Propiedades antioxidantes de dos nuevos derivados lipofílicos del ácido gálico

The effectiveness of two lipophilic derivatives of the natural phenol, gallic acid (GA), synthesized using methyl gallate as starting material was investigated. The antioxidant activities of these novel phenolics compared to GA, tert-butylhydroquinone (TBHQ) and butylated hydroxytoluene (BHT) were evaluated in bulk oil, emulsion and the DPPH systems. The results showed that the new compounds effectively delayed lipid oxidation much better than GA and other antioxidants under Rancimat (100-140 °C) and emulsion tests. In the bulk oil system at 65 °C, they still behaved better than GA, but TBHQ had the highest activity. Thus, replacing the electron-withdrawing carboxylic group on GA by covalently linking sterically hindered phenols to its phenyl ring increased its lipophilicity and also resulted in synergistic effects which improved overall antioxidant activity through stabilization of the phenoxy radical. These new antioxidant variants satisfy industrial demands for bioactive ingredients with strong antioxidant potentials under different food processing conditions.Se aporta información sobre de la eficacia de dos derivados lipofílicos de fenoles naturales derivados del ácido gálico (GA) y sintetizados utilizando galato de metilo como material de partida. Las actividades antioxidantes de estos nuevos compuestos fenólicos en comparación con el GA, terc-butilhidroquinona (TBHQ) y butil hidroxitolueno (BHT) se evaluaron en aceites, sistemas emulsionados y mediante DPPH. Los resultados mostraron que los nuevos compuestos retrasaron efectivamente la oxidación de lípidos mucho más fuerte que el GA y otros antioxidantes mediante Rancimat (100-140 °C) y pruebas de emulsión. En el aceite a 65 °C, se comportaron mejor que el GA, pero el TBHQ tuvo la actividad más alta. Por lo tanto, reemplazar el grupo carboxílico en GA al unir covalentemente fenoles impedidos estéricamente a su anillo de fenilo ayudó a aumentar su lipofilia y también dio como resultado efectos sinérgicos que mejoraron la actividad antioxidante general a través de la estabilización del radical fenoxi. Estas nuevas variantes de antioxidantes satisfacen la demanda industrial de ingredientes bioactivos con un fuerte potencial antioxidante en diferentes condiciones de procesamiento de alimentos

Naringin supplementation affects performance, carcass traits, meat quality and oxidative stability of finishing pigs

Naringin is a major flavanone derivate that has many important biological functions in animals. However, its effect on pigs is unknown. The aim of this study was to investigate the effect of naringin supplementation on performance, carcass traits, meat quality and oxidative stability in finishing pigs. Ninety-six pigs, with an average initial body weight of 66.2 ± 0.63 kg, were randomly divided into four groups. One group was fed a basal diet without supplementation (control), and the three others were fed diets supplemented with 0.5, 1.0 or 1.5 g naringin /kg DM of feed for 50 days. Each treatment was replicated six times with four pigs per replicate. Feed and water were available ad libitum. The 0.5 g/kg naringin treatment group had an improved loin eye muscle area, reduced serum triglycerides and were leaner compared with the other groups. Pigs in the 1.5 g/kg naringin treatment had higher pH45min values and inosine monophosphate concentrations, and lower MyHC IIb mRNA expression in muscle than the other groups. MyHC IIa mRNA expression was significantly up-regulated in all naringin-supplemented diet groups. Naringin significantly increased superoxide dismutase (SOD) activity and total anti-oxidative capacity in meat, as well as SOD and glutathione peroxidase activity in the liver. These results indicate that the dietary addition of naringin at 0.5 g/kg improved carcass characteristics, while 1.5 g/kg improved the oxidative stability and pork quality in finishing pigs. Keywords: antioxidant capacity; carcass characteristics; naringin-supplemented diets; pork qualit

Evaluación comparativa de la composición química y las actividades antimicrobianas de los aceites esenciales extraídos de diferentes quimiotipos de Cinnamomum camphora (L.) Presl

The purpose of this study is to determine the chemical composition of the essential oils of Cinnamomum camphora (L.) Presl leaves (CCPL) from 5 different habitats in China by GC-MS, and to evaluate their antimicrobial activities against 3 foodborne pathogens, using a paper disc diffusion method. A total of 30 compounds were identified with a predominance of oxygenated monoterpenes, including linalool (42.65%-96.47%), eucalyptol (39.07%-55.35%) and camphor (26.08%) as well as monoterpene hydrocarbons such as sabinene (6.18%-12.93%) and α-terpineol (8.19%-13.81%). Through cluster analysis, CCPL from 5 different habitats can be well divided into 2 categories. Combining with principal component analysis, the habitats can be better correlated with the chemical constituents of the essential oils. The antimicrobial activities of 5 extracted essential oils against 2 gram-negative bacteria and one gram-positive bacteria were assessed. It showed that the essential oil extracted from the CCPL harvested in Jinxi had the strongest antibacterial property. The results of this study provided basis for resource identification of CCPL and quality difference identification of essential oils. Research on the antibacterial properties of several pathogenic strains has proved its application value as a natural food preservative.El objetivo de este estudio es determinar la composición química de los aceites esenciales de hojas de Cinnamomum camphora (L.) Presl (CCPL) de 5 hábitats diferentes de China mediante GC-MS, y evaluar sus actividades antimicrobianas contra 3 patógenos transmitidos por los alimentos, utilizando un método de difusión de disco de papel. Se identificaron un total de 30 compuestos, con predominio de monoterpenos oxigenados, entre ellos linalol (42,65%-96,47%), eucaliptol (39,07%-55,35%) y alcanfor (26,08%) así como hidrocarburos monoterpenos como el sabineno (6,18%-12,93%) y α-terpineol (8,19%-13,81%). A través del análisis de conglomerados, los CCPL de 5 hábitats diferentes se pueden dividir bien en 2 categorías. En combinación con el análisis de componentes principales, los hábitats se pueden correlacionar mejor con los componentes químicos de los aceites esenciales. Se evaluaron las actividades antimicrobianas de 5 aceites esenciales extraídos contra 2 bacterias gramnegativas y una bacteria grampositiva. Se demuestra que el aceite esencial extraído del CCPL cosechado en Jinxi tenía la propiedad antibacteriana más fuerte. Los resultados de este estudio proporcionaron la base para la identificación de recursos de CCPL y la identificación de diferencias de calidad de los aceites esenciales. La investigación sobre las propiedades antibacterianas de varias cepas patógenas ha demostrado su valor de aplicación como conservante natural de alimentos

Using system simulation to search for the optimal multi-ordering policy for perishable goods

[EN] This paper explores the possibility that perishable goods can be ordered several times in a single period after considering the cost of Marginal contribution, Marginal loss, Shortage, and Purchasing under stochastic demand. In order to determine the optimal ordering quantity to improve the traditional newsvendor and maximize the total expected profits, and then sensitivity analysis is taken to realize the influence of the parameters on total expected profits and decision variables respectively. In addition, this paper designed a multi-order computerized system with Monte Carlo method to solve the optimal solution under stochastic demand. Based on numerical examples, this paper verified the feasibility and efficiency of the proposed model. Finally, several specific conclusions are drawn for practical applications and future studies.Huang, Y.; Chang, X.; Ding, Y. (2019). Using system simulation to search for the optimal multi-ordering policy for perishable goods. International Journal of Production Management and Engineering. 7(1):49-62. https://doi.org/10.4995/ijpme.2019.10745SWORD496271Azoury, K.S., Miller, B.L. (1984). A comparison of the optimal ordering levels of bayesian and non-bayesian inventory models, Management Science, 30(8), 993-1003. https://doi.org/10.1287/mnsc.30.8.993Alfares, H.K., Elmorra, H.H. (2005). The distribution-free newsboy problem: extensions to the shortage penalty case, International Journal of Production Economics, 93-94(8), 465-477. https://doi.org/10.1016/j.ijpe.2004.06.043Chung, C.S., Flynn, J. (2001). A newsboy problem with reactive production, Computers & Operations Research, 28(8), 751-765. https://doi.org/10.1016/S0305-0548(00)00006-XChun, Y.H. (2003). Optimal pricing and ordering policies for perishable commodities, European Journal of Operational Research, 144(1), 68-82. https://doi.org/10.1016/S0377-2217(01)00351-4Chen, L.H., Chen, Y.C. (2009). A newsboy problem with a simple reservation arrangement. Computers & Industrial Engineering, 56(1), 157-160. https://doi.org/10.1016/j.cie.2008.04.010Dian, J.R. (1990). A high-low search algorithm for a newsboy problem with delayed information feedback. Operations Research, 38(5), 838-846. https://doi.org/10.1287/opre.38.5.838Dye, C.Y., Ouyang, L.Y. (2005). An EOQ model for perishable items under stock-dependent selling rate and time-dependent partial backlogging. European Journal of Operational Research, 163(3), 776-783. https://doi.org/10.1016/j.ejor.2003.09.027Fujiwara, O., Soewandi, H., Sedarage, D. (1997). An optimal ordering and issuing policy for a two-stage inventory system for perishable products. European Journal of Operational Research, 99(2), 412-424. https://doi.org/10.1016/S0377-2217(95)00365-7Gallego, G., Moon, I. (1993). The distribution free newsboy problem: review and extensions. Journal of the Operational Research Society, 44(8), 825-834. https://doi.org/10.1057/jors.1993.141Khouja, M. (1999). The single-period (news-vendor) problem: literature review and suggestions for future research. Omega, 27(5), 537-553. https://doi.org/10.1016/S0305-0483(99)00017-1Khouja, M.J. (2000). Optimal ordering, discounting, and pricing in the single-period problem. International Journal of Production Economics, 65(2), 201-216. https://doi.org/10.1016/S0925-5273(99)00027-4Lau, H., Lau, H. (1998). Decision models for single-period products with two ordering opportunities. International Journal of Production Economics, 55(1), 57-70. https://doi.org/10.1016/S0925-5273(98)00040-1Padmanabhan, G., Vrat, P. (1995). EOQ models for perishable items under stock dependent selling rate. European Journal of Operational Research, 86(2), 281-292. https://doi.org/10.1016/0377-2217(94)00103-JPando, V., Luis, A.S.J., Juan, G.L., Sicilia, J. (2013). A newsboy problem with an emergency order under a general backorder rate function. Omega, 41(6), 1020-1028. https://doi.org/10.1016/j.omega.2013.01.003Zheng, M., Wu, K., Shu, Y. (2016). Newsvendor problems with demand forecast updating and supply constraints. Computers & Operations Research, 67, 193-206. https://doi.org/10.1016/j.cor.2015.10.00

Preparación de sustitutos de grasa de leche humana y mejora de su estabilidad oxidativa

1,3-Dioleoyl-2-palmitoylglycerol (OPO) was synthesized by enzymatic interesterification using palm stearin rich in tripalmitin (PPP) and ethyl oleate. Enzymatic interesterification parameters such as temperature, water content, enzyme load, and substrate molar ratio were optimized. High contents of C52 (primarily OPO and its isomeric compounds) production (46.7%) and sn-2 palmitic acid (PA) content of 75.3% were detected. In addition, OPO-human milk fat substitute (HMFS) was blended with coconut, soybean, algal and microbial oils at a weight ratio of 0.70:0.18:0.11:0.004:0.007 to simulate fatty acids in human milk fat (HMF) according to the mathematical model. The main and important fatty acids in the Final-HMFS were within the ranges of those present in HMF. The Final-HMFS could promote the absorption of fats and minerals and the development of retina tissues in infants. The mixture of L-ascorbyl palmitate (L-AP) and vitamin E (VE) resulted in a synergistic antioxidant effect both in OPO-HMFS and OPO-HMFS emulsions. This finding has great significance in improving the quality and extending shelf-life of HMFS.Se sintetizó el 1,3-dioleoil-2-palmitoilglicerol (OPO), utilizando estearina de palma rica en tripalmitina (PPP) y oleato de etilo, mediante interesterificación enzimática. Se optimizaron los parámetros de la interesterificación enzimática, como la temperatura, el contenido de agua, la carga de enzimas y la relación molar del sustrato. Se lograron altos rendimientos de C52 (principalmente OPO y sus isómeros, 46,7%) y un contenido de ácido palmítico (PA) en sn-2 del 75,3%. Además, el sustituto graso de leche humana OPO (HMFS), se mezcló con aceites de coco, soja, algas y microbianos, en una proporción en peso de 0,70:0,18:0,11:0,004:0,007 para simular los ácidos grasos de la leche humana (HMF) de acuerdo con un modelo matemático. Los ácidos grasos principales e importantes en HMFS-Final estaban casi dentro de los rangos de los presentes en HMF. El HMFS-Final podría promover la absorción de grasas y minerales y el desarrollo de los tejidos de la retina en los bebés. La mezcla de palmitato de L-ascorbilo (L-AP) y vitamina E (VE) resultó tener un efecto antioxidante sinérgico, tanto en la emulsión OPO-HMFS como en la OPO-HMFS. Este hallazgo tiene una gran importancia para mejorar la calidad y prolongar la vida útil de HMFS

Low Mach number effect in simulation of high Mach number flow

In this note, we relate the two well-known difficulties of Godunov schemes: the carbuncle phenomena in simulating high Mach number flow, and the inaccurate pressure profile in simulating low Mach number flow. We introduced two simple low-Mach-number modifications for the classical Roe flux to decrease the difference between the acoustic and advection contributions of the numerical dissipation. While the first modification increases the local numerical dissipation, the second decreases it. The numerical tests on the double-Mach reflection problem show that both modifications eliminate the kinked Mach stem suffered by the original flux. These results suggest that, other than insufficient numerical dissipation near the shock front, the carbuncle phenomena is strongly relevant to the non-comparable acoustic and advection contributions of the numerical dissipation produced by Godunov schemes due to the low Mach number effect.Comment: 9 pages, 1 figur

Effect of stress-triaxiality on void growth in dynamic fracture of metals: a molecular dynamics study

The effect of stress-triaxiality on growth of a void in a three dimensional single-crystal face-centered-cubic (FCC) lattice has been studied. Molecular dynamics (MD) simulations using an embedded-atom (EAM) potential for copper have been performed at room temperature and using strain controlling with high strain rates ranging from 10^7/sec to 10^10/sec. Strain-rates of these magnitudes can be studied experimentally, e.g. using shock waves induced by laser ablation. Void growth has been simulated in three different conditions, namely uniaxial, biaxial, and triaxial expansion. The response of the system in the three cases have been compared in terms of the void growth rate, the detailed void shape evolution, and the stress-strain behavior including the development of plastic strain. Also macroscopic observables as plastic work and porosity have been computed from the atomistic level. The stress thresholds for void growth are found to be comparable with spall strength values determined by dynamic fracture experiments. The conventional macroscopic assumption that the mean plastic strain results from the growth of the void is validated. The evolution of the system in the uniaxial case is found to exhibit four different regimes: elastic expansion; plastic yielding, when the mean stress is nearly constant, but the stress-triaxiality increases rapidly together with exponential growth of the void; saturation of the stress-triaxiality; and finally the failure.Comment: 35 figures, which are small (and blurry) due to the space limitations; submitted (with original figures) to Physical Review B. Final versio