Dressing a black hole with non-minimally coupled scalar field hair

We investigate the possibility of dressing a four-dimensional black hole with classical scalar field hair which is non-minimally coupled to the space-time curvature. Our model includes a cosmological constant but no self-interaction potential for the scalar field. We are able to rule out black hole hair except when the cosmological constant is negative and the constant governing the coupling to the Ricci scalar curvature is positive. In this case, non-trivial hairy black hole solutions exist, at least some of which are linearly stable. However, when the coupling constant becomes too large, the black hole hair becomes unstable.Comment: 17 pages, 7 figures, uses iopart.cls. Minor changes, accepted for publication in Classical and Quantum Gravit

Lysosomal acid lipase deficiency – an underestimated cause of hypercholesterolemia in children

Lysosomal acid lipase deficiency (LAL-D) is a rare, progressive, autosomal recessive disease, which develops due to impaired degradation and subsequent intra-lysosomal accumulation of triglycerides and cholesterol esters causing dyslipidemia. The clinical manifestations of the disease presumably depend on the residual activity of the enzyme, lysosomal acid lipase. A profound deficiency of the enzyme known as Wolman’s disease has an onset in the first 6 months of life. The disease reveals itself by dyspeptic disorders in the form of vomiting and diarrhea, lack of weight gain, hepatosplenomegaly, and adrenal calcification. If the Wolman’s disease is not treated, children die within the first 6 months as a result of exhaustion caused by malabsorption syndrome combined with progressive deterioration of liver and adrenal glands. Partial deficiency of lysosomal acid lipase manifests itself at a later age and is called cholesterol ester storage disease. Its clinical presentations include hepatosplenomegaly, elevated transaminases, hypercholesterolemia, and, in some cases, hypertriglyceridemia. Liver failure is the main cause of death in the natural course of cholesterol ester storage disease. Delayed diagnosis of the disease leads to its progression causing irreversible liver damage. The implementation of mass screening programs with the determination of cholesterol levels in childhood is critical to identifying asymptomatic patients.The article presents a clinical case of a patient aged 3 years. The molecular genetic testing showed a mutation in exon 8 of the LIPA gene: NM_000235.3:c.894G>A synonymous variant in the homozygous state. It was also found that both parents of the girl had this type of mutation in the heterozygous state. The patient was prescribed sebelipase alfa in a dose of 1 mg/kg once every 14 days. The treatment was well tolerated. Due to the early verification of the diagnosis and timely pathogenetic therapy, the prognosis of the course of LAL-D, the duration and quality of life of the child were considered to be favourable.Raising the awareness of doctors along with the introduction of effective screening programs for the timely detection of dyslipidemia in children contributes to timely diagnosis and early initiation of pathogenetic therapy, which can increase the life expectancy of patients with lysosomal acid lipase deficiency and improve their quality of life

Metabolic syndrome and lower urinary tract symptoms

We study the relationship between metabolic syndrome (MS) and urinary disorders. This article shows that MS is a risk factor for cardiovascular disasters, insulin resistance, and androgen deficiency in developed and developing countries. Methods: Patients with MS had statistically significantly more symptomatic on the International Prostatic Symptom Score scale and a lower quality of life inde

The lower urinary tract symptoms in patients after transurethral resection of benign prostatic hyperplasia

We performed a retrospective analysis of medical records and prospective evaluation of TUR in the long term, which was carried out in patients with BPH. The real picture of the possibilities of examination and treatment of patients with LUTS together with urological can be accessed from portal UroWeb.ru. A survey of urologists in the public domain was conducted. Such an indication, as the ineffectiveness of conservative therapy has been established for young patients with a small volume of the prostat

The management of technology transfer and its impact on business activity and financial security in developing countries.

видання входить до наукометричної бази Web of Science Core Collection: Emerging Sources Citation IndexЦя стаття присвячена оцінці впливу трансферу технологій на країни, що розвиваються. Основною метою дослідження є визначення впливу виробництва та трансферу технологій на рівень зростання країн, що розвиваються. Для досягнення мети було проаналізовано статистичні дані про витрати на дослідження та розробки (НДДКР), ВВП, трансфер технологій та інноваційний розвиток за 2014-2020 роки. Згідно з результатами дослідження, країни, які інвестують в інновації, мають великий технологічний потенціал, що дозволяє розвивати економіку швидше, ніж шляхом накопичення капіталу. Найвпливовішим показником сучасного розвитку технологій є рівень витрат на дослідження та розробки (R&D).This article is devoted to assessing the impact of technology transfer on developing countries. The main purpose of the study is to determine the impact of production and technology transfer on the level of growth of developing countries. In order to achieve the goal, statistical data on research and development (R&D) expenditures, GDP, technology transfer and innovation development for 2014-2020 were analyzed. According to the results of the study, the countries investing in innovations have a great technological potential, which allows to develop the economy more rapidly, than by capital accumulation. The most influential indicator of technology modern development is the level of spending in R&D

Geoecological validation of mechanisms and parameters of physical-chemical processes facilitating the in-depth processing of complex suphide ores and mining wastes

Abstract. The advisability of processing copper-nickel ore dressing tailings of current production has been substantiated. The optimal parameters of metal leaching with sulphuric acid have been determined. In laboratory experiments the geotechnological extraction of non-ferrous metals from a leaching layer representing a tailing material of fraction +0.063 mm has been studied. When investigating the geotechnological processes of nonferrous metal extraction on the basis of two copper-zinc ore deposits located in the Urals, the authors have come to the conclusion that heap leaching is of little use for the ores of the Letneye deposit. Leaching results for the Yaman-Kasy ore have shown more promise. Аннотация. Показана целесообразность переработки хвостов обогащения медно-никелевых руд текущего производства. Определены оптимальные параметры сернокислотного выщелачивания металлов. В лабораторных условиях исследовано геотехнологическое извлечение цветных металлов из выщелачиваемого слоя, подготовленного из хвостов фракции +0.063 мм. Изучение геотехнологических процессов извлечения цветных металлов из медно-цинковых руд двух месторождений Урала показало, что руды месторождения Летнего малоприемлемы для кучного выщелачивания. Существенно лучшие результаты получены при выщелачивании руды месторождения Яман-Касы

Field-free orientation of CO molecules by femtosecond two-color laser fields

We report the first experimental observation of non-adiabatic field-free orientation of a heteronuclear diatomic molecule (CO) induced by an intense two-color (800 and 400 nm) femtosecond laser field. We monitor orientation by measuring fragment ion angular distributions after Coulomb explosion with an 800 nm pulse. The orientation of the molecules is controlled by the relative phase of the two-color field. The results are compared to quantum mechanical rigid rotor calculations. The demonstrated method can be applied to study molecular frame dynamics under field-free conditions in conjunction with a variety of spectroscopy methods, such as high-harmonic generation, electron diffraction and molecular frame photoemission

Sigma-model for Generalized Composite p-branes

A multidimensional gravitational model containing several dilatonic scalar fields and antisymmetric forms is considered. The manifold is chosen in the form M = M_0 x M_1 x ... x M_n, where M_i are Einstein spaces (i > 0). The block-diagonal metric is chosen and all fields and scale factors of the metric are functions on M_0. For the forms composite (electro-magnetic) p-brane ansatz is adopted. The model is reduced to gravitating self-interacting sigma-model with certain constraints. In pure electric and magnetic cases the number of these constraints is m(m - 1)/2 where m is number of 1-dimensional manifolds among M_i. In the "electro-magnetic" case for dim M_0 = 1, 3 additional m constraints appear. A family of "Majumdar-Papapetrou type" solutions governed by a set of harmonic functions is obtained, when all factor-spaces M_k are Ricci-flat. These solutions are generalized to the case of non-Ricci-flat M_0 when also some additional "internal" Einstein spaces of non-zero curvature are added to M. As an example exact solutions for D = 11 supergravity and related 12-dimensional theory are presented.Comment: 33 pages, Latex. Some corrections and rearrangements are mad

"No-Scalar-Hair" Theorems for Nonminimally Coupled Fields with Quartic Self-Interaction

Self-gravitating scalar fields with nonminimal coupling to gravity and having a quartic self-interaction are considered in the domain of outer communications of a static black hole. It is shown that there is no value of the nonminimal coupling parameter $\zeta$ for which nontrivial static black hole solutions exist. This result establishes the correctness of Bekenstein ``no-scalar-hair'' conjecture for quartic self-interactions.Comment: 8 pages, RevTeX