1,181 research outputs found
THE COMPARATIVE ABILITY OF THE BOB-WHITE AND THE RING-NECKED PHEASANT TO WITHSTAND COLD AND HUNGER
The native Bob-white (Colinus virginianus) and the introduced Ring-necked Pheasant (Phasianus colchicus torquatus) may both, on occasion, suffer severe winter mortality over much of their common range in north-central United States. Their habitats often overlap, although the Pheasant has a greater cruising radius and an ability to live in a more open type of country than the Bob-white. In given localities they also live upon much the same kinds of winter foods. The scope of this paper is not intended to cover the ecological adjustments of Pheasants or of Bob-whites to their winter environment so much as the manifest effects of cold and malnutrition upon these birds under extreme conditions. Data upon which this paper is based were, for the most part, obtained incidentally, in connection with a number of field study and experimental projects in Iowa and Wisconsin, chiefly between 1929 and 1934. Certain apparent hiatuses attributable to the incidental origin of the data would doubtless yield to specifically directed experimentation, but the latter I am not in a position to carry on and probably will not be, at least for some years to come. In the meantime, it may be of biological interest and possible value to wildlife management to summarize the data already available on the comparative hardiness of Bob-whites and Pheasants
Muskrats in the Corn
If you happen to be one of the Iowa farmers who in recent years has had some trouble with muskrat damage in your cornfield along a creek, dredge ditch or the like and had asked Dr. Paul L. Errington of Iowa State College to come out and look over the situation to help you, the following story might be about what he would say to you Dr. Errington had in mind just such a situation when writing this story so that he might talk to you in a natural way
The Bounty System in Iowa
A study of the history and functioning of the bounty system in Iowa demonstrates the legal weaknesses, costliness, and general ineffectiveness of this method of controlling undesired wildlife. The bounty laws have developed by trial and error. Early laws were simplified and primarily intended for the protection of livestock from the larger predators, notably wolves. After 1900, the program was expanded to include nuisance species and, more recently, in intended behalf of game protection. Bounty rates were changed many times in response to changes in attitudes toward troublesome wildlife and the cost of maintaining the program. Because of bounty frauds, wastefulness, and the technical ineffectiveness of this type of program in wildlife management, it is advocated that more modern methods be used, such as extension teaching programs in localities where troubles with wildlife are serious
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Ultrastructural Distribution of the 7 Nicotinic Acetylcholine Receptor Subunit in Rat Hippocampus
Acetylcholine (ACh) is an important neurotransmitter in the mammalian brain; it is implicated in arousal, learning, and other cognitive functions. Recent studies indicate that nicotinic receptors contribute to these cholinergic effects, in addition to the established role of muscarinic receptors. In the hippocampus, where cholinergic involvement in learning and memory is particularly well documented, 7 nicotinic acetylcholine receptor subunits (7 nAChRs) are highly expressed, but their precise ultrastructural localization has not been determined. Here, we describe the results of immunogold labeling of serial ultrathin sections through stratum radiatum of area CA1 in the rat. Using both anti-7 nAChR immunolabeling and -bungarotoxin binding, we find that 7 nAChRs are present at nearly all synapses in CA1 stratum radiatum, with immunolabeling present at both presynaptic and postsynaptic elements. Morphological considerations and double immunolabeling indicate that GABAergic as well as glutamatergic synapses bear 7 nAChRs, at densities approaching those observed for glutamate receptors in CA1 stratum radiatum. Postsynaptically, 7 nAChRs often are distributed at dendritic spines in a perisynaptic annulus. In the postsynaptic cytoplasm, immunolabeling is associated with spine apparatus and other membranous structures, suggesting that 7 nAChRs may undergo dynamic regulation, with insertion into the synapse and subsequent internalization. The widespread and substantial expression of 7 nAChRs at synapses in the hippocampus is consistent with an important role in mediating and/or modulating synaptic transmission, plasticity, and neurodegeneration
The Northern Bob-White\u27s winter territory
This bulletin attempts to bring up to date our knowledge o[ individual covey ranges or wintering territories of the bobwhite quail [Colinus virginianus virginianus (Linn.)] (Fig. 1.)
It is based upon all of the pertinent and reliable data upon the subject at hand, of whatever origin and whatever degree of previous publication. Pertinence and reliability constitute the sole criteria by which we have attempted to judge the eligibility of data used, whether the data support our principal conclusions or not
The great horned owl and its prey in north-central United States
Along with other predatory species, the great horned owl has been studied in north-central United States, particularly in Iowa and southern Wisconsin localities in which ecological research upon certain prey types has been carried on contemporaneously. After investigation by field and laboratory methods involving experimentation with captive horned owls and observation in nature, it became obvious that the mass data on feeding trends required by the program could be best obtained through pellet studies supplemented by whatever additional techniques would yield information.
The horned owl food habits data upon which this bulletin is partly based were gathered largely between 1930 and 1935 and were the product of experience with 84 horned owl nests, examination of 4,815 pellets and 23 food-containing stomachs and records of direct predation. The prey types studied were chiefly upland game birds, waterfowl and fur-bearers, though many other forms were observed incidentally. The general procedure was to continue, so far as feasible, work on predation and population year after year on specific areas and to correlate the data from both; in this way, not only have some of the reasons for pronounced changes in food habits of predators become evident, but a superior background for evaluating effects of predation upon population levels of prey species has also resulted
A coupled drug kinetics-cell cycle model to analyse the response of human cells to intervention by topotecan
A model describing the response of the growth of single human cells in the absence and presence of the anti-cancer agent topotecan (TPT) is presented. The model includes a novel coupling of both the kinetics of TPT and cell cycle responses to the agent. By linking the models in this way, rather than using separate (disjoint) approaches, it is possible to illustrate how the drug perturbs the cell cycle. The model is compared to experimental in vitro cell cycle response data (comprising single cell descriptors for molecular and behavioural events), showing good qualitative agreement for a range of TPT dose levels
Identifying the active ingredients of training interventions for healthcare professionals to promote and support increased levels of physical activity in adults with heart failure: a systematic review
Heart failure (HF) is characterised by breathlessness and fatigue that impacts negatively on patients’ intentions to prioritise physical activity (PA). Healthcare professionals (HCPs) experience challenges when motivating patients to increase PA. It is essential to develop an understanding of how to support HCPs to deliver PA interventions. We aimed to identify active ingredients of HCP training interventions to enable delivery of PA interventions to HF patients. Nine databases were searched. Data were extracted on study characteristics, active ingredients, outcomes, and fidelity measures. Data were synthesised narratively, and a promise analysis was conducted on intervention features. Ten RCTs, which reported a training intervention for HCPs were included (N = 22 HCPs: N = 1,414 HF patients). Two studies reported the use of theory to develop HCP training. Seven behaviour change techniques (BCTs) were identified across the 10 training interventions. The most ‘promising’ BCTs were ‘instruction on how to perform the behaviour’ and ‘problem solving’. Two studies reported that HCP training interventions had been formally evaluated. Fidelity domains including study design, monitoring and improving the delivery of treatment, intervention delivery, and provider training were infrequently reported. Future research should prioritise theory-informed development and robust evaluation of training interventions for HCPs to enable faithful and quality delivery of patient interventions
Service user perspectives on social prescribing services for mental health in the UK: a systematic review
Aim: To thematically synthesise adult service users’ perspectives on how UK-based social prescribing services support them with their mental health management. Methods: Nine databases were systematically searched up to March 2022. Eligible studies were qualitative or mixed methods studies involving participants aged ⩾ 18 years accessing social prescribing services primarily for mental health reasons. Thematic synthesis was applied to qualitative data to create descriptive and analytical themes. Results: 51,965 articles were identified from electronic searches. Six studies were included in the review (n = 220 participants) with good methodological quality. Five studies utilised a link worker referral model, and one study a direct referral model. Modal reasons for referral were social isolation and/or loneliness (n = 4 studies). Two analytical themes were formulated from seven descriptive themes: (1) person-centred care was key to delivery and (2) creating an environment for personal change and development. Conclusions: This review provides a synthesis of the qualitative evidence on service users’ experiences of accessing and using social prescribing services to support their mental health management. Adherence to principles of person-centred care and addressing the holistic needs of service users (including devoting attention to the quality of the therapeutic environment) are important for design and delivery of social prescribing services. This will optimise service user satisfaction and other outcomes that matter to them. Keywords: systematic review, social prescribing, qualitative synthesis, mental health, public health, primary car
Barriers and facilitators of adherence to low-dose aspirin during pregnancy: A co-produced systematic review and COM-B framework synthesis of qualitative evidence
Copyright: \ua9 2024 Vinogradov et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. INTRODUCTION: Women at increased risk of developing pre-eclampsia are advised to take a daily low-dose of aspirin from 12 weeks of pregnancy to reduce their risks. Despite the well-established prophylactic effect of aspirin, adherence to this therapy is low. This systematic review aimed to summarise evidence on the barriers and facilitators of adherence to low-dose aspirin to inform intervention development to support decision making and persistence with aspirin use for pre-eclampsia prevention. MATERIALS AND METHODS: A systematic review and meta-synthesis of qualitative research was co-produced by representatives from charities, and public, clinical and academic members. Eight electronic databases (MEDLINE, PsycINFO, CINAHL, Web of Science, Scopus, EMBASE, Prospero, OpenGrey), archives of charities and professional organisations were searched (between October and November 2023 and re-run in August 2023) using predefined search terms. Studies containing qualitative components related to barriers and facilitators of adherence to low-dose aspirin during pregnancy were included. Quality assessment was performed using the Critical Appraisal Skills Programme checklist for qualitative research. A combination of the COM-B framework with phases of adherence process as defined by international taxonomy was used as the coding framework. Co-production activities were facilitated by use of \u27Zoom\u27 and \u27Linoit\u27. RESULTS: From a total of 3377 papers identified through our searches, five published studies and one dissertation met our inclusion criteria. Studies were published from 2019 to 2022 covering research conducted in the USA, Canada, UK, Netherlands and Australia. Barriers and facilitators to adherence were mapped to six categories of the COM-B for three phases of adherence: initiation, implementation, and discontinuation. The discontinuation phase of adherence was only mentioned by one author. Four key themes were identified relating to pregnancy: \u27Insufficient knowledge\u27, \u27Necessity concerns balance\u27, \u27Access to medicine\u27, \u27Social influences\u27, and \u27Lack of Habit\u27. CONCLUSIONS: The COM-B framework allowed for detailed mapping of key factors shaping different phases of adherence in behavioural change terms and now provides a solid foundation for the development of a behavioural intervention. Although potential intervention elements could be suggested based on the results of this synthesis, additional co-production work is needed to define elements and plan for the delivery of the future intervention. TRIAL REGISTRATION: PROSPERO CRD42022359718. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022359718
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