Jubiläum in Kiel: Das 10. Kieler Insolvenz-Symposium

In Kiel fand am 23.5. und 24. 5. 2014 das mittlerweile 10. Kieler Insolvenz-Symposium statt. Zur Jubiläumsveranstal- tung erschienen weit über 170 Teilnehmer, um sich der Dis- kussion und dem Austausch zu aktuellen Problemen und Themen des Insolvenzrechts zu stellen. Die Veranstaltung zeichnet sich durch seine überregionale Bedeutung aus und stellt die wohl größte juristische Veranstaltung seiner Art in Schleswig-Holstein dar. Neben der großen fachlichen Bedeutung ist das Kernziel der Veranstaltung, Doktoran- den und Studierende mit den Praktikern aus der Fachwelt des Insolvenzrechts zusammenzuführen, um sich fach- lich auszutauschen. In diesem Jahr lagen dieSchwerpunkte der Veranstaltung überwiegend in den Entwicklungen des Vergütungsrechts und den anstehenden Reformvor- haben

Iron cycling and stable Fe isotope fractionation in Antarctic shelf sediments, King George Island

Iron (Fe) fluxes from reducing sediments and subglacial environments are potential sources of bioavailable Fe into the Southern Ocean. Stable Fe isotopes (δ56Fe ) are considered a proxy for Fe sources and reaction pathways, but respective data are scarce and Fe cycling in complex natural environments is not understood sufficiently to constrain respective δ56Fe “endmembers” for different types of sediments, environmental conditions, and biogeochemical processes. We present δ56Fe data from pore waters and sequentially extracted sedimentary Fe phases of two contrasting sites in Potter Cove (King George Island, Antarctic Peninsula), a bay that is affected by fast glacier retreat. Sediments close to the glacier front contain more easily reducible Fe oxides and pyrite and show a broader ferruginous zone, compared to sediments close to the icefree coast, where surficial oxic meltwater streams discharge into the bay. Pyrite in sediments close to the glacier front predominantly derives from eroded bedrock. For the high amount of easily reducible Fe oxides proximal to the glacier we suggest mainly subglacial sources, where Fe liberation from comminuted material beneath the glacier is coupled to biogeochemical weathering processes (likely pyrite oxidation or dissimilatory iron reduction, DIR). Our strongest argument for a subglacial source of the highly reactive Fe pool in sediments close to the glacier front is its predominantly negative δ56Fe signature that remains constant over the whole ferruginous zone. This implies in situ DIR does not significantly alter the stable Fe isotope composition of the accumulated Fe oxides. The nonetheless overall light δ56Fe signature of easily reducible Fe oxides suggests pre-depositional microbial cycling as it occurs in potentially anoxic subglacial environments. The strongest 56Fe-depletion in pore water and most reactive Fe oxides was observed in sediments influenced by oxic meltwater discharge. The respective site showed a condensed redox zonation and a pore water δ56Fe profile typical for in-situ Fe cycling. We demonstrate that the potential of pore water δ56Fe as a proxy for benthic Fe fluxes is not straight-forward due to its large variability in marine shelf sediments at small spatial scales (- 2.4‰ at the site proximal to oxic meltwater discharge vs. -0.9‰ at the site proximal to the marine glacier terminus, both at 2 cm sediment depth). The controlling factors are multifold and include the amount and reactivity of reducible Fe oxides and organic matter, the isotopic composition of the primary and secondary ferric substrates, sedimentation rates, and physical reworking (bioturbation, ice scraping). The application of δ56Fe geochemistry may prove valuable in investigating biogeochemical weathering and Fe cycling in subglacial environments. This requires, however (similarly to the use of δ56Fe for the quantification of benthic fluxes), that the spatial and temporal variability of the isotopic endmember is known and accounted for. Since geochemical data from subglacial environments are very limited, further studies are needed in order to sufficiently assess Fe cycling and fractionation at glacier beds and the composition of discharges from those areas

Cluster Forschungsdaten – Kooperative Forschungsservices in Österreich

Der Cluster Forschungsdaten spielt eine entscheidende Rolle bei der Koordinierung des Zusammenspiels von Forschungsinformationssystemen, Forschungsdatenmanagement und digitalen Technologien/Infrastrukturen. Ein besonderer Fokus liegt dabei auf der Identifizierung von Synergien und Potenzialen für eine ressourcenoptimierte Zusammenarbeit zwischen den verschiedenen Forschungseinrichtungen des Landes. Darüber hinaus strebt der Cluster Forschungsdaten eine einheitliche Präsenz bei der Entwicklung und Zusammenführung von forschungsunterstützenden Services auf allen Ebenen des Forschungsdaten- und Forschungsinformations-Managements an. Dies gewährleistet eine effiziente und kohärente Gestaltung der Prozesse

Zukunftsweisender Forschungssupport: Das Digitalisierungsprojekt RIS Synergy

Das Projekt RIS Synergy (2020–2024) verfolgt institutionsübergreifend wesentliche Aspekte digitaler Transformation: Im Teilprojekt Schnittstellen und Standards werden standardisierte Austauschmöglichkeiten für Systeme von Förderorganisationen, Forschungsstätten und der öffentlichen Verwaltung geschaffen. Das Teilprojekt Konzeptstudie Forschungsportal befasst sich mit Rahmenbedingungen und Anforderungen eines nationalen Forschungsportals. RIS Synergy schafft Entlastung und Sichtbarkeit für den Wissenschaftsbetrieb durch die Umsetzung von Standards, die Digitalisierung von Services sowie die Vernetzung von Expertise. Der vorliegende Artikel gibt Einblick in Herangehensweise und Best Practices aus dem Projekt

Quantum tunneling and stochastic resonance

Stochastic resonance (SR) occurs in nonlinear dynamical systems when the response to a weak coherent input is enhanced by the presence of noise. While classical SR presently is an intensely studied phenomenon, the role of quantum fluctuations has only started to be explored. We study SR in the temperature range where quantum tunneling corrections to the classical rate of activation are relevant. For a particle subject to moderate-to-large friction, we show that the semiclassical SR can be enhanced considerably by quantum fluctuations, as compared to the predictions of a classical analysis

Quantum tunneling and stochastic resonance

Stochastic resonance (SR) occurs in nonlinear dynamical systems when the response to a weak coherent input is enhanced by the presence of noise. While classical SR presently is an intensely studied phenomenon, the role of quantum fluctuations has only started to be explored. We study SR in the temperature range where quantum tunneling corrections to the classical rate of activation are relevant. For a particle subject to moderate-to-large friction, we show that the semiclassical SR can be enhanced considerably by quantum fluctuations, as compared to the predictions of a classical analysis

Quantum tunneling and stochastic resonance

Stochastic resonance (SR) occurs in nonlinear dynamical systems when the response to a weak coherent input is enhanced by the presence of noise. While classical SR presently is an intensely studied phenomenon, the role of quantum fluctuations has only started to be explored. We study SR in the temperature range where quantum tunneling corrections to the classical rate of activation are relevant. For a particle subject to moderate-to-large friction, we show that the semiclassical SR can be enhanced considerably by quantum fluctuations, as compared to the predictions of a classical analysis

A Case of Linear Porokeratosis Superimposed on Disseminated Superficial Actinic Porokeratosis

We present a female patient with linear porokeratosis of her right arm since childhood. At the age of 67 years she additionally developed disseminated superficial actinic porokeratosis (DSAP) involving both lower legs. This uncommon coexistence of two different types of porokeratosis fulfils the clinical criteria of a type 2 segmental manifestation of an autosomal dominant skin disorder, being superimposed on the ordinary nonsegmental lesions and reflecting loss of heterozygosity that occurred at an early developmental stage. In DSAP molecular evidence of this concept is so far lacking, but such proof has already been provided in several other autosomal dominant skin disorders. Molecular analysis of cases of type 2 segmental involvement may help elucidate the genetic defect causing DSAP

Synthesis of tumor-associated MUC1-glycopeptides and their multivalent presentation by functionalized gold colloids

The mucin MUC1 is a glycoprotein involved in fundamental biological processes, which can be found over-expressed and with a distinctly altered glycan pattern on epithelial tumor cells; thus it is a promising target structure in the quest for effective carbohydrate-based cancer vaccines and immunotherapeutics. Natural glycopeptide antigens indicate only a low immunogenicity and a T-cell independent immune response; however, this major drawback can be overcome by coupling of glycopeptide antigens multivalently to immunostimulating carrier platforms. In particular, gold nanoparticles are well suited as templates for the multivalent presentation of glycopeptide antigens, due to their remarkably high surface-to-volume ratio in combination with their high biostability. In this work the synthesis of novel MUC1-glycopeptide antigens and their coupling to gold nanoparticles of different sizes are presented. In addition, the development of a new dot-blot immunoassay to test the potential antigen-antibody binding is introduced

Identification of mineralocorticoid receptor target genes in the mouse hippocampus

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