Occupational lung cancer among fisherman: a triple case report

Background: The World Health Organisation places lung cancer as the leading cause of cancer mortality in the world. The fishermen are one of the most important consumers of tobacco, which remains the main risk factor for lung cancer. However, there are no epidemiological data on the role of other causes, particularly occupational ones, in genesis of this disease. The objective of our work is to expose medical and occupational data of 3 fishermen with lung cancer and discuss a possible occupational origin of their pathology. Case presentation: This is a case report where we describe medical and occupational data of 3 fishermen working in the port of Tangier (Morocco) who have lung cancer. The first one is an ordinary fisherman, the second is a mechanic on board and the third is an ordinary fisherman but who worked 21 years ago aboard deep-sea fishing ships as a helper in the mechanic room. All fishermen were in the fifties; the third one never smoked while the other two were described as heavy smokers. All of them were exposed during their daily work to some chemicals liable to cause lung cancer. The anatomopathological types found were 2 cases of adenocarcinoma which is the histopathological variant often found in cases of occupational origin and one case of squamous cell carcinoma. Conclusions: The results obtained after studying these 3 cases suggest the possibility of occupational origin in the genesis of lung cancer among fishermen; however, the increased smoking rate in this population remains the most probable factor and helps the preventive approach to be adopted. More detailed epidemiological studies would highlight the possible role of occupational causes in the carcinogenesis of this pathology.

Optimal design of sensors via geometric criteria

We consider a convex set Ω and look for the optimal convex sensor ω⊂ Ω of a given measure that minimizes the maximal distance to the points of Ω. This problem can be written as follows inf{dH(ω,Ω)||ω|=candω⊂Ω}, where c∈ (0 , | Ω |) , dH being the Hausdorff distance. We show that the parametrization via the support functions allows us to formulate the geometric optimal shape design problem as an analytic one. By proving a judicious equivalence result, the shape optimization problem is approximated by a simpler minimization problem of a quadratic function under linear constraints. We then present some numerical results and qualitative properties of the optimal sensors and exhibit an unexpected symmetry breaking phenomenonI. Ftouhi is supported by the Alexander von Humboldt Foundation and has been partially supported by the project ANR-18-CE40-0013 SHAPO financed by the French Agence Nationale de la Recherche (ANR). E. Zuazua has been funded by the Alexander von Humboldt-Professorship program, the ModConFlex Marie Curie Action, HORIZON-MSCA-2021-DN-01, the COST Action MAT-DYN-NET, the Transregio 154 Project “Mathematical Modelling, Simulation and Optimization Using the Example of Gas Networks” of the DFG, grants PID2020-112617GB-C22 and TED2021-131390B-I00 of MINECO (Spain), and by the Madrid Government-UAM Agreement for the Excellence of the University Research Stay in the context of the V PRICIT (Regional Programme of Research and Technological Innovation

Proposal Decision Support Process for Urban Goods Delivery

This paper proposes a collaborative process to handle demands received by a carrier for urban goods delivery.The purpose of this article is to provide support for carriers analyzing the demands,physical resources,human resources,risks and profitability,in order to decide processing internally or externally a goods delivery demand or rejecting it.Such a process,called CUFP(Collaborative Urban Freight Process),is based on an analysis of urban movements of goods,divided into four stages:Check out of extreme conditions,feasibility study,exploitation study and execution

Sleep apnea syndrome: experience of the pulmonology department in Ibn Sina Hospital, Rabat, Morocco

Introduction Sleep apnea syndrome is a highly prevalent disorder that is still underdiagnosed and undertreated and whose obstructive form is the most common. The diagnosis is suspected on clinical signs collected by interrogation and questionnaires (Berlin questionnaire and Epworth sleepiness scale), then confirmed by objective sleep study findings (polygraphy or polysomnography). It is necessary to conduct studies in each context on the characteristics and management of sleep apnea syndrome comprising the testing of reliability of the questionnaires. Methods Prospective and descriptive study of 104 patients addressed to sleep consultation at pulmononology Department of Ibn Sina Hospital, Morocco over a period of 5 years (January 2006 to December 2010), agreed to participate in the study, responded to a predetermined questionnaire, and benefited from clinical examination and paraclinical tests including a polygraphy or a polysomnography Results 59(56.7%) patients had an obstructive sleep apnea-hypopnea syndrome with a similar prevalence in both sexes. 32.2% of patients were obese and 28,8% had cardio-vascular diseases. Snoring, excessive daytime sleepiness and witnessed apnea were found in respectively 79.7%, 50.8% and 16.9%. Berlin questionnaire and Epworth sleepiness scale had an acceptable internal consistency against apnea hypopnea index with a Cronbach’s alpha coefficient respectively 0.79 and 0.78. Depending on severity, clinical impact and results of investigations, the adequate treatment has been proposed based on the 2010 recommendations for clinical practice. Conclusion This study has provided an idea about the profile and the management of patients having an obstructive sleep apnea-hypopnea syndrome and showed that both Berlin questionnaire and Epworth sleepiness scale are two simple and reliable methods in our context. A larger and further study across the country should be considered.Pan African Medical Journal 2012; 13:2

Overlap syndrome: Association of chronic obstructive pulmonary disease and obstructive sleep apnea syndrome

AbstractCOPD and the OSAHS are both common diseases affecting respectively 10% and 5% of the adult population over 40years of age. Their coexistence, which is denominated as «overlap syndrome», can occur in about 0.5% of this population.Aim and materialsTo assess the existence of a prevalence of OSAHS in patients with COPD through a prospective analysis: 70 had a confirmed isolated OSAHS (group A) and 11 had an OS (group B), all were compiled from January 2007 to June 2012.ResultsThe prevalence of OS in our study was 13.6%, OS patients were older than the isolated OSAHS patients (p<0.05) with a male predominance in the Overlap arm (p<0.05), and BMI was similar between the 2 groups (p=0.22). Tobacco is retained as a risk factor and 81.8% of patients with Overlap were smoking (p<0.05). Clinical signs most reported are nocturnal snoring and daytime sleepiness. The Epworth Sleepiness Scale was higher than 10 in the 2 groups (p<0.05). The Berlin questionnaire realized in 30 subjects in group A, was positive (40% of cases) and was positive in 63.6% of 7 subjects in group B. Spirometry showed that vital capacity, FEV1 and FEV1/CV were significantly decreased in the Overlap group (p<0.001). The recording shows a sleep apnea–hypopnea index (AHI) similar in the two groups (p<0.05).ConclusionThere was no correlation between COPD and OSAHS. The latter is a risk factor for the first

EFFECT OF SALINE WATER IRRIGATION AND FOLIAR SPRAYING OF SALICYLIC ACID ON GROWTH, FLOWERING AND CHEMICAL COMPOSITION OF POT MARIGOLD (Calendula officinalis L.) PLANT

This study was carried out to investigate the effect of saline water irrigation at 2000, 4000, 6000, 8000 and 10000 ppm by using a mixture of two salts (sodium chloride: calcium chloride, 2:1, w/w)  in addition to tap water  as control and foliar sprayings of Salicylic acid (SA) at 100, 200 and 300 ppm in addition to tap water as control on growth, flowering and chemical composition of pot marigold plants in the two successive seasons of 2014/2015 and 2015/2016 in the Faculty of Agriculture, Ain Shams University, Qalyubia Governorate, Egypt. Results revealed that all tested foliar applications of SA increased all vegetative growth characteristics (plant height, number of leaves /plant, leaf area, number of branches/plant, diameter of stem, fresh and dry weights of vegetative growth and roots, and roots volume), and flowering attributes (number of inflorescences/plant, diameter of inflorescence, fresh and dry weights of inflorescences). While, saline water irrigation decreased growth, flowering parameters, chlorophyll, carotene contents in flowers and some minerals contents of the vegetative growth, i.e. nitrogen, phosphorus and potassium percentages. However, saline water irrigation increased proline and some mineral contents, i.e. calcium, sodium and chloride percentages of the vegetative growth. In most cases, under the same saline water irrigation conditions spraying SA at 100 and 200 ppm concentrations alleviated the salinity effect on the plants, enhanced the plant growth and increased the flowering parameters. The most effective treatments which enhance growth, flowering parameters, chlorophyll content, carotene contents in flowers, proline and mineral contents were found to be 100 and 200 ppm SA spraying under nonsaline conditions

LES ADENOPATHIES MEDIASTINALES : ETUDE RETROSPECTIVE A PROPOS DE 64 CAS

Introduction: They are an important chapter in the pathology of the mediastinum because of the number of relay nodes, and because of the frequency and the diagnosis difficulties they pose. Materials and Methods: Through a retrospective study of 64 cases of mediastinal lymphadenopathies collected during two years. We analyzed the various tools diagnosis commonly applied and the different etiologies identified. Results: Analysis of the results of assessments allowed the etiological diagnosis in 50 cases (78.12%): 32 cases of metastasis of lung cancer, 7 cases of lymphoma, 6 cases of sarcoidosis, 3 cases of lymph node tuberculosis and 2 cases of multifocal tuberculosis. Through this study we will try to develop the means of positive and etiological diagnosis used in our department and the most frequent etiologies found.Introduction : Elles constituent un chapitre important de la pathologie du médiastin en raison du nombre de relais lymphatiques et en raison de la fréquence et des difficultés diagnostiques qu’elles posent. Matériels et méthodes: A travers une étude rétrospective portant sur 64 cas d’adénopathies médiastinales colligées durant 2 ans. Nous avons analysé les différents moyens de diagnostic couramment pratiqués ainsi que les différentes étiologies recensées. Résultats : L’analyse des résultats des bilans a permis de poser le diagnostic étiologique dans 50 cas, soit dans 78,12 % : 32 cas de métastases d’un cancer bronchique, 7 cas de lymphomes, 6 cas de sarcoïdose, 3 cas de tuberculose ganglionnaire et 2 cas de tuberculose multifocale. A travers cette étude nous allons essayer de mettre au point sur les moyens de diagnostic positif et étiologique utilisés ainsi que les étiologies les plus fréquemment retrouvées

Métastases pleuropulmonaires révélant un mélanome malin de la conjonctive chez un sujet jeune

Le mélanome de la conjonctive est une tumeur rare avec une incidence de 0,03 à 0,08 pour 100000 dans la population blanche. Le mélanome malin métastatique constitue environ 5% de toutes les tumeurs malignes secondaires du poumon. Nous rapportons un cas de métastase pleurale et pulmonaire d'un mélanome conjonctival de découverte fortuite chez un sujet jeune.Pan African Medical Journal 2016; 2