194 research outputs found
Traffic based energy consumption optimisation to improve the lifetime and performance of ad hoc wireless sensor networks
Ad hoc wireless sensor networks (WSNs) are formed from self-organising configurations of distributed, energy constrained, autonomous sensor nodes. The service lifetime of such sensor nodes depends on the power supply and the energy consumption, which is typically dominated by the communication subsystem. One of the key challenges in unlocking the potential of such data gathering sensor networks is conserving energy so as to maximize their post deployment active lifetime. This thesis described the research carried on the continual development of the novel energy efficient Optimised grids algorithm that increases the WSNs lifetime and improves on the QoS parameters yielding higher throughput, lower latency and jitter for next generation of WSNs. Based on the range and traffic relationship the novel Optimised grids algorithm provides a robust traffic dependent energy efficient grid size that minimises the cluster head energy consumption in each grid and balances the energy use throughout the network. Efficient spatial reusability allows the novel Optimised grids algorithm improves on network QoS parameters. The most important advantage of this model is that it can be applied to all one and two dimensional traffic scenarios where the traffic load may fluctuate due to sensor activities. During traffic fluctuations the novel Optimised grids algorithm can be used to re-optimise the wireless sensor network to bring further benefits in energy reduction and improvement in QoS parameters. As the idle energy becomes dominant at lower traffic loads, the new Sleep Optimised grids model incorporates the sleep energy and idle energy duty cycles that can be implemented to achieve further network lifetime gains in all wireless sensor network models. Another key advantage of the novel Optimised grids algorithm is that it can be implemented with existing energy saving protocols like GAF, LEACH, SMAC and TMAC to further enhance the network lifetimes and improve on QoS parameters. The novel Optimised grids algorithm does not interfere with these protocols, but creates an overlay to optimise the grids sizes and hence transmission range of wireless sensor nodes
ON PERFORMANCE OF QUANTUM LOCKING FOR WHEEL-LESS TRANSPORTATION
Transportation has continuously been a vital side of human civilization reflective the extent of general economic and technological advancement of a given society. The recent technological advancements in power electronics are pushing for Maglev train using Quantum locking. For levitation the most important factor is temperature which is affecting the efficiency of the train. In this work we have compared different prototypes of Maglev trains including Japanese, German and Chinese technologies. We also did mathematical modeling to relate the magnetic force required for a certain weight of the train to levitate. We suggest that Japanese maglev is better than Germany and china maglev
Total Quality Management A Recommended Strategy For The Pakistani Banking Sector
Keeping in view the significance of TQM in todays competitive banking environment, the study was designed to look into the quality implementation level of commercial banks in Pakistan. Main offices of all commercial banks operating in Pakistan were contacted and were asked about the level of implementation of TQM in their bank; whether the quality implementation is at its introductory, middle, final or fully implemented stage. The data indicated that majority of the banks in Pakistan are at the introductory stage where as almost one fifth claim having TQM fully implemented. The situation highlights the level of effort put by management of banks operating in Pakistan and initiatives taken by them in respect of quality management. The findings of the study may be passed on to Central Bank for further necessary action and follow up
ON PERFORMANCE OF QUANTUM LOCKING FOR WHEEL-LESS TRANSPORTATION
Transportation has continuously been a vital side of human civilization reflective the extent of general economic and technological advancement of a given society. The recent technological advancements in power electronics are pushing for Maglev train using Quantum locking. For levitation the most important factor is temperature which is affecting the efficiency of the train. In this work we have compared different prototypes of Maglev trains including Japanese, German and Chinese technologies. We also did mathematical modeling to relate the magnetic force required for a certain weight of the train to levitate. We suggest that Japanese maglev is better than Germany and china maglev
Foregrounding through Lexical Deviation: A Corpus-Based Analysis of Yousafi’s Aab-e-Gum
This paper provides a corpus-based analysis of lexical deviation as a foregrounding technique in Yousafi’s prose fiction Aab-e-Gum. The use of unusual and uncommon language imparts a strong impression on the readers’ minds. This distinguished use of language diverges from the literary conventions maintaining a dominant structure in a text (Leech, 1969) and is known as deviation. The theoretical and conceptual grounds for this work are Ross' (1998) structural incongruity theory and Leech and Short's (2007) conceptions of deviation in literary texts. The corpus for this research is the Urdu text Aab-e-Gum. The data is tagged using the UAM Corpus tool (UAMCT3). The system is used to manually tag all occurrences of deviation across various linguistic levels and sub-levels in the first stage. The more frequent lexical divergence is investigated in the second stage. It is discovered that the author used lexical variation as a foregrounding strategy to create novel Urdu terms. His use of lexical variation serves to both heighten the event being portrayed and to entertain the audience. Future work on different linguistic levels can be done in depth. This study is a first step in assisting linguistic researchers working on the Urdu language
Handling temporal constraints in interaction protocols for intelligent multi-agent systems
This research focuses on handling temporal constraints in interaction protocols for multi-agent systems. There is a dire need of standardized interaction protocols that can be used to handle timing aspects in real-time multi-agent system’s negotiation. The most commonly used Foundation for Intelligent Physical Agents Protocol lacks the appropriate specification in this regard. In real-time systems timing constraint is a major concern for all of its tasks and goals. Agents require real-time responses and must eliminate the possibility of massive communication between them. The timing specification of these real-time multi-agent systems in which agents communicate with each other to achieve their goals within deadline will be of great value for their correct functioning. A high degree of dependability and predictability is expected from real-time software agents. The basis of our work is the standardized interaction protocols to support the communication between agents in real-time environment and this is possible via message passing. By incorporation of well-defined timing parameters in Foundation for Intelligent Physical Agents performatives, we have enabled them to be used in any real-time multi-agent’s communication. We demonstrate the usage and effectiveness of our proposed real-time performatives using a case study of monitoring boats in marine reserves in which the agents interact with each other to accomplish their goals
Virulence profiling of Shigella flexneri and emergence of serotype 2b as a highly virulent shigellosis causing strain in Pakistan
Bacillary diarrhea caused by Shigella flexneri is mediated by various virulence factors which make it the leading agent of diarrhea in developing countries. Previously, a high prevalence of S. flexneri, associated with diarrhea has been reported in Pakistan but no data is available on their virulence profile. The present study reporting for the first time analysis of various virulence factors among S. flexneri serotypes isolated from clinical (diarrheal stool) and non-clinical (retail raw foods and drinking water) sources. A total of 199 S. flexneri (clinical: 155, raw foods: 22, water: 22) belonging to various serotypes were subjected to virulence genes detection and virulence profiling. The most frequent virulence gene was found to be ipaH (100%), followed by sat (98%), ial (71.3%), set1B (65.8%) and set1A (38.7%). A high level of virulence was detected in serotype 2b as compared to other serotypes as 32.3% of all serotype 2b have the entire set of five virulence genes including ipaH (100%), ial (100%), sat (37.7%), set1A (89.3%), and set1B (100%). Seven different virulence gene profiles (V1 - V7) were detected and the most frequently observed to be V1 (ipaH+, ial+, sat+, set1A+, set1B+) followed by V3 (ipaH+, ial+, sat+, set1B+). The predominant virulence gene pattern in serotype 2b isolated from clinical and non-clinical samples were V1 and V3. Furthermore, about 32% strains belongs to serotype 2b contain the complete set of five virulence genes isolated from patients with high disease severity. In conclusion, the current finding revealed for the first times that serotype 2b was the most virulent strains in both clinical and non-clinical samples in Pakistan. In addition, the virulence of serotype 2b was well correlated with high disease severity
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Ibuprofen Nanoparticles and its cytotoxicity on A549 and HaCaT cell lines
yesIbuprofen (IBF) is an outstanding non-steroidal drug for analgesic and anti-inflammatory therapies but
it exhibits poor solubility in water [1, 2]. Increased dosage administration has been linked to gastrointestinal and
cardiovascular complications [3]. Many techniques have been employed to improve the solubility of NSAIDs [4]. In this
study, the anti-solvent precipitation method was used to make Ibuprofen nanoparticles (IBF NPs). Optimised
preparation parameters such as solvent (ethanol), raw drug concentration (400 mg), solvent/anti-solvent ratio (1:50)
and surfactant concentration (0.25 mg/ml) have been studied to yield nanoparticles with a mean size of 58.8 nm,
which is confirmed by dynamic light scattering and transmission electron microscopy. These IBF NPs posess
increased aqueous solubility compared to the micro counterpart and maintain with chemical integrity indicated by high
performance liquid chromatography and Fourier transform infrared spectroscopy.
In addition, in vitro cytotoxicity of IBF NPs has been studied on A549 and HaCat cell lines using MTT and LDH
assays. Both cells were obtained from ATCC. The A549 cells were grown in a modification of Ham’s F-12, containing
L-glutamine, called F-12K. The HaCaT cells were grown in DMEM containing sodium pyruvate (110 mg/l). Normal cell
culture and sub-culture were applied and the cells were used after around 45 passages [5]. The cell culture media
containing 105cells/ml were placed in a 96-well plate with addition of IBF NPs and Micro form at concentrations in the
range of between 6 and 500 ug/ml by diluting them with DMEM and F-12K for use with the HaCaT and A549 cells
respectively. After 24, 48 and 72h exposure, the MTT and LDH cytotoxicity assay were performed in triplicates and on
three separate experiment cultures and the absorbance was recorded at 570 nm and 492nm respectively with Elisa
micro plate reader. The cell viability (%) related to control (cells in culture medium without NPs) was calculated. A very good cytotoxicity profile was observed, indicating an in vitro cytocompatibility of the IBF NPs in these cell culture
systems and no significant changes in cytotoxicity compared with Micro IBF.
We conclude that our IBF NPs have increased solubility, same chemical integrity and unchanged cytotoxicity
compared to IBF Micro drug. Further work will concentrate on optimising more rigorous parameter to produce
excellent quality NPs. More detailed characterisation of IBF NPs is to be tested, such as using PXRD and SEM to
further corroborate particle shape and size. The range of no toxic in vitro concentrations is also to be further
confirmed. Eventually scaled up preparation of IBF NPs will be developed without relinquishing NPs quality. This
would improve the potential for in vitro/ in vivo applications and clinical use of IBF NPs and NSAIDs in general
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