5,940 research outputs found

    ā€˜Knit ā€œnā€ natterā€™: A feminist methodological assessment of using creative ā€˜womenā€™s workā€™ in focus groups

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    This article outlines the methodological innovations generated in a study of knitting and femininity in Britain. The study utilised ā€˜knit ā€œnā€ natterā€™ focus groups during which female participants were encouraged to knit and talk. The research design encompassed a traditionally undervalued form of domestic ā€˜womenā€™s workā€™ to recognise the creative skills of female practitioners. ā€˜Knit ā€œnā€ natterā€™ is a fruitful feminist research method in relation to its capitalisation on female participantsā€™ creativity, its disruption of expertise and its feminisation of academic space. The method challenges patriarchal conventions of knowledge production and gendered power relations in research, but it also reproduces problematic constructions of gender, which are acknowledged. The study contributes to a growing body of work on creative participatory methods and finds that the ā€˜knit ā€œnā€ natterā€™ format has utility beyond investigations of crafting and may be used productively in other contexts where in-depth research with women is desirable

    The association of HBV core promoter double mutations (A1762T and G1764A) with viral load differs between HBeAg positive and anti-HBe positive individuals: A longitudinal analysis

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    Background/Aims: Although there have been a few reports regarding the effect of basal core promoter (BCP) double mutations (A1762T and G1764A) on hepatitis B viral loads, the association remains uncertain. We aim to determine the association after controlling for HBeAg - a strong confounding factor.Methods: We selected randomly 190 individuals from a Chinese cohort of 2258 subjects for cross-sectional analysis and 56 of the 190 for longitudinal analysis of viral loads.Results: In multivariable analysis of the cross-sectional data, BCP double mutations are significantly associated with lower viral loads in HBeAg positive subjects but no difference was found in anti-HBe positive subjects. Triple mutations at nucleotide (nt) 1753, 1762 and 1764 and mutations between nt 1809 and 1817, precore stop mutation (nt 1896) and genotype are not associated with viral loads in either HBeAg or anti-HBe positive subjects. Analysis of the longitudinal data yielded similar results to the cross-sectional data. Viral loads differ significantly between individuals infected with wild-type and BCP double mutations prior to HBeAg seroconversion but this difference is lost after seroconversion.Conclusions: BCP double mutations are associated with lower viral loads in HBeAg positive individuals but have no effect on the viral loads of anti-HBe positive individuals. (C) 2008 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved

    Public health and economic costs of investigating a suspected outbreak of Legionnaires' disease.

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    This paper provides one of the first assessments of the burden of both the public health investigation and the economic costs associated with an apparent outbreak of Legionnaires' disease (LD) in South East London. In addition to epidemiological, microbiological and environmental investigations, we collected data on the staff time and resources committed by the 11 main organizations responsible for managing the outbreak. Of the overall estimated costs of 455,856 pounds, only 14% (64,264 pounds) was spent on investigation and control of the outbreak compared with 86% (391,592 pounds) spent on the hospital treatment of the patients. The time and money spent on public health services in this investigation appear to represent good value for money considering the potential costs of a major outbreak, including the high case-fatality rate in LD generally and the high health-care costs. Further research is needed to determine optimum strategies for the cost-effective use of health system resources in investigations of LD. Whether the threshold for investigation of cases should be based on observed incidence rates or the cost-effectiveness of investigations, or both, should be debated further

    "Grandma never knit like this": Reclaiming older women's knitting practices from discourses of new craft in Britain

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    New discourses of craft construct knitting as young, hip, socially networked and politically conscious and the experiences of knitters who do not fit into this formulation are marginalised. 7.3 million people in Britain knit; the vast majority are women in their mid-thirties and older. Yet popular media accounts of ā€˜new knittingā€™ mobilise the derogatory figure of the ā€˜grandmaā€™ to repudiate knitters who are seen not to properly instantiate contemporary femininity. Although this derision accrues particularly to older women, knitters of all ages can be similarly dismissed. Knitting is thus a site of struggle around new formations of gender in postfeminist culture in which some women fall short. This study uses original qualitative data from focus groups with 15 adult knitters in North-west England and North Wales to give voice to women who do not identify with ā€˜new knittingā€™ practices and primarily pursue their hobby in more conventional contexts. The article finds that traditional domestic craft practices continue to play a significant role, particularly in older womenā€™s leisure, and that ā€˜new knittingā€™ is alienating for some practitioners. While the article concludes that twenty-first century discourses of craft have devalued established knitting practices, it also indicates that these are useful sources of critique of hipster capitalist postfeminist culture

    'Knit "n" natterā€™ : A feminist methodological assessment of using creative ā€˜womenā€™s workā€™ in focus groups

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    This article outlines the methodological innovations generated in a study of knitting and femininity in Britain. The study utilised ā€˜knit ā€œnā€ natterā€™ focus groups during which female participants were encouraged to knit and talk. The research design encompassed a traditionally undervalued form of domestic ā€˜womenā€™s workā€™ to recognise the creative skills of female practitioners. ā€˜Knit ā€œnā€ natterā€™ is a fruitful feminist research method in relation to its capitalisation on female participantsā€™ creativity, its disruption of expertise and its feminisation of academic space. The method challenges patriarchal conventions of knowledge production and gendered power relations in research, but it also reproduces problematic constructions of gender, which are acknowledged. The study contributes to a growing body of work on creative participatory methods and finds that the ā€˜knit ā€œnā€ natterā€™ format has utility beyond investigations of crafting and may be used productively in other contexts where in-depth research with women is desirable

    Growth differentiation factor 9: bone morphogenetic protein 15 synergism and the potential involvement of heterodimerization

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    LetterDavid G. Mottershead, Craig A. Harrison, Thomas D. Mueller, Peter G. Stanton, Robert B. Gilchrist and Kenneth P. McNatt

    Open-source bandstructure models of interdiffusion, impurity and exciton states for the QWWAD v1.4 simulation suite

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    The vast majority of high-quality software for simulating semiconductor nanostructures (e.g., [1]) is supplied under a proprietary license and its source code cannot be studied, modified or redistributed by its users. The open-source project, Quantum Wells, Wires and Dots (QWWAD) [2] is a free, non-commercial community-focused resource, which accompanies the new 4th edition of the eponymous textbook [3]. Previously described features in QWWAD include numerical Schrodinger/Poisson solvers in generic 1D potentials [e.g., Fig. 1(a)], quasi-analytical and empirical pseudopotential calculations of the band-structure in quantum wires and dots, and scattering calculations for interactions with impurities, phonons, interface roughness, alloy disorder and carrierā€“carrier processes. We describe new tools, included in the latest release (QWWAD v1.4), for modelling the perturbed quantum-confined states within 2D heterostructures resulting from interdiffusion, impurities and excitonic contribution
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