Seroprevalence of HBV among people living with HIV in Anyigba, Kogi State, Nigeria

Abstract

Background: Co-infection of HBV with HIV is associated with significant morbidity and mortality globally. In spite of increasing reports of HIV/HBV co-morbidities in Nigeria, little or no data exists on this subject in Anyigba. Therefore,we determined the prevalence of hepatitis B surface antigenemia among HIV positive patients on anti-retroviral treatment programme in Anyigba, Kogi State, North-Central Nigeria. Methods: Sera samples obtained from 200 consented HIV patients were screened for HBsAg using the commercial rapid test membrane-based qualitative immunoassay. A structured questionnaire was used to collect information on patients\u2019 demographic variables and probable risk factors for HBV transmission. Results: Overall, 3.5% of HIV patients were seropositive to HBsAg and the difference between seroprevalence rates and patients\u2019 age as well as gender was not statistically significant (p>0.05). There was significant difference between patients\u2019 demographic variables such as marital status (p=0.013) and educational level (p=0.004) and HBsAg seropositivity. Patients with a history of surgical applications (p=0.01) and who indulged in alcoholism (p=0.03) significantly had higher rates of concomitant HIV/HBV infection in the study area. Conclusion: Our findings underscore the importance of routine screening for HBV in the HIV infected populations especially in developing countries where the infection is endemic. We advocate for public enlightenment programmes on routes of virus acquisitions with a view to reduce the morbidity and mortality associated HIV/HBV co-infection. DOI: https://dx.doi.org/10.4314/ahs.v19i2.17 Cite as: Omatola CA, Idofe J, Okolo M-LO, Adejo PO, Maina MM, Oyiguh JA. Sero-prevalence of HBV among people living with HIV inAnyigba, Kogi State, Nigeria. Afri Health Sci.2019;19(2): 1938-1946. https://dx.doi.org/10.4314/ahs.v19i2.1