19 research outputs found
Talento humano: el factor clave del servicio
- Publication venue
- 'Facultad de Ciencias Economicas y Administrativas de la Universidad de Cuenca'
- Publication date
- 01/01/2013
- Field of study
Esta investigación se centra en el reconocimiento del Talento Humano como el factor más importante para el servicio de una organización incluyendo el análisis del servicio y cultura organizacional en el siglo XXI.
Se ilustran algunos mecanismos o programas sobre la gestión que una organización debe desarrollar para obtener un Talento Humano calificado y competente en temas de servicio y concluyentes como la transformación de una cultura organizacional centrada en valores, normas y principios, complementados con herramientas efectivas de comunicación y consecución de líderes modernos e innovadores en temas de servicio.
El Talento Humano resalta la prioridad que tienen las organizaciones que están volcadas al cliente que cada día adquieren vigencia y relevancia para lograr ser competitivas en donde se mueven. Por otro lado, el Talento Humano se convierte en la cara de la empresa siendo los máximos vendedores de sus bienes y servicios, para lo cual se debe crear una cultura organizacional con tiempo, constancia y perseverancia.
La metodología utilizada fue de investigación deductiva incluyendo charlas con personas expertas en el tema de servicio, así como la experiencia propia en empresas de servicios y de industria y comercio.
De esta manera se logró establecer una serie de principios y normas de conducta que debe tener el Talento Humano para que una organización sea reconocida como una empresa con una fuerte cultura de servicio.This research focuses on the recognition of human talent as the most important factor for the service of an organization including service analysis and organizational culture in the twenty-first century.
It illustrates some mechanisms or management programs that an organization must develop to get a qualified and competent human talent in services areas and conclusive as the transformation of an organizational culture focused on values, norms and principles, complemented with effective communication tools and achievement of modern and innovative leaders in the areas of service.
The Human Talent highlights the priority as organizations that are geared towards the customer which are now gaining currency and relevance in order to become competitive. On the other hand, the human talent becomes the face of the company being the highest sellers of their goods and services, for which the company must create an organizational culture with time, persistence and perseverance.
The research methodology was deductive including interviews with experts on the topic of service as well as our own experience in services and trade and industry companies.
In this way it was possible to establish a set of principles and conduct rules the human talent must have in the organization to be recognized as a strong culture of service company
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
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- Lowenstein Michael G.
- Lowry Stephen
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- Lu Lingfeng
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- Lucier Raymond L.
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- Madabhushi Ramki
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- Nwokenkwo Stanley
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- Sonnhammer Erik
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- Stallings Raymond I.
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- Subramanian Sandhya
- Sudbrak Ralf
- Sugnet Charles W.
- Sulston John
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- Sun Min
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- Sun Yu
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- Sutherland Robert D.
- Sutton Angelica E.
- Svatek Amanda F.
- Svetz Jessica
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- Tian Chaoguang
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- Tice Hope
- Tighe Damon
- Tin-Wollam Aye M.
- Tinsley Emma
- Tochigi Miwako
- Togashi Naoko
- Tomizawa Iori
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- Un Chun
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- Wright Rita A.
- Wu Chungen
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- Zhang Haiqing
- Zhang Haiqing
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- Zhang Hongbo
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- Zhang Jingjing
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- Zhang Xianglin
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- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
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- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Search for single production of vector-like quarks decaying into Wb in pp collisions at s=8 TeV with the ATLAS detector
- Author
- Abbott Brad
- Abdallah Jalal
- Abdinov Ovsat
- Abeloos Baptiste
- Aben Rosemarie
- Abolins Maris
- AbouZeid Ossama
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby Sami
- Adamczyk Leszek
- Adams David
- Adelman Jahred
- Adomeit Stefanie
- Adye Tim
- Affolder Tony
- Agatonovic-Jovin Tatjana
- Agricola Johannes
- Aguilar-Saavedra Juan Anton
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akerstedt Henrik
- Akimov Andrei
- Alberghi Gian Luigi
- Albert Justin
- Albrand Solveig
- Alconada Verzini Maria Jose
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Alimonti Gianluca
- Alio Lion
- Alison John
- Alkire Steven Pat
- Allbrooke Benedict
- Allen Benjamin W
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazi
- Amadio Brian Thom
- Amako Katsuya
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana Pat
- Amorim Antonio
- Amoroso Simone
- Amram Nir
- Amundsen Glenn
- Anastopoulos Christos
- Ancu Lucian Ste
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders Gabriel
- Anders John Kenne
- Anderson Kelby
- Andreazza Attilio
- Andrei George Vic
- Angelidakis Stylianos
- Angelozzi Ivan
- Anger Philipp
- Angerami Aaron
- Anghinolfi Francis
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antonelli Mario
- Antonov Alexey
- Antos Jaroslav
- Anulli Fabio
- Aoki Masato
- Aperio Bella Ludovica
- Arabidze Giorgi
- Arai Yasuo
- Araque Juan Pedro
- Arce Ayana
- Arduh Francisco
- Arguin Jean-Franc
- Argyropoulos Spyridon
- Arik Metin
- Armbruster Aaron Jame
- Arnaez Olivier
- Arnold Hannah
- Arratia Miguel
- Arslan Ozan
- Artamonov Andrei
- Artoni Giacomo
- Artz Sebastian
- Asai Shoji
- Asbah Nedaa
- Ashkenazi Adi
- Asquith Lily
- Assamagan Ketevi
- Astalos Robert
- Atkinson Markus
- Atlay Naim Bora
- Augsten Kamil
- Avolio Giuseppe
- Axen Bradley
- Ayoub Mohamad Ka
- Azuelos Georges
- Baak Max
- Baas Alessandra
- Baca Matthew Jo
- Bachacou Henri
- Bachas Konstantin
- Backes Moritz
- Backhaus Malte
- Bagiacchi Paolo
- Bagnaia Paolo
- Bai Yu
- Baines John
- Baker Oliver Kei
- Baldin Evgenii
- Balek Petr
- Balestri Thomas
- Balli Fabrice
- Balunas William Ke
- Banas Elzbieta
- Banerjee Swagato
- Bannoura Arwa A E
- Barak Liron
- Barberio Elisabetta
- Barberis Dario
- Barbero Marlon
- Barillari Teresa
- Barisonzi Marcello
- Barklow Timothy
- Barlow Nick
- Barnes Sarah Loui
- Barnett Bruce
- Barnett Michael
- Barnovska Zuzana
- Baroncelli Antonio
- Barone Gaetano
- Barr Alan
- Barranco Navarro Laura
- Barreiro Guimarães da Costa João
- Barreiro Fernando
- Barros do Vale Maria Alin
- Bartoldus Rainer
- Barton Adam Edwar
- Bartos Pavol
- Basalaev Artem
- Bassalat Ahmed
- Basye Austin
- Bates Richard
- Batista Santiago J
- Batley Richard
- Battaglia Marco
- Bauce Matteo
- Bauer Florian
- Bawa Harinder S
- Beacham James Bake
- Beattie Michael Da
- Beau Tristan
- Beauchemin Pierre-Hug
- Beccherle Roberto
- Bechtle Philip
- Beck Hans~Peter
- Becker Kathrin
- Becker Maurice
- Beckingham Matthew
- Becot Cyril
- Beddall Andrew
- Beddall Ayda
- Bednyakov Vadim
- Bedognetti Matteo
- Bee Christophe
- Beemster Lars
- Beermann Thomas
- Begel Michael
- Behr Janna Kath
- Belanger-Champagne Camille
- Bell William
- Bella Gideon
- Bellagamba Lorenzo
- Bellerive Alain
- Bellomo Massimilia
- Belotskiy Konstantin
- Beltramello Olga
- Benary Odette
- Benchekroun Driss
- Bender Michael
- Bendtz Katarina
- Benekos Nektarios
- Benhammou Yan
- Benhar Noccioli Eleonora
- Benitez Garcia Jorge-Arma
- Benjamin Douglas
- Bensinger James
- Bentvelsen Stan
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- Beringer Jürg
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- Berry Tracey
- Berta Peter
- Bertella Claudia
- Bertoli Gabriele
- Bertolucci Federico
- Bertsche Carolyn
- Bertsche David
- Besjes Geert-Jan
- Bessidskaia Bylund Olga
- Bessner Martin Flo
- Besson Nathalie
- Betancourt Christophe
- Bethke Siegfried
- Bevan Adrian Joh
- Bhimji Wahid
- Bianchi Riccardo-M
- Bianchini Louis
- Bianco Michele
- Biebel Otmar
- Biedermann Dustin
- Biesuz Nicolo Vla
- Biglietti Michela
- Bilbao De Mendizabal Javier
- Bilokon Halina
- Bindi Marcello
- Binet Sebastien
- Bingul Ahmet
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- Biondi Silvia
- Bjergaard David Mart
- Black Curtis
- Black James
- Black Kevin
- Blackburn Daniel
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- Blanchard Jean-Bapti
- Blanco Jacobo Eze
- Blazek Tomas
- Bloch Ingo
- Blocker Craig
- Blum Walter
- Blumenschein Ulrike
- Blunier Sylvain
- Bobbink Gerjan
- Bobrovnikov Victor
- Bocchetta Simona Ser
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- Boehler Michael
- Boerner Daniela
- Bogaerts Joannes An
- Bogavac Danijela
- Bogdanchikov Alexander
- Bohm Christian
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- Bold Tomasz
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- Boonekamp Maarten
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- Bouhova-Thacker Evelina Va
- Boumediene Djamel Edd
- Bourdarios Claire
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- Braun Helmut
- Breaden Madden William Dm
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- Brooks Timothy
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- Brost Elizabeth
- Bruckman de Renstrom Pawel
- Bruncko Dusan
- Bruneliere Renaud
- Bruni Alessia
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- Brunt Benjamin
- Bruschi Marco
- Bruscino Nello
- Bryant Patrick
- Bryngemark Lene
- Buanes Trygve
- Buat Quentin
- Buchholz Peter
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- Budagov Ioulian
- Buehrer Felix
- Bugge Lars
- Bugge Magnar Kop
- Bulekov Oleg
- Bullock Daniel
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- Burghgrave Blake
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- Buttinger William
- Buzatu Adrian
- Buzykaev Aleksey
- Büscher Daniel
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- Cabrera Urbán Susana
- Caforio Davide
- Cairo Valentina
- Cakir Orhan
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- Calderini Giovanni
- Calfayan Philippe
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- Calvet David
- Calvet Samuel
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- Camacho Toro Reina
- Camarda Stefano
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- Caminal Armadans Roger
- Camincher Clement
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- Cardarelli Roberto
- Cardillo Fabio
- Carli Tancredi
- Carlino Gianpaolo
- Carminati Leonardo
- Caron Sascha
- Carquin Edson
- Carrillo-Montoya German D
- Carter Janet
- Carvalho João
- Casadei Diego
- Casado Maria Pila
- Casolino Mirkoanton
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- Chafaq Aziz
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- Chalupkova Ina
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- Chapman John Derek
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- Che Siinn
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- Chegwidden Andrew
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- Cheplakov Alexander
- Cheremushkina Evgenia
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- Chernyatin Valeriy
- Cheu Elliott
- Chevalier Laurent
- Chiarella Vitaliano
- Chiarelli Giorgio
- Chiodini Gabriele
- Chisholm Andrew
- Chislett Rebecca Th
- Chitan Adrian
- Chizhov Mihail
- Choi Kyungeon
- Chouridou Sofia
- Chow Bonnie Kar
- Christodoulou Valentinos
- Chromek-Burckhart Doris
- Chudoba Jiri
- Chuinard Annabelle
- Chwastowski Janusz
- Chytka Ladislav
- Ciapetti Guido
- Ciftci Abbas Kena
- Cinca Diane
- Cindro Vladimir
- Cioara Irina Anto
- Ciocio Alessandra
- Cirotto Francesco
- Citron Zvi Hirsh
- Ciubancan Mihai
- Clark Allan G
- Clark Brian Lee
- Clark Philip Jam
- Clarke Robert
- Clement Christophe
- Coadou Yann
- Cobal Marina
- Coccaro Andrea
- Cochran James H
- Coffey Laurel
- Colasurdo Luca
- Cole Brian
- Cole Stephen
- Colijn Auke-Piete
- Collot Johann
- Colombo Tommaso
- Compostella Gabriele
- Conde Muiño Patricia
- Coniavitis Elias
- Connell Simon Henr
- Connelly Ian
- Consorti Valerio
- Constantinescu Serban
- Conta Claudio
- Conti Geraldine
- Conventi Francesco
- Cooke Mark
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- Cornelissen Thijs
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- Corriveau Francois
- Corso-Radu Alina
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- Cortiana Giorgio
- Costa Giuseppe
- Costa María Jos
- Costanzo Davide
- Cottin Giovanna
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- Cribbs Wayne Alle
- Crispin Ortuzar Mireia
- Cristinziani Markus
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- Crépé-Renaudin Sabine
- Cuhadar Donszelmann Tulay
- Cummings Jane
- Curatolo Maria
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- Czirr Hendrik
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- Cúth Jakub
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- de Asmundis Riccardo
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- Youssef Saul
- Yu David Ren-
- Yu Jaehoon
- Yu Jiaming
- Yu Jie
- Yuan Li
- Yuen Stephanie
- Yusuff Imran
- Zabinski Bartlomiej
- Zaidan Remi
- Zaitsev Alexander
- Zakharchuk Nataliia
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanello Lucia
- Zanzi Daniele
- Zeitnitz Christian
- Zeman Martin
- Zemla Andrzej
- Zeng Jian Cong
- Zeng Qi
- Zengel Keith
- Zenin Oleg
- Zerwas Dirk
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Guangyi
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Rui
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhong Jiahang
- Zhou Bing
- Zhou Chen
- Zhou Lei
- Zhou Li
- Zhou Mingliang
- Zhou Ning
- Zhu Cheng Guan
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- zur Nedden Martin
- Zurzolo Giovanni
- Zwalinski Lukasz
- Åkesson Torsten Pa
- Åsman Barbro
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 08/08/2016
- Field of study
Measurement of the charge asymmetry in top-quark pair production in the lepton-plus-jets final state in pp collision data at s=8TeV with the ATLAS detector
- Author
- Abbott Brad
- Abdallah Jalal
- Abdinov Ovsat
- Aben Rosemarie
- Abolins Maris
- AbouZeid Ossama
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby Sami
- Adamczyk Leszek
- Adams David
- Adelman Jahred
- Adomeit Stefanie
- Adye Tim
- Affolder Tony
- Agatonovic-Jovin Tatjana
- Agricola Johannes
- Aguilar-Saavedra Juan Anton
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akerstedt Henrik
- Akimov Andrei
- Alberghi Gian Luigi
- Albert Justin
- Albrand Solveig
- Alconada Verzini Maria Jose
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Alimonti Gianluca
- Alio Lion
- Alison John
- Alkire Steven Pat
- Allbrooke Benedict
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Altheimer Andrew Dav
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazi
- Amadio Brian Thom
- Amako Katsuya
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana Pat
- Amorim Antonio
- Amoroso Simone
- Amram Nir
- Amundsen Glenn
- Anastopoulos Christos
- Ancu Lucian Ste
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders Gabriel
- Anders John Kenne
- Anderson Kelby
- Andreazza Attilio
- Andrei George Vic
- Angelidakis Stylianos
- Angelozzi Ivan
- Anger Philipp
- Angerami Aaron
- Anghinolfi Francis
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antonelli Mario
- Antonov Alexey
- Antos Jaroslav
- Anulli Fabio
- Aoki Masato
- Aperio Bella Ludovica
- Arabidze Giorgi
- Arai Yasuo
- Araque Juan Pedro
- Arce Ayana
- Arduh Francisco
- Arguin Jean-Franc
- Argyropoulos Spyridon
- Arik Metin
- Armbruster Aaron Jame
- Arnaez Olivier
- Arnold Hannah
- Arratia Miguel
- Arslan Ozan
- Artamonov Andrei
- Artoni Giacomo
- Asai Shoji
- Asbah Nedaa
- Ashkenazi Adi
- Asquith Lily
- Assamagan Ketevi
- Astalos Robert
- Atkinson Markus
- Atlay Naim Bora
- Augsten Kamil
- Aurousseau Mathieu
- Avolio Giuseppe
- Axen Bradley
- Ayoub Mohamad Ka
- Azuelos Georges
- Baak Max
- Baas Alessandra
- Baca Matthew Jo
- Bacci Cesare
- Bachacou Henri
- Bachas Konstantin
- Backes Moritz
- Backhaus Malte
- Bagiacchi Paolo
- Bagnaia Paolo
- Bai Yu
- Bain Travis
- Baines John
- Baker Oliver Kei
- Baldin Evgenii
- Balek Petr
- Balestri Thomas
- Balli Fabrice
- Balunas William Ke
- Banas Elzbieta
- Banerjee Swagato
- Bannoura Arwa A E
- Barak Liron
- Barberio Elisabetta
- Barberis Dario
- Barbero Marlon
- Barillari Teresa
- Barisonzi Marcello
- Barklow Timothy
- Barlow Nick
- Barnes Sarah Loui
- Barnett Bruce
- Barnett Michael
- Barnovska Zuzana
- Baroncelli Antonio
- Barone Gaetano
- Barr Alan
- Barreiro Guimarães da Costa João
- Barreiro Fernando
- Barros do Vale Maria Alin
- Bartoldus Rainer
- Barton Adam Edwar
- Bartos Pavol
- Basalaev Artem
- Bassalat Ahmed
- Basye Austin
- Bates Richard
- Batista Santiago J
- Batley Richard
- Battaglia Marco
- Bauce Matteo
- Bauer Florian
- Bawa Harinder S
- Beacham James Bake
- Beattie Michael Da
- Beau Tristan
- Beauchemin Pierre-Hug
- Beccherle Roberto
- Bechtle Philip
- Beck Hans Peter
- Becker Kathrin
- Becker Maurice
- Beckingham Matthew
- Becot Cyril
- Beddall Andrew
- Beddall Ayda
- Bednyakov Vadim
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- Beemster Lars
- Beermann Thomas
- Begel Michael
- Behr Janna Kath
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- Bella Gideon
- Bellagamba Lorenzo
- Bellerive Alain
- Bellomo Massimilia
- Belotskiy Konstantin
- Beltramello Olga
- Benary Odette
- Benchekroun Driss
- Bender Michael
- Bendtz Katarina
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- Benhammou Yan
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- Bertsche David
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- Bessidskaia Bylund Olga
- Bessner Martin Flo
- Besson Nathalie
- Betancourt Christophe
- Bethke Siegfried
- Bevan Adrian Joh
- Bhimji Wahid
- Bianchi Riccardo-M
- Bianchini Louis
- Bianco Michele
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- Biedermann Dustin
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- Grinstein Sebastian
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- Grivaz Jean-Franc
- Grohs Johannes P
- Grohsjean Alexander
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- Gutierrez Phillip
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- Gwilliam Carl
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- Haas Andy
- Haber Carl
- Hadavand Haleh Khan
- Haddad Nacim
- Haefner Petra
- Hageböck Stephan
- Hajduk Zbigniew
- Hakobyan Hrachya
- Haleem Mahsana
- Haley Joseph
- Hall David
- Halladjian Garabed
- Hallewell Gregory Da
- Hamacher Klaus
- Hamal Petr
- Hamano Kenji
- Hamilton Andrew
- Hamity Guillermo
- Hamnett Phillip Ge
- Han Liang
- Hanagaki Kazunori
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- Wanotayaroj Chaowaroj
- Warburton Andreas
- Ward Patricia
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- Watson Alan
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- Watson Miriam
- Watts Gordon
- Watts Stephen
- Waugh Ben
- Webb Samuel
- Weber Michele
- Weber Stefan Wol
- Webster Jordan S
- Weidberg Anthony
- Weinert Benjamin
- Weingarten Jens
- Weiser Christian
- Weits Hartger
- Wells Phillippa
- Wenaus Torre
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- Whiteson Daniel
- Wickens Fred
- Wiedenmann Werner
- Wielers Monika
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- Wiglesworth Craig
- Wiik-Fuchs Liv Antje
- Wildauer Andreas
- Wilkens Henric Geo
- Williams Hugh
- Williams Sarah
- Willis Christophe
- Willocq Stephane
- Wilson Alan
- Wilson John
- Wingerter-Seez Isabelle
- Winklmeier Frank
- Winter Benedict T
- Wittgen Matthias
- Wittkowski Josephine
- Wollstadt Simon Jako
- Wolter Marcin Wla
- Wolters Helmut
- Wosiek Barbara
- Wotschack Jorg
- Woudstra Martin
- Wozniak Krzysztof
- Wu Mengqing
- Wu Miles
- Wu Sau Lan
- Wu Xin
- Wu Yusheng
- Wyatt Terry Rich
- Wynne Benjamin
- Xella Stefania
- Xu Da
- Xu Lailin
- Yabsley Bruce
- Yacoob Sahal
- Yakabe Ryota
- Yamada Miho
- Yamaguchi Daiki
- Yamaguchi Yohei
- Yamamoto Akira
- Yamamoto Shimpei
- Yamanaka Takashi
- Yamauchi Katsuya
- Yamazaki Yuji
- Yan Zhen
- Yang Haijun
- Yang Hongtao
- Yang Yi
- Yao Weiming
- Yap Yee Chinn
- Yasu Yoshiji
- Yatsenko Elena
- Yau Wong Kaven Henr
- Ye Jingbo
- Ye Shuwei
- Yeletskikh Ivan
- Yen Andy L
- Yildirim Eda
- Yorita Kohei
- Yoshida Rikutaro
- Yoshihara Keisuke
- Young Charles
- Young Christophe
- Youssef Saul
- Yu David Ren-
- Yu Jaehoon
- Yu Jiaming
- Yu Jie
- Yuan Li
- Yuen Stephanie
- Yurkewicz Adam
- Yusuff Imran
- Zabinski Bartlomiej
- Zaidan Remi
- Zaitsev Alexander
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanello Lucia
- Zanzi Daniele
- Zeitnitz Christian
- Zeman Martin
- Zemla Andrzej
- Zeng Qi
- Zengel Keith
- Zenin Oleg
- Zerwas Dirk
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Guangyi
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhong Jiahang
- Zhou Bing
- Zhou Chen
- Zhou Lei
- Zhou Li
- Zhou Mingliang
- Zhou Ning
- Zhu Cheng Guan
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- zur Nedden Martin
- Zurzolo Giovanni
- Zwalinski Lukasz
- Åkesson Torsten Pa
- Åsman Barbro
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 19/02/2016
- Field of study
ATLAS Run 1 searches for direct pair production of third-generation squarks at the Large Hadron Collider
- Author
- Abbott Brad
- Abdallah Jalal
- Abdinov Ovsat
- Aben Rosemarie
- Abolins Maris
- AbouZeid Ossama
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby Sami
- Adamczyk Leszek
- Adams David
- Adelman Jahred
- Adomeit Stefanie
- Adye Tim
- Affolder Tony
- Agatonovic-Jovin Tatjana
- Agricola Johannes
- Aguilar-Saavedra Juan Anton
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akerstedt Henrik
- Akimov Andrei
- Alberghi Gian Luigi
- Albert Justin
- Albrand Solveig
- Alconada Verzini Maria Jose
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Alimonti Gianluca
- Alio Lion
- Alison John
- Alkire Steven Pat
- Allbrooke Benedict
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Altheimer Andrew Dav
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazi
- Amadio Brian Thom
- Amako Katsuya
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana Pat
- Amorim Antonio
- Amoroso Simone
- Amram Nir
- Amundsen Glenn
- Anastopoulos Christos
- Ancu Lucian Ste
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders Gabriel
- Anders John Kenne
- Anderson Kelby
- Andreazza Attilio
- Andrei George Vic
- Angelidakis Stylianos
- Angelozzi Ivan
- Anger Philipp
- Angerami Aaron
- Anghinolfi Francis
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antonelli Mario
- Antonov Alexey
- Antos Jaroslav
- Anulli Fabio
- Aoki Masato
- Aperio Bella Ludovica
- Arabidze Giorgi
- Arai Yasuo
- Araque Juan Pedro
- Arce Ayana
- Arduh Francisco
- Arguin Jean-Franc
- Argyropoulos Spyridon
- Arik Metin
- Armbruster Aaron Jame
- Arnaez Olivier
- Arnal Vanessa
- Arnold Hannah
- Arratia Miguel
- Arslan Ozan
- Artamonov Andrei
- Artoni Giacomo
- Asai Shoji
- Asbah Nedaa
- Ashkenazi Adi
- Asquith Lily
- Assamagan Ketevi
- Astalos Robert
- Atkinson Markus
- Atlay Naim Bora
- Auerbach Benjamin
- Augsten Kamil
- Aurousseau Mathieu
- Avolio Giuseppe
- Axen Bradley
- Ayoub Mohamad Ka
- Azuelos Georges
- Baak Max
- Baas Alessandra
- Baca Matthew Jo
- Bacci Cesare
- Bachacou Henri
- Bachas Konstantin
- Backes Moritz
- Backhaus Malte
- Bagiacchi Paolo
- Bagnaia Paolo
- Bai Yu
- Bain Travis
- Baines John
- Baker Oliver Kei
- Baldin Evgenii
- Balek Petr
- Balestri Thomas
- Balli Fabrice
- Banas Elzbieta
- Banerjee Swagato
- Bannoura Arwa A E
- Bansil Hardeep Si
- Barak Liron
- Barberio Elisabetta
- Barberis Dario
- Barbero Marlon
- Barillari Teresa
- Barisonzi Marcello
- Barklow Timothy
- Barlow Nick
- Barnes Sarah Loui
- Barnett Bruce
- Barnett Michael
- Barnovska Zuzana
- Baroncelli Antonio
- Barone Gaetano
- Barr Alan
- Barreiro Guimarães da Costa João
- Barreiro Fernando
- Barros do Vale Maria Alin
- Bartoldus Rainer
- Barton Adam Edwar
- Bartos Pavol
- Basalaev Artem
- Bassalat Ahmed
- Basye Austin
- Bates Richard
- Batista Santiago J
- Batley Richard
- Battaglia Marco
- Bauce Matteo
- Bauer Florian
- Bawa Harinder S
- Beacham James Bake
- Beattie Michael Da
- Beau Tristan
- Beauchemin Pierre-Hug
- Beccherle Roberto
- Bechtle Philip
- Beck Hans Peter
- Becker Kathrin
- Becker Maurice
- Becker Sebastian
- Beckingham Matthew
- Becot Cyril
- Beddall Andrew
- Beddall Ayda
- Bednyakov Vadim
- Bee Christophe
- Beemster Lars
- Beermann Thomas
- Begel Michael
- Behr Janna Kath
- Belanger-Champagne Camille
- Bell William
- Bella Gideon
- Bellagamba Lorenzo
- Bellerive Alain
- Bellomo Massimilia
- Belotskiy Konstantin
- Beltramello Olga
- Benary Odette
- Benchekroun Driss
- Bender Michael
- Bendtz Katarina
- Benekos Nektarios
- Benhammou Yan
- Benhar Noccioli Eleonora
- Benitez Garcia Jorge-Arma
- Benjamin Douglas
- Bensinger James
- Bentvelsen Stan
- Beresford Lydia
- Beretta Matteo
- Berge David
- Bergeaas Kuutmann Elin
- Berger Nicolas
- Berghaus Frank
- Beringer Jürg
- Bernard Clare
- Bernard Nathan Rog
- Bernius Catrin
- Bernlochner Florian Ur
- Berry Tracey
- Berta Peter
- Bertella Claudia
- Bertoli Gabriele
- Bertolucci Federico
- Bertsche Carolyn
- Bertsche David
- Besana Maria Ilar
- Besjes Geert-Jan
- Bessidskaia Bylund Olga
- Bessner Martin Flo
- Besson Nathalie
- Betancourt Christophe
- Bethke Siegfried
- Bevan Adrian Joh
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- Graber Lars
- Grabowska-Bold Iwona
- Gradin Per Olov J
- Grafström Per
- Grahn Karl-Johan
- Gramling Johanna
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- Grenier Philippe
- Griffiths Justin
- Grillo Alexander
- Grimm Kathryn
- Grinstein Sebastian
- Gris Philippe L
- Grivaz Jean-Franc
- Grohs Johannes P
- Grohsjean Alexander
- Gross Eilam
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- Hasegawa Satoshi
- Hasegawa Yoji
- Hasib A
- Hassani Samira
- Haug Sigve
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- Hawkings Richard Jo
- Hawkins Anthony Da
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- Kareem Mohammad J
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- Soni Nitesh
- Sood Alexander
- Sopczak Andre
- Sopko Bruno
- Sopko Vit
- Sorin Veronica
- Sosa David
- Sosebee Mark
- Sotiropoulou Calliope L
- Soualah Rachik
- Soukharev Andrey
- South David
- Sowden Benjamin
- Spagnolo Stefania
- Spalla Margherita
- Spanò Francesco
- Spearman William Ro
- Sperlich Dennis
- Spettel Fabian
- Spighi Roberto
- Spigo Giancarlo
- Spiller Laurence A
- Spousta Martin
- Spreitzer Teresa
- St Denis Richard Da
- Staerz Steffen
- Stahlman Jonathan
- Stamen Rainer
- Stamm Soren
- Stanecka Ewa
- Stanescu Cristian
- Stanescu-Bellu Madalina
- Stanitzki Marcel Mic
- Stapnes Steinar
- Starchenko Evgeny
- Stark Jan
- Staroba Pavel
- Starovoitov Pavel
- Staszewski Rafal
- Stavina Pavel
- Steinberg Peter
- Stelzer Bernd
- Stelzer Harald Joe
- Stelzer-Chilton Oliver
- Stenzel Hasko
- Stewart Graeme
- Stillings Jan Andre
- Stockton Mark
- Stoebe Michael
- Stoicea Gabriel
- Stolte Philipp
- Stonjek Stefan
- Stradling Alden
- Straessner Arno
- Stramaglia Maria Elen
- Strandberg Jonas
- Strandberg Sara
- Strandlie Are
- Strauss Emanuel
- Strauss Michael
- Strizenec Pavol
- Strom David
- Stroynowski Ryszard
- Strubig Antonia
- Ströhmer Raimund
- Stucci Stefania A
- Stugu Bjarne
- Styles Nicholas A
- Su Dong
- Su Jun
- Subramaniam Rajivaloch
- Succurro Antonella
- Sugaya Yorihito
- Suhr Chad
- Suk Michal
- Sulin Vladimir
- Sultansoy Saleh
- Sumida Toshi
- Sun Siyuan
- Sun Xiaohu
- Sundermann Jan Erik
- Suruliz Kerim
- Susinno Giancarlo
- Sutton Mark
- Suzuki Shota
- Svatos Michal
- Swedish Stephen
- Swiatlowski Maximilian
- Sykora Ivan
- Sykora Tomas
- Sánchez Javier
- Ta Duc
- Taccini Cecilia
- Tackmann Kerstin
- Taenzer Joe
- Taffard Anyes
- Tafirout Reda
- Taiblum Nimrod
- Takai Helio
- Takashima Ryuichi
- Takeda Hiroshi
- Takeshita Tohru
- Takubo Yosuke
- Talby Mossadek
- Talyshev Alexey
- Tam Jason
- Tan Kong Guan
- Tanaka Junichi
- Tanaka Reisaburo
- Tanaka Shuji
- Tannenwald Benjamin B
- Tannoury Nancy
- Tapprogge Stefan
- Tarem Shlomit
- Tarrade Fabien
- Tartarelli Giuseppe F
- Tas Petr
- Tasevsky Marek
- Tashiro Takuya
- Tassi Enrico
- Tavares Delgado Ademar
- Tayalati Yahya
- Taylor Frank
- Taylor Geoffrey
- Taylor Wendy
- Teischinger Florian Al
- Teixeira Dias Castanheira Matilde
- Teixeira-Dias Pedro
- Temming Kim Katrin
- Ten Kate Herman
- Teng Ping-Kun
- Teoh Jia Jian
- Tepel Fabian-Phi
- Terada Susumu
- Terashi Koji
- Terron Juan
- Terzo Stefano
- Testa Marianna
- Teuscher Richard
- Theveneaux-Pelzer Timothée
- Thomas Juergen
- Thomas-Wilsker Joshuha
- Thompson Emily
- Thompson Paul
- Thompson Ray
- Thompson Stan
- Thomsen Lotte Ansg
- Thomson Evelyn
- Thomson Mark
- Thun Rudolf
- Tibbetts Mark James
- Ticse Torres Royer Edso
- Tikhomirov Vladimir
- Tikhonov Yury
- Timoshenko Sergey
- Tiouchichine Elodie
- Tipton Paul
- Tisserant Sylvain
- Todome Kazuki
- Todorov Theodore
- Todorova-Nova Sharka
- Tojo Junji
- Tokushuku Katsuo
- Tokár Stanislav
- Tollefson Kirsten
- Tolley Emma
- Tomlinson Lee
- Tomoto Makoto
- Tompkins Lauren
- Toms Konstantin
- Torrence Eric
- Torres Heberth
- Torró Pastor Emma
- Toth Jozsef
- Touchard Francois
- Tovey Daniel
- Trefzger Thomas
- Tremblet Louis
- Tricoli Alessandro
- Trigger Isabel Mar
- Trincaz-Duvoid Sophie
- Tripiana Martin
- Trischuk William
- Trocmé Benjamin
- Troncon Clara
- Trottier-McDonald Michel
- Trovatelli Monica
- True Patrick
- Truong Loan
- Trzebinski Maciej
- Trzupek Adam
- Tsarouchas Charilaos
- Tseng Jeffrey
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- Tsionou Dimitra
- Tsipolitis Georgios
- Tsirintanis Nikolaos
- Tsiskaridze Shota
- Tsiskaridze Vakhtang
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- Tupputi Salvatore
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- Tylmad Maja
- Tyndel Mike
- Ueda Ikuo
- Ueno Ryuichi
- Ughetto Michael
- Ugland Maren
- Uhlenbrock Mathias
- Ukegawa Fumihiko
- Unal Guillaume
- Undrus Alexander
- Unel Gokhan
- Ungaro Francesca
- Unno Yoshinobu
- Unverdorben Christophe
- Urban Jozef
- Urquijo Phillip
- Urrejola Pedro
- Usai Giulio
- Usanova Anna
- Vacavant Laurent
- Vacek Vaclav
- Vachon Brigitte
- Valderanis Chrysostom
- Valencic Nika
- Valentinetti Sara
- Valero Alberto
- Valery Loic
- Valkar Stefan
- Valladolid Gallego Eva
- Vallecorsa Sofia
- Valls Ferrer Juan Anton
- Van Den Wollenberg Wouter
- Van Der Deijl Pieter
- van der Geer Rogier
- van der Graaf Harry
- Van Der Leeuw Robin
- van Eldik Niels
- van Gemmeren Peter
- Van Nieuwkoop Jacobus
- van Vulpen Ivo
- van Woerden Marius Cor
- Vanadia Marco
- Vandelli Wainer
- Vanguri Rami
- Vaniachine Alexandre
- Vannucci Francois
- Vardanyan Gagik
- Vari Riccardo
- Varnes Erich
- Varol Tulin
- Varouchas Dimitris
- Vartapetian Armen
- Varvell Kevin
- Vazeille Francois
- Vazquez Schroeder Tamara
- Veatch Jason
- Veloce Laurelle M
- Veloso Filipe
- Velz Thomas
- Veneziano Stefano
- Ventura Andrea
- Ventura Daniel
- Venturi Manuela
- Venturi Nicola
- Venturini Alessio
- Vercesi Valerio
- Verducci Monica
- Verkerke Wouter
- Vermeulen Jos
- Vest Anja
- Vetterli Michel
- Viazlo Oleksandr
- Vichou Irene
- Vickey Boeriu Oana Elena
- Vickey Trevor
- Viehhauser Georg
- Viel Simon
- Vigne Ralph
- Villa Mauro
- Villaplana Perez Miguel
- Vilucchi Elisabetta
- Vincter Manuella
- Vinogradov Vladimir
- Vivarelli Iacopo
- Vives Vaque Francesc
- Vlachos Sotirios
- Vladoiu Dan
- Vlasak Michal
- Vogel Marcelo
- Vokac Petr
- Volpi Guido
- Volpi Matteo
- von der Schmitt Hans
- von Radziewski Holger
- von Toerne Eckhard
- Vorobel Vit
- Vorobev Konstantin
- Vos Marcel
- Voss Rudiger
- Vossebeld Joost
- Vranjes Milosavljevic Marija
- Vranjes Nenad
- Vrba Vaclav
- Vreeswijk Marcel
- Vuillermet Raphael
- Vukotic Ilija
- Vykydal Zdenek
- Wagner Peter
- Wagner Wolfgang
- Wahlberg Hernan
- Wahrmund Sebastian
- Wakabayashi Jun
- Walder James
- Walker Rodney
- Walkowiak Wolfgang
- Wang Chao
- Wang Fuquan
- Wang Haichen
- Wang Hulin
- Wang Jike
- Wang Jin
- Wang Kuhan
- Wang Rui
- Wang Song-Ming
- Wang Tan
- Wang Tingting
- Wang Xiaoxiao
- Wanotayaroj Chaowaroj
- Warburton Andreas
- Ward Patricia
- Wardrope David Robe
- Warsinsky Markus
- Washbrook Andrew
- Wasicki Christoph
- Watkins Peter
- Watson Alan
- Watson Ian
- Watson Miriam
- Watts Gordon
- Watts Stephen
- Waugh Ben
- Webb Samuel
- Weber Michele
- Weber Stefan Wol
- Webster Jordan S
- Weidberg Anthony
- Weinert Benjamin
- Weingarten Jens
- Weiser Christian
- Weits Hartger
- Wells Phillippa
- Wenaus Torre
- Wengler Thorsten
- Wenig Siegfried
- Wermes Norbert
- Werner Matthias
- Werner Per
- Wessels Martin
- Wetter Jeffrey
- Whalen Kathleen
- Wharton Andrew Mar
- White Andrew
- White Martin
- White Ryan
- White Sebastian
- Whiteson Daniel
- Wickens Fred
- Wiedenmann Werner
- Wielers Monika
- Wienemann Peter
- Wiglesworth Craig
- Wiik-Fuchs Liv Antje
- Wildauer Andreas
- Wilkens Henric Geo
- Williams Hugh
- Williams Sarah
- Willis Christophe
- Willocq Stephane
- Wilson Alan
- Wilson John
- Wingerter-Seez Isabelle
- Winklmeier Frank
- Winter Benedict T
- Wittgen Matthias
- Wittkowski Josephine
- Wollstadt Simon Jako
- Wolter Marcin Wla
- Wolters Helmut
- Wosiek Barbara
- Wotschack Jorg
- Woudstra Martin
- Wozniak Krzysztof
- Wu Mengqing
- Wu Miles
- Wu Sau Lan
- Wu Xin
- Wu Yusheng
- Wyatt Terry Rich
- Wynne Benjamin
- Xella Stefania
- Xu Da
- Xu Lailin
- Yabsley Bruce
- Yacoob Sahal
- Yakabe Ryota
- Yamada Miho
- Yamaguchi Yohei
- Yamamoto Akira
- Yamamoto Shimpei
- Yamanaka Takashi
- Yamauchi Katsuya
- Yamazaki Yuji
- Yan Zhen
- Yang Haijun
- Yang Hongtao
- Yang Yi
- Yao Weiming
- Yasu Yoshiji
- Yatsenko Elena
- Yau Wong Kaven Henr
- Ye Jingbo
- Ye Shuwei
- Yeletskikh Ivan
- Yen Andy L
- Yildirim Eda
- Yorita Kohei
- Yoshida Rikutaro
- Yoshihara Keisuke
- Young Charles
- Young Christophe
- Youssef Saul
- Yu David Ren-
- Yu Jaehoon
- Yu Jiaming
- Yu Jie
- Yuan Li
- Yuen Stephanie
- Yurkewicz Adam
- Yusuff Imran
- Zabinski Bartlomiej
- Zaidan Remi
- Zaitsev Alexander
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanello Lucia
- Zanzi Daniele
- Zeitnitz Christian
- Zeman Martin
- Zemla Andrzej
- Zengel Keith
- Zenin Oleg
- Zerwas Dirk
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhong Jiahang
- Zhou Bing
- Zhou Chen
- Zhou Lei
- Zhou Li
- Zhou Ning
- Zhu Cheng Guan
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- zur Nedden Martin
- Zurzolo Giovanni
- Zwalinski Lukasz
- Åkesson Torsten Pa
- Åsman Barbro
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 29/10/2015
- Field of study
Efficacy and safety of the CVnCoV SARS-CoV-2 mRNA vaccine candidate in ten countries in Europe and Latin America (HERALD): a randomised, observer-blinded, placebo-controlled, phase 2b/3 trial
- Author
- Aguirre-García Gloria Mayela
- Ahuad Guerrero Rodolfo Andres
- Ahuad Guerrero Rodolfo Andrés
- Arana-Arri Eunate
- Arancibia Luna Lesly Angela
- Arias Hoo Dommie Janneth
- Aroca Martinez Gustavo Jose
- Arredondo Saldaña Felipe
- Ascaso del Río Ana
- Balmaceda Maria Pia
- Barrera Perigault Paulo
- Bautista Toloza Leonardo
- Bobat Antonela
- Boersma Wim
- Boggia Bruno Emilio
- Bonten Marc
- Borchowiek Silvina
- Braida Ariel
- Brecx Alain
- Bustinduy Odriozola Maria Jesus
- Camacho Choza Laura Julia
- Camara Anais
- Candelario Rosalba
- Carbajal Paulet Óscar
- Castella Sofia
- Castro Castrezana Laura
- Celis Carlos R.
- Chan Milagros
- Chandler Reynaldo
- Cheatham-Seitz Darline
- Chávez Barón Jaime
- Collazos Lennis Maria Fernanda
- Cornejo Enrique
- Cornejo Rubelio E.
- Corral Gonzalo
- de Bie Jessie
- de Block Eddie Jan Louis
- de Jonge Hanna K.
- de la Flor Carolina
- de Winter Ronald Frank Jacobus
- DeAntonio Rodrigo
- Diaz-Parra Carmen
- Diez Fabián
- Dittrich Ricardo Julio
- Djamin Remco
- Donastorg Yeycy
- Durigan Virginia
- Durán Laviña María Isabel
- Eberts Sandra
- Ecker Lucie
- Escobar Johnny
- Esen Meral
- Espínola Lidia
- Fendel Rolf
- Fernandez Alberto
- Fleischmann Wim Alexander
- Flores Omar
- Foccoli Monica
- Gabor Julian Justin
- Gallego Mikel
- Ganaha Maria Cristina
- Garcia Lopez Carlos Alberto
- García Cruz Johanna Marcela
- García-de-Vicuña Aitor
- Gil Ana I.
- Gonzales Lucy
- González Limón Pablo
- Gorini Nestor
- Granados González María Angélica
- Grandez Castillo Gustavo Alberto
- Grazziani Franco
- Gregoraci Giorgia
- Grobusch Martin P.
- Guardiani Fernando Martin
- Guzman Quintanilla Fernanda
- Guzman Esperanza
- Hammerschlag Icaza Bruno
- Herrera Sanchez Javier
- Hessels Lisa
- Horn Carola
- Hrabar Adrian D.
- Huber Kristina
- Imaz-Ayo Natale
- Junker Helga
- Kimura Alan
- Koehne Erik
- Kreidenweiss Andrea
- Kremsner Peter G.
- Kroidl Arne
- Köhler Carsten
- Ladino González Margot Cecilia
- Lama Javier R.
- Lambert Sandra
- Lanata Claudio F.
- Lantigua Flavia
- Laredo Velasco Leonor
- Larrea Arranz Igor
- Lehmann Clara
- Leroux-Roels Isabel
- Longhi Andrea
- Lovesio Luciano
- Luján Palacios Juan de Dios
- Mann Philipp
- Martella Carolina
- Martinez Avendaño Alejandro
- Martinez-Reséndez Michel Fernando
- Martínez Alcorta Luis Ignacio
- Mastruzzo María
- Matta Aguirre Milagros Erika
- Mayorga Valerie
- Mazara Rosario Sonia
- Mazo Elorza Diana Patricia
- Meijide Susana
- Morales-Oliva Jose
- Nemi Sergio Andrés
- Ochoa Mayra
- Ochoa Theresa J.
- Olmos Vega Jocelyn
- Oostvogels Lidia
- Ortega Dominguez Sandra Janeth
- Pedernera Aldana
- Peña Mendez Lourdes
- Peña Bia
- Peña Moisés
- Piedimonte Fabián C. sar
- Portolés-Pérez Antonio
- Potito Roberto
- Poy Carlos Alberto
- Prieto Pradera I. igo
- Quintini Gianluca
- Ramírez Lamas Suzanne Pamela
- Rebollon Gabriel
- Reyes Fentanes Maria Jose
- Reyes Gilda
- Reynales Londoño Humberto
- Ricalde Sheby A.
- Rios Nogales Luis
- Rivera Mejia Luis Maria
- Rivera Laura
- Rodríguez Ordoñez Paula Andrea
- Rojas Marianela
- Rosario Gomez Nadia
- Ruiz Herrera Vida Veronica
- Ruiz Palacios y Santos Guillermo Miguel
- Ruiz Sergio
- Sanes Fatima
- Santorcuato Ana
- Schnyder Jenny L.
- Schunk Mirjam
- Schönborn-Kellenberger Oliver
- Seibel Tobias
- Sierra Garcia Alexandra
- Solano Mosquera Lina Marianur
- Sáez-Llorens Xavier
- Tartaglione Javier Gerardo
- Thiel Verena
- Torres Almanzar Dania
- Torres Hernandez Daniela
- Torres Quiroz Ivonne Aimee
- Vahrenhorst Dominik
- Valdiviezo Gladys
- van der Sar Simone
- Vanegas Dominguez Beatriz
- Vecchio Claudia
- Vega Orozco Karen Sofia
- Vergara Itziar
- Verstraeten Thomas
- Vico Marisa
- Vidal Jhonny
- Vázquez Saldaña Eduardo Gabriel
- Vázquez Villar Andrea
- Walz Lisa
- Webb Camille María
- Wong t Digna Y.
- Zalatnik Viviana Judith
- Zambrano Ochoa Adriana Pilar
- Zambrano Ortiz José
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/03/2022
- Field of study
Background: Additional safe and efficacious vaccines are needed to control the COVID-19 pandemic. We aimed to analyse the efficacy and safety of the CVnCoV SARS-CoV-2 mRNA vaccine candidate. Methods: HERALD is a randomised, observer-blinded, placebo-controlled, phase 2b/3 clinical trial conducted in 47 centres in ten countries in Europe and Latin America. By use of an interactive web response system and stratification by country and age group (18–60 years and ≥61 years), adults with no history of virologically confirmed COVID-19 were randomly assigned (1:1) to receive intramuscularly either two 0·6 mL doses of CVnCoV containing 12 μg of mRNA or two 0·6 mL doses of 0·9% NaCl (placebo) on days 1 and 29. The primary efficacy endpoint was the occurrence of a first episode of virologically confirmed symptomatic COVID-19 of any severity and caused by any strain from 15 days after the second dose. For the primary endpoint, the trial was considered successful if the lower limit of the CI was greater than 30%. Key secondary endpoints were the occurrence of a first episode of virologically confirmed moderate-to-severe COVID-19, severe COVID-19, and COVID-19 of any severity by age group. Primary safety outcomes were solicited local and systemic adverse events within 7 days after each dose and unsolicited adverse events within 28 days after each dose in phase 2b participants, and serious adverse events and adverse events of special interest up to 1 year after the second dose in phase 2b and phase 3 participants. Here, we report data up to June 18, 2021. The study is registered at ClinicalTrials.gov, NCT04652102, and EudraCT, 2020–003998–22, and is ongoing. Findings: Between Dec 11, 2020, and April 12, 2021, 39 680 participants were enrolled and randomly assigned to receive either CVnCoV (n=19 846) or placebo (n=19 834), of whom 19 783 received at least one dose of CVnCoV and 19 746 received at least one dose of placebo. After a mean observation period of 48·2 days (SE 0·2), 83 cases of COVID-19 occurred in the CVnCoV group (n=12 851) in 1735·29 person-years and 145 cases occurred in the placebo group (n=12 211) in 1569·87 person-years, resulting in an overall vaccine efficacy against symptomatic COVID-19 of 48·2% (95·826% CI 31·0–61·4; p=0·016). Vaccine efficacy against moderate-to-severe COVID-19 was 70·7% (95% CI 42·5–86·1; CVnCoV 12 cases in 1735·29 person-years, placebo 37 cases in 1569·87 person-years). In participants aged 18–60 years, vaccine efficacy against symptomatic disease was 52·5% (95% CI 36·2–64·8; CVnCoV 71 cases in 1591·47 person-years, placebo, 136 cases in 1449·23 person-years). Too few cases occurred in participants aged 61 years or older (CVnCoV 12, placebo nine) to allow meaningful assessment of vaccine efficacy. Solicited adverse events, which were mostly systemic, were more common in CVnCoV recipients (1933 [96·5%] of 2003) than in placebo recipients (1344 [67·9%] of 1978), with 542 (27·1%) CVnCoV recipients and 61 (3·1%) placebo recipients reporting grade 3 solicited adverse events. The most frequently reported local reaction after any dose in the CVnCoV group was injection-site pain (1678 [83·6%] of 2007), with 22 grade 3 reactions, and the most frequently reported systematic reactions were fatigue (1603 [80·0%] of 2003) and headache (1541 [76·9%] of 2003). 82 (0·4%) of 19 783 CVnCoV recipients reported 100 serious adverse events and 66 (0·3%) of 19 746 placebo recipients reported 76 serious adverse events. Eight serious adverse events in five CVnCoV recipients and two serious adverse events in two placebo recipients were considered vaccination-related. None of the fatal serious adverse events reported (eight in the CVnCoV group and six in the placebo group) were considered to be related to study vaccination. Adverse events of special interest were reported for 38 (0·2%) participants in the CVnCoV group and 31 (0·2%) participants in the placebo group. These events were considered to be related to the trial vaccine for 14 (<0·1%) participants in the CVnCoV group and for five (<0·1%) participants in the placebo group. Interpretation: CVnCoV was efficacious in the prevention of COVID-19 of any severity and had an acceptable safety profile. Taking into account the changing environment, including the emergence of SARS-CoV-2 variants, and timelines for further development, the decision has been made to cease activities on the CVnCoV candidate and to focus efforts on the development of next-generation vaccine candidates. Funding: German Federal Ministry of Education and Research and CureVac
Proceedings of the 2017 WAO Symposium on Hot Topics in Allergy: Pediatric & Regulatory Aspects
- Author
- Aarnio Jasmin
- af Ursin Piia
- Al-Hammadi Suleiman
- Albarran Carlos
- Alblooshi Afaf
- Alcocer Christian R.
- Alcover Javier
- Alcover Javier
- Alonso Ana Maria
- Andrade Claudia
- Antipkin Youriy
- Antonova Evgeniya
- Antonova Evgeniya
- Arshad Hasan
- Artesani Maria Cristina
- Artesani Maria Cristina
- Artesani Maria Cristina
- Baalasubramanian Sivasankar
- Bala Nandana
- Banzato Claudia
- Barzylovich Vladyslava
- Baynova Krasimira
- Beitia Juan Maria
- Bekir Suzan
- Belén Mateo Maria
- Benor Shira
- Besednjak-Kocijančič Lilijana
- Bhagwat Ketaki
- Bhattacharya Swati Gupta
- Bhattacharya Swati Gupta
- Biarnés Rib Gemma
- Blohlávková Simona
- Bodhankar Subhash
- Bosque García Montserrat
- Busse William W.
- Capriles Hulett Arnaldo
- Casale Thomas
- Castells Mariana
- Chapman Martin
- Chipps Bradley E.
- Chipps Bradley E.
- Chipps Bradley E.
- Ciucǎ Ioana-Mihaela
- Cárdenas Remedios
- D'Ambrosio Angelo
- Dahdah Lamia
- Dahdah Lamia
- Dahdah Lamia
- Dalal Ilan
- Dall'Oglio Luigi
- De Angelis Papola
- De Aramburu Teresa
- de Vicente Jiménez Talía
- De Vuono Andrea
- Del Chierico Federica
- Del Rio Navarro Blanca Estela
- Ebisawa Motohiro
- Ebisawa Motohiro
- Echeverría Zudaire Luís Angel
- Escobar Bolaños Carolina
- Fabiano Fabiola
- Farhan Abdal Jabbar
- Fernandez Roberto Jose
- Fierro Vincenzo
- Fierro Vincenzo
- Fierro Vincenzo
- Fierro Vincenzo
- Fikri Bahrul
- Fiocchi Alessandro
- Fiocchi Alessandro
- Fiocchi Alessandro
- Flanders Tamar
- García-Domínguez Juan Jesús
- Gaurav Garg
- Gonzalez Victor
- Gonzalez-Reyes Erika
- Gonçalves Alvim Cristina
- Goto Fumiko
- Goyal Rohit
- Griffin Noelle M.
- Gupta Shilpa
- Gutiérrez-Rivas Raquel
- Haanpää Leena
- Hindley James
- Hoshioka Akira
- Hussain Ahmed
- Iizawa Hiromi
- Iqbal Ahmar
- Iqbal Amar
- Isolauri Erika
- Isolauri Erika
- Jin Hyun Jung
- Kajiwara Chifu
- Kaljonen Anne
- Kamijo Koji
- Kandhare Amit
- Karmakar Bijoya
- Kivity Shmuel
- Kobayashi Miyabi
- Koch Pierluigi
- Kong Amanda M.
- Kopelentová Eliška
- Kulalert Prapasri
- Labella Marina
- Lapshyn Volodymyr
- Lazarescu Marilena
- Lee Soo-Keol
- Limb Susan L.
- Lluch Magdalena
- Lundelin Krisa
- Luskin Allan T.
- Malamisura Monica
- Malet Alfonso
- Martelli Alberto G.
- Martí Guadaño Enrique
- Martí José Natalia
- Martínez Patricia
- Marusciac Laura
- Marusciac Laura
- Marzano Valeria
- Mazzina Oscar
- Mazzina Oscar
- Mazzina Oscar
- Mazzina Oscar
- Mennini Maurizio
- Mennini Maurizio
- Mennini Maurizio
- Mennini Maurizio
- Mitsunaga Kanako
- Mukherjee Anwesha
- Nam Young-Hee
- Napolitano Tania
- Navarrete Elsy
- Nermes Merja
- Nishigata Kotarou
- Novobílská Jana
- Oana Yu-ta
- Okhotnikova Olena
- Okishima Naoko
- Ortiz Benjamin
- Paknis Brandee
- Panaitescu Bunu Carmen
- Panitescu Bunu Carmen
- Paralescu Sorin
- Paralescu Sorin
- Pathumanond Jayanton
- Pau Casanovas Pol
- Pecora Valentina
- Pecora Valeria
- Perez Aviles Herberth J.
- Peñalver Marcos
- Pienar Corina
- Pincock Tobias
- Pineda Fernando
- Pineda Fernando
- Pineda Fernando
- Pitchon dos Reis Raquel
- Pitt Tracy
- Plaza Ana María
- Pop Liviu L.
- Pozo F. Cesar
- Prados Manuel
- Putignani Lorenza
- Rea Francesca
- Reddel Silvia
- Reis Adriana
- Ribeiro Henrique
- Riccardi Carla
- Riccardi Carla
- Riccardi Carla
- Rodriguez Diego
- Rodriguez Diego
- Rosen Karin
- Rottem Menachem
- Ríos Luis Alberto
- Salminen Seppo
- Santamaria Francesca
- Sato Hironori
- Sato Sakura
- Sato Sakura
- SenGupta Koyel
- Sharikadze Olena
- Shimodaira Moe
- Shimojo Naoki
- Shimojo Naoki
- Sritipsukho Paskorn
- Sugizaki Chizuko
- Suzuki Tomoka
- Szefler Stanley
- Sánchez Borges Mario
- Takai Mizuki
- Tamas Paul
- Tamas Paul
- Tambucci Renato
- Teague W. Gerald
- Tomiita Minako
- Traina Giovanni
- Trzaskoma Benjamin
- Trzaskoma Benjamin L.
- Tǎmaş Liviu
- Umanets Mykola
- Umanets Tetiana
- Umanets Tetiana
- Universitat Autònoma de Barcelona
- Valentini Diletta
- Valluzzi Rocco Luigi
- Valluzzi Rocco Luigi
- Valluzzi Rocco Luigi
- Vega Arantza
- Velasco Berenice
- Vernocchi Pamela
- Vieira Hernandez Alberto
- Víšek Petr
- Wagelie-Steffen Amy
- Weinbrand-Goichberg Jenny
- Yamaide Akiko
- Yamaide Fumiya
- Yanagida Noriyuki
- Yanagida Noriyuki
- Yoda Ryou
- Yuriev Sergey
- Zeiger Robert S.
- Íbero Marcel
- Šetinová Ivana
- Štádler Jakub
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
Evolution over Time of Ventilatory Management and Outcome of Patients with Neurologic Disease∗
- Author
- Abderrahim Azzouzi
- Abroug F.
- Achille Kouatchet
- Achim Lunkeit
- Adam Mikstacki
- Aguilera García
- Ahmed Sbihi
- Ai-Chin Cheng
- Ainhoa Rosselló
- Alain Mercat
- Alan Javier Zazu
- Alberto Belenguer
- Alberto Deicas
- Alberto Marino
- Alberto Soler
- Alejandro Algora
- Alejandro Arroliga
- Alejandro de la Serna
- Alejandro Gómez
- Alejandro Raimondi
- Alejandro Risso
- Alfonso Moreno
- Alfonso Muñoz
- Alfredo Padrón
- Alfredo Vasquez-Sandoval
- Ali Aydım Altunkan
- Ali Zeggwagh A.
- Aline Camile Yehia
- Alistair Nichol
- Allan Walkey
- Allison Bone
- Aloísio Marques do Nascimento
- Alvaro van Bommel
- Amalia Martínez de la Gandara
- Amber Monson
- Ambrogio Sansone
- Amee Patrawalla
- Amin P.
- Amine Ali Zeggwagh
- Amparo Ferrandiz
- Amy Waters
- Ana Carolina Caballero
- Ana Esther Trujillo
- Ana Villagrá
- Anders Aneman
- Andrea Gimenez
- Andrea Matte
- Andrea Neville Cracchiolo
- Andreas Schwartz
- Andreas Viehöfer
- Andrei Piontek
- Andrew Bersten
- Andrew Davies
- Andrew Davies
- Andrew Davies
- Andrew Steel
- Andrey Yaroshetskiy
- Anette Mortensen
- Anitha Shenoy
- Ankur Devendra Bhavsar
- Annunziata Mattei
- Anthony Saleh
- Antonina Pigna
- Antonino Giarratano
- Antonio Anzueto
- Antonio Braschi
- Antonio Corcione
- Antonio García-Jiménez
- Antonio Maestre
- Antonio Pesenti
- Antonio Raso
- Antonio Reyes
- Antonio Villa Delgado
- Antonio Viñuales
- Anzueto A.
- Arianna Boggero
- Ariel Chena
- Armando Pedulla'
- Arnaud W Thille
- Ashley Ellis
- Ashley Ellis
- Asisclo J Villagómez Ortiz
- Auke Reidinga
- Ayed Samia
- Barbara Tamowicz
- Barrios D.
- Bas M Kors
- Begoña Balerdi
- Benoit Veber
- Bernabé Álvarez
- Bersten A.
- Bert Beishuizen
- Besbes Mohamed
- Bilge Çetin
- Bin Du
- Bin Du
- Bin Yu
- Bing Sun
- Birgitte Viebaek
- Bladimir Alejandro Gil
- Bo Broberg
- Bo Wang
- Boris Villamagua
- Brian Sherman
- Bruno Bonaccorsi Fernandino
- Bruno do Valle Pinheiro
- Bryan Beatty
- C Canevet
- Cakar N.
- Cameron Knott
- Camilo Pizarro
- Carlo Alberto Acosta
- Carlos Alberto Studart Gomes
- Carlos André Correia Casado
- Carlos Andrés Díaz
- Carlos Gallego
- Carlos Marian Crespo
- Carlos Robles-Arias
- Carmelo Dueñas
- Carmen Campos
- Carolina Gímenez-Esparza
- Carolina Lorencio
- Cartan Costello
- Catherine Simmonds
- Cayce Strength
- Cayetano Galetti
- Cecilia Carbayo
- Cecilia Hermosa
- Cecilia Pereyra
- Cesar Enciso
- Cezar Mihailescu
- Chabu Coronado
- Chafrina Marie Olay
- Chang Liu
- Chantal Hogan
- Charki Haimeur
- Chau Chin Man
- Chen Chin-Ming
- Chengmin Yu
- Cheromi Sittambalam
- Cheryl Cuzner
- Cheryl Ethier
- Chiara Verga
- Christian Frenkel
- Christian Putensen
- Christopher MacIsaac
- Christopher Spradley
- Chuanyun Qian
- Claire Cattigan
- Claire Reynolds
- Clara Laplaza Eva Regidor
- Clara Pacheco
- Claudia Diaz
- Claudia Olvera-Guzman
- Craig A Piquette
- Craig Cernosek
- Crissie De Spirito
- Crissie Despirito
- Cristian Casabella
- Cristian Cevallos
- Cristina Orlandi
- Cristina Santos
- César Antonio Maquilon
- César Aragón
- César Cruz Lozano
- César Pérez-Calvo
- Damian Violi
- Dana K Soetaert
- Daniel Duarte
- Daniel Fontaneda
- Daniel Vargas
- Daniel Weiss
- David Freire
- David Milliss
- Davide Chiumello
- Daxing Yu
- Debiao Song
- Deborah Barge
- Deborah Cook
- Deepak Govil
- Del-Sorbo L.
- Denice Wells
- Dennis Bergmans
- Dhruva Chaudhry
- Di Russo
- Diane Mackle
- Dianne Hill
- Dianne Stephens
- Dietrich Henzler
- Dimitros Matamis
- Dimple Tejwani
- Dinalva Aparecida Gomes
- Do Danh Quynh
- Dolores Vila
- Dongpo Jiang
- Dorothée Carpentier
- Du B.
- Edgard Luna
- Edgardo E Tabhan
- Edgardo Nuñez
- Edoardo De Robertis
- Eduard Bootsma
- Eduardo Almeida
- Eduardo Fonseca Sad
- Edward Nicolayenko
- Eileen Gilder
- Elena Gallego
- Elena Parreño
- Eleni Antoniadou
- Elias Caragna
- Elisa Estenssoro
- Elisha Fulton
- Elisha Matheson
- Ellen Kinkel
- Emily Stern
- Enrique Maraví
- Enrique Piacentini
- Erika Mannelli
- Erin Braden
- Erna Alberts
- Erwin J Oei
- Esteban A
- Eugenio Palazón
- Eva Benveniste
- Eva Manteiga
- Fabien Grelon
- Fabien Soulis
- Fabricio Picoita
- Fachun Zhou
- Falk Hildebrandt
- Fang Xu
- Farhad N Kapadia
- Fausto Fialho Moura
- Federica Antonicelli
- Federica Tallarini
- Federico Gordo
- Fekri Abroug
- Feng Li
- Fernando Antônio Botoni
- Fernando Fernández
- Fernando Lambert
- Fernando Lipovestky
- Fernando Pérez
- Fernando Ríos
- Fernando Saldarini
- Fernando Sánchez
- Fernando Villarejo
- Fernando Villarejo
- Filomena Faria
- Forbes McGain
- Francesca Frigieri
- Francesco Idone
- Francesco Mojoli
- Francisco Criado
- Francisco Guerrero
- Francisco Lucena
- Francisco Manzano
- Francisco Molina
- Francisco Ortuño
- Frank Torres
- Franklin Villegas
- François Collet
- Freddy Sandy
- Freddy Sánchez
- Frederico Costa Val Barros
- Frederico Rodrigues Anselmo
- Frutos-Vivar F.
- Frédéric Bellec
- Félix Lacoma
- Gabriel D Empaire
- Gaetano Perchiazzi
- Gang Li
- Gary Kinasewitz
- Gary Kinasewitz
- Gastón Pittini
- Gaëtan Bedunaeu
- Gee Young Suh
- Gemma Rialp
- Geneva Tatem
- Geng Zhang
- Genis Carrasco
- George Liziamma
- George Lukas
- Gerardo Filippa
- Gilda Diaz-Fuentes
- Gina Quinde
- Giorgia Citterio
- Giorgio Tulli
- Gonzalez M.
- Gonzalo Javier Ríos
- Graciela Elizabeth
- Graciela Franca
- Graeme Duke
- Gregory A Schmidt
- Guillaume Marcotte
- Guillermo Chiappero
- Guillermo Cueto Robledo
- Guillermo Falconí
- Guillermo Muñiz
- Guillermo Ortiz
- Gustavo Badariotti
- Gustavo Jannello
- Gustavo Morales Muñoz
- Gustavo Paredes
- Géraldine Dessertaine
- Haibo Qiu
- Hannah Mathers
- Hans-Henrik Bülow
- Harald Fritz
- Harry P P M Gelissen
- Heinrich Paulus
- Heinz Kerger
- Helen Rodgers
- Helen Wong
- Heloisa Castro
- Henry Caballero
- Hergen Buscher
- Hernan Nunia
- Hernán Nuñez
- Hong Pu
- Hongyang Xu
- Hongyuan Lin
- Howard Connor
- Hugo Capponcelli
- Hugo Urbano
- Hye Sook Choi
- Ian Carrasco
- Ian Moore
- Ian Seppelt
- Ilaria Curro'
- Ilaria Maria Mastromauro
- Imed Chouchene
- Imogen Mitchell
- Ingrid van den Hul
- Ingrid Von der Osten
- Inmaculada Vallverdú
- Irene Aragão
- Irene Dot
- Irene Watpool
- Islem Ouanes
- Ismail Kati
- Itziar Mintegui
- Ivano Aprile
- Jacinto Baena
- Jackeline Coello
- Jan Dittmann
- Jan Friedrich
- Jan Mehrtens
- Jane Thomas
- Janine Dias Alves
- Jasmin Board
- Jasmin Board
- Jasmin Board
- Jason Fletcher
- Javier Blanco
- Javier Castañeda
- Javier Cebrián
- Javier Díaz Domínguez
- Javier García-Alonso
- Javier González-Robledo
- Javier Horacio Álvarez
- Javier Hurtado
- Javier Ladape Martinez
- Javier Ruiz
- Je Hyeong Kim
- Jean-Christophe M Richard
- Jeff Presneill
- Jeffrey Singh
- Jennifer Germain
- Jennifer Goodson
- Jennifer Holmes
- Jennifer Twombley
- Jenny Dennett
- Jens Brushoj
- Jens Buettner
- Jesús Sánchez
- Jesús Sánchez-Ruiz
- Jian Huang
- Jianbiao Meng
- Jianguo Li
- Jianhong Fu
- Jianying Guo
- Jiaqiong Li
- Jibaja M.
- Jin Hwa Lee
- Jin Young An
- Jinghua Wang
- Jiuzhi Zhang
- Joachim Hartung
- Joan Maria Raurich
- Joana Silvestre
- Joanne Sutton
- Jodi Brown
- Johannes Busch
- John Durning
- John Myburgh
- John Oropell
- John Santamaria
- Jorge Arroyo
- Jorge Gerez
- Jorge Vidal Hernández
- Jorgelina Guyon
- Jose Angel Baltazar Torres
- Josep Maria Sirvent
- José Carlos Versiani
- José Claudio Leo
- José Elizalde
- José Francisco López Baca
- José J Blanco
- José Luis Scapellato
- José Manuel Serrano
- José María Gutiérrez
- José María Montón
- José María Nicolás
- José María Quiroga
- José Miguel Guerrero
- José Salinas
- José Salvador Martínez Cano
- Joyce Okahashi
- Juan Carlos
- Juan Carlos Maurelia
- Juan David Uribe
- Juan Diego Jiménez
- Juan Domingo Fernández
- Juan Guerra
- Juan Pablo Sedano
- Juan Ramón Cortés
- Juanxian Gu
- Judi Tai
- Judith Sagardía
- Julia López-Díaz
- Julian Strati
- Julie Smith
- Julio Osorio
- Julio Pontet
- Julián Hernández
- Jun Jin
- Jörg Haberkorn
- Jörn Schlechtweg
- Karina Bonasegla
- Katherine Davidson
- Kathleen Lilli
- Katty Trelles
- Kelly Choy
- Kerry Canady
- Ki-Suck Jung
- Kim Heus
- Konstantinos Raymondos
- Kwan Ming Chit
- Kyung Chan Kim
- Larry Welder
- Laura Jones
- Laura Sayagues
- Laura Wilson
- Laura Álvarez-Montero
- Lauralyn McIntryre
- Laurent Brochard
- Leanne Boehm
- Lei Chen
- Leila Eckholt
- Leonardo Pazmiño
- Leonie Weisbrodt
- Leticia Rapetti
- Liang Pan
- Lidón Mateu
- Liliana Caipe
- Lisa Julien
- Lisandro Betttini
- Loredana Pitagora
- Lori-Ann Kozikowski
- Lucas Vallejo
- Lucia Capilla
- Luis Fernando Castro Castro
- Luis Gonzalez Mosquera
- Luis González Zambrano
- Luis Marina
- Luis Pablo Cardonnet
- Luis Soto-Germani
- Luis Soto-Román
- Luis Williams
- Lutz Pfeiffer
- Lynette Newby
- M Eugenia
- Madhav Gudi
- Madison Dennis
- Maggiore S. M.
- Manoj K Saxena
- Manuel Jibaja
- Manuel Valledor
- Maoqin Li
- Mar Gobernado
- Marc Fabra
- Marc Lipkus
- Marcela Canola-Mazo
- Marcela Granados
- Marcelo Alcântara Holanda
- Marcelo Choque
- Marcelo Ochoa
- Marcelo Palavecino
- Marco Adversi
- Marco Antônio Ribeiro Leão
- Marco Antônio Soares Reis
- Marco Bezzi
- Marco Escobar
- Marco Gonzalez
- Marco González
- Marco Montes De Oca
- Marcos Delgado
- Marcos Juan Zec
- Marcus Ruecker
- Maria Aparecida Braga
- Maria Del Mar Torres-Perez
- Maria Giannakou
- Maria Wussow
- Mariana Monllau
- Marianna Esposito
- Marin M. D. C.
- Marina Busico
- Mario Acosta
- Mario Alonso Treviño Salinas
- Mario Cancela
- Mario Gómez
- Mario Villabon
- Marisol Rodríguez-Goñi
- Mark Bailey
- Mark Tidswell
- Markus Schappacher
- Marta Beron
- Marta Ferrari
- Marta Ugalde
- Martin Deheza
- Martín Lugaro
- Mary La Pine
- María Belén Yapur
- María Del Carmen de la Torre
- María Elena Pérez-Losada
- María Eugenia González
- María Fernanda García
- María Garitacelaya
- María Isabel Ruiz
- María José Tolón
- María Luisa Navarrete
- María Victoria de la Torre
- María Ángeles Alonso
- María Ángeles Pena
- Matamis D.
- Matthew Kirchner
- Matty Koopmans
- Matías Brizuela
- Mauricio Vinzio
- Maurizio Bottiroli
- Maurizio Raineri Santi
- Maurício Meireles Góes
- Maximillian Ragaller
- Mayur Patel
- Medhat Soliman
- Mehar-Un-Nisa Raja
- Mian Chen
- Michael A Kuiper
- Michael Miletin
- Michael Quintel
- Michela Bombino
- Michele Iannuzzi
- Miguel Fernández-Vivas
- Miguel Lazcano
- Miguel León
- Miguel Llano
- Miguel Ángel González-Gallego
- Mijail Játiva
- Mikhail Kirov
- Mikkel Præst
- Minka Springham
- Miquel Ferrer
- Mirko Belliato
- Mohamed A Saad
- Mohammed Al-Jagbeer
- Monica Rocco
- Monika Holler
- Moo Suk Park
- Mounir Bouaziz
- Mourad Amor
- Muriel A.
- Myriam Montalvo
- Myung-Goo Lee
- Nagarajan Ramakrishnan
- Nahit Cakar
- Neill Adhikari
- Nelson Barros
- Nelson Fonseca
- Nelson Medina
- Nghuyen Ba Tuan
- Nguyen Huu Hoang
- Niall Ferguson
- Nicolas Nin
- Nicole Marinoff
- Nicolás Zamboschi
- Nieves Franco
- Nils Marquardt
- Nin N.
- Norberto Tiribelli
- Norberto Tiribelli
- Norma Beatriz Márquez
- Nuria Alonso
- Oliver Franke
- Olivia Dulfo
- Orla Smith
- Oscar Cluzet
- P Kruska
- P Samaddar
- Pablo Desmery
- Pablo Gómez
- Pang Wing Yan
- Paolo Navalesi
- Pascal Beuret
- Pascual Valdez
- Patricia Albert
- Patricia Jimeno
- Patricia Leung
- Patricia Vogl
- Paul Goldrick
- Paul J Dennesen
- Paul Young
- Paulo Marcal
- Pedro Alzugaray
- Pedro Galdos
- Pedro Jesús Domínguez
- Pedro Rosa
- Pelosi P.
- Penuelas O.
- Pertsas Evangelos
- Peter van der Voort
- Pham Thi Van Anh
- Phil Alkana
- Philippe Berger
- Pierre-Gildas Guitard
- Prachee Sathe
- Pravin Amin
- Priya Nair
- Qing Song
- Qingyuan Zhan
- Qunmei Yao
- Rachael Parke
- Rachel Whyte
- Rafael Blancas
- Rafael Morales
- Rahul Nanchal
- Raju Pusapati
- Ramiro Puetate
- Raquel Manzanedo
- Raquel Montoiro
- Raquel Yano
- Raymondos K.
- Raúl de Pablo
- Raúl González
- Raúl Lombardi
- Remzi Iscimen
- Ricardo Buitrago
- Ricardo Martinez Zubieta
- Ricardo Matos
- Rick McAllister
- Rios F.
- Robba C.
- Robert Fowler
- Robyn Klages
- Rodrigo E Gómez-Paz
- Roger Lamoglie
- Rogério de Castro Pereira
- Roland Schneider
- Rolf Dembinski
- Rolf Rossaint
- Rollin Roldán Mori
- Romano Tetamo
- Román Garrido
- Ronald Pairumani
- Ronnie Mantilla
- Rosa Luz López Martínez
- Rosa Sebastián
- Rosa Álvaro
- Rosalba Tufano
- Rosanna Del Giudice
- Rosanna Vaschetto
- Rosario Urbino
- Rovílson Lara
- Rovílson Lara
- Rubens Altair Amaral de Pádua
- Rubén Camargo
- Rui Moreno
- Rupesh Vakil
- Ryan Albert
- Sabriye Guvenc
- Salem Ould Zein
- Salvatore Maurizio Maggiore
- Samer Haj-Bakri
- Samir Abdelhadi
- Samir Sahu
- Samir Vermani
- Sando Chavarria
- Sangeeta Mehta
- Sanjay Dhanuka
- Santiago Ilutovich
- Sara Cabañes
- Schimdt Alejandra
- Sebastian Circo
- Sebastián E Mare
- Serena Azzari
- Serge Heines
- Sergio Cáceres
- Sergio Lasdica
- Seton Henderson
- Shawna Reddie
- Sheila Nainan Myatra
- Shelby Sutton
- Sheree Gare
- Shirley Nelson
- Shouhong Wang
- Silke Frenzel
- Silvia Mareque
- Silvina Borello
- Silvio A Ñamendys-Silva
- Simon J G Hockley
- Simona Beniczky
- Sindhaghatta Venkatram
- Sine Wichman
- Smyth Smith
- Soares M. A.
- Sofía García
- Soraya Puertas
- Srinivas Samavedam
- Stambouli Neji
- Steffen Appel
- Steffen Weber-Carstens
- Stephanie Lubchansky
- Stephen Lapinsky
- Steven Y Chang
- Stevens Salva
- Subhash Kumar Todi
- Sujoy Mukherjee
- Susan Gillen
- Susana Alves Ferreira
- Susana Moradillo
- Susana Temprano
- Susanne Andi Iversen
- Sutherasan Y.
- Sutrisno Gunawan
- Sylvia den Boer
- Tania Caf
- Tarek Dendane
- Tayfun Adanir
- Tejerina E. E.
- Teresa Mut
- Teresa Sánchez de Dios
- Thille A. W.
- Thomas Bein
- Thomas Lipp
- Thomas Moellhoff
- Thomas Steinke
- Thoralf Kerner
- Tiehe Qin
- Tim Coles
- Tim Houlihan
- Timothy D Girard
- Tom Cowlam
- Tony Sutherland
- Tony Williams
- Travis Parry
- Troy Browne
- Tumbass Volker
- Uli Strauch
- Umesh G
- Unase Büyükkoçak
- V J Cardenas Jr
- Valentín Parra
- Valerio Mangani
- Valery Subbotin
- Valle Pinheiro B.
- Valéria de Carvalho Magela
- Vanesa Ramírez
- Vicente Arraez
- Victoria Goñi
- Vincent John Scott
- Vito Marco Ranieri
- Vivek Joshi
- Wajdi Maazouzi
- Walter Brandt
- Walter Seyde
- Wanxia Li
- Wei He
- Wei Yu
- Wei Zhang
- Weihai Yao
- William Rodriguez-Cintron
- Winfried Schubert
- Wolfgang Baier
- Won-Yeon Lee
- Xi Zhu
- Xianyao Wan
- Xiaobo Huang
- Xue Wang
- Yalin Liu
- Yan Kang
- Yangong Chao
- Yaseen Arabi
- Yi Li
- Yi Yang
- Yogeet Kaur
- Yongjie Yin
- Young Suh G.
- Younsuck Koh
- Yu Bai
- Yuan Xu
- Yuhong Guo
- Yun Seong Kim
- Yunxuan Yue
- Zafer Dogan
- Zalatiel Maycotte Luna
- Zaza Cohen
- Zhengxuan Lv
- Zhenjie Hu
- Zhenyang He
- Zhicheng Zhang
- Zhihua Hu
- Zhixiang Li
- Zoltan Szentkereszty
- Zoraida Parra
- Zsolt Molnar
- Ángela Alonso
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/11/2021
- Field of study
OBJECTIVES: To describe the changes in ventilator management over time in patients with neurologic disease at ICU admission and to estimate factors associated with 28-day hospital mortality. DESIGN: Secondary analysis of three prospective, observational, multicenter studies. SETTING: Cohort studies conducted in 2004, 2010, and 2016. PATIENTS: Adult patients who received mechanical ventilation for more than 12 hours. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Among the 20,929 patients enrolled, we included 4,152 (20%) mechanically ventilated patients due to different neurologic diseases. Hemorrhagic stroke and brain trauma were the most common pathologies associated with the need for mechanical ventilation. Although volume-cycled ventilation remained the preferred ventilation mode, there was a significant (p < 0.001) increment in the use of pressure support ventilation. The proportion of patients receiving a protective lung ventilation strategy was increased over time: 47% in 2004, 63% in 2010, and 65% in 2016 (p < 0.001), as well as the duration of protective ventilation strategies: 406 days per 1,000 mechanical ventilation days in 2004, 523 days per 1,000 mechanical ventilation days in 2010, and 585 days per 1,000 mechanical ventilation days in 2016 (p < 0.001). There were no differences in the length of stay in the ICU, mortality in the ICU, and mortality in hospital from 2004 to 2016. Independent risk factors for 28-day mortality were age greater than 75 years, Simplified Acute Physiology Score II greater than 50, the occurrence of organ dysfunction within first 48 hours after brain injury, and specific neurologic diseases such as hemorrhagic stroke, ischemic stroke, and brain trauma. CONCLUSIONS: More lung-protective ventilatory strategies have been implemented over years in neurologic patients with no effect on pulmonary complications or on survival. We found several prognostic factors on mortality such as advanced age, the severity of the disease, organ dysfunctions, and the etiology of neurologic disease
Recommended from our members
7th Drug hypersensitivity meeting: part two
- Author
- A. Puangpetch
- Abdelbaset A. Elzagallaai
- Abdulaziz Alzahrani
- Abha Chopra
- Adriana Ariza
- Adriana M. Mendoza Parra
- Alberto Lafuente
- Alberto Manuel Borobia
- Alec James Redwood
- Alec Redwood
- Alejandra Monroy Arreola
- Alessandra Vultaggio
- Alex Lacerda
- Alex Upton
- Ali Kokuludag
- Alicia Beeghly-Fadiel
- Alicia Martinez Romero
- Alla Nakonechna
- Amalia Bernad
- Amalia Bernad Alonso
- Amel Chaabane
- Amelia García Luque
- Amélia Spínola-Santos
- An Goossens
- Ana Alfirevic
- Ana Castro Neves
- Ana Fiandor
- Ana M. Montoro De Francisco
- Ana Maria Martins
- Ana María Fiandor
- Ana María Fiandor Roman
- Ana Molina
- Ana Moreira
- Ana Paula Pires
- Ana Rodolfo
- Ana Todo Bom
- Anabela Lopes
- Anca Chiriac
- Andrea Matucci
- Andrew Gibson
- Andrew Sullivan
- Angel Esteban Rodriguez
- Angela Martin-Serrano
- Angella M. Burgos Pimentel
- Annick Barbaud
- Anthony Purcell
- Antonia Thinnes
- Antonino Romano
- Antonio Alvarez
- Antonio E. Guzmán
- Aranzazu Jimenez Blanco
- Aranzazu Jimenez Blanco
- Arturo Ruiz
- Arun Tailor
- Asli Gelincik
- Astrid P. Uyttebroek
- Aurore Rozières
- Awatif M. Abuzgaia
- Axel Patrice Villani
- Aylin Türel Ermertcan
- Ayse Aktas
- Aytül Zerrin Sin
- B. Kevin Park
- Bahauddin Colakoglu
- Bautista De La Cruz Hoyos
- Beatriz Pola
- Beatriz Pola Bibián
- Benoît Bensaïd
- Bernard Maillere
- Bárbara Kong Cardoso
- Carla Torán Barona
- Carlos Flores
- Carmelita Ribeiro
- Carmen D’Amelio
- Carmen D’Amelio Garófalo
- Carolann Mcguire
- Carolina Aranda
- Carolina Perales Chorda
- Carolina Perales Chordá
- Caroline J. Harrison
- Carsten Bindslev-Jensen
- Catherine Betts
- Cathy Nhim
- Ceyda Tunakan Dalgiç
- Charlotte G. Mortz
- Chie Sotozono
- Chien-Yio Lin
- Chih-Hsun Yang
- Chonlaphat Sukasem
- Chris H. Bridts
- Christian Möbs
- Christina Cheng
- Christine Breynaert
- Chung-Yee Rosaline Hui
- Clémence Delahaye
- Cosmin Boteanu
- Cristobalina Mayorga
- Cíntia Rito Cruz
- Danica Juricic Nahal
- Daniel Collado
- Daniel Peckham
- Daniela Malheiro
- Dean J. Naisbitt
- Delphine Joseph
- Derya Unal
- Diana Kury Valle
- Diana Pérez-Alzate
- Diana Silva
- Didier G. Ebo
- Dirceu Solé
- Dolores Hernández Fernández De Rojas
- Dolores Pérez-Sala
- Ekaterini Goudouris
- Elena García-Martín
- Elena Ramirez
- Elisa Boni
- Elizabeth Mckinnon
- Elizabeth Phillips
- Elza Tomaz
- Emily Woolnough
- Emine Nihal Mete Gökmen
- Emre Ali Acar
- Emília Faria
- Enrico Maggi
- Erna Van Hoeyveld
- Esin Çatin-Aktas
- Esther Barrionuevo
- Eunice Dias De Castro
- Eunice Dias-Castro
- Ezequiel Perez-Inestrosa
- Ezequiel Pérez-Inestrosa
- Fabrícia Carolino
- Fatma Düsünür Günsen
- Fatma Sen
- Fatma Ömür Ardeniz
- Fernando Pineda
- Fernando Pineda De La Losa
- Fiazia Yaseen
- Filipe Benito-Garcia
- Filipe Inácio
- Floriane Albert
- Francesca Nencini
- Francisca Arribas
- Francisca Arribas Poves
- Francisca Palomares
- Francisco J. Sánchez-Gómez
- Francisco José De Abajo
- Francisco Najera
- Gabriel Gastaminza
- Gabriel Gastaminza Lasarte
- Gabriela Canto
- Gador Bogas
- Galina Balakirski
- Gemma Vilà-Nadal
- Gunnur Deniz
- Gökten Bulut
- Haifa Ben Romdhane
- Hamza Ugur Bozbey
- Hannah Dörnbach
- Hans F. Merk
- Heidi Fettke
- Helena Rupnik
- Heung-Woo Park
- Hidefumi Wada
- Hideo Hashizume
- Hiroaki Azukizawa
- Hiromi Sawai
- Hoi Tong
- Hwa Young Lee
- Hye-Ryun Kang
- I. Olazabal
- Ichiro Katayama
- Ines Camelo Nunes
- Inmaculada Andreu
- Inmaculada Doña
- Inês Mota
- Irene Carrasco García
- Isabel Carrapatoso
- Iva Kraljickovic
- Ivana Cegec
- Iveta Simic
- J. Dionicio
- J. P. Moreira Da Silva
- Jaechun Jason Lee
- Jaime Tubella Lopez
- James Perkins
- James Richard Perkins
- Janet Maryanski
- Jason Trubiano
- Jaume Martí Garrido
- Javier Dionicio Elera
- Javier Dominguez Ortega
- Javier Domínguez
- Javier Fernandez Sanchez
- Jay Chol Choi
- Jean-François Nicolas
- Jean-Louis Guéant
- Jeffrey Lai
- Jenny Flabbee
- Jens Malte Baron
- Jer-Yuarn Wu
- Jesus Agustin Badillo Corona
- Jettanong Klaewsongkram
- Joana Belo
- Joana Cosme
- Joana Pita
- Johanna Visse
- John Farrel
- John Farrell
- Jorge Frances Ferre
- Jorge Núñez
- Jose Julio Laguna
- Jose Julio Laguna Martinez
- Jose Luis Castañer
- Jose Luis Castrejon Flores
- Josefina R. Cernadas
- José Antonio Cornejo-García
- José Augusto García-Agúndez
- José Francisco Da Silva Franco
- João Marques
- Juan M. González-Morena
- Judith Dominguez Cherit
- Julie Waton
- Kaija Stautins
- Kaija Strautins
- Karim Aouam
- Katherine Konvinse
- Kathrin Scherer Hofmeier
- Katie White
- Katushi Tokunaga
- Kayoko Oda
- Kenichi Kato
- Khetam Alhilali
- Kok Loong Ue
- Kristina Williams
- Krzysztof Rutkowski
- Ksenija Makar Ausperger
- Kulprapat Pairayayutakul
- Kyung-Up Min
- Leandra Queiroz
- Lee Faulkner
- Leonor Carneiro Leão
- Liesbeth Gilissen
- Lindsey Chow
- Line K. Tannert
- Lucia Fili
- Luis Amaral
- Luis Felipe Ensina
- Luis Mario Tubella Marti
- Magna Correia
- Manuel Pereira-Barbosa
- Marc Pallardy
- Marc Vocanson
- Marcia Ribeiro
- Maria Aranzazu Jimenez Blanco
- Maria Del Carmen Plaza-Serón
- Maria Dolores Ruiz
- Maria Isabel Montañez
- Maria Isabel Sanchez
- Maria Jose Goikoetxea
- Maria Jose Torres
- Maria José Torres
- Maria Rosario Cabañas Moreno
- Maria-João Paes
- Mariana Castells
- Marie Eliane Azoury
- Marina Lluncor
- Marina Lluncor Salazar
- Marina Mauro
- Marina Russello
- Marina Voronova
- Marta Chambel
- Marta Del Pozo
- Marta E. Polak
- Marta Ferrer
- Marta Ferrer Puga
- Martin Leverkus
- María Auxiliadora Guerrero
- María Gabriela Canto
- María Isabel Montañez
- María J Torres
- María J. Torres
- María José Goikoetxea Lapresa
- María José Torres
- María Luisa Galindo
- María Salas
- Matea Radacic Aumiler
- Mathilde Tardieu
- Mayumi Ueta
- Megumi Satoh
- Michael J. Rieder
- Michael R. Ardern-Jones
- Michele Rauber
- Michiko Aihara
- Miguel Blanca
- Miguel Díaz Palacios
- Miguel Gonzalez Muñoz
- Mihaela Zidarn
- Min-Suk Yang
- Mira Silar
- Mohammad Alhaidari
- Monday O. Ogese
- Monday Ogese
- Muge Olgac
- Munir Pirmohamed
- Mário Morais-Almeida
- N. Koomdee
- Naceur A. Boughattas
- Nadia Ben Fredj
- Najah Ben Fadhel
- Nancy Claude
- Natalia Blanca-López
- Neil S. French
- Neill Berry
- Nicole Mifsud
- Nicole Pinto
- Noe Valentin Duran Figueroa
- Noemi Molina
- Noémie Scornet
- Nuno Sousa
- Okan Gülbahar
- Olga Vega
- Olga Vega Matute
- Olivia Bauvin
- Osami Kanagawa
- Oswaldo Trelles
- Pablo Andrés Miranda
- Pablo Mesa-Antunez
- Paloma Campo
- Paola Parronchi
- Patompong Satapornpong
- Patricia Illing
- Patrick Kwan
- Patrícia Barreira
- Pau Gomez Cabezas
- Paul M. O’Neill
- Paul Thomson
- Paul Whitaker
- Paula Leiria-Pinto
- Pawinee Rerknimitr
- Pedro Ayuso Parejo
- Pedro Carreiro-Martins
- Per Stahl Skov
- Peter Korosec
- Petra Turcic
- Peyker Temiz
- Raif Coskun
- Rami Bechara
- Ramón López Salgueiro
- Raquel Fuentes Irigoyen
- Raquel Jurado-Escobar
- Rebecca Ho
- Rebecca Pavlos
- Regina Viseu
- Richard Weaver
- Rik Schrijvers
- Rita Aguiar
- Rosa María Guéant-Rodríguez
- Rosa-Anita Rodrigues Fernandes
- Rosalind E. Jenkins
- Rosario Cabañas
- Rosario Gonzalez-Mendiola
- Roselle Catherine Yu Madamba
- Rozalind Jenkins
- Rubén Fernández
- Rute Pereira Dos Reis
- Ružica Jurakic-Toncic
- S. Santon
- Sae-Hoon Kim
- Sally Wood
- Sandra Jerkovic Gulin
- Sang-Heon Cho
- Santiago Quirce
- Santiago Quirce Gancedo
- Sara Correia
- Sara Huygens
- Sara Pratesi
- Semra Demir
- Shay Leary
- Shigeru Kinoshita
- Shuen-Iu Hung
- Silvia Mendez Flores
- Simon Mallal
- Sun-Sin Kim
- Suna Buyuozturk
- Susana Cadinha
- Susana Piedade
- Suzana Ljubojevic
- T. Jantararoungtong
- Tahia D. Fernandez
- Tahia Diana Fernández
- Tahia Fernandez
- Tahía Fernandez
- Tai-Ming Ko
- Taisuke Ito
- Takaaki Hanafusa
- Takatsune Umayahara
- Talía Mª De Vicente Jiménez
- Tatiana Lourenço
- Teodora Lopez Santiago
- Teresa Bellón
- Tetiana Umanets
- Tetsuo Shiohara
- Therdpong Tempark
- Tomohiko Tanegashima
- Tomoya Watanabe
- Toru Usui
- Toshiharu Fujiyama
- Tugba Baysal
- U. Intusoma
- V. Theeramoke
- Verónica Pacheco Coronel
- Vicente Cantó Reig
- Victor Soriano Gomis
- Viktorija Erdeljic Turk
- Violeta Régnier Galvao
- Virginie Mutez
- Vito Sabato
- Vladyslava Barzylovych
- Volodymyr Lapshyn
- W. Tassaneeyakul
- Wei Yann Haw
- Wen-Hung Chung
- Wolfgang Pfützner
- Xiaoli Meng
- Ya-Ching Chang
- Yanni Xue
- Yolanda Vida
- Yoon-Seok Chang
- Yoshiki Tokura
- Yuan-Tsong Chen
- Yukie Yamaguchi
- Yumi Aoyama
- Yurij Antipkin
- Zaid Al-Attar
- Zohra Chadly
- Ángela Martín-Serrano
- Ângela Gaspar
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 18/11/2016
- Field of study
Table of contents Poster walk 11: miscellaneous drug hypersensitivity 2 (P92–P94, P96–P101) P92 16 years of experience with proton pump inhibitors (PPIs) Javier Dionicio Elera, Cosmin Boteanu, Maria Aranzazu Jimenez Blanco, Rosario Gonzalez-Mendiola, Irene Carrasco García, Antonio Alvarez, Jose Julio Laguna Martinez P93 Allergy evaluation of quinolone induced adverse reactions Jaume Martí Garrido, Carla Torán Barona, Carolina Perales Chorda, Ramón López Salgueiro, Miguel Díaz Palacios, Dolores Hernández Fernández De Rojas P94 Bupropion-induced acute urticaria and angioedema, a case report Emre Ali Acar, Ayse Aktas, Aylin Türel Ermertcan, Peyker Temiz P96 Delayed type hypersensitivity and study of cross-reactivity between proton-pump inhibitors Chien-Yio Lin, Chung-Yee Rosaline Hui, Ya-Ching Chang, Chih-Hsun Yang, Wen-Hung Chung P97 Diagnostic work-up in suspected hypersensitivity to proton-pump inhibitors: looking at cross-reactivity Fabrícia Carolino, Diana Silva, Eunice Dias De Castro, Josefina R. Cernadas P98 Management of infusion-related hypersensitivity reactions to enzyme replacement therapy for lysosomal diseases Luis Felipe Ensina, Carolina Aranda, Ines Camelo Nunes, Alex Lacerda, Ana Maria Martins, Ekaterini Goudouris, Marcia Ribeiro, José Francisco Da Silva Franco, Leandra Queiroz, Dirceu Solé P99 Management of insulin allergy with continuous subcutaneous insulin infusion Ceyda Tunakan Dalgiç, Aytül Zerrin Sin, Fatma Düsünür Günsen, Gökten Bulut, Fatma Ömür Ardeniz, Okan Gülbahar, Emine Nihal Mete Gökmen, Ali Kokuludag P100 Off-label use of icatibant for management of serious angioedema associated with angiotensin inhibitors Ana M. Montoro De Francisco, Talía Mª De Vicente Jiménez, Adriana M. Mendoza Parra, Angella M. Burgos Pimentel, Amelia García Luque P101 Thiocolchicoside anaphylaxis: an unusual suspect? Luis Amaral, Fabricia Carolino, Leonor Carneiro Leão, Eunice Castro, Josefina Cernadas Poster walk 12: betalactam hypersensitivity (P102–P111) P102 A curious delayed reading: a case report of a β-lactam allergy in a child Nicole Pinto, Joana Belo, João Marques, Pedro Carreiro-Martins, Paula Leiria-Pinto P103 Betalactam-induced hypersensitivity: a 10-years’ experience Amel Chaabane, Haifa Ben Romdhane, Nadia Ben Fredj, Zohra Chadly, Naceur A. Boughattas, Karim Aouam P104 Cefazolin hypersensitivity: towards optimized diagnosis Astrid P. Uyttebroek, Chris H. Bridts, Antonino Romano, Didier G. Ebo, Vito Sabato P105 Clavulanic acid allergy: two cases report Anabela Lopes, Joana Cosme, Rita Aguiar, Tatiana Lourenço, Maria-João Paes, Amélia Spínola-Santos, Manuel Pereira-Barbosa P106 Diagnosis of betalactam allergy in an allergy department Cíntia Rito Cruz, Rute Pereira Dos Reis, Elza Tomaz, Ana Paula Pires, Filipe Inácio P107 Diagnostic work-up of 410 patients with suspicion of betalactam antibiotic hypersensitivity Filipe Benito-Garcia, Inês Mota, Magna Correia, Ângela Gaspar, Marta Chambel, Susana Piedade, Mário Morais-Almeida P108 Immediate selective hypersensitivity reactions to clavulanic acid Alla Nakonechna, Yurij Antipkin, Tetiana Umanets, Fernando Pineda, Francisca Arribas, Volodymyr Lapshyn P109 Prevalence and incidence of penicillin hypersensitivity reactions in Colombia Pablo Andrés Miranda, Bautista De La Cruz Hoyos P110 Selective sensitization to amoxicilin and clavulanic acid Jose Julio Laguna Martinez, Aranzazu Jimenez Blanco, Javier Dionicio Elera, Cosmin Boteanu, Rosario Gonzalez-Mendiola, Marta Del Pozo P111 Infliximab-specific T cells are detectable also in treated patients who have not developed anti-drug antibodies Alessandra Vultaggio, Francesca Nencini, Sara Pratesi, Andrea Matucci, Enrico Maggi Poster walk 13: biologicals, local anesthetics, others (P112–P118) P112 A case report of allergic immediate systemic reaction to adalimumab and certolizumab Ceyda Tunakan Dalgiç, Fatma Düsünür Günsen, Gökten Bulut, Fatma Ömür Ardeniz, Okan Gülbahar, Emine Nihal Mete Gökmen, Aytül Zerrin Sin, Ali Kokuludag P113 Allergy to local anesthetics: negative predictive value of skin tests Ivana Cegec, Danica Juricic Nahal, Viktorija Erdeljic Turk, Matea Radacic Aumiler, Ksenija Makar Ausperger, Iva Kraljickovic, Iveta Simic P114 Cutaneous adverse reactions of molecular targeted agents: a retrospective analysis in 150 patients in our department Yukie Yamaguchi, Tomoya Watanabe, Megumi Satoh, Tomohiko Tanegashima, Kayoko Oda, Hidefumi Wada, Michiko Aihara P115 Generalized paralysis induced by local lidocaine injection Jaechun Jason Lee, Jay Chol Choi, Hwa Young Lee P116 Hypersensitivity to local anaesthetics: a 10 year review Rosa-Anita Rodrigues Fernandes, Emília Faria, Joana Pita, Nuno Sousa, Carmelita Ribeiro, Isabel Carrapatoso, Ana Todo Bom P117 Local anaesthetics: a rare culprit in hypersensitivity reactions Ana Rodolfo, Eunice Dias-Castro, Josefina Cernadas P118 Stevens–Johnson syndrome in clinical practice: a variant of clinical course Marina Voronova Poster walk 14: RCM (P119–P128) P119 13 cases of severe anaphylactic reactions due to radiocontrast media Jaume Martí Garrido, Ramon Lopez Salgueiro, Diana Kury Valle, Verónica Pacheco Coronel, Carolina Perales Chordá, Dolores Hernandez Fernandez De Rojas P120 Anaphylactic shock after administration of iodinated contrast medium during cardiac catheterization Roselle Catherine Yu Madamba, Marta Ferrer, Maria Jose Goikoetxea, Carmen D’Amelio, Amalia Bernad, Olga Vega, Gabriel Gastaminza P121 Anaphylactic shock and cardiac arrest induced by gadolinium-based contrast agents Beatriz Pola Bibián, Marina Lluncor Salazar, Gemma Vilà Nadal, Ana María Fiandor Roman, Javier Dominguez Ortega, Miguel Gonzalez Muñoz, Santiago Quirce Gancedo, Maria Rosario Cabañas Moreno P122 Anaphylaxis to gadobenate and cross-reactivity to other gadolinium-based contrast agents in two patients Kathrin Scherer Hofmeier P123 Anaphylaxis to glatiramer acetate in a patient with multiple sclerosis Fabrícia Carolino, Vladyslava Barzylovych, Josefina R. Cernadas P124 Delayed hypersensitivity reaction to radiocontrast media Fabrícia Carolino, Diana Silva, Leonor Leão, Josefina R. Cernadas P125 Drug reaction with eosinophilia and systemic symptoms induced by iodixanol Gemma Vilà-Nadal, Beatriz Pola, Marina Lluncor, Ana Fiandor, Teresa Bellón, Javier Domínguez, Santiago Quirce P126 Electronic consultation support system for radiocontrast media hypersensitivity changes clinician’s behavior Min-Suk Yang, Sun-Sin Kim, Sae-Hoon Kim, Hye-Ryun Kang, Heung-Woo Park, Sang-Heon Cho, Kyung-Up Min, Yoon-Seok Chang P127 Hypersensitivity reactions to iodinated contrast media: skin testing and follow-up Danica Juricic Nahal, Ivana Cegec, Viktorija Erdeljic Turk, Iva Kraljickovic, Matea Radacic Aumiler, Ksenija Makar Ausperger, Iveta Simic P128 Would iodine allergy exist? Clémence Delahaye, Jenny Flabbee, Julie Waton, Olivia Bauvin, Annick Barbaud Poster walk 15: MPE/type 4 (P129–P137) P129 Delayed hypersensitivity cutaneous reactions: a case/control study from a tunisian database Karim Aouam, Najah Ben Fadhel, Zohra Chadly, Nadia Ben Fredj, Naceur A. Boughattas, Amel Chaabane P130 Delayed hypersensitivity reactions to cephalosporins: a review of seven cases Joana Cosme, Anabela Lopes, Amélia Spínola-Santos, Manuel Pereira-Barbosa P131 Diclofenac induced allergic contact dermatitis: case series of four patients Sandra Jerkovic Gulin, Anca Chiriac P132 Late-onset maculopapular rash to irbesartan Bárbara Kong Cardoso, Elza Tomaz, Regina Viseu, Filipe Inácio P133 Nonimmediate hypersensitivity reactions to betalactams: a retrospective analysis Ana Moreira, Susana Cadinha, Ana Castro Neves, Patricia Barreira, Daniela Malheiro, J. P. Moreira Da Silva P134 Occupational airborne contact dermatitis to omeprazole Ružica Jurakic-Toncic, Suzana Ljubojevic, Petra Turcic P135 Ornidazole-induced fixed drug eruption confirmed by positive patch test on a residual pigmented lesion Liesbeth Gilissen, Sara Huygens, An Goossens P136 Repeated delayed reaction induced by amoxicillin and amoxicillin clavulanate Inmaculada Andreu, Ramon Lopez-Salgueiro, Alicia Martinez Romero, Pau Gomez Cabezas P137 Systemic photosensitivity from fenofibrate in a patient photo-sensitized to ketoprofen Liesbeth Gilissen, An Goossens Poster walk 16: HLA genetics (P138–P146) P138 A copy number variation in ALOX5 and PTGER1 is associated with nonsteroidal anti-inflammatory drugs induced urticaria and/or angioedema Pedro Ayuso Parejo, Maria Del Carmen Plaza-Serón, Inmaculada Doña, Natalia Blanca López, Carlos Flores, Luisa Galindo, Ana Molina, James Richard Perkins, Jose Antonio Cornejo-García, José Augusto García-Agúndez, Elena García-Martín, Paloma Campo, María Gabriela Canto, Miguel Blanca P139 Association of galectin-3 (LGALS3) single nucleotide polymorphisms with non-steroidal anti-inflammatory drugs-induced urticaria/angioedema José Antonio Cornejo-Garcia, Inmaculada Doña, Rosa María Guéant-Rodríguez, Natalia Blanca-López, María Carmen Plaza-Serón, Raquel Jurado-Escobar, Esther Barrionuevo, María Salas, María Luisa Galindo, Gabriela Canto, Miguel Blanca, Jean-Louis Guéant P140 Detection of T cell responses to ticlopidine using peripheral blood mononuclear cells from HLA-A*33:03+ healthy donors Toru Usui, Arun Tailor, Lee Faulkner, John Farrell, Ana Alfirevic, B. Kevin Park, Dean J. Naisbitt P141 Epistasis approaches to identify novel genes potentially involved in NSAIDs hypersensitivity James Richard Perkins, Jose Antonio Cornejo García, Oswaldo Trelles, Inmaculada Doña, Esther Barrionuevo, María Salas, María Auxiliadora Guerrero, Miguel Blanca, Alex Upton P142 Genetic predisposition of cold medicine related SJS/TEN with severe ocular complications Mayumi Ueta, Hiromi Sawai, Chie Sotozono, Katushi Tokunaga, Shigeru Kinoshita P143 HLA-B*13:01 and dapsone induced hypersensitivity in Thai population Chonlaphat Chonlaphat Sukasem, Patompong Satapornpong, Therdpong Tempark, Pawinee Rerknimitr, Kulprapat Pairayayutakul, Jettanong Klaewsongkram P144 HLA-B*15:02 alleles and lamotrigine-induced cutaneous adverse drug reactions in Thai Chonlaphat Sukasem, N. Koomdee, T. Jantararoungtong, S. Santon, A. Puangpetch, U. Intusoma, W. Tassaneeyakul, V. Theeramoke P145 HLA-B*38:01 and HLA-A*24:02 allele frequencies in Spanish patients with lamotrigine-induced SCARs Teresa Bellón, Elena Ramirez, Alberto Manuel Borobia, Hoi Tong, Jose Luis Castañer, Francisco José De Abajo P146 Overrepresentation of a class II HLA haplotype in severe hypersensitivity type I reactions to carboplatin Violeta Régnier Galvao, Rebecca Pavlos, Elizabeth Mckinnon, Kristina Williams, Alicia Beeghly-Fadiel, Alec Redwood, Elizabeth Phillips, Mariana Castells Poster walk 17: in vivo diagnosis + sIgE (P147–P154) P147 Absence of specific Ig-e against beta-lactams 9 months after an allergic reaction to amoxicillin-clavulanic acid Elisa Boni, Marina Russello, Marina Mauro P148 Drug provocation tests in suspected opioid allergy Kok Loong Ue, Krzysztof Rutkowski P149 Improvement to the specific IgE cut-off in the assess of β-lactamic allergy Victor Soriano Gomis, Jorge Frances Ferre, Angel Esteban Rodriguez, Vicente Cantó Reig, Javier Fernandez Sanchez P150 Initial false negative specific IgE to gelatin in a patient with gelatin-induced anaphylaxis Christine Breynaert, Erna Van Hoeyveld, Rik Schrijvers P151 Inmediate reactions to beta-lactam antibiotics: pattern of skin test response over the time Jose Julio Laguna Martinez, Rosario Gonzalez Mendiola, Javier Dionicio Elera, Cosmin Boteanu, Aranzazu Jimenez Blanco, Marta Del Pozo, Raquel Fuentes Irigoyen P152 New fluorescent dendrimeric antigens for the evaluation of dendritic cell maturation as a test to detect allergy reactions to amoxicillin Daniel Collado, Yolanda Vida, Francisco Najera, Ezequiel Perez-Inestrosa, Pablo Mesa-Antunez, Cristobalina Mayorga, María José Torres, Miguel Blanca P153 Positive skin test or positive specific IgE to penicillin does not predict penicillin allergy Line K. Tannert, Charlotte G. Mortz, Per Stahl Skov, Carsten Bindslev-Jensen P154 Significance of skin testing and in vitro-analysis of neuromuscular blocking agents in diagnosis of perioperative drug hypersensitivity: evaluation of a negative control population Wolfgang Pfützner, Hannah Dörnbach, Johanna Visse, Michele Rauber, Christian Möbs Poster walk 18: in vitro/ex vivo (P155–P158, P160–P164) P155 Diagnostic value of the lymphocyte toxicity assay (LTA) and the in vitro platelet toxicity assay (IPTA) for β-lactam allergy Abdelbaset A. Elzagallaai, Lindsey Chow, Awatif M. Abuzgaia, Michael J. Rieder P156 Enzyme linked immunospot assay used in the diagnosis of severe cutaneous adverse reactions to antimicrobials Alec Redwood, Jason Trubiano, Rebecca Pavlos, Emily Woolnough, Kaija Stautins, Christina Cheng, Elizabeth Phillips P157 Evaluation of in vitro diagnostic methods for identifying the culprit drugs in drug hypersensitivity Kenichi Kato, Hiroaki Azukizawa, Takaaki Hanafusa, Ichiro Katayama P158 Ex-vivo expanded skin-infiltrating T cells from severe drug eruptions are reactive with causative drugs: a possible novel method for determination of causative drugs Toshiharu Fujiyama, Hideo Hashizume, Takatsune Umayahara, Taisuke Ito, Yoshiki Tokura P160 In vitro release of IL-2, IL-5 and IL-13 in diagnosis of patients with delayed-type nickel hypersensitivity Mira Silar, Mihaela Zidarn, Helena Rupnik, Peter Korosec P161 Single cell analysis of drug responsive T cells; identification of candidate drug reactive T cell receptors in abacavir and carbamazepine hypersensitivity Alec James Redwood, Kaija Strautins, Katie White, Abha Chopra, Katherine Konvinse, Shay Leary, Rebecca Pavlos, Simon Mallal, Elizabeth Phillips P162 Specificity and sensitivity of LTT in DRESS: analysis of agreement with the Spanish pharmacovigilance system probability algorithm Rosario Cabañas, Elena Ramirez, Ana María Fiandor, Teresa Bellón P163 The role of interleukin-22 in β-lactam hypersensitivity Andrew Sullivan, Paul Whitaker, Daniel Peckham, B. Kevin Park, Dean J. Naisbitt P164 Vancomycin-specific T cell responses and teicoplanin cross-reactivity Wei Yann Haw, Marta E. Polak, Carolann Mcguire, Michael R. Ardern-Jones Poster walk 19: BAT and biomarkers (P165–P173) P165 A combination of early biomarkers useful for the prediction of severe ADRs Yumi Aoyama, Tetsuo Shiohara P166 Basophil activation test in the diagnostic approach of reactions during general anaesthesia Ana Moreira, Susana Cadinha, Patrícia Barreira, Ana Castro Neves, Daniela Malheiro, Sara Correia, J. P. Moreira Da Silva P167 IL-10 can be related to successful desensitization Asli Gelincik, Semra Demir, Fatma Sen, Hamza Ugur Bozbey, Muge Olgac, Derya Unal, Raif Coskun, Bahauddin Colakoglu, Suna Buyuozturk, Esin Çatin-Aktas, Gunnur Deniz P168 Immediate reactions to proton pump inhibitors: value of basophil activation test Maria Salas, Jose Julio Laguna, Esther Barrionuevo, J. Dionicio, Tahia Fernandez, R. Gonzalez-Mendiola, I. Olazabal, Maria Dolores Ruiz, Miguel Blanca, Cristobalina Mayorga, Maria José Torres P169 Improvement of the elevated tryptase criterion to discriminate IgE from non-IgE mediated allergic reactions Gabriel Gastaminza, Alberto Lafuente, Carmen D’Amelio, Amalia Bernad, Olga Vega, Roselle Catherine Madamba, M. Jose Goikoetxea, Marta Ferrer, Jorge Núñez P170 Low expression of Tim-3 could serve as a biomarker for control and diagnose maculopapular exanthema induced by drugs Tahia Diana Fernández, Inmaculada Doña, Francisca Palomares, Rubén Fernández, Maria Salas, Esther Barrionuevo, Maria Isabel Sanchez, Miguel Blanca, Maria José Torres, Cristobalina Mayorga P171 Role of basophil activation test using two different activation markers for the diagnosis of allergy to fluoroquinolones Esther Barrionuevo, Tahía Fernandez, Arturo Ruiz, Adriana Ariza, Maria Salas, Inmaculada Doña, Ana Molina, Miguel Blanca, Maria Jose Torres, Cristobalina Mayorga P172 The importance of basophil activation test in anaphylaxis due to celecoxib Amalia Bernad Alonso, Carmen D’Amelio Garófalo, Olga Vega Matute, Marta Ferrer Puga, María José Goikoetxea Lapresa, Roselle Catherine Yu Madamba, Gabriel Gastaminza Lasarte P173 The role of basophil activation test in the diagnosis of immediate type drug hypersensitivity to betalactam antibiotics Antonia Thinnes, Hans F. Merk, Jens Malte Baron, Martin Leverkus, Galina Balakirski Poster walk 20: TCR recognition, cellular (P174–P183) P174 Characterisation of the effect of co-inhibitory signalling on the activation of drug-derived antigen-specific T-cells Andrew Gibson, Monday Ogese, Lee Faulkner, B. Kevin Park, Dean J. Naisbitt P175 Characterization of drug hapten-specific T cell responses in piperacillin hypersensitive patients Zaid Al-Attar, Fiazia Yaseen, Xiaoli Meng, Rozalind Jenkins, Paul Whitaker, Daniel Peckham, Lee Faulkner, John Farrel, Kevin Park, Dean Naisbitt P176 Characterization of the response of T-cells to telaprevir and its metabolite in normal volunteers Zaid Al-Attar, Khetam Alhilali, Yanni Xue, John Farrell, Lee Faulkner, Kevin Park, Dean Naisbitt P177 Characterization of the T cell receptor signatures of drug-responsive T cells Patricia Illing, Nicole Mifsud, Heidi Fettke, Jeffrey Lai, Rebecca Ho, Patrick Kwan, Anthony Purcell P178 Defining the signals between hepatocytes and immune cells in idiosyncratic drug-induced liver injury (DILI) Monday O. Ogese, Lee Faulkner, B. Kevin Park, Catherine Betts, Dean J. Naisbitt P179 Development of novel chemicals that do not bind to HLA-B*57:01 or activate CD8 + T-cells through modification of the 6-amino cyclopropyl group of abacavir Paul Thomson, John Farrell, Mohammad Alhaidari, Neill Berry, Paul M. O’Neill, B. Kevin Park, Dean J. Naisbitt P180 Generation and characterization of dapsone- and nitroso-dapsone-specific T-cell clones using lymphocytes from healthy volunteers Abdulaziz Alzahrani, Monday O. Ogese, John Farrell, Lee Faulkner, Andrew Gibson, Arun Tailor, B. Kevin Park, Dean J. Naisbitt P181 Identification of benzylpenicillin-hapten peptides responsible for naïve T-cell activation and immunization of allergic patients to penicillin Marie Eliane Azoury, Lucia Fili, Rami Bechara, Noémie Scornet, Cathy Nhim, Richard Weaver, Nancy Claude, Delphine Joseph, Bernard Maillere, Paola Parronchi, Marc Pallardy P182 Massive expansion of clonotypic and polycytotoxic CD8+ T cells in toxic epidermal necrolysis Axel Patrice Villani, Aurore Rozières, Benoît Bensaïd, Mathilde Tardieu, Floriane Albert, Virginie Mutez, Tugba Baysal, Marc Pallardy, Janet Maryanski, Jean-François Nicolas, Osami Kanagawa, Marc Vocanson P183 Pharmaco-immunological synapse of HLA-drug-TCR in SCAR Shuen-Iu Hung Poster walk 21: new in vitro methods, haptens, etc. (P184–P194) P184 Amoxicillin-clavulanate forms distinct multiple haptenic structures on human serum albumin in patients Xiaoli Meng, Arun Tailor, Caroline J. Harrison, Rosalind E. Jenkins, Paul Whitaker, Neil S. French, Dean J. Naisbitt, B. Kevin Park P185 Dendrimeric antigens for studying the influence of penicillin determinants orientation on IgE recognition Maria Isabel Montañez, Cristobalina Mayorga, Francisco Najera, Adriana Ariza, Tahia D. Fernandez, Maria Salas, Angela Martin-Serrano, Miguel Blanca, Ezequiel Perez-Inestrosa, Maria Jose Torres P186 Dendrimeric antigens on solid supports: designed materials for IgE quantification Yolanda Vida, Maria Isabel Montañez, Noemi Molina, Daniel Collado, Francisco Najera, Adriana Ariza, Maria Jose Torres, Cristobalina Mayorga, Ezequiel Perez-Inestrosa P187 Development of a screening assay for drug hypersensitivity using naïve T cells from donors with seven different HLA class I risk alleles Lee Faulkner, Sally Wood, Ana Alfirevic, Munir Pirmohamed, Dean J. Naisbitt, B. Kevin Park P188 Different patterns of recognition of structures derived from amoxicillin by IgE antibodies from patients with immediate hypersensitivity reactions to betalactams Adriana Ariza, Cristobalina Mayorga, María Isabel Montañez, María Salas, Inmaculada Doña, Ángela Martín-Serrano, Ezequiel Pérez-Inestrosa, Dolores Pérez-Sala, Miguel Blanca, Antonio E. Guzmán, María José Torres P189 High-resolution typing of HLA polymorphism and T-cell receptor repertoire for severe adverse drug reactions based on the cost-effective next-generation sequencing approaches Tai-Ming Ko, Yuan-Tsong Chen, Jer-Yuarn Wu P190 Identification and fate of intracellular proteins haptenated by amoxicillin Francisco J. Sánchez-Gómez, Juan M. González-Morena, Yolanda Vida, Ezequiel Pérez-Inestrosa, Miguel Blanca, María J. Torres, Dolores Pérez-Sala P191 In vitro detection of terbinafine protein adducts Arun Tailor, Toru Usui, Yanni Xue, Xiaoli Meng, Dean J. Naisbitt, B. Kevin Park P192 MicroRNAs dysregulation in PBMCs from drug hypersensitivity patients during drug challenge in vitro Alejandra Monroy Arreola, Jesus Agustin Badillo Corona, Silvia Mendez Flores, Judith Dominguez Cherit, Dean J. Naisbitt, Noe Valentin Duran Figueroa, Jose Luis Castrejon Flores P193 NSAIDs-exacerbated cutaneous disease: high throughput gene expression profiling José Antonio Cornejo-García, James Perkins, Natalia Blanca-López, Diana Pérez-Alzate, Raquel Jurado-Escobar, Inmaculada Doña, Gador Bogas, María J. Torres, Gabriela Canto, Miguel Blanca P194 Utility of skin tests in non-immediate reactions to amoxicillin Luis Mario Tubella Marti, Fernando Pineda De La Losa, Francisca Arribas Poves, Jaime Tubella Lopez, Teodora Lopez Santiag
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
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- Abdel-Aziz Amal Kamal
- Abdelfatah Sara
- Abdellatif Mahmoud
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- Zou Weiping
- Zou Zhen
- Zou Zhengzhi
- Zuryn Steven
- Zwerschke Werner
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field