18,077 research outputs found
Recovery From Design
Through research, inquiry, and an evaluation of Recovery By Design, a ‘design therapy’ program that serves people with mental illness, substance use disorders, and developmental disabilities, it is my assertion that the practice of design has therapeutic potential and can aid in the process of recovery. To the novice, the practices of conception, shaping form, and praxis have empowering benefit especially when guided by Conditional and Transformation Design methods together with an emphasis on materiality and vernacular form
Ground vibration test and flutter analysis of air sampling probe
The Dryden Flight Research Facility of NASA Ames Research Center conducted a ground vibration test and a flutter analysis of an air sampling probe that was to be mounted on a Convair 990 airplane. The probe was a steel, wing-shaped structure used to gather atmospheric data. The ground vibration test was conducted to update the finite-element model used in the flutter analysis. The analysis predicted flutter speeds well outside the operating flight envelope of the Convair 990 airplane
Experimental stagnation point velocity gradients and heat transfer coefficients for a family of blunt bodies at Mach 8 and angles of attack
Stagnation pressure and heat transfer measurements of blunt axisymmetric bodie
Drug Points: Apparent interaction between warfarin and levonorgestrel used for emergency contraception
No abstract available
The short-lived MATα2 transcriptional regulator is ubiquitinated in vivo
The substrates of ubiquitin-dependent proteolytic pathways include both damaged or otherwise abnormal proteins and undamaged proteins that are naturally short-lived. Few specific examples of the latter class have been identified, however. Previous work has shown that the cell type-specific MAT-alpha-2 repressor of the yeast Saccharomyces cerevisiae is an extremely short-lived protein. We now demonstrate that alpha-2 is conjugated to ubiquitin in vivo. More than one lysine residue of alpha-2 can be joined to ubiquitin, and some of the ubiquitin moieties form a Lys48-linked multiubiquitin chain. Overexpression of degradation-impaired ubiquitin variants was used to show that at least a significant fraction of alpha-2 degradation is dependent on its ubiquitination
Prediction, Retrodiction, and The Amount of Information Stored in the Present
We introduce an ambidextrous view of stochastic dynamical systems, comparing
their forward-time and reverse-time representations and then integrating them
into a single time-symmetric representation. The perspective is useful
theoretically, computationally, and conceptually. Mathematically, we prove that
the excess entropy--a familiar measure of organization in complex systems--is
the mutual information not only between the past and future, but also between
the predictive and retrodictive causal states. Practically, we exploit the
connection between prediction and retrodiction to directly calculate the excess
entropy. Conceptually, these lead one to discover new system invariants for
stochastic dynamical systems: crypticity (information accessibility) and causal
irreversibility. Ultimately, we introduce a time-symmetric representation that
unifies all these quantities, compressing the two directional representations
into one. The resulting compression offers a new conception of the amount of
information stored in the present.Comment: 17 pages, 7 figures, 1 table;
http://users.cse.ucdavis.edu/~cmg/compmech/pubs/pratisp.ht
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