Effects of etofenamate and methylprednısolone on spınal cord ınjury

This study evaluates the effects of etofenamate on secondary damage following a spinal cord injury and compares the effects with those of methylprednisolone. A total of 31 male Wistar-Albino rats were used. A weight-drop model was utilized for the experimental spinal cord injury and a 50g-cm impact was applied on the spinal cord. Rats were randomly assigned to one of the three study arms (saline, etofenamate 20 mg/kg, methylprednisolone 30 mg/kg). At the sixth hour of injury electrophysiological evaluations were conducted under anesthesia, and then rats were sacrificed for histopathology. Hematoxylin and eosin staining were applied to the specimens and evaluated under light microscopy. Etofenamate revealed more beneficial results in histopathological evaluations when compared with methylprednisolone, but these favorable results have not been confirmed by electrophysiological measurements. Etofenamate may be a promising agent in the medical treatment of spinal cord injury

Experıence On Surgıcal Treatment Of Sıngle-Level Thoracıc Dısc Hernıatıons Vıa Costotransversectomy Approach

Amaç: Kostotransversektomi yaklaşımı ile tedavi edilen tek seviyeli torakal disk hernisi hastalarının sonuçlarını sunmak ve yaklaşımın avantaj ve dezavantajlarını tartışmak. Hastalar ve Yöntem: 2004 ve 2011 yılları arasında kostotransversektomi yöntemi ile ameliyat edilen 21 hastanın disk seviyeleri, geliş yakınmaları, izlem süresinde bulgu ve belirtilerindeki düzelmeler ve komplikasyon oranları sunuldu.Sonuçlar: Genel komplikasyon oranı komplike olay bazında % 38, hasta topluluğu bazında ise %19 olarak hesaplandı. En sık başvuru yakınması ağrı olup aksiyal, bölgesel ya da radiküler olarak görülebilmektedir. En yüksek iyileşme oranı ağrı yakınmasında izlenmiştir. Bu yaklaşımda ameliyat süresi kısa, kan kaybı azdır.Son Çıkarım: Kostotransversektomi iyi bir posterolateral görüş sağlayan, güvenli, kolay, az invaziv bir yaklaşım olarak torakal disk hernilerinin cerrahi tedavisinde ilk sıralarda akılda bulundurulması gereken bir yöntemdirObjective: To present the surgical results of the patients who have single-level thoracic disc herniation treated by costotransversectomy approach and to discuss advantages and disadvantages of this method.Patients and Method: Presenting symptoms, signs, recovery of symptoms after surgery and complication rates of twenty-one consecutive patients with single-level thoracic disc herniation treated via costotransversectomy in between 2004 and 2010 were presented. Results: Overall complication rate is 38% based on complicated events, and 19% based on patient population. The most common presenting symptom was axial, localized or radicular pain. The highest recovery rate was detected for pain. Operating time was short and blood loss was minimal for this method of operation.Conclusions: Costotransversectomy should be kept in mind as a first line surgical option due to its safety and less invasiveness. It provides excellent posterolateral vision to surgeo

Experıence On Surgıcal Treatment Of Sıngle-Level Thoracıc Dısc Hernıatıons Vıa Costotransversectomy Approach

Amaç: Kostotransversektomi yaklaşımı ile tedavi edilen tek seviyeli torakal disk hernisi hastalarının sonuçlarını sunmak ve yaklaşımın avantaj ve dezavantajlarını tartışmak. Hastalar ve Yöntem: 2004 ve 2011 yılları arasında kostotransversektomi yöntemi ile ameliyat edilen 21 hastanın disk seviyeleri, geliş yakınmaları, izlem süresinde bulgu ve belirtilerindeki düzelmeler ve komplikasyon oranları sunuldu.Sonuçlar: Genel komplikasyon oranı komplike olay bazında % 38, hasta topluluğu bazında ise %19 olarak hesaplandı. En sık başvuru yakınması ağrı olup aksiyal, bölgesel ya da radiküler olarak görülebilmektedir. En yüksek iyileşme oranı ağrı yakınmasında izlenmiştir. Bu yaklaşımda ameliyat süresi kısa, kan kaybı azdır.Son Çıkarım: Kostotransversektomi iyi bir posterolateral görüş sağlayan, güvenli, kolay, az invaziv bir yaklaşım olarak torakal disk hernilerinin cerrahi tedavisinde ilk sıralarda akılda bulundurulması gereken bir yöntemdirObjective: To present the surgical results of the patients who have single-level thoracic disc herniation treated by costotransversectomy approach and to discuss advantages and disadvantages of this method.Patients and Method: Presenting symptoms, signs, recovery of symptoms after surgery and complication rates of twenty-one consecutive patients with single-level thoracic disc herniation treated via costotransversectomy in between 2004 and 2010 were presented. Results: Overall complication rate is 38% based on complicated events, and 19% based on patient population. The most common presenting symptom was axial, localized or radicular pain. The highest recovery rate was detected for pain. Operating time was short and blood loss was minimal for this method of operation.Conclusions: Costotransversectomy should be kept in mind as a first line surgical option due to its safety and less invasiveness. It provides excellent posterolateral vision to surgeo

Erişkin Türk Toplumunda Odontoid Vida Uzunluğu: Morfometrik Bir Çalişma

C1, C2 düzeyinde yapılacak sabitlemede aksiyal rotasyonu korumak için anterior odontoid vidası kullanılmaktadır. Bu morfometrik çalışma erişkin Türk toplumunda uygun anterior odontoid vidası boyunu belirlemektir. Vida yolu ölçümleri T1-A midsagittal MRG üzerinde yapılmıştır. Vida yolunun ortalama uzunluğu 3.520.81 cm. dir. Sıklıkla kullanılan 35 mm. vidalar toplumun yarısı ıçın uygun olduğu belirlenmiştirAnterior placement of a screw for fixation of an odontoid fracture is performed to maintain axial rotation at the C1, C2 level. This morphometric study was performed to determine the length of anterior odontoid screw trajectory in adult Turkish population. Measurement of the trajectory length was performed on midsagittal T1-W sequence of MRI. Overall average length is 3.52±0.81 cm. Commonly used 35 mm screws are suitable for approximately half of the populatio

THE EFFECT OF PREOPERATIVE CERVICAL SAGITTAL ALIGNMENT ON POSTOPERATIVE SURGICAL RESULTS IN PATIENTS TREATED BY ANTERIOR CERVICAL DISCECTOMY AND FUSION

Objective: Cervical degenerative disc diseases arise in some degenerative settings. These degenerative cervical changes may be a consequenceof cervical sagittal malalignment. The aim of this study is to assess preoperative profile and postoperative changes in cervical sagittal profiles;and correlation between these changes and surgical outcomes in patients undergoing anterior cervical discectomy and fusion.Materials and Methods: Eighty consecutive men and women who underwent anterior cervical discectomy and fusion (ACDF) were enrolled inthe study. Cervical alignment was classified into 4 types-lordotic, flat, sigmoid, and kyphotic. Lordosis angle was measured by the Cobb method.Segmental angle at the level of discectomy was measured. Preoperative, early postoperative, and the 1st and 3rd month visual analog scale resultswere recorded. Improvement of cervical sagittal alignment and visual analogue scale (VAS) changes were compared statistically.Results: The median preoperative VAS score was 7. This score decreased to 1 as a median immediately after operation. This change was statisticallysignificant. Sagittal alignment changes in early postoperative period were not statistically significant despite the observation of improvement insome patients. However, after 1st and 3rd months, results showed significant improvements.Conclusion: ACDF is an effective treatment of cervical degenerative disc diseases (CDDD). Decompression is still the main issue of the degenerativecervical diseases. Sagittal alignment may be restored by using lordotic cages. Patients with F sagittal shape may tend to develop CDDD more thanN sagittal profile. There is a correlation between clinical improvement and radiologic improvement

USE OF BETA-TRICALCIUM PHOSPHATE WITH BONE MARROW ASPIRATE AS A BONE GRAFT SUBSTITUTE IN POSTEROLATERAL LUMBAR FUSION

Objective: Retrospective clinical study. This study aimed to determine the bony fusion rate of posterior lumbar fusion (PLF) involving betatricalciumphosphate (ß-TCP) and bone marrow aspirate (BMA). Bone fusion remains the main component of primary surgical approach for severalspinal disorders. Spine surgeons face the need to make crucial decisions regarding bone graft selection in each case.Materials and Methods: The study included 33 patients (21 female and 12 male patients) who underwent posterior lumbar pedicle screw fixationand fusion using ß-TCP as a bone substitute. The mean patient age was 58.35 (range=35-81) years.Results: The mean follow-up duration was 23.45 months. Solid bony fusion at the lateral side of the lumbar region between transverse processeswas noted on radiography in 24 patients (72.7%), bony bridging between adjacent transverse processes in 5 patients (15.2%), and no new boneformation in the remaining 4 patients (12.1%).Conclusion: The bony fusion rate of PLF involving ß-TCP and BMA was relatively high at 72.7%. ß-TCP is an effective and appropriate material forPLF in the lumbar area when used with BMA, and approximately 10 mL of ß-TCP per vertebral segment is sufficient

CORRELATION BETWEEN SPINOPELVIC PARAMETERS AND THE DEVELOPMENT OF LUMBAR DISC HERNIATION

Objective: The present study aimed to identify the correlation between spinopelvic parameters and the development of lumbar disc herniation,which is a condition usually surgically treated.Materials and Methods: A total of 147 consecutive patients with low back pain were divided into two groups according to treatment withmicrodiscectomy or treatment with some medications. In all patients, pelvic incidence (PI), lumbar lordosis (LL), sacral slope (SS), and pelvic tilt(PT) angles were measured on standing profile roentgenograms of the lumbar spine and pelvis. Statistical differences were investigated betweenthe two groups.Results: The PI, LL, and SS values were significantly different between the two groups. However, the difference in terms of PT was not significant.Conclusion: Some spinopelvic parameters, such as PI, LL, SS, and PT, may be considered as predictive factors in the development of degenerativespinal diseases, and the restoration of sagittal balance may provide better results when these factors are considered

Relation Between Cervical Sagittal Alignment And Surgical Outcome For Laminectomy And Posterior Fusion Operations

Servikal sagittal denge ve dizilim radyolojik ve klinik sonuçlarda oynadığı rol ile son zamanlarda dikkat çekmektedir. Bu çalışmanın amacı bazı servikal patolojiler nedeniyle laminektomi ve enstrümanlı füzyon yapılan hastalarda servikal sagittal denge değişimlerini ve bunun sonuçlara etkisini araştırmaktır. Retrospektif olarak düzenlenmiş bu çalışmada çeşitli derece ve seviyelerde kanal darlığı olan 44 erkek ve 6 kadın hasta yer almışlardır. Ameliyat öncesi ve sonrası mJOA derecesi ortalama değerleri sırasıyla 7.76 ve 12.96 'dur. Servikal lordoz açısı (CLA) değişimi istatistiksel olarak anlamlı olmakla beraber C2-7SVA değişimi istatistiksel olarak anlamlı değildir. Servikal sagittal denge ve dizilim posterior dekompresyon ve enstrümanlı füzyon yapılması planlanan hastalarda cerrahi sonuçlar değerlendirilirken mutlaka göz önüne alınmalıdır.Cervical sagittal balance and alignment have received increased awareness as important factors of radiological and clinical outcomes. The goal of this study is to evaluate preoperative and postoperative alterations in cervical sagittal plane situations and correlation between these changings and surgical outcome in patients undergo laminectomy and fusion for some cervical pathologies. In this retrospectively designed study 44 men and 6 women with some degree cervical stenosis at various cervical levels were included. The mean value of the preoperative and postoperative mJOA scores of the patients were 7.76 and 12.96 respectively. Cervical lordosis angle (CLA) changing was statistically significant after operations. But, C2-7SVA changing was not statistically significant. The contribution of cervical sagittal balance and alignment should be considered in evaluating surgical outcomes for patients undergoing cervical posterior decompression and instrumented fusion

Effectiveness of Preemptive Analgesia Using a Frequency Rhythmic Electrical Modulation System in Patients Having Instrumented Fusion for Lumbar Stenosis

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