development. The implementation of the proposed course is aimed at understanding the importance of the problem of secondary professional self-determination, expanding the perception of their professional opportunities for the student.В статье обсуждаются проблемы карьерного консультирования выпускников вузов. Приведен опыт Европы и России по развитию инноваций в сфере профориентации и консультирования. В основе занятий — рефлексивный процесс, который позволяет осознать себя профессионалом, конструировать разные линии своего карьерного развития. Реализация предложенного курса направлена на осознание важности проблемы вторичного профессионального самоопределения, расширение восприятие своих профессиональных возможностей для студента

Quality expertise of dispensary observation of disabled children suffering from type 1 of diabet

The purpose of the study is to analyze the quality of dispensary observation of disabled children with type 1 diabetes, identify disadvantages and offer corrective measures.Цель исследования – провести анализ качества диспансерного наблюдения детей-инвалидов с сахарным диабетом 1 типа, выявить недостатки и предложить корректирующие мероприятия

Intrapulmonary lymph nodes: morphology, diagnostics,clinical significance

A review of the literature on the problem of morphology of intrapulmonary lymph nodes (IPLN), their importance in clinical and radiological practice presents in the article. The urgency of the problem of IPLN become significant with the advent of high resolution computed tomography (HRCT) scan, which allows to detect pulmonary masses less than 0.5 cm in size. The articles devoted to the morphology of intrapulmonary lymph nodes in russian literature are sporadic. The issues of embryogenesis and histogenesis, function of these anatomical structures are unresolvedв and require further research.В статье представлен обзор литературных данных, раскрывающий вопросы морфологии внутрилегочных лимфатических узлов (ВЛЛУ) их значение в клинической и рентгенологической практике. Актуальность проблемы ВЛЛУ приобрела особое значение с появлением компьютерной томографии высокого разрешения, которая позволяет определять образования в легких размером менее 5 мм. В отечественной литературе работы, посвященные морфологии внутрилегочных лимфатических узлов, единичны. Вопросы эмбрио- и гистогенеза, функциональное значение этих анатомических образований остаются открытыми и требуют дальнейшего изучения

Studying irritating and sensitizing effect on laboratory animals of pharmacologically active composition

The article presents the results of an experiment in which studied the effect of the pharmaceutical active composition (PAC) SEV-14-891, containing 0,6% lactic acid, siliceous chitosan containing glycerohydrogel - else up to 100%, as well as a possible local irritating and sensitizing effect on the skin and mucous membranes of the eyes of rabbits.В статье представлены результаты эксперимента, в ходе которого исследовалось влияние фармакологически активной композиции (ФАК) SEV-14-891, содержащей молочную кислоту 0,6%, кремнийхитозансодержащий глицерогидрогель – остальное до 100%, на возможное сенсибилизирующее и местно-раздражающее действия на кожный покров и слизистую глаз кролико

Polymorphism of thrombophilia genes in children with stage V CKD

The article presents the results of a study of genetic polymorphisms associated with the risk of thrombophilia in children aged 1 to 17 years who were hospitalized in the department of nephrology of the Regional children's clinical hospital (Yekaterinburg) in 2020 with chronic kidney disease stage 5 (CKD Stage 5) for hemodialysisВ статье представлены результаты исследования генетических полиморфизмов, ассоциированных с риском тромбофилии, у детей от 1 года до 17 лет, госпитализированных в отделение нефрологии ГАУЗ СО «Областная детская клиническая больница» (г. Екатеринбург) в 2020 году с хронической болезнью почек 5 стадии (ХБП 5 стадии) для проведения гемодиализ

Inventory of current EU paediatric vision and hearing screening programmes

Background: We examined the diversity in paediatric vision and hearing screening programmes in Europe. Methods: Themes relevant for comparison of screening programmes were derived from literature and used to compile three questionnaires on vision, hearing and public-health screening. Tests used, professions involved, age and frequency of testing seem to influence sensitivity, specificity and costs most. Questionnaires were sent to ophthalmologists, orthoptists, otolaryngologists and audiologists involved in paediatric screening in all EU fullmember, candidate and associate states. Answers were cross-checked. Results: Thirty-nine countries participated; 35 have a vision screening programme, 33 a nation-wide neonatal hearing screening programme. Visual acuity (VA) is measured in 35 countries, in 71% more than once. First measurement of VA varies from three to seven years of age, but is usually before the age of five. At age three and four picture charts, including Lea Hyvarinen are used most, in children over four Tumbling-E and Snellen. As first hearing screening test otoacoustic emission (OAE) is used most in healthy neonates, and auditory brainstem response (ABR) in premature newborns. The majority of hearing testing programmes are staged; children are referred after one to four abnormal tests. Vision screening is performed mostly by paediatricians, ophthalmologists or nurses. Funding is mostly by health insurance or state. Coverage was reported as >95% in half of countries, but reporting was often not first-hand. Conclusion: Largest differences were found in VA charts used (12), professions involved in vision screening (10), number of hearing screening tests before referral (1-4) and funding sources (8)

The association study of antioxidant status and antioxidant genes polymorphisms in patients with ischemic heart disease in the Republic of Tatarstan

Ischemic heart disease (IHD) is a multifactorial disease caused by the interplay of environmental risk factors with multiple predisposing genes. The present study was undertaken to evaluate the role of genetic polymorphism, oxidative stress and antioxidant status in IHD patients. IHD patients are characterized by a change of the blood serum's antioxidant status, which is expressed in significant increases/decreases of the total antioxidant activity, lipid hydroperoxides and ceruloplasmin indicators in comparison with normal values and also in significant increases of the malondialdehyde for the patients with acute myocardial infarction. This study also showed that the level of some of the examined antioxidant system indicators depends on polymorphism of the genes, which encode the enzymatic antioxidant system pool (genes of catalase, extracellular and mitochondrial superoxide dismutase and glutathione peroxidase). © IDOSI Publications, 2013

The association study of antioxidant status and antioxidant genes polymorphisms in patients with ischemic heart disease in the Republic of Tatarstan

Ischemic heart disease (IHD) is a multifactorial disease caused by the interplay of environmental risk factors with multiple predisposing genes. The present study was undertaken to evaluate the role of genetic polymorphism, oxidative stress and antioxidant status in IHD patients. IHD patients are characterized by a change of the blood serum's antioxidant status, which is expressed in significant increases/decreases of the total antioxidant activity, lipid hydroperoxides and ceruloplasmin indicators in comparison with normal values and also in significant increases of the malondialdehyde for the patients with acute myocardial infarction. This study also showed that the level of some of the examined antioxidant system indicators depends on polymorphism of the genes, which encode the enzymatic antioxidant system pool (genes of catalase, extracellular and mitochondrial superoxide dismutase and glutathione peroxidase). © IDOSI Publications, 2013