HISTORIC AND RECENT WINTER SANDHILL CRANE DISTRIBUTION IN CALIFORNIA

Understanding the geographic distribution and long-term dynamics of winter foraging areas and night roost sites of sandhill cranes (Grus canadensis) is important to their conservation and management. We studied sandhill crane distribution in California’s Central Valley from December 2012 through February 2013. We mapped observed flock and night roost locations. Flock locations occurred between Tehama County in the north and Kern County in the south. Flocks were concentrated in the northern Sacramento Valley, the Sacramento-San Joaquin Delta, the northern San Joaquin Valley south of Tracy to Mendota (including the lower Stanislaus and Tuolumne River floodplains and the Grasslands Region), and the southern San Joaquin Valley in the vicinity of Pixley in Tulare County. We also reviewed records of historic occurrences of cranes in California to interpret the importance of our flock and night roost locations. Although cranes wintered in the Los Angeles, San Diego, and San Francisco Bay metropolitan areas in the 19th and early 20th centuries, they no longer occur in significant numbers in these areas due to widespread habitat loss. Three additional areas which were used in the mid-20th century have apparently been abandoned or are being used only infrequently: the Red Bluff area (along the Sacramento River between Red Bluff and Anderson, Tehama County), the Goose Lake area (Kern County), and the Carrizo Plain (San Luis Obispo County). The primary cause of site abandonment at these sites is loss of suitable foraging habitat (small grain crops). With the exception of the Southern San Joaquin region, crane winter range has expanded in the Central Valley since the 1960s. Range expansion has principally been due to expansion of public wildlife refuges and private sanctuaries, plus improvements in their management (including reductions in hunting disturbance). To improve habitat conditions for cranes across their Central Valley wintering range, we recommend that management be focused on protection, enhancement, and creation of crane habitat complexes, each of which should contain 1 or more roost sites surrounded by sufficient well-managed foraging habitat. The following conservation strategies (listed in order of priority) should be implemented for each major crane wintering region: 1) protect existing, unprotected roost sites by fee-title acquisition or conservation easements (prioritize among sites according to their importance to greater sandhill cranes; G. c. tabida); 2) protect foraging landscapes around existing roosts, primarily through easements restricting development and crop types that are incompatible to cranes; 3) enhance food availability within those landscapes by improving foraging conditions on conservation lands and providing annual incentives for improvements on private lands; and 4) create additional protected roost sites toward the edge of their existing range where birds can access additional foraging areas

Mostra de ciências na Operação Rondon UEPG: experiência multiprofissional de rondonistas em Ibaiti – Paraná

Trabalho apresentado no II Congresso Nacional do PROJETO RONDON, realizado em Florianópolis, SC, no período de 23 a 25 de setembro de 2015 - Universidade Federal de Santa Catarina.A Operação Rondon UEPG é um projeto de integração social envolvendo participação de universitários voluntários em busca de soluções para o desenvolvimento sustentável em comunidades paranaenses. A Operação ocorreu em seis municípios do Paraná, no período de 19 a 29 de julho de 2015. Este é um relato de experiência de três rondonistas estudantes dos cursos de Química Licenciatura (UNIOESTE), Farmácia (UEPG) e Residência Multiprofissional em Saúde do Idoso – Cirurgiã Dentista (UEPG), participantes da Operação Rondon UEPG no município de Ibaiti – PR. O relato trata da realização da oficina intitulada “Mostra de Ciências”, com o intuito de aproximar os alunos dos processos relacionados as ciências com atividades experimentais voltadas à área da química, criando problemas reais que permitiram a contextualização e o estímulo de questionamentos de investigação. A oficina foi realizada em três colégios de Ibaiti: Colégio Estadual Aldo Dallago, Colégio Estadual Martins de Mello e Centro Estadual de Educação Profissional; atingindo cerca de 260 alunos do ensino fundamental ao médio. A Mostra de Ciências teve como foco principal relacionar os conceitos de acidez e basicidade com o cotidiano dos alunos. Com a finalidade de verificar os conhecimentos prévios dos estudantes em relação aos conceitos de acidez e basicidade, alguns produtos utilizados de forma rotineira (vinagre, suco de limão, água sanitária, solução de bicarbonato de sódio e sabão em pó) foram apresentados e questionamentos sobre as propriedades destes produtos foram realizados. Na sequência, testou-se a acidez e basicidades destes produtos utilizando um indicador ácido-base caseiro de beterraba e discutiu-se os conceitos químicos envolvidos. Também foi realizado o experimento da bexiga que se trata da reação ácido-base do vinagre com o bicarbonato de sódio. Durante a Mostra de Ciências foi possível relacionar a química com áreas da saúde como farmácia e odontologia. Explicou-se sobre a relação da mudança de pH da saliva com doenças bucais, demonstrando a importância de se realizar a higiene bucal. Observou-se que a experimentação proporcionou o interesse dos alunos, que puderam perceber que atividades simples do cotidiano estão relacionados com a ciência. Para os rondonistas, a experiência da oficina foi de suma importância visto que estes conseguiram compartilhar e construir conhecimentos de forma multiprofissional, relacionando as áreas da química, farmácia e odontologia

Intervenções de enfermagem nas intercorrências do tratamento hemodialítico

Estudo quantitativo com objetivo de identificar as intercorrências e as ações de enfermagem durante o tratamento hemodialítico de pacientes portadores de insuficiência renal crônica. A amostra foi constituída por 30 pacientes. Os dados foram coletados através dos prontuários e de observação direta das sessões de hemodiálise dos participantes, perfazendo um total de 240 sessões. A idade dos pacientes variou de 21-89 anos, 22 (73,33%) do sexo masculino e 8 (26,67%) do sexo feminino. Todos os pacientes apresentaram patologias prévias, 19 (63,33%) Hipertensão Arterial, 8 (26,67%) doenças renais e 1 (3,33%) Diabetes Mellitus. Foram observadas 66 intercorrências dentre as quais, em ordem decrescente, hipotensão, cefaléia, hipertensão, náusea-vômito, dor torácica-lombar, bradicardia, cólica intestinal e febre-calafrios. Dentre as ações de enfermagem, as mais realizadas foram administração de medicação e verificação de sinais vitais. Pode-se perceber que a enfermagem conhece e atua corretamente nas intercorrências e que cada atuação depende da gravidade da situação

Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis

Oxidation-associated malondialdehyde (MDA) modification of proteins can generate immunogenic neo-epitopes that are recognized by autoantibodies. In health, IgM antibodies to MDA-adducts are part of the natural antibody pool, while elevated levels of IgG anti-MDA are associated with inflammatory conditions. Yet, in human autoimmune disease IgG anti-MDA responses have not been well characterized and their potential contribution to disease pathogenesis is not known. Here, we investigate MDA-modifications and anti-MDA-modified protein autoreactivity in rheumatoid arthritis (RA). While RA is primarily associated with autoreactivity to citrullinated antigens, we also observed increases in serum IgG anti-MDA in RA patients compared to controls. IgG anti-MDA levels significantly correlated with disease activity by DAS28-ESR and serum TNF-alpha, IL-6, and CRP. Mass spectrometry analysis of RA synovial tissue identified MDA-modified proteins and revealed shared peptides between MDA-modified and citrullinated actin and vimentin. Furthermore, anti-MDA autoreactivity among synovial B cells was discovered when investigating recombinant monoclonal antibodies (mAbs) cloned from single B cells. Several clones were highly specific for MDA-modification with no cross-reactivity to other antigen modifications. The mAbs recognized MDA-adducts in a variety of proteins. Interestingly, the most reactive clone, originated from an IgG1-bearing memory B cell, was encoded by germline variable genes, and showed similarity to previously reported natural IgM. Other anti-MDA clones display somatic hypermutations and lower reactivity. These anti-MDA antibodies had significant in vitro functional properties and induced enhanced osteoclastogenesis, while the natural antibody related high-reactivity clone did not. We postulate that these may represent distinctly different facets of anti-MDA autoreactive responses

Emotional Labor in Mathematics: Reflections on Mathematical Communities, Mentoring Structures, and EDGE

Terms such as "affective labor" and "emotional labor" pepper feminist critiques of the workplace. Though there are theoretical nuances between the two phrases, both kinds of labor involve the management of emotions; some acts associated with these constructs involve caring, listening, comforting, reassuring, and smiling. In this article I explore the different ways academic mathematicians are called to provide emotional labor in the discipline, thereby illuminating a rarely visible component of a mathematical life in the academy. Underlying this work is my contention that a conceptualization of labor involved in managing emotions is of value to the project of understanding the character, values, and boundaries of such a life. In order to investigate the various dimensions of emotional labor in the context of academic mathematics, I extend the basic framework of Morris and Feldman [33] and then apply this extended framework to the mathematical sciences. Other researchers have mainly focused on the negative effects of emotional labor on a laborer's physical, emotional, and mental health, and several examples in this article align with this framing. However, at the end of the article, I argue that mathematical communities and mentoring structures such as EDGE help diminish some of the negative aspects of emotional labor while also accentuating the positives.Comment: Revised version to appear in the upcoming volume A Celebration of EDGE, edited by Sarah Bryant, Amy Buchmann, Susan D'Agostino, Michelle Craddock Guinn, and Leona Harri

Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis

Impaired proinsulin-to-insulin processing in pancreatic β-cells is a key defective step in both type 1 diabetes and type 2 diabetes (T2D) (refs. $^{1}$$^{,}$$^{2}$), but the mechanisms involved remain to be defined. Altered metabolism of sphingolipids (SLs) has been linked to development of obesity, type 1 diabetes and T2D (refs. $^{3-8}$); nonetheless, the role of specific SL species in β-cell function and demise is unclear. Here we define the lipid signature of T2D-associated β-cell failure, including an imbalance of specific very-long-chain SLs and long-chain SLs. β-cell-specific ablation of CerS2, the enzyme necessary for generation of very-long-chain SLs, selectively reduces insulin content, impairs insulin secretion and disturbs systemic glucose tolerance in multiple complementary models. In contrast, ablation of long-chain-SL-synthesizing enzymes has no effect on insulin content. By quantitatively defining the SL-protein interactome, we reveal that CerS2 ablation affects SL binding to several endoplasmic reticulum-Golgi transport proteins, including Tmed2, which we define as an endogenous regulator of the essential proinsulin processing enzyme Pcsk1. Our study uncovers roles for specific SL subtypes and SL-binding proteins in β-cell function and T2D-associated β-cell failure

HISTORIC AND RECENT WINTER SANDHILL CRANE DISTRIBUTION IN CALIFORNIA

Understanding the geographic distribution and long-term dynamics of winter foraging areas and night roost sites of sandhill cranes (Grus canadensis) is important to their conservation and management. We studied sandhill crane distribution in California’s Central Valley from December 2012 through February 2013. We mapped observed flock and night roost locations. Flock locations occurred between Tehama County in the north and Kern County in the south. Flocks were concentrated in the northern Sacramento Valley, the Sacramento-San Joaquin Delta, the northern San Joaquin Valley south of Tracy to Mendota (including the lower Stanislaus and Tuolumne River floodplains and the Grasslands Region), and the southern San Joaquin Valley in the vicinity of Pixley in Tulare County. We also reviewed records of historic occurrences of cranes in California to interpret the importance of our flock and night roost locations. Although cranes wintered in the Los Angeles, San Diego, and San Francisco Bay metropolitan areas in the 19th and early 20th centuries, they no longer occur in significant numbers in these areas due to widespread habitat loss. Three additional areas which were used in the mid-20th century have apparently been abandoned or are being used only infrequently: the Red Bluff area (along the Sacramento River between Red Bluff and Anderson, Tehama County), the Goose Lake area (Kern County), and the Carrizo Plain (San Luis Obispo County). The primary cause of site abandonment at these sites is loss of suitable foraging habitat (small grain crops). With the exception of the Southern San Joaquin region, crane winter range has expanded in the Central Valley since the 1960s. Range expansion has principally been due to expansion of public wildlife refuges and private sanctuaries, plus improvements in their management (including reductions in hunting disturbance). To improve habitat conditions for cranes across their Central Valley wintering range, we recommend that management be focused on protection, enhancement, and creation of crane habitat complexes, each of which should contain 1 or more roost sites surrounded by sufficient well-managed foraging habitat. The following conservation strategies (listed in order of priority) should be implemented for each major crane wintering region: 1) protect existing, unprotected roost sites by fee-title acquisition or conservation easements (prioritize among sites according to their importance to greater sandhill cranes; G. c. tabida); 2) protect foraging landscapes around existing roosts, primarily through easements restricting development and crop types that are incompatible to cranes; 3) enhance food availability within those landscapes by improving foraging conditions on conservation lands and providing annual incentives for improvements on private lands; and 4) create additional protected roost sites toward the edge of their existing range where birds can access additional foraging areas

Collective subjects, emancipatory cultures and political transformation

What can today's politics and cultures teach us about subjectivity? Can post-deconstructive theorisations of subjectivity retain or even widen the spaces in which subjects that are no longer metaphysical or humanist might cooperate to construct new emancipatory struggles? Guided by these questions, this special issue explores the ways in which subjectivity is being constituted and contested in the early twenty-first century: it examines radical traditions in the light of their impact on contemporary subject formation and the challenges and opportunities that the theorisation of subjectivity faces in the light of globalised cultural exchanges and cross-disciplinary fertilisations, a dominant neoliberal politics and media, and emerging grassroots movements. Throughout, the question of what it means to be a political subject in the early twenty-first century is explored with reference to a determinedly leftist tradition of anti-capitalism, anti-imperialism, anti-racism and anti-sexism

Gestaltung von Zu- und Übergängen zu Angeboten der Hochschulweiterbildung

Diese Handreichung basiert auf einem Workshop zur Gestaltung von Zu- und Übergängen zu Angeboten der Hochschulweiterbildung, der am 9. September 2014 an der Humboldt-Universität zu Berlin stattgefunden hat. Sie gibt einen Eindruck des aktuellen Stands von Ansätzen zur Gestaltung von Zu- und Übergängen zu Angeboten des Lebenslangen Lernens an deutschen Hochschulen und liefert Hinweise für die Konzeption und Organisation von Angeboten. Zudem kann sie als Grundlage dazu dienen, den eigenen Arbeitsstand zu reflektieren und einzuordnen. Diese Publikation ist im Rahmen der wissenschaftlichen Begleitung des Bund-Länder-Wettbewerbs „Aufstieg durch Bildung: offene Hochschulen“ entstanden. (Hrsg.