1,156 research outputs found
Drug-susceptibility Patterns of Mycobacterium tuberculosis in Mpumalanga Province, South Africa: Possible Guiding Design of Retreatment Regimen
Multidrug-resistant tuberculosis (MDR-TB) has been a cause of concern in both developed and developing countries. The prevalence of drug resistance in Mycobacterium tuberculosis (MTB) isolates (n=692) from Mpumalanga province was assessed. In total, 692 (64%) MTB strains from cases with pulmonary TB were tested for susceptibility against rifampicin, isoniazid, ethambutol, and streptomycin using the MGIT 960 instrument. Two hundred and nine (30.2%) strains were resistant to one or more drugs. Resistance to one drug ranged from 1.4% for ethambutol to 17.7% for rifampicin. The prevalence of MDR-TB ranged from 6.7% for three drugs to 34% for four drugs, with significant predictors being patientsâ age-groups of 25â54 years (p=0.0012) and >55 years (p=0.007). The result showed a high level (58.4%) of MDR-TB from cases in Mpumalanga province. To achieve a higher cure rate in this province, drug-susceptibility tests must be done for every case
Electron correlation energy in confined two-electron systems
Radial, angular and total correlation energies are calculated for four
two-electron systems with atomic numbers Z=0-3 confined within an impenetrable
sphere of radius R. We report accurate results for the non-relativistic,
restricted Hartree-Fock and radial limit energies over a range of confinement
radii from 0.05 - 10 a0. At small R, the correlation energies approach limiting
values that are independent of Z while at intermediate R, systems with Z > 1
exhibit a characteristic maximum in the correlation energy resulting from an
increase in the angular correlation energy which is offset by a decrease in the
radial correlation energy
Paediatric inflammatory multisystem syndrome : what should we look out for in South Africa?
Despite the mayhem caused by COVID-19, children appear largely to have been spared. The disease in children is also more forgiving than in adults, and most children experience mild symptoms or are asymptomatic. While clinical presentation in children is similar to that in adults, with symptoms including fever, cough, sneezing, sore throat and malaise, progression to more severe lower respiratory tract disease is significantly less common. There have been reports of gastrointestinal manifestations in children, including diarrhoea and vomiting.http://www.samj.org.zaam2021ImmunologyPaediatrics and Child Healt
Potential-density pairs for axisymmetric galaxies: the influence of scalar fields
We present a formulation for potential-density pairs to describe axisymmetric
galaxies in the Newtonian limit of scalar-tensor theories of gravity. The
scalar field is described by a modified Helmholtz equation with a source that
is coupled to the standard Poisson equation of Newtonian gravity. The net
gravitational force is given by two contributions: the standard Newtonian
potential plus a term stemming from massive scalar fields. General solutions
have been found for axisymmetric systems and the multipole expansion of the
Yukawa potential is given. In particular, we have computed potential-density
pairs of galactic disks for an exponential profile and their rotation curves.Comment: 8 pages, no figures, corrected version to the one that will appear in
Gen. Relativ. Gravit., where a small typo in eq. (13) is presen
Stripes and holes in a two-dimensional model of spinless fermions and hardcore bosons
We consider a Hubbard-like model of strongly-interacting spinless fermions
and hardcore bosons on a square lattice, such that nearest neighbor occupation
is forbidden. Stripes (lines of holes across the lattice forming antiphase
walls between ordered domains) are a favorable way to dope this system below
half-filling. The problem of a single stripe can be mapped to a spin-1/2 chain,
which allows understanding of its elementary excitations and calculation of the
stripe's effective mass for transverse vibrations. Using Lanczos exact
diagonalization, we investigate the excitation gap and dispersion of a hole on
a stripe, and the interaction of two holes. We also study the interaction of
two, three, and four stripes, finding that they repel, and the interaction
energy decays with stripe separation as if they are hardcore particles moving
in one (transverse) direction. To determine the stability of an array of
stripes against phase separation into particle-rich phase and hole-rich liquid,
we evaluate the liquid's equation of state, finding the stripe-array is not
stable for bosons but is possibly stable for fermions.Comment: 24 pages, 18 figure
Constraints on diffuse neutrino background from primordial black holes
We calculated the energy spectra and the fluxes of electron neutrino emitted
in the process of evaporation of primordial black holes (PBHs) in the early
universe. It was assumed that PBHs are formed by a blue power-law spectrum of
primordial density fluctuations. We obtained the bounds on the spectral index
of density fluctuations assuming validity of the standard picture of
gravitational collapse and using the available data of several experiments with
atmospheric and solar neutrinos. The comparison of our results with the
previous constraints (which had been obtained using diffuse photon background
data) shows that such bounds are quite sensitive to an assumed form of the
initial PBH mass function.Comment: 18 pages,(with 7 figures
Measurement of SUSY masses via cascade decays for SPS 1a
If R-parity conserving supersymmetry exists below the TeV-scale, new particles will be produced and decay in cascades at the LHC. The lightest supersymmetric particle will escape the detectors, thereby complicating the full reconstruction of the decay chains. In this paper we expand on existing methods for determining the masses of the particles in the cascade from endpoints of kinematical distributions. We perform scans in the mSUGRA parameter space to delimit the region where this method is applicable. From the examination of theoretical distributions for a wide selection of mass scenarios it is found that caution must be exerted when equating the theoretical endpoints with the experimentally obtainable ones. We provide analytic formulae for the masses in terms of the endpoints most readily available. Complications due to the composite nature of the endpoint expressions are discussed in relation to the detailed analysis of two points on the SPS 1a line. Finally we demonstrate how a Linear Collider measurement can improve dramatically on the precision of the masses obtained
Cumulative socioeconomic status and incident type 2 diabetes among African American adults from the Jackson heart study
Background: The cumulative socioeconomic status (SES) model posits that childhood and adult experiences accumulate to influence disease risk. While individual SES indicators such as education and income are independently associated with incident type 2 diabetes (T2D), the association of cumulative SES and incident T2D is unclear, especially in African American adults. Methods: We utilized cohort data of African American participants (n = 3681, mean age 52.6 years) enrolled in the Jackson Heart Study from 2000 to 2013 free of T2D or cardiovascular disease at baseline (2000â2004). Cumulative SES scores at baseline were derived using six SES indicators (education, wealth, income, occupation, employment status, and mother's education) categorized as low, middle, and high. Incident T2D was defined at exam 2 (2005â2008) or exam 3 (2009â2013) based on fasting glucose â„126 mg/dL, HbA1c â„ 6.5, reported diabetic medication use, or self-reported physician diagnosis. Proportional hazards regression, allowing for interval censoring, was used to estimate the association between cumulative SES and incident T2D (hazard ratio(HR), 95% confidence interval (CI)) after adjustment for covariates. Sex and age differences were tested using interaction terms. Results: There were 544 incident T2D cases. The association between low (versus high) cumulative SES and incident T2D was not significant (HR 1.04 [95% CI 0.85, 1.28]) and did not differ by sex (p value for interaction>0.05). However, there were differences by (age p value for interaction = 0.0052 for middle-aged adults and 0.0186 for older adults). Low (versus high) cumulative SES was associated a greater hazard of incident T2D among those 20â46 years (HR 1.12 [95% CI 1.03, 1.21]), 47â59 years (HR 1.25 [95% CI 1.06, 1.47]) and those 60â93 years (HR 1.39 [95% CI 1.09, 1.78]) after adjustment for sex and family history of diabetes. Associations attenuated after adding behavioral and lifestyle risk factors. Conclusion: The association of low cumulative SES and incident T2D differed by age, which may suggest interventionist should consider impacts of SES on T2D by age
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