Measurement of the forward-backward asymmetry in Λ0b and Λ¯0b baryon production in pp¯ collisions at s√=1.96 TeV

We measure the forward-backward asymmetry in the production of Λ0b and Λ¯0b baryons as a function of rapidity in pp¯ collisions at s√=1.96  TeV using 10.4  fb−1 of data collected with the D0 detector at the Fermilab Tevatron collider. The asymmetry is determined by the preference of Λ0b or Λ¯0b particles to be produced in the direction of the beam protons or antiprotons, respectively. The measured asymmetry integrated over rapidity y in the range 0.1<|y|<2.0 is A=0.04±0.07(stat)±0.02(syst)

Oncogenic Signaling Pathways in The Cancer Genome Atlas

Genetic alterations in signaling pathways that control cell-cycle progression, apoptosis, and cell growth are common hallmarks of cancer, but the extent, mechanisms, and co-occurrence of alterations in these pathways differ between individual tumors and tumor types. Using mutations, copy-number changes, mRNA expression, gene fusions and DNA methylation in 9,125 tumors profiled by The Cancer Genome Atlas (TCGA), we analyzed the mechanisms and patterns of somatic alterations in ten canonical pathways: cell cycle, Hippo, Myc, Notch, Nrf2, PI-3-Kinase/Akt, RTK-RAS, TGFb signaling, p53 and beta-catenin/Wnt. We charted the detailed landscape of pathway alterations in 33 cancer types, stratified into 64 subtypes, and identified patterns of co-occurrence and mutual exclusivity. Eighty-nine percent of tumors had at least one driver alteration in these one alteration potentially targetable by currently available drugs. Thirty percent of tumors had multiple targetable alterations, indicating opportunities for combination therapy

Comparison of ether lipids found in archaeonbacterial thermophiles Pyrococcus furiousus, Methanopyrus kandleri, and methanothermus fervidus

Peer reviewed: YesNRC publication: Ye

Enhanced stability of archaeosomes against attack by pancreatic lipase and bile salts

Peer reviewed: YesNRC publication: Ye

In vitro assessment of archaeosome stability for oral delivery of vaccines

Peer reviewed: YesNRC publication: Ye

Evidence for s-channel single top quark production in pp¯ collisions at s=1.96 TeV

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Measurement of spin correlation between top and antitop quarks produced in p¯p collisions at √ s = 1.96 TeV

We present a measurement of the correlation between the spins of t and View the MathML source quarks produced in proton–antiproton collisions at the Tevatron Collider at a center-of-mass energy of 1.96 TeV. We apply a matrix element technique to dilepton and single-lepton+jets final states in data accumulated with the D0 detector that correspond to an integrated luminosity of 9.7 fb−1. The measured value of the correlation coefficient in the off-diagonal basis, View the MathML source, is in agreement with the standard model prediction, and represents evidence for a top–antitop quark spin correlation difference from zero at a level of 4.2 standard deviations