Steps Toward the Creation of a Carbon Nanotube Single Electron Transistor

This report details work toward the fabrication of a single-electron transistor created from a single-walled carbon nanotube (SWNT). Specifically discussed is a method for growing carbon nanotubes (CNTs) via carbon vapor deposition (CVD). The growth is catalyzed by a solution of 0.02g Fe(NO3)3·9H2O, 0.005g MoO2(acac)2, and 0.015g of alumina particles in 15mL methanol. SWNT diameter ranges from 0.6 to 3.0 nm. Also discussed is a method to control nanotube growth location by patterning samples with small islands of catalyst. A novel “maskless” photolithographic process is used to focus light from a lightweight commercial digital projector through a microscope. Catalyst islands created by this method are approximately 400 μm2 in area

A Scenario-based Parametric Analysis of the Army Personnel-to-assignment Matching Problem

This study aims to compare linear programming and stable marriage approaches to the personnel assignment problem under conditions of uncertainty. Robust solutions should exhibit reduced variability of solutions in the presence of one or more additional constraints or problem perturbations added to some baseline problems.Several variations of each approach are compared with respect to solution speed, solution quality as measured by officer-to-assignment preferences and solution robustness as measured by the number of assignment changes required after inducing a set of representative perturbations or constraints to an assignment instance. These side constraints represent the realistic assignment categorical priorities and limitations encountered by army assignment managers who solve this problem semiannually, and thus the synthetic instances considered herein emulate typical problem instances

Cell Type Impacts Accessibility of mRNA to Silencing by RNA Interference

RNA interference (RNAi) is a potent mechanism that silences mRNA and protein expression in all cells and tissue types. RNAi is known to exert many of its functional effects in the cytoplasm, and thus, the cellular localization of target mRNA may impact observed potency. Here, we demonstrate that cell identity has a profound impact on accessibility of apolipoprotein E (ApoE) mRNA to RNAi. We show that, whereas both neuronal and glial cell lines express detectable ApoE mRNA, in neuronal cells, ApoE mRNA is not targetable by RNAi. Screening of a panel of thirty-five chemically modified small interfering RNAs (siRNAs) did not produce a single hit in a neuronal cell line, whereas up to fifteen compounds showed strong efficacy in glial cells. Further investigation of the cellular localization of ApoE mRNA demonstrates that ApoE mRNA is partially spliced and preferentially localized to the nucleus ( approximately 80%) in neuronal cells, whereas more than 90% of ApoE mRNA is cytoplasmic in glial cells. Such an inconsistency in intracellular localization and splicing might provide an explanation for functional differences in RNAi compounds. Thus, cellular origin might have an impact on accessibility of mRNA to RNAi and should be taken into account during the screening process

Dissociation of structural and functional integrities of the motor system in amyotrophic lateral sclerosis and behavioral-variant frontotemporal dementia

Background and Purpose: This study investigated the structural and functional changes in the motor system in amyotrophic lateral sclerosis (ALS; n=25) and behavioral-variant fronto-temporal dementia (bvFTD; n=17) relative to healthy controls (n=37). Methods: Structural changes were examined using a region-of-interest approach, applying voxel-based morphometry for gray-matter changes and diffusion tensor imaging for white-matter changes. Functional changes in the motor system were elucidated using threshold-tracking transcranial magnetic stimulation (TMS) measurements of upper motor-neuron excitability. Results: The structural analyses showed that in ALS there were more white-matter changes in the corticospinal and motor-cortex regions and more gray-matter changes in the cerebellum in comparison to controls. bvFTD showed substantial gray- and white-matter changes across virtually all motor-system regions compared to controls, although the brainstem was affected less than the other regions. Direct comparisons across patient groups showed that the gray- and white-matter motor-system changes inclusive of the motor cortex were greater in bvFTD than in ALS. By contrast, the functional integrity of the motor system was more adversely affected in ALS than in bvFTD, with both patient groups showing increased excitability of upper motor neurons compared to controls. Conclusions: Cross-correlation of structural and functional data further revealed a neural dissociation of different motor-system regions and tracts covarying with the TMS excitability across both patient groups. The structural and functional motor-system integrities appear to be dissociated between ALS and bvFTD, which represents useful information for the diagnosis of motor-system changes in these two disorders

Dynamical locality of the nonminimally coupled scalar field and enlarged algebra of Wick polynomials

We discuss dynamical locality in two locally covariant quantum field theories, the nonminimally coupled scalar field and the enlarged algebra of Wick polynomials. We calculate the relative Cauchy evolution of the enlarged algebra, before demonstrating that dynamical locality holds in the nonminimally coupled scalar field theory. We also establish dynamical locality in the enlarged algebra for the minimally coupled massive case and the conformally coupled massive case.Comment: 39p

Comparison of an ultra-low volume (ULV) sprayer against a conventional sprayer, for foliar fertiliser and fungicide applications in turfgrass

Two field studies (I and II) at the University of Nebraska-Lincoln: John Seaton Anderson Turfgrass Research Facility near Mead, NE, USA, were conducted to determine if a new ultra-low volume (ULV) sprayer can apply foliar nutrient, growth regulator, and fungicide treatments, in a manner similar to that of a conventional sprayer. Treatments were applied over creeping bentgrass ‘L-93’ (Agrostis stolonifera L.) managed as a fairway at 561 l · ha−1 and 47 l · ha−1 with the conventional and ULV sprayer, respectfully. Data were collected for chlorophyll content with a chlorophyll meter, and for the normalised difference vegetation index (NDVI) with a turf colour meter. Each plot was harvested for biomass at 21 days after treatment. Study II compared the ULV sprayer and a conventional sprayer, for the control of brown patch (Rhizoctonia solani Kuhn) in creeping bentgrass. The treatments were propiconazole and azoxystrobin. Spray volume was 561 l · ha−1 for the conventional sprayer, and 19 l · ha−1 for the ULV sprayer. Statistical differences in turf quality or dry weight reductions between the conventional and ULV sprayer were not detected. Brown patch control was also similar between the two sprayers, but azoxystrobin provided better control than propiconazole. Even with a 30-fold decrease in application volume, the results indicated that the Kamterter ULV sprayer may be a useful and effective management option for foliar fertiliser and fungicide applications in turfgrass

SMARTER Teamwork: System for Management, Assessment, Research, Training, Education, and Remediation for Teamwork

The rapid adoption of Team-Maker and the Comprehensive Assessment of Team Member Effectiveness (CATME), tools for team formation and peer evaluation, make it possible to extend their success to have a significant impact on the development of team skills in higher education. The web-based systems are used by over 700 faculty at over 200 institutions internationally. This paper and its accompanying poster will describe strategies for broadening the scope of those tools into a complete system for the management of teamwork in undergraduate education. The System for the Management, Assessment, Research, Training, Education, and Remediation of Teamwork (SMARTER Teamwork) has three specific goals: 1) to equip students to work in teams by providing them with training and feedback, 2) to equip faculty to manage student teams by providing them with information and tools to facilitate best practices, and 3) to equip researchers to understand teams by broadening the system’s capabilities to collect additional types of data so that a wider range of research questions can be studied through a secure researcher interface. The three goals of the project support each other in hierarchical fashion: research informs faculty practice, faculty determine the students’ experience, which, if well managed based on research findings, equips students to work in teams. Our strategies for achieving these goals are based on a well-accepted training model that has five elements: information, demonstration, practice, feedback, and remediation. Different outcomes are expected for each group of people. For the students, both individual outcomes, such as student learning, and team outcomes, such as the development of shared mental models, are expected. For the faculty, individual outcomes such as faculty learning and faculty satisfaction are expected. The outcomes for researchers will be community outcomes, that is, benefits for stakeholders outside the research team, such as generating new knowledge for teaming theory and disseminating best practices. Measuring these outcomes is the basis for the project’s evaluation plan

Optimising the Efficiency of a Quantum Memory based on Rephased Amplified Spontaneous Emission

We studied the recall efficiency as a function of optical depth of rephased amplified spontaneous emission (RASE), a protocol for generating entangled light. The experiments were performed on the $^{3}\! H_{4}$ $\rightarrow$ $^{1}\! D_{2}$ transition in the rare-earth doped crystal Pr$^{3+}$:Y$_{2}$SiO$_{5}$, using a four-level echo sequence between four hyperfine levels to rephase the emission. Rephased emission was observed for optical depths in the range of $\alpha L$ = 0.8 to 2.0 with a maximum rephasing efficiency of 14 % observed while incorporating spin storage. This efficiency is a significant improvement over the previously reported non-classical result but is well short of the predicted efficiency. We discuss the possible mechanisms limiting the protocol's performance, and suggest ways to overcome these limits.Comment: 5 pages, 5 figure