Electro-Mechanical Fredericks Effects in Nematic Gels

The solid nematic equivalent of the Fredericks transition is found to depend on a critical field rather than a critical voltage as in the classical case. This arises because director anchoring is principally to the solid rubbery matrix of the nematic gel rather than to the sample surfaces. Moreover, above the threshold field, we find a competition between quartic (soft) and conventional harmonic elasticity which dictates the director response. By including a small degree of initial director misorientation, the calculated field variation of optical anisotropy agrees well with the conoscopy measurements of Chang et al (Phys.Rev.E56, 595, 1997) of the electro-optical response of nematic gels.Comment: Latex (revtex style), 5 EPS figures, submitted to PRE, corrections to discussion of fig.3, cosmetic change

Transcriptome pathways unique to dehydration tolerant relatives of modern wheat

Among abiotic stressors, drought is a major factor responsible for dramatic yield loss in agriculture. In order to reveal differences in global expression profiles of drought tolerant and sensitive wild emmer wheat genotypes, a previously deployed shock-like dehydration process was utilized to compare transcriptomes at two time points in root and leaf tissues using the Affymetrix GeneChip(R) Wheat Genome Array hybridization. The comparison of transcriptomes reveal several unique genes or expression patterns such as differential usage of IP(3)-dependent signal transduction pathways, ethylene- and abscisic acid (ABA)-dependent signaling, and preferential or faster induction of ABA-dependent transcription factors by the tolerant genotype that distinguish contrasting genotypes indicative of distinctive stress response pathways. The data also show that wild emmer wheat is capable of engaging known drought stress responsive mechanisms. The global comparison of transcriptomes in the absence of and after dehydration underlined the gene networks especially in root tissues that may have been lost in the selection processes generating modern bread wheats

Advances in single carrier block modulation with frequency domain processing

International audienceThis special issue focuses on single carrier block modulation (SC-BM) with frequency domain processing. This class of modulation and multiple access schemes complements the orthogonal frequency division multiple access (OFDMA) and its variations. For example, LTE (the long term evolution of the 3GPP standard), and LTE-Advanced, employ OFDMA in the downlink (base stations to mobiles) and SC-FDMA, a version of SC-BM in the uplink (mobiles to base stations). The main reason for adapting the technology of SC-FDMA for uplink LTE is the fact that OFDMA has high "peak-to-average power ratio" (PAPR), which is a disadvantage for mobile devices that are limited by power availability. Besides its advantage of low PAPR, SC-BM technology has a similar performance/complexity to that of OFDMA, and simple frequency domain equalization methods for combating dispersive channels. There were 17 papers submitted to this special issue. All had merits, but the review process reduced the number of accepted papers to 9. The accepted papers cover a number of novel and advanced aspects of single carrier block modulation with frequency domain processing: near-optimal nonlinear and iterative equalization techniques; applications to CDMA, MIMO and ARQ; channel estimation; and application to free-space optical transmission. Following is a summary of the papers. In the paper "Iterative Successive Interference Cancellation for Quasi-Synchronous Block Spread CDMA Based on the Orders of the Times of Arrival", Wang, Bocus, and Coon [1] describe an interference cancellation scheme based on the times of arrival of the signals from different users, and they show that for practical channels this ordering criterion is equivalent to ordering with respect to decreasing average SINR. In "Complexity Reduced MLD Based on QR Decomposition in OFDM MIMO Multiplexing with Frequency Domain Spreading and Code Multiplexing", Nagatomi, Kawai, and Higuchi [2] propose a reduced-complexity maximum likelihood signal detection method for MIMO-OFDM systems with frequency-domain spreading and code multiplexing. They show how to exploit signal orthogonalization based on QR decomposition of the product of the channel and spreading code matrices in the frequency domain to obtain significant complexity reductions. In "Frequency-domain Block Signal detection with QRM-MLD for Training Sequence-aided Single-carrier Transmission", Yamamoto, Takeda and Adachi [3] propose replacement of the cyclic prefix with a known training sequence. The object is to improve BER performance of an equalization scheme which uses QR decomposition with M-algorithm detection, while keeping the number of surviving paths low for reduced complexity. The scheme is especially effective for 16QAM and 64QAM modulation. The paper "Joint Iterative Tx/Rx MMSE-FDE and ISI Cancellation for Single-carrier Hybrid ARQ with Chase Combining" by Takeda and Adachi [4] applies transmitter and receiver equalization and iterative intersymbol interference cancellation to a system with hybrid ARQ transmission, Chase combining and antenna diversity. The equalizer parameters at both transmitter and receiver are optimized for each retransmission. The paper "Novel Techniques of Single Carrier Frequency Domain Equalization for Optical Wireless Communications" by Acolaste, Bar-Ness, and Wilson [5] investigates the application of single-carrier frequency-domain equalization to diffuse optical wireless communications and demonstrates its advantages over OFDM in terms of reduced PAPR and improved error rate in the presence of LED nonlinearity. In the paper "Semi-Blind Channel Estimation for IFDMA in Case of Channels with Large Delay Spreads", Sohl and Klein [6] propose a subspace-based channel estimation algorithm which can cope with large delay spreads. In previous work on IFDMA, the number of channel taps that can be estimated was limited to the number of subcarriers per user. The subspace analysis in this paper relaxes this constraint and increases the number of taps that can be estimated. The paper "Channel Frequency response Estimation for MIMO with Systems with Frequency-Domain Equalization " by Yang, Shi, Chew, and Tjhung [7] suggests a training-based channel frequency response (CFR) estimation scheme which is hardware efficient when integrated with and SC-FDE and space time coding (STC) in MIMO Systems. An MSE analysis of this CFR estimation scheme is provided, which considered linear estimators based on both LS and minimum MSE criteria. Also with a given constraint which effectively limits the transmit power of the training signals, the paper investigates the optimal design of training signals under different a priori knowledge of the channel statistics. For the special case of 2 transmit antennas, it was demonstrated that CFR estimation could be implemented in adaptive manner. The paper by Dang, Ruder, Schober and Gerstacker [8], "MMSE Beamforming for SC-FDMA Transmission over MIMO ISI Channels", derives minimum mean squared error beamforming strategies for multi-antenna reception, as well as further modifications to reduce the transmitted peak to average power ratios. The paper by Nishino, Tanahashi, and Ochiai [9], "A Bit Labeling Design for Trellis-Shaped Single-Carrier PSK with PAPR Reduction", investigates application of trellis shaping to reduce the PAPR of band-limited single-carrier PSK signals. The authors demonstrate that the uncoded bit error rate and PAPR reduction capability of trellis shaping is highly dependent on bit labeling. They propose a bit labeling scheme for high-order PSK constellation that can efficiently reduce PAPR while achieving BER performance comparable to that of Gray labeling

Quantitative trait loci conferring grain mineral nutrient concentrations in durum wheat 3 wild emmer wheat RIL population

Mineral nutrient malnutrition, and particularly deficiency in zinc and iron, afflicts over 3 billion people worldwide. Wild emmer wheat, Triticum turgidum ssp. dicoccoides, genepool harbors a rich allelic repertoire for mineral nutrients in the grain. The genetic and physiological basis of grain protein, micronutrients (zinc, iron, copper and manganese) and macronutrients (calcium, magnesium, potassium, phosphorus and sulfur) concentration was studied in tetraploid wheat population of 152 recombinant inbred lines (RILs), derived from a cross between durum wheat (cv. Langdon) and wild emmer (accession G18-16). Wide genetic variation was found among the RILs for all grain minerals, with considerable transgressive effect. A total of 82 QTLs were mapped for 10 minerals with LOD score range of 3.2–16.7. Most QTLs were in favor of the wild allele (50 QTLs). Fourteen pairs of QTLs for the same trait were mapped to seemingly homoeologous positions, reflecting synteny between the A and B genomes. Significant positive correlation was found between grain protein concentration (GPC), Zn, Fe and Cu, which was supported by significant overlap between the respective QTLs, suggesting common physiological and/or genetic factors controlling the concentrations of these mineral nutrients. Few genomic regions (chromosomes 2A, 5A, 6B and 7A) were found to harbor clusters of QTLs for GPC and other nutrients. These identified QTLs may facilitate the use of wild alleles for improving grain nutritional quality of elite wheat cultivars, especially in terms of protein, Zn and Fe

Solar axion search with the CAST experiment

The CAST (CERN Axion Solar Telescope) experiment is searching for solar axions by their conversion into photons inside the magnet pipe of an LHC dipole. The analysis of the data recorded during the first phase of the experiment with vacuum in the magnet pipes has resulted in the most restrictive experimental limit on the coupling constant of axions to photons. In the second phase, CAST is operating with a buffer gas inside the magnet pipes in order to extent the sensitivity of the experiment to higher axion masses. We will present the first results on the $^{4}{\rm He}$ data taking as well as the system upgrades that have been operated in the last year in order to adapt the experiment for the $^{3}{\rm He}$ data taking. Expected sensitivities on the coupling constant of axions to photons will be given for the recent $^{3}{\rm He}$ run just started in March 2008.Comment: Proceedings of the ICHEP 2008 conferenc

Unique and conserved MicroRNAs in wheat chromosome 5D revealed by next-generation sequencing

MicroRNAs are a class of short, non-coding, single-stranded RNAs that act as post-transcriptional regulators in gene expression. miRNA analysis of Triticum aestivum chromosome 5D was performed on 454 GS FLX Titanium sequences of flow sorted chromosome 5D with a total of 3,208,630 good quality reads representing 1.34x and 1.61x coverage of the short (5DS) and long (5DL) arms of the chromosome respectively. In silico and structural analyses revealed a total of 55 miRNAs; 48 and 42 miRNAs were found to be present on 5DL and 5DS respectively, of which 35 were common to both chromosome arms, while 13 miRNAs were specific to 5DL and 7 miRNAs were specific to 5DS. In total, 14 of the predicted miRNAs were identified in wheat for the first time. Representation (the copy number of each miRNA) was also found to be higher in 5DL (1,949) compared to 5DS (1,191). Targets were predicted for each miRNA, while expression analysis gave evidence of expression for 6 out of 55 miRNAs. Occurrences of the same miRNAs were also found in Brachypodium distachyon and Oryza sativa genome sequences to identify syntenic miRNA coding sequences. Based on this analysis, two other miRNAs: miR1133 and miR167 were detected in B. distachyon syntenic region of wheat 5DS. Five of the predicted miRNA coding regions (miR6220, miR5070, miR169, miR5085, miR2118) were experimentally verified to be located to the 5D chromosome and three of them : miR2118, miR169 and miR5085, were shown to be 5D specific. Furthermore miR2118 was shown to be expressed in Chinese Spring adult leaves. miRNA genes identified in this study will expand our understanding of gene regulation in bread wheat

Search for low Energy solar Axions with CAST

We have started the development of a detector system, sensitive to single photons in the eV energy range, to be suitably coupled to one of the CAST magnet ports. This system should open to CAST a window on possible detection of low energy Axion Like Particles emitted by the sun. Preliminary tests have involved a cooled photomultiplier tube coupled to the CAST magnet via a Galileian telescope and a switched 40 m long optical fiber. This system has reached the limit background level of the detector alone in ideal conditions, and two solar tracking runs have been performed with it at CAST. Such a measurement has never been done before with an axion helioscope. We will present results from these runs and briefly discuss future detector developments.Comment: Paper submitted to the proceedings of the "4th Patras Workshop on Axions, WIMPs and WISPs", DESY, Hamburg Site - Germany, 18-21 June 2008. Author affiliations are reported on the title page of the paper. In version 2: 1 affiliation change, 3 references adde

IT adoption of clinical information systems in Austrian and German hospitals: results of a comparative survey with a focus on nursing

<p>Abstract</p> <p>Background</p> <p>IT adoption is a process that is influenced by different external and internal factors. This study aimed</p> <p indent="1">1. to identify similarities and differences in the prevalence of medical and nursing IT systems in Austrian and German hospitals, and</p> <p indent="1">2. to match these findings with characteristics of the two countries, in particular their healthcare system, and with features of the hospitals.</p> <p>Methods</p> <p>In 2007, all acute care hospitals in both countries received questionnaires with identical questions. 12.4% in Germany and 34.6% in Austria responded.</p> <p>Results</p> <p>The surveys revealed a consistent higher usage of nearly all clinical IT systems, especially nursing systems, but also PACS and electronic archiving systems, in Austrian than in German hospitals. These findings correspond with a significantly wider use of standardised nursing terminologies and a higher number of PC workstations on the wards (average 2.1 PCs in Germany, 3.2 PCs in Austria). Despite these differences, Austrian and German hospitals both reported a similar IT budget of 2.6% in Austria and 2.0% in Germany (median).</p> <p>Conclusions</p> <p>Despite the many similarities of the Austrian and German healthcare system there are distinct differences which may have led to a wider use of IT systems in Austrian hospitals. In nursing, the specific legal requirement to document nursing diagnoses in Austria may have stimulated the use of standardised terminologies for nursing diagnoses and the implementation of electronic nursing documentation systems. Other factors which correspond with the wider use of clinical IT systems in Austria are: good infrastructure of medical-technical devices, rigorous organisational changes which had led to leaner processes and to a lower length of stay, and finally a more IT friendly climate. As country size is the most pronounced difference between Germany and Austria it could be that smaller countries, such as Austria, are more ready to translate innovation into practice.</p

MicroRNA-sequence profiling reveals novel osmoregulatory microRNA expression patterns in catadromous eel anguilla marmorata

MicroRNAs (miRNAs) are a class of endogenous small non-coding RNAs that regulate gene expression by post-transcriptional repression of mRNAs. Recently, several miRNAs have been confirmed to execute directly or indirectly osmoregulatory functions in fish via translational control. In order to clarify whether miRNAs play relevant roles in the osmoregulation of Anguilla marmorata, three sRNA libraries of A. marmorata during adjusting to three various salinities were sequenced by Illumina sRNA deep sequencing methods. Totally 11,339,168, 11,958,406 and 12,568,964 clear reads were obtained from 3 different libraries, respectively. Meanwhile, 34 conserved miRNAs and 613 novel miRNAs were identified using the sequence data. MiR-10b-5p, miR-181a, miR-26a-5p, miR-30d and miR-99a-5p were dominantly expressed in eels at three salinities. Totally 29 mature miRNAs were significantly up-regulated, while 72 mature miRNAs were significantly down-regulated in brackish water (10‰ salinity) compared with fresh water (0‰ salinity); 24 mature miRNAs were significantly up-regulated, while 54 mature miRNAs were significantly down-regulated in sea water (25‰ salinity) compared with fresh water. Similarly, 24 mature miRNAs were significantly up-regulated, while 45 mature miRNAs were significantly down-regulated in sea water compared with brackish water. The expression patterns of 12 dominantly expressed miRNAs were analyzed at different time points when the eels transferred from fresh water to brackish water or to sea water. These miRNAs showed differential expression patterns in eels at distinct salinities. Interestingly, miR-122, miR-140-3p and miR-10b-5p demonstrated osmoregulatory effects in certain salinities. In addition, the identification and characterization of differentially expressed miRNAs at different salinities can clarify the osmoregulatory roles of miRNAs, which will shed lights for future studies on osmoregulation in fish