H. de Lubac: el misterio del hombre en el misterio de Dios

This article explains how Henri de Lubac contributed during the 20th century to the renewal of contemporary theology. It also defends the thesis that Lubac played a decisive role in the area of interreligious dialogue

SARS-CoV-2 Vaccines and the Skin

Coronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Skin reactions; VacinesCoronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Reacciones cutáneas; VacunasCoronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Reaccions cutànies; VacunesVaccines against the severe acute respiratory coronavirus 2, which are the first to be used in humans against any coronavirus, were developed and produced in record time. Dermatologic adverse effects appeared during clinical trials and have also been described in the population since approval. Just as descriptions and categorization of skin manifestations of the coronavirus disease 2019 proved important for understanding the disease itself, characterizing the effects of vaccines may also further that goal. This paper reviews the properties of the different types of vaccines currently available and under development and describes how they interact with the immune system and the clinical signs they may cause. We focus on dermatologic adverse effects reported to date and recommendations for managing them

A facility and community-based assessment of scabies in rural Malawi.

Background Scabies is a neglected tropical disease of the skin, causing severe itching, stigmatizing skin lesions and systemic complications. Since 2015, the DerMalawi project provide an integrated skin diseases clinics and Tele-dermatology care in Malawi. Clinic based data suggested a progressive increase in scabies cases observed. To better identify and treat individuals with scabies in the region, we shifted from a clinic-based model to a community based outreach programme. Methodology/Principal findings From May 2015, DerMalawi project provide integrated skin diseases and Tele-dermatological care in the Nkhotakota and Salima health districts in Malawi. Demographic and clinical data of all patients personally attended are recorded. Due to a progressive increase in the number of cases of scabies the project shifted to a community-based outreach programme. For the community outreach activities, we conducted three visits between 2018 to 2019 and undertook screening in schools and villages of Alinafe Hospital catchment area. Treatment was offered for all the cases and school or household contacts. Scabies increased from 2.9% to 39.2% of all cases seen by the DerMalawi project at clinics between 2015 to 2018. During the community-based activities approximately 50% of the population was assessed in each of three visits. The prevalence of scabies was similar in the first two rounds, 15.4% (2392) at the first visit and 17.2% at the second visit. The prevalence of scabies appeared to be lower (2.4%) at the third visit. The prevalence of impetigo appeared unchanged and was 6.7% at the first visit and 5.2% at the final visit. Conclusions/Significance Prevalence of scabies in our setting was very high suggesting that scabies is a major public health problem in parts of Malawi. Further work is required to more accurately assess the burden of disease and develop appropriate public health strategies for its control.post-print876 K

Introducción a la doctrina pneumatológica de San Anselmo de Canterbury

Al cumplirse el XVI Centenario del Concilio I de Constantinopla, cuya aportación fundamental fue la definición de la doctrina católica sobre la divinidad y misión santificadora del Paráclito, el Papa Juan Pablo II recordaba la necesidad, especialmente urgente en estos tiempos, de acudir al Espíritu Santo, de hacerlo más presente en la vida personal, en la Iglesia, y, como lógica consecuencia, en la reflexión teológica: «En esta ocasión se trata no solo de recordar un fórmula de fe que está en vigor en la Iglesia desde hace dieciséis siglos, sino al mismo tiempo hacer cada vez más actual en nuestro espíritu, en la reflexión, en la plegaría, en la contribución de la espiritualidad y de la teología, esa fuerza personal divina que da la vida, ese Don Hipostático —Dominum et vivifícantem—, esa Tercera Persona de la Santísima Trinidad que en esta fe es participada por cada una de las almas y por toda la Iglesia, conduciéndola por caminos de santidad y de amor» '

Tomographic findings and mortality in patients with severe and critical pneumonia with COVID-19 diagnosis

Introduction: A high percentage of patients with non-severe (17.9%) and severe (2.9%) atypical pneumonia do not display pulmonary tomographic findings upon hospital admission; furthermore, lesion associated with COVI-19 are peripherally distributed in a multifocal ground-glass pattern, as well as displaying an irregular consolidation pattern, with a posterior or lower lobe predilection. The main objective of this study was to identify the pulmonary radiological patterns in patients diagnosed with SARS-CoV-2 pneumonia, the factors associated with the need for mechanical ventilation, as well as their survival rates at 30 days. Methods: We report the pulmonary tomographic findings of 490 consecutive patients with severe and critical pneumonia due to SARS-CoV-2. The patients were classified according to the tomography and demographic findings, sepsis severity prognostic scales, Charlson comorbidity index (CCI), the Sequential Organ Failure Assessment (SOFA), and the Acute Physiology and Chronic Health Evaluation (APACHE IV). The Kaplan-Meier method was used to calculate survival distributions. Results: 89.80% of patients had ground-glass opacities, 81.63% radiologic consolidation sign, 42.45% vascular thickening pattern, 37.55% lymphadenopathies, 14.90% pleural effusion, and 2.65% pulmonary thrombosis; meanwhile, 91.02% had bilateral lesions, 85.51% had peripheral lesions, and 75.92% had basal lobe lesions. APACHE IV (HR, 1.191, 95% CI [1.126, 1.260]), SOFA (HR, 5.178, 95%CI [3.103, 8.641]), and CCI (HR, 0.673, 95%CI [0.510, 0.889]), as well as the pulmonary damage severity index (HR, 1.282, 95%CI [1.151, 1.428]), predict the need for invasive mechanical ventilation. Only moderate ARDS patients with mild and severe lung disease showed different 30-day mortality distributions (χ2 = 7.00, p = 0.008). Discussion: Although the survival distributions did not vary significantly, an overwhelming majority of patients (i.e., 84.35%) with a higher pulmonary damage severity index (i.e., 23>) died within 30 days of hospital admission, while only 25.91% with moderate lung damage and 2.42% with mild lung damage

Prominent Cutaneous Manifestation of COVID-19: A Case Report

The new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen and the subsequent coronavirus disease (COVID-19) mainly affect the lung.1 Respiratory symptoms are key for diagnosis, however, increasing knowledge has led to the understanding that COVID-19 induces multiorgan pathology. The first descriptions of clinical symptoms reported that 0.2% of patients admitted to hospitals in China presented with a skin rash.1 Following this, in Italy 20.4% of 88 admitted patients treated by dermatologists presented with symptoms of the skin.2 In April 2020, the first comprehensive classification of skin manifestations in patients within the full spectrum of COVID-19 severity, from intensive care, hospital wards, and home care, as well as those without symptoms, was published.3 The study analysed 375 patients with PCR-confirmed diagnosis or with suspected diagnosis, meeting the European Centre for Disease Prevention and Control (ECDC) clinical criteria. Although following certain patterns, skin manifestations showed extreme variability. Five skin patterns were defined: pseudo-chilblain, vesicular, urticarial, maculopapular, and livedo/necrosis. Each pattern usually associated with a different age category, evolutionary moment of the process, and systemic severity.3 The majority of these manifestations were non-specific and their cause–effect relationship with the virus is not fully established. The limited access to confirmatory tests and concurrence of different drugs to treat the disease make it difficult to reach any conclusions. The authors present the case of a patient in whom the most striking COVID-19 manifestation was dermatological

Scanning Electrochemical Microscopy characterization of sol-gel coatings applied on AA2024-T3 substrate

Scanning electrochemical microscopy was employed to characterize the local surface activity of an AA2024-T3 coated with sol-gel. Corrosion inhibitors were added to the sol-gel either as soluble chemical species, namely 1,2,3-benzotriazole, Na-(diethyl(dithiocarbamate)), and piperazine, or using Ce(III)-montmorillonite containers. The Scanning electrochemical microscopy was operated in the feedback mode by using ferrocene-methanol as redox mediator. This experimental procedure allowed evaluation of the coating behaviour in damaged and non-damaged areas from the analysis of Z-approach curves and 2D maps. The results evidence differences in the local electrochemical activity of the modified coatings that correlate well with averaging electrochemical measurements using electrochemical impedance spectroscop

EL SOLAR MAYA-CH’OL Y SUS SABERES ETNOBOTÁNICOS EN COMUNIDADES AL NORTE DE CHIAPAS, MÉXICO

El agroecosistema denominado solar presenta un papel fundamental en el sistema de vida del pueblo ch’ol en el sureste de México; la conservación del conocimiento tradicional de especies vegetales, ha permitido obtener diversos recursos para la subsistencia y han contribuido en los ingresos económicos de las familias. Por ello, los objetivos de esta investigación fueron describir el agroecosistema denominado “solar”, identificar las especies vegetales que las familias choles utilizan y determinar las categorías antropocéntricas del uso de estas especies, con base a sus conocimientos tradicionales. Esta investigación se realizó en comunidades maya-ch’ol del Valle de Tulijá, al norte de Chiapas, México; para la obtención de la información, se implementó el proceso metodológico SIV (Sistemas de Vida), se aplicaron herramientas participativas y técnicas tradicionales de muestreo etnobotánico, en el periodo agosto 2016 a agosto 2017; el análisis de la información fue desarrollado mediante métodos descriptivos. El solar maya-ch’ol se caracteriza por presentar cuatro espacios zonificados destinados para el aprovechamiento de sus recursos, los cuales son traspatio, hortaliza, jardín y reserva forestal; en los cuales se registran 131 especies útiles, agrupadas en 58 familias, sobre todo representadas por Fabaceae (11 especies), Malvaceae y Rutaceae (8 especies); de todas las especies destaca el registro de 65 nombres de plantas en lengua ch’ol. Del total de especies, se presenta una clasificación de 19 categorías de usos antropocéntricos, representados en su mayoría por uso comestible, medicinal y ornamental; asimismo, los biotipos usados con mayor frecuencia son los árboles, y las partes más utilizadas son los frutos y las hojas. Bajo tal contexto, este estudio permitió revalorizar los saberes etnobotánicos en relación al manejo de los componentes del solar; además, se hace evidente la importancia de este espacio en el ámbito del sistema de vida del pueblo maya-ch’ol