Crowded space: a review on radar measurements for space debris monitoring and tracking

Space debris monitoring is nowadays a priority for worldwide space agencies, due to the serious threat that these objects present. More and more efforts have been made to extend the network of available radar systems devoted to the control of space. A meticulous review has been done in this paper, in order to find and classify the considerable amounts of data provided by the scientific community that deal with RADAR measurement for the debris monitoring and tracking. The information gathered is organized based on the volume of found data and classified taking into account the geographical location of the facilities

An in-line coaxial-to-waveguide transition for q-band single-feed-per-beam antenna systems

An in-line transition between a coaxial cable and rectangular waveguide operating in Q-band (33–50 GHz) is presented. The aim of the work is to minimize the modifications in the waveguide to the strictly necessary to overcome the manufacturing issues due to the high frequencies involved. In addition, the transition is compact and it does not increase the space occupation on the transverse section, this suggests its application in horn antennas clusters arrangement. The operating principle consists of both a modal conversion and an impedance matching between the devices. The modal conversion is realized in an intermediate region, where the coaxial penetrates in the waveguide: the device geometry is designed so that the electric field in the transition is a trade-off between the TEM mode of the coaxial and the TE10 of the guide. A shaped waveguide backshort and a reactive air gap in the coaxial cable co-participate to achieve the matching. An optimized Chebyshev stepped transformer completes the transition to fulfil the impedance mismatch with the full waveguide. The design issues and technological aspects are considered. The influences of the feeding pin misalignment, the presence of groove is included in the analysis and these practical aspects are discussed and numerically validated via the scattering parameters analysis of the proposed design. The return loss is higher than 25 dB over the whole Q-band

Migraine and gastrointestinal disorders in middle and old age: A UK Biobank study

Introduction: Migraine is a prevalent condition causing a substantial level of disability worldwide. Despite this, the pathophysiological mechanisms are not fully understood. Migraine often co-occurs with gastrointestinal disorders, but the direction of a potential causal link is unclear. The aim of this project was to investigate the associations between migraine and several gastrointestinal disorders in the same cohort in order to determine the relative strengths of these associations. Methods: This cross-sectional study examined whether migraine is associated with irritable bowel syndrome (IBS), peptic ulcers, Helicobacter pylori (HP) infections, celiac disease, Crohn's disease and ulcerative colitis. Baseline data covering 489,753 UK Biobank participants (migraine group: n = 14,180) were analyzed using Pearson's chi-square tests and adjusted binary logistic regression models. Results: Migraine was significantly associated with IBS (odds ratio [OR] 2.24, 95% confidence interval [CI] 2.08–2.40, p <.001) and peptic ulcers (OR 1.55, 95% CI 1.35–1.77, p <.001). Migraine was not associated with HP infection (OR 1.34, 95% CI 1.04–1.73, p =.024), celiac disease (OR 1.29, 95% CI 1.04–1.60, p =.023), Crohn's disease (OR 1.08, 95% CI 0.80–1.45, p =.617) or ulcerative colitis (OR 1.00, 95% CI 0.79–1.27, p =.979) after adjusting for multiple testing. Conclusions: Migraine was associated with IBS and peptic ulcers in this large population-based cohort. The associations with HP infection, celiac disease, Crohn's disease, and ulcerative colitis did not reach significance, suggesting a weaker link between migraine and autoimmune gastrointestinal conditions or HP infection

A multiband proximity-coupled-fed flexible microstrip antenna for wireless systems

A multiband printed microstrip antenna for wireless communications is presented. The antenna is fed by a proximity-coupled microstrip line, and it is printed on a flexible substrate. The antenna has been designed using a general-purpose 3D computeraided design software (CAD), CST Microwave Studio, and then realized. The comparison between simulated and measured results shows that the proposed antenna can be used for wireless communications for WLAN systems, covering both the WLAN S-band (2.45GHz) and C-band (5.2GHz), and the Wi-Max 3.5GHz band, with satisfactory input matching and broadside radiation pattern. Moreover, it has a compact size, is very easy to realize, and presents a discrete out-of-band rejection, without requiring the use of stop-band filters. The proposed structure can be used also as a conformal antenna, and its frequency response and radiated field are satisfactory for curvatures up to 65°

A New Monitor and Control Power Supply PCB for Biasing LNAs of Large Radio Telescopes Receivers

The biasing of low noise amplifiers (LNA) is of paramount importance for the receivers of large radio telescopes. High stability, optimal trade-off between gain and noise figure, remote control, and mitigation of the radio frequency interferences (RFIs) are all desirable features in the choice of the electronic board devoted to power supply the LNAs. In this paper, we propose the design and characterization of a multilayer printed circuit board (PCB), named GAIA, able to meet all the aforementioned requirements. The GAIA board is a 3-Unit, four-layer, rack-mountable, programmable PCB for the remote biasing of the LNAs, with monitor and control capabilities, specifically designed to operate in the receivers of the 64-m diameter Sardinia Radio Telescope (SRT). We describe the architecture, layout, and measurements of the GAIA board. Our results show that the GAIA power supply provides high stability of the output bias voltages and, in comparison with the old analogic biasing board used so far in the SRT receivers, it shows comparable or better frequency stability, other than a remarkable mitigation of the RFIs

Space Debris Detection in Low Earth Orbit with the Sardinia Radio Telescope

Space debris are orbiting objects that represent a major threat for space operations. The most used countermeasure to face this threat is, by far, collision avoidance, namely the set of maneuvers that allow to avoid a collision with the space debris. Since collision avoidance is tightly related to the knowledge of the debris state (position and speed), the observation of the orbital debris is the key of the problem. In this work a bistatic radar configuration named BIRALET (BIstatic RAdar for LEO Tracking) is used to detect a set of space debris at 410 MHz, using the Sardinia Radio Telescope as the receiver antenna. The signal-to-noise ratio, the Doppler shift and the frequency spectrum for each debris are reported

Unravelling the functional and technological potential of soy milk based microencapsulated Lactobacillus crispatus and Lactobacillus gasseri

The main aim of this study was to evaluate the potential of microencapsulation with soy milk as a carrier, conducted by spray-drying, on three mixed cultures of functional vaginal lactobacilli, Lactobacillus crispatus (BC1, BC3, and BC4) and Lactobacillus gasseri BC9, that could be further exploited as an adjunct in health foods. The i) physicochemical properties (using scanning electronic microscopy), ii) viability of encapsulated bacteria over time, and iii) functional features of powders containing the encapsulated bacteria were characterised considering different storage conditions. All microbial mixtures exhibited high viability for 90 d of storage, regardless of the storage conditions. All microencapsulated microbial combinations, excluding L. crispatus BC3 + L. gasseri BC9, exhibited hydrophobicity values exceeding 60%. Moreover, regardless of the considered combination, the in vitro digestion results exhibited a more significant decrease in cell viability for non-encapsulated microbial combinations than that of the encapsulated strains

Dissecting the genetic overlap between severe mental disorders and markers of cellular aging: Identification of pleiotropic genes and druggable targets

Patients with severe mental disorders such as bipolar disorder (BD), schizophrenia (SCZ) and major depressive disorder (MDD) show a substantial reduction in life expectancy, increased incidence of comorbid medical conditions commonly observed with advanced age and alterations of aging hallmarks. While severe mental disorders are heritable, the extent to which genetic predisposition might contribute to accelerated cellular aging is not known. We used bivariate causal mixture models to quantify the trait-specific and shared architecture of mental disorders and 2 aging hallmarks (leukocyte telomere length [LTL] and mitochondrial DNA copy number), and the conjunctional false discovery rate method to detect shared genetic loci. We integrated gene expression data from brain regions from GTEx and used different tools to functionally annotate identified loci and investigate their druggability. Aging hallmarks showed low polygenicity compared with severe mental disorders. We observed a significant negative global genetic correlation between MDD and LTL (rg = −0.14, p = 6.5E−10), and no significant results for other severe mental disorders or for mtDNA-cn. However, conditional QQ plots and bivariate causal mixture models pointed to significant pleiotropy among all severe mental disorders and aging hallmarks. We identified genetic variants significantly shared between LTL and BD (n = 17), SCZ (n = 55) or MDD (n = 19), or mtDNA-cn and BD (n = 4), SCZ (n = 12) or MDD (n = 1), with mixed direction of effects. The exonic rs7909129 variant in the SORCS3 gene, encoding a member of the retromer complex involved in protein trafficking and intracellular/intercellular signaling, was associated with shorter LTL and increased predisposition to all severe mental disorders. Genetic variants underlying risk of SCZ or MDD and shorter LTL modulate expression of several druggable genes in different brain regions. Genistein, a phytoestrogen with anti-inflammatory and antioxidant effects, was an upstream regulator of 2 genes modulated by variants associated with risk of MDD and shorter LTL. While our results suggest that shared heritability might play a limited role in contributing to accelerated cellular aging in severe mental disorders, we identified shared genetic determinants and prioritized different druggable targets and compounds