1,207 research outputs found

    Extending Ethos in Digital Rhetorics

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    This dissertation researched the concept of ethos, or appeal to authority or trust, on the social media platform, Twitter. Looking at collections of tweets, I found that the characteristics of the Twitter platform, as well as the general qualities of writing online, pushed users to use short cuts to trust, such as focusing in on specific buzz words, or through referencing well known organizations and individuals. Users also used internet culture as its own source of authority. They demonstrated that they were up to date on the latest trends and memes, and so were trustworthy accounts to follow. Users appealed to ethos this way because Twitter conversations occurred faster and farther, and with people who most users were either unfamiliar with or who were completely anonymous. Essentially, Twitter user rely on the short cuts to trust and authority in conversations because they are less often engaging with a stable, known audience. Twitter users must continually reassert and define themselves again as their posts circulate widely across and beyond the platform

    A user's guide to PDE models for chemotaxis

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    Mathematical modelling of chemotaxis (the movement of biological cells or organisms in response to chemical gradients) has developed into a large and diverse discipline, whose aspects include its mechanistic basis, the modelling of specific systems and the mathematical behaviour of the underlying equations. The Keller-Segel model of chemotaxis (Keller and Segel in J Theor Biol 26:399-415, 1970; 30:225- 234, 1971) has provided a cornerstone for much of this work, its success being a consequence of its intuitive simplicity, analytical tractability and capacity to replicate key behaviour of chemotactic populations. One such property, the ability to display "auto-aggregation", has led to its prominence as a mechanism for self-organisation of biological systems. This phenomenon has been shown to lead to finite-time blow-up under certain formulations of the model, and a large body of work has been devoted to determining when blow-up occurs or whether globally existing solutions exist. In this paper, we explore in detail a number of variations of the original Keller-Segel model. We review their formulation from a biological perspective, contrast their patterning properties, summarise key results on their analytical properties and classify their solution form. We conclude with a brief discussion and expand on some of the outstanding issues revealed as a result of this work. © Springer-Verlag 2008

    Mathematical modelling of glioma growth: The use of Diffusion Tensor Imaging (DTI) data to predict the anisotropic pathways of cancer invasion

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    The nonuniform growth of certain forms of cancer can present significant complications for their treatment, a particularly acute problem in gliomas. A number of experimental results have suggested that invasion is facilitated by the directed movement of cells along the aligned neural fibre tracts that form a large component of the white matter. Diffusion tensor imaging (DTI) provides a window for visualising this anisotropy and gaining insight on the potential invasive pathways. In this paper we develop a mesoscopic model for glioma invasion based on the individual migration pathways of invading cells along the fibre tracts. Via scaling we obtain a macroscopic model that allows us to explore the overall growth of a tumour. To connect DTI data to parameters in the macroscopic model we assume that directional guidance along fibre tracts is described by a bimodal von Mises-Fisher distribution (a normal distribution on a unit sphere) and parametrised according to the directionality and degree of anisotropy in the diffusion tensors. We demonstrate the results in a simple model for glioma growth, exploiting both synthetic and genuine DTI datasets to reveal the potentially crucial role of anisotropic structure on invasion. © 2013 Elsevier Ltd

    Navigating the flow:individual and continuum models for homing in flowing environments

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    Navigation for aquatic and airborne species often takes place in the face of complicated flows, from persistent currents to highly unpredictable storms. Hydrodynamic models are capable of simulating flow dynamics and provide the impetus for much individual-based modelling, in which particle-sized individuals are immersed into a flowing medium. These models yield insights on the impact of currents on population distributions from fish eggs to large organisms, yet their computational demands and intractability reduce their capacity to generate the broader, less parameter-specific, insights allowed by traditional continuous approaches. In this paper, we formulate an individual-based model for navigation within a flowing field and apply scaling to derive its corresponding macroscopic and continuous model. We apply it to various movement classes, from drifters that simply go with the flow to navigators that respond to environmental orienteering cues. The utility of the model is demonstrated via its application to ‘homing’ problems and, in particular, the navigation of the marine green turtle Chelonia mydas to Ascension Island

    Transport and anisotropic diffusion models for movement in oriented habitats

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    A common feature of many living organisms is the ability to move and navigate in heterogeneous environments. While models for spatial spread of populations are often based on the diffusion equation, here we aim to advertise the use of transport models; in particular in cases where data from individual tracking are available. Rather than developing a full general theory of transport models, we focus on the specific case of animal movement in oriented habitats. The orientations can be given by magnetic cues, elevation profiles, food sources, or disturbances such as seismic lines or roads. In this case we are able to present and contrast the three most common scaling limits, (i) the parabolic scaling, (ii) the hyperbolic scaling, and (iii) the moment closure method. We clearly state the underlying assumptions and guide the reader to an understanding of which scaling method is used in what kind of situations. One interesting result is that the macroscopic drift velocity is given by the mean direction of the underlying linear features, and the diffusion is given by the variance-covariance matrix of the underlying oriented habitat. We illustrate our findings with specific applications to wolf movement in habitats with seismic lines. © 2013 Springer-Verlag Berlin Heidelberg

    Open reduction and corrective ulnar osteotomy for missed radial head dislocations in children

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    The treatment of chronic radial head dislocation remains controversial. Open reduction of the radial head in combination with correction of malalignment with ulnar osteotomy can be the key to a good surgical result. Between 2001 and 2006, 9 (6 female, 3 male, average age 8.4 (5-11) years) patients were treated surgically for chronic radial head dislocation by one surgeon. The time between trauma and surgery was 7 (1.5-14) months. The procedure consisted of open reduction of the dislocated radial head and reconstruction of the annular ligament in combination with an ulnar osteotomy. An upper arm cast was applied with the forearm in neutral rotation for six weeks. Plates were removed in all patients. Clinical and radiological evaluation took place preoperatively and after an average of 23 (10-49) months. At radiograph 8/9 showed a reduced radial head; in one an anterior subluxation was seen. The range of motion remained the same in 4 patients who had a full range of motion preoperatively. In 2/5 patients with loss of range of motion preoperatively, improvement was seen. There were no serious surgical complications beside one infection. Open reduction and corrective ulnar osteotomy shows good results for missed radial head dislocations in children

    Imaging the dust sublimation front of a circumbinary disk

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    We present the first near-IR milli-arcsecond-scale image of a post-AGB binary that is surrounded by hot circumbinary dust. A very rich interferometric data set in six spectral channels was acquired of IRAS08544-4431 with the new RAPID camera on the PIONIER beam combiner at the Very Large Telescope Interferometer (VLTI). A broadband image in the \textit{H} band was reconstructed by combining the data of all spectral channels using the SPARCO method. We spatially separate all the building blocks of the IRAS08544-4431 system in our milliarcsecond-resolution image. Our dissection reveals a dust sublimation front that is strikingly similar to that expected in early-stage protoplanetary disks, as well as an unexpected flux signal of ∼\sim4\% from the secondary star. The energy output from this companion indicates the presence of a compact circum-companion accretion disk, which is likely the origin of the fast outflow detected in Hα\alpha. Our image provides the most detailed view into the heart of a dusty circumstellar disk to date. Our results demonstrate that binary evolution processes and circumstellar disk evolution can be studied in detail in space and over time.Comment: PR @ http://www.eso.org/public/news/eso1608

    Absolute dimensions of solar-type eclipsing binaries. EF Aquarii: a G0 test for stellar evolution models

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    Recent studies have shown that stellar chromospheric activity, and its effect on convective energy transport in the envelope, is most likely the cause of significant radius and temperature discrepancies between theoretical evolution models and observations. We aim to determine absolute dimensions and abundances for the solar-type detached eclipsing binary EF Aqr, and to perform a detailed comparison with results from recent stellar evolutionary models. uvby-beta standard photometry was obtained with the Stromgren Automatic Telescope. The broadening function formalism was applied on spectra observed with HERMES at the Mercator telescope in La Palma, to obtain radial velocity curves. Masses and radii with a precision of 0.6% and 1.0% respectively have been established for both components of EF Aqr. The active 0.956 M_sol secondary shows star spots and strong Ca II H and K emission lines. The 1.224 M_sol primary shows signs of activity as well, but at a lower level. An [Fe/H] abundance of 0.00+-0.10 is derived with similar abundances for Si, Ca, Sc, Ti, V, Cr, Co, and Ni. Solar calibrated evolutionary models such as Yonsei-Yale, Victoria-Regina and BaSTI isochrones and evolutionary tracks are unable to reproduce EF Aqr, especially for the secondary, which is 9% larger and 400 K cooler than predicted. Models adopting significantly lower mixing length parameters l/H_p remove these discrepancies, as seen in other solar type binaries. For the observed metallicity, Granada models with a mixing length of l/H_p=1.30 (primary) and 1.05 (secondary) reproduce both components at a common age of 1.5+-0.6 Gyr. Observations of EF Aqr suggests that magnetic activity, and its effect on envelope convection, is likely to be the cause of discrepancies in both radius and temperature, which can be removed by adjusting the mixing length parameter of the models downwards.Comment: 11 pages, 8 figures, accepted for publication by A&
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