2 research outputs found
Seroprevalence of HBV among people living with HIV in Anyigba, Kogi State, Nigeria
Background: Co-infection of HBV with HIV is associated with significant morbidity and mortality globally. In spite of increasing reports of HIV/HBV co-morbidities in Nigeria, little or no data exists on this subject in Anyigba. Therefore,we determined the prevalence of hepatitis B surface antigenemia among HIV positive patients on anti-retroviral treatment programme in Anyigba, Kogi State, North-Central Nigeria.Methods: Sera samples obtained from 200 consented HIV patients were screened for HBsAg using the commercial rapid test membrane-based qualitative immunoassay. A structured questionnaire was used to collect information on patients’ demographic variables and probable risk factors for HBV transmission.Results: Overall, 3.5% of HIV patients were seropositive to HBsAg and the difference between seroprevalence rates and patients’ age as well as gender was not statistically significant (p>0.05). There was significant difference between patients’ demographicvariables such as marital status (p=0.013) and educational level (p=0.004) and HBsAg seropositivity. Patients with a history of surgical applications (p=0.01) and who indulged in alcoholism (p=0.03) significantly had higher rates of concomitant HIV/HBV infection in the study area.Conclusion: Our findings underscore the importance of routine screening for HBV in the HIV infected populations especially in developing countries where the infection is endemic. We advocate for public enlightenment programmes on routes of virus acquisitions with a view to reduce the morbidity and mortality associated HIV/HBV co-infection.Keywords: HBV, HIV, co-infection, risk factors, Nigeria
Seroprevalence of HBV among people living with HIV in Anyigba, Kogi State, Nigeria
Background: Co-infection of HBV with HIV is associated with significant
morbidity and mortality globally. In spite of increasing reports of
HIV/HBV co-morbidities in Nigeria, little or no data exists on this
subject in Anyigba. Therefore,we determined the prevalence of hepatitis
B surface antigenemia among HIV positive patients on anti-retroviral
treatment programme in Anyigba, Kogi State, North-Central Nigeria.
Methods: Sera samples obtained from 200 consented HIV patients were
screened for HBsAg using the commercial rapid test membrane-based
qualitative immunoassay. A structured questionnaire was used to collect
information on patients\u2019 demographic variables and probable risk
factors for HBV transmission. Results: Overall, 3.5% of HIV patients
were seropositive to HBsAg and the difference between seroprevalence
rates and patients\u2019 age as well as gender was not statistically
significant (p>0.05). There was significant difference between
patients\u2019 demographic variables such as marital status (p=0.013)
and educational level (p=0.004) and HBsAg seropositivity. Patients with
a history of surgical applications (p=0.01) and who indulged in
alcoholism (p=0.03) significantly had higher rates of concomitant
HIV/HBV infection in the study area. Conclusion: Our findings
underscore the importance of routine screening for HBV in the HIV
infected populations especially in developing countries where the
infection is endemic. We advocate for public enlightenment programmes
on routes of virus acquisitions with a view to reduce the morbidity and
mortality associated HIV/HBV co-infection. DOI:
https://dx.doi.org/10.4314/ahs.v19i2.17 Cite as: Omatola CA, Idofe J,
Okolo M-LO, Adejo PO, Maina MM, Oyiguh JA. Sero-prevalence of HBV among
people living with HIV inAnyigba, Kogi State, Nigeria. Afri Health
Sci.2019;19(2): 1938-1946. https://dx.doi.org/10.4314/ahs.v19i2.1