The Number of Lymphocyte and Monosit due to Hypoxic Hypoxia

Oxygen have an important role in body metabolism.  Lack of oxygen can caused uncomplete metabolism. There will be increasing consumtion of glucose in anaerob metabolism. Hypoxia can stimulate the circulatory system and hematology to improve oxygenation function. This research purpose to knows effect of hypoxic hypoxia duration to the lymphocytes and monocytes on Rattus norvegicus. This is experimental research, pre and post control group design. Hypoxia condition made from modification of hypoxia chamber with 10% oxygen level from total volume of chamber. Subject is male of Rattus norvegicus 2 month’s old weight 150 – 200 grams. Measuring of lymphocytes and monocytes used manual hemocytometer and the hemoglobin use spektrofotometer. Data analysis used t-test and oneway anova CI 95 %. Results of analysis with Oneway-ANOVA statistical test showed there was no difference in the number of lymphocytes were statistically significant in the fourth study group after treatment (p = 0.31). Similarly Oneway-ANOVA statistical test showed there was no difference in the number of lymphocytes were statistically significant in all four study group after treatment (p = 0.99). The number of lymphocytes and monocytes increased due to hypoxic hypoxia although not statistically significant. Increasing the number of lymphocytes highest in the group induced hypoxic hypoxia 36 hours and the number of monocytes highest in the group induced hypoxic hypoxia 12 hours. Keywords : lymphocytes, monocytes, hypoxia, oxygen

Hubungan Konsumsi Makanan Cepat Saji dan Tingkat Aktivitas Fisik terhadap Obesitas pada Kelompok Usia 11-13 Tahun

Obesity is a chronic condition characterized by an excess of body fat. Obesity in adolescence also cause a problem for social life and emotional. Food habit in adolescent is significantly influenced by their life style, including the consumption of fast food. This research was aimed to know whether consumption of fast food and physical activity is a risk factor of obesity in adolescent. This research was observed with cross-sectional design. Subject were students of SLTP, aged 11-13 year old samples for obesity were obtained by random sampling. The data of obesity prevalence were calculate based on the number of obesity students. The correlation of fast food consumption and physical activity with obesity was analyzed with regression and correlation analysis. There was no significant correlation between the amount of fast food and fast food consumption frequency and obesity (p 0.05), while the level of physical activity has a significant correlation with obesity (p0.05). The contribution of fast-food consumption does not increase the risk of obesity and the higher level of physical activity, the lower the risk of obesity.Obesitas merupakan kondisi kronis dengan karakteristik kelebihan lemak tubuh. Obesitas pada remaja juga menyebabkan masalah bagi kehidupan sosial dan emosi yang cukup berarti. Kebiasaan makan pada remaja dipengaruhi secara signifikan oleh perubahan gaya hidup mereka, temasuk mengkonsumsi makanan cepat saji. Penelitian ini bertujuan mengetahui apakah konsumsi fast food dan tingkat aktivitas fisik merupakan faktor risiko terjadinya obesitas pada remaja. Penelitian ini bersifat observasional dengan menggunakan rancangan cross-sectional. Populasi dan sampel adalah remaja SLTP dengan usia 11-13 tahun, dengan pengambilan sampel untuk penjaringan obesitas secara random sampling. Analisis untuk mengetahui hubungan konsumsifast food dan tingkat aktivitas fisik terhadap obesitas dilakukan dengan menggunakan regresi dan korelasi. Tidak ada hubungan yang bermakna antara banyaknyajenisfast food dan frekuensi konsumsi fast food terhadap obesitas (p0,05) sedangkan tingkat aktivitas fisik memiliki hubungan bermakna dengan obesitas (p0,05). Kontribusi konsumsi fast food tidak meningkatkan resiko terjadinya obesitas. Semakin tinggi tingkat aktivitas fisik, semakin rendah resiko terjadinya obesitas

UPAYA PENCEGAHAN DIABETES MELLITUS MELALUI PROMOSI KESEHATAN DI ERA COVID-19

Abstrak: Pengabdian masyarakat ini bertujuan untuk menambah pengetahuan, kesadaran dan kewaspadaan tentang diabetes melitus, faktor-faktor risiko, pengendalian serta komplikasi DM. Sasaran program pengabdian ini adalah 17 kader kesehatan  di desa Tamantirto, Kasihan, Bantul, Yogyakarta.  Pelaksanaan pengabdian masyarakat ini berlangsung di masa pandemi COVID-19. Metode kegiatan pengabdian adalah promosi kesehatan diabetes melitus secara online melalui Zoom meeting. Hasil kegiatan pengabdian ini memperlihatkan bahwa sasaran kegiatan pengabdian antusia dan memberikan respon yang baik. Hasil evaluasi (pretest dan postest) kegiatan menunjukkan adanya peningkatan pengetahuan DM sebesar 25%. Promosi kesehatan DM di era COVID-19 secara online dengan media Zoom meeting dapat meningkatkan pengetahuan tentang diabetes dengan baik. Abstract: This community service aims to increase knowledge, awareness and vigilance about diabetes mellitus, risk factors, control and complications of diabetic. The target of this service program is 17 health cadres in Tamantirto, Kasihan, Bantul, Yogyakarta. The implementation of this community service took place during the COVID-19 pandemic. The method of community service activities is online diabetes mellitus health promotion through Zoom meetings. The results of this service activity show that the target of the service activity is enthusiastic and gives a good response. The results of the evaluation (pretest and posttest) of activities showed an increase in DM knowledge by 25%. DM health promotion in the COVID-19 era online with the Zoom meeting media can improve diabetic knowledge well

PROMOSI KESEHATAN KERJA PADA PENGRAJIN TENUN

ABSTRAKMasalah kesehatan kerja mempengaruhi individu, keluarga dan masyarakat. Pengabdian masyarakat ini bertujuan untuk menambah pengetahuan kesehatan kerja, dampak kerja terhadap kesehatan serta pencegahannya. Disamping itu juga untuk menambah wawasan para pekerja mengenai pentingnya penerapan budaya kesehatan dan keselamatan kerja (K3) di tempat kerja serta menciptakan kondisi tempat kerja yang aman dan nyaman bagi para pekerja. Metode pengabdian masyarakat menggunakan promosi dan edukasi kesehatan kerja. Sasaran program pengabdian masyarakat ini adalah 15 orang pengrajin  tenun Sejati Desa. Kegiatan pengabdian masyarakat ini meliputi : pembuatan media promosi kesehatan (leaflet); Edukasi dan promosi  kesehatan kerja; evaluasi kegiatan dengan tanya jawabHasil pengabdian masyarakat ini menunjukkan adanya tambahan pengetahuan pekerja tenun terkait kesehatan kerja. Promosi kesehatan kerja masih diperlukan untuk menambah pengetahuan kesehatan kerja. Kata kunci: kesehatan; kerja; pengetahuan; tenun ABSTRACTOccupational health problems affect individuals, families and communities. This community service aims to increase knowledge of occupational health, the impact of work on health and its prevention. Besides that, it is also to increase the knowledge of workers about the importance of implementing a culture of occupational health and safety (K3) in the workplace and creating safe and comfortable workplace conditions for workers. Community service methods use promotion and occupational health education. The target of this community service program is 15 Sejati Desa weaving craftsmen. These community service activities include: making health promotion media (leaflets); Occupational health education and promotion; evaluation of activities with discussion. The results of this community service show that weaving workers have additional knowledge regarding occupational health. Occupational health promotion is still needed to increase occupational health knowledge. Keywords: health; work; knowledge; weavin

Obesitas Hubungannya dengan Pola Asuh dan Tingkat Penghasilan Orang Tua pada Kelompok Usia 11-13 Tahun

Obesity has been a seriously problem in many developed country. The increase of obesity number and many risk factor that will faced the suffer cause the important of controlling obesity number early on. This research purpose is to know the correlation between parenting styles and degree of parents income in 11-13 years old. The research subjects are students 7th class of 11-13 years old in research time as many 114 respondents (46 respondents are obesity, 68 respondents are non-obesity). High and weight of respondents are measured to get IMT, then gave questioner for respondents and their parents. Statistic test done with lambda and coefficient correlation after data collected. The result of statistic test with lambda show that statistically no significant correlation (p0,05) between parenting style and obesity. The statistic test result with correlation show that no significant correlation between degree of family income with obesity statistically (p0,05). The result of this research is there are no correlation between parenting styles and degree of family income with obesityObesitas sudah menjadi masalah yang penting di berbagai negara maju. Semakin meningkatnya angka obesitas dan banyaknya faktor resiko yang akan dihadapi penderita menyebabkan pentingnya pengendalian angka obesitas sejak dini. Penelitian ini bertujuan untuk mengetahui hubungan antara pola asuh dan tingkat penghasilan orang tua pada kelompok usia 11¬13 tahun. Subjek penelitian ini adalah siswa kelas 7 SMP yang berusia 11-13 tahun pada saat penelitian berlangsung sebanyak 114 responden (46 responden yang obesitas, 68 responden yang tidak obesitas). Responden diukur tinggi dan berat badannya untuk mendapatkan IMT, kemudian diberikan kuesioner untuk responden dan orang tuanya. Setelah data dikumpulkan, dilakukan uji statistik dengan lambda dan coefficient correlation. Hasil uji statistik dengan lambda menunjukkan bahwa tidak ada hubungan yang bermakna secara statistik (p 0,05) antara pola asuh dan obesitas. Sedangkan hasil uji statistik dengan correlation menunjukkan bahwa tidak ada hubungan yang bermakna secara statistik (p 0,05) antara tingkat penghasilan orang tua dengan obesitas. Hasil Penelitian dapat memperlihatkan bahwa tidak ada hubungan yang bermakna antara pola asuh orang tua dan tingkat penghasilan dengan obesitas

Antidiabetic Activity of Banana Peel Extract : Effect on Hyperglycemia, Hyperlipidemia and Augmented Oxidative Stress in Diabetes Mellitus

Diabetes mellitus is one of the common metabolic disorders acquiring around 2.8% of the world's population and is anticipated to cross 5.4% by the year 2025. In 2012, the number of diabetes sufferers in Indonesia ranked as the seventh largest number of diabetics as many as 7.6 million and according to the WHO the prevalence of diabetes cases will continue to rise up to 154% in 2030. Since long back herbal medicines have been the highly esteemed source of medicine therefore, they have become a growing part of modern, high-tech medicine. From the review it was suggested that banana peel contained large amounts of dopamine and L-dopa, catecholamines with a significant antioxidant activity. The banana peel also shown the ability as antioxidants to prevent the oxidation of fish oil and might be considered as rich sources of natural antioxidant. Thus, from the review majorly, the antidiabetic activity of banana peel is attributed to the presence of pectin (10-21%), lignin (6-12%), cellulose (7,6- 9.6%), and hemicellulose (from 6.4 to 9.4%) which show reduction in blood glucose levels. Another research shown that pectin can also against hypercholesterolemia with decreasing total cholesterol, LDL cholesterol and HDL cholesterol. Keywords: Banana Peel Extract, Antidiabetic activity, Diabetes mellitus, Pecti

Relationship between Demographic Factors and Body Mass Index with the Prevention of Hypertension in Adolescents

Background: Hypertension or increased blood pressure is often referred as the silent killer because it usually does not show significant signs and symptoms. Thus, almost all patients do not realize if they suffer from hypertension. The Basic Health Research (Riskesdas) 2007 reported that the prevalence of hypertension in the population aged over 18 years old in Indonesia was 31.7%. Because of the increasing prevalence of hypertension in adolescence, it is necessary to take precautions. This study aimed to examine the relationship between demographic factors and body mass index with the prevention of hyper­tension in adolescentsSubjects and Method: This was a cross sec­tional study conducted at Muhammadiyah 1 Senior high school, Yogyakarta, from May 2017 to February 2018. A sample of 80 students was selected for this study. The dependent variables were prevention behavior. The independent variables were age, sex, body mass index (BMI), and residence. The data were collected by questionnaire and analyzed by Chi square.Results: 48 (60%) students had good hyper­tension prevention behavior. Female (OR= 3.00; p= 0.030), urban residence (OR= 2.78; p= 0.040), and normal body weight (OR= 4.30; p= 0.001) increased behavior of hypertension prevention, and they were statistically signi­ficant. Older age (OR= 1.59; p= 0.220) incre­ased behavior of hypertension preven­tion, but it was statistically non-significant.Conclusion: Female, urban residence, normal body weight, and older age increase behavior of hypertension prevention.Keywords: hypertension prevention behavior, demographic factorsCorrespondence: Ratna Indriawati. Department of Physiology, Faculty of Medicine and Health Sciences, Uni­versitas Muhammadiyah Yogyakarta, Yogya­karta 55183 Indonesia. Email: r_indriawati­[email protected] of Health Promotion and Behavior (2020), 5(2): 72-78https://doi.org/10.26911/thejhpb.2020.05.02.01 

HUBUNGAN USIA DAN JENIS KELAMIN DENGAN KEJADIAN KANKER DI RS PKU MUHAMMADIYAH YOGYAKARTA

Background: The global incidence of cancer has increased in the previous three years. According to WHO estimations from 2018, Indonesia is the 23rd nation in Asia with the largest number of cancer patients. Cancer is a disease in which aberrant cells spread uncontrollably and can result in death. Until today, the cause of cancer has remained unknown. A number of variables have been discovered to contribute to a rise in cancer prevalence. Age and gender are two of these variables. Purpose : The purpose of this research is to see if there is a link between age, gender and cancer incidence in the PKU Muhammadiyah Hospital in Yogyakarta. Method: The research is analytic and uses a cross-sectional method. The research included 142 cancer patients at PKU Muhammadiyah Hospital who were currently receiving therapy, and 105 samples were collected. The chi-square test was used to do bivariate analysis.Result:  The majority of cancer patients at PKU Muhammadiyah Yogayakarta Hospital were between the ages of 40 and 49. (50.5%). Female respondent, with a total of 67 persons, dominated the number of cancer patients (63.8 percent).Conclusion:  There is a correlation between gender and age with the incidence of cancer at PKU Muhammadiyah Hospital Yogyakart

Pengaruh Lama Hipoksia terhadap Angka Eritrosit dan Kadar Hemoglobin Rattus norvegicus

Oksigen berperan penting dalam proses metabolisme tubuh. Kekurangan oksigen menyebabkan metabolisme berlangsung tidak sempurna. Hipoksia merangsang sistem hematologi dan sirkulasi untuk meningkatkan fungsi oksigenasi. Penelitian ini bertujuan untuk mengkaji pengaruh lama hipoksia terhadap angka eritrosit dan kadar hemoglobin Rattus norvegicus. Penelitian ini merupakan penelitian eksperimental, pre and post control group design. Perlakuan hipoksia menggunakan modifikasi hypoxia chamber dengan pemberian kadar oksigen sebesar 10% dari total volume kandang. Pengukuran eritrosit menggunakan manual haemositometer dan hemoglobin menggunakan spektrofotometer. Analisis data menggunakan uji T test dan oneway anova, Kruskall Wallis dengan tingkat kepercayaan 95%. Hasil rerata ± SD hemoglobin (gr/dl) dari seluruh kelompok kontrol, 12, 24 dan 36 jam hipoksia sebelum dan sesudah secara berturut-turut yakni 10,89 ± 0,755 dan 8,74 ± 0,762. Hasil rerata ± SD eritrosit (juta/¼l) seluruh kelompok kontrol, 12, 24 dan 36 jam sebelum dan sesudah yakni 5,63 ± 0,74 dan 4,19 ± 0,523. Hasil Uji T-test hemoglobin dari kelompok kontrol, 12, 24 dan 36 jam hipoksia secara berturut-turut dengan nilai  p = 0,227, p = 0,492, p = 0,000, p = 0,000 dan hasil uji T-test eritrosit dari kelompok kontrol, 12, 24, 36 jam hipoksia secara berturut-turut dengan nilai p = 0,004, p = 0,243, p = 0,001, p = 0,003. Hasil oneway anova kadar hb (p = 0,000)  dan hasil Kruskall Wallis angka eritrosit (p = 0,018). Disimpulkan bahwa terjadi peningkatan angka eritrosit dan kadar hemoglobin pada perlakuan 12 jam dan penurunan pada perlakuan 24 dan 36 jam hipoksia pada Rattus norvegicus. Oxygen have an important role in body metabolism. Lack of oxygen caused uncomplete metabolism. Hypoxia can stimulate the circulatory system and hematology to improve oxygenation function. This research purpose to knows effect of hypoxia duration to the erythrocyte and hemoglobin on Rattus norvegicus. This is experimental research, pre and post control group design. Hypoxia condition made from modification of hypoxia chamber with 10% oxygen level from total volume of chamber. Measuring of erythrocyte used manual hemocytometer and the hemoglobin use spektrofotometer. Data analysis used T test and oneway anova, Kruskall Wallis with CI 95 %. The result from all of group control, 12, 24 and 36 hour pre and post hemoglobin median ± SD (gr/dl) were 10,89 ± 0,755 and 8,74 ± 0 ,762 and median ± SD of erythrocyte (106/ ¼l) were 5,63 ± 0,74 and 4,19 ± 0,523. The result T test showed the correlation of pre and post hemoglobin from control, 12, 24, and 36 hour duration hypoxia were p = 0,227, p = 0,492, p = 0,000, p = 0,000 and the erythrocyte from control, 12, 24, and 36 hour duration hypoxia were p = 0,004 , p =  0,243, p = 0,001, p = 0,003. Result from Oneway anova from haemoglobin (p = 0,000) and result of Kruskall Wallis from erythrocyte (p = 0,018). It can concluded that there is increasing erythrocyte and hemoglobin on 12 hour and decreasing on 24 and 36 hour hypoxia on Rattus norvegicus