Relationship Between Clinical Competence of Undergraduate Nursing Students and Their Understanding of Children.

The objective of this study is to examine the relationship between clinical competence of undergraduate nursing students and their understanding of children. Study methods consisted of a questionnaire survey that used scales developed to measure nursing students' clinical competence and understanding of children. The study was conducted with the approval of the ethics committee of Nara Medical University. Two hundred and fifty-seven nursing students participated in this survey, and of these, two hundred and thirty-three were subject to analysis. Of the nursing students surveyed, 183 (79%) reported having experience with children, and there was no significant difference in experience with children between students in different years of study.Nursing students' experience with children involved playing with them, helping them with learning or playing sports, and raising them. The children they had experience with were pre-school and school-aged children. The study found a correlation between the nursing students' understanding of children and clinical competence. In addition, there was a significant relationship between nursing students' experience with children and their understanding of children. There was no significant difference in third-year students' understanding of children as compared to that of fourth-year students, who had completed practical training. There was,however, a significant difference in clinical competence between these two groups. These results indicate that nursing students' understanding of children is connected to their clinical competence, and that practical nursing training is necessary to increase the clinical competence of nursing students. In addition, educational intervention that deepens nursing students' understanding of sick children is important to improving clinical competence

Physiological variation among Tricholoma matsutake isolates generated from basidiospores obtained from one basidioma

ArticleMycoscience. 60(2): 102-109. (2019)journal articl

Odor of ar-turmerone, α-curcumene, and limonene derivatives depending on their chirality

The combination of many kinds of odor molecules produces the characteristic aromas of natural odor materials. We found that the odors of such materials were expressed by a set of constituents with similar structures by the investigations of the aroma profiles of several incenses [1]. Recent studies about the olfactory mechanism show that several olfactory receptors interact with one odorant molecule with different intensities and one olfactory receptor responds to different odorant molecules with similar structures. The consequences of this mechanism are that the interactions of several constituents with similar structures are important for the aroma profile. We investigated the relationship between odorant structure and the aroma characteristics of odor molecules focusing on their chirality.                Stereoisomers of ar-turmerone, α-curcumene, and limonene (Fig. 1) have been reported to have different odors. We synthesized a series of derivatives of these compounds to get insight into their structural similarities, especially those relating to the chirality and its interaction with olfactory receptors. We investigated the structure-odor relationships and found important structural factors (molecular skeleton, groups containing oxygen, isoprene moiety) for the onset of specific odors

Chick-computer interaction using sounds

The 11th International Symposium on Adaptive Motion of Animals and Machines. Kobe University, Japan. 2023-06-06/09. Adaptive Motion of Animals and Machines Organizing Committee.Poster Session P4

Effect of cyclic bis(3′–5′)diguanylic acid and its analogs on bacterial biofilm formation

Cyclic bis(3′–5′)diguanylic acid (cyclic-di-GMP) functions as a second messenger in diverse species of bacteria to trigger wide-ranging physiological changes. We measured cyclic-di-GMP and its structural analogs such as cyclic bis(3′–5′)guanylic/adenylic acid (cyclic-GpAp), cyclic bis(3′–5′)guanylic/inosinic acid (cyclic-GpIp) and monophosphorothioic acid of cyclic-di-GMP (cyclic-GpGps) for effects on the biofilm formation of Staphylococcus aureus and Pseudomonas aeruginosa. We constructed a knockout mutant of SA0701, which is a GGDEF motif protein relevant to diguanylate cyclase from S. aureus 2507. We confirmed that the biofilm formation of this mutant (MS2507ΔSA0701) was reduced. Cyclic-di-GMP corresponding to physiological intracellular levels given in the culture recovered the biofilm formation of MS2507ΔSA0701, whereas its analogs did not, indicating that unlike a previous suggestion, cyclic-di-GMP was involved in the positive regulation of the biofilm formation of S. aureus and its action was structurally specific. At a high concentration (200 μM), cyclic-di-GMP and its analogs showed suppression effects on the biofilm formation of S. aureus and P. aeruginosa, and according to the quantification study using costat analysis, the suppression potential was in the order of cyclic-di-GMP, cyclic-GpGps, cyclic-GpAp and cyclic-GpIp, suggesting that the suppression effect was not strictly specific and the change of base structure quantitatively affected the suppression activity

Integration and Diffusion in Sustainable Development Goals: Learning from the Past, Looking into the Future

One of the next major challenges for research and policy on sustainability is setting the post-2015 Development Agenda. This challenge arises as a direct result of the formal ending of the Millennium Development Goals (MDGs) in 2015 and as an outcome of the 2012 United Nations Conference on Sustainable Development (Rio+20). The post-2015 Development Agenda is expected to include two agendas: one on human well-being to advance the MDG targets and the other on planetary well-being, which requires a safe "operating space" within the Earth\u27s life-support system. In contrast to the MDGs, the Sustainable Development Goals (SDGs) are meant to apply to both developing and developed countries and create a space for development within the stable functioning of the Earth\u27s systems. However, what might this all look like? For answers, this paper reviews the achievements and reflections of the MDGs to date and identifies new challenges entailed in the shift of development goals from "millennium" to "sustainable". While most of the existing studies look at these two sets of issues separately, combining the two reveals two important features of the SDGs. First, SDGs need to integrate both human and planetary well-being in a goal, and second, goals, or sub-goals, need to be formulated at multiple levels, from global to local levels. While the MDGs represented no integrated goals, some of the existing proposals on SDGs include integrated goals. However, our analysis has shown that they do not present the vertical diffusion of goals. Considering both integration and diffusion in the architecture of SDGs is a remaining task

Correction: Kanie, N., et al. Integration and Diffusion in Sustainable Development Goals: Learning from the Past, Looking into the Future. Sustainability 2014, 6, 1761?1775

The authors wish to make the following correction, due to a typographical error, to this paper [1]. On page 1761, the author name “Shunsuke Mangagi” should be “Shunsuke Managi”. [...

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016)

Background and purposeThe Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), a Japanese-specific set of clinical practice guidelines for sepsis and septic shock created jointly by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine, was first released in February 2017 and published in the Journal of JSICM, [2017; Volume 24 (supplement 2)] https://doi.org/10.3918/jsicm.24S0001 and Journal of Japanese Association for Acute Medicine [2017; Volume 28, (supplement 1)] http://onlinelibrary.wiley.com/doi/10.1002/jja2.2017.28.issue-S1/issuetoc.This abridged English edition of the J-SSCG 2016 was produced with permission from the Japanese Association of Acute Medicine and the Japanese Society for Intensive Care Medicine.MethodsMembers of the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine were selected and organized into 19 committee members and 52 working group members. The guidelines were prepared in accordance with the Medical Information Network Distribution Service (Minds) creation procedures. The Academic Guidelines Promotion Team was organized to oversee and provide academic support to the respective activities allocated to each Guideline Creation Team. To improve quality assurance and workflow transparency, a mutual peer review system was established, and discussions within each team were open to the public. Public comments were collected once after the initial formulation of a clinical question (CQ) and twice during the review of the final draft. Recommendations were determined to have been adopted after obtaining support from a two-thirds (> 66.6%) majority vote of each of the 19 committee members.ResultsA total of 87 CQs were selected among 19 clinical areas, including pediatric topics and several other important areas not covered in the first edition of the Japanese guidelines (J-SSCG 2012). The approval rate obtained through committee voting, in addition to ratings of the strengths of the recommendation, and its supporting evidence were also added to each recommendation statement. We conducted meta-analyses for 29 CQs. Thirty-seven CQs contained recommendations in the form of an expert consensus due to insufficient evidence. No recommendations were provided for five CQs.ConclusionsBased on the evidence gathered, we were able to formulate Japanese-specific clinical practice guidelines that are tailored to the Japanese context in a highly transparent manner. These guidelines can easily be used not only by specialists, but also by non-specialists, general clinicians, nurses, pharmacists, clinical engineers, and other healthcare professionals