Synthesis of Some New Tetracyclic Pyrimidine Derivatives Using Exocyclic α,β-Unsaturated Ketone and Evaluation of Their Antitumor Activities

Thiazolopyrimidine 2 was obtained from the reaction of dihydropyrimidinone with chloroacetic acid and benzaldehyde. Thiazolopyrimidine 2 containing an α,β-unsaturated ketonic function [-CH=CH-CO-] has been used as a component of Michael addition with an equimolar amount of dinucleophiles to give a series of novel tetracyclic pyrimidine derivatives. Treatment of thiazolopyrimidine 2 with uracil, aminotriazole, cyanoacetic acid hydrazide, o-phenylenediamine or diaminopyridine afforded the corresponding pyridopyrimidine, triazolopyrimidine, pyrazolone, benzodiazepine and triazepine derivative, respectively. The detailed synthesis, spectroscopic data, and antitumor activity for synthesized compounds were reported

DEBT SUSTAINABILIY AND ECONOMIC GROWTH IN EGYPT

The persistence growth of Egypt's public domestic debt has raised concerns regarding its impact on economic growth and fears are being express about the debt sustainability. Utilizing data for the period 1981-2006, the results obtained from cointegration model reveal that the public domestic debt in Egypt has a robust negative impact on growth. The sustainability of debt was examined used some algebra methods. The results suggested that the recent path of debt followed in Egypt was sustainable. For debt to remain sustained in future, substantial fiscal reforms are needed and policies should be adopting to maintain an increasing growth-interest rate differential.Public Domestic Debt; Fiscal Budget; Debt Sustainability; Economic Growth; Cointegration.

Recursive Detection of M-Ary Signals over Fast Varying Mobile Communication Channel

          Mobile radio is characterized by a fast time varying channel. Conventional detectors which designed optimal for non-fading channel exhibit a limited performance in fast time varying channel. In this paper a recursive detector for M-ary signals over fast time varying mobile communication channel is introduced. The proposed detector continuously estimates the channel directly within the metric calculation of the log-likelihood function in a recursive manner. The estimation of the channel is performed by the covariance form of the recursive least square approach. The performance of the detector is evaluated in terms of the misdetection probability. The effects of timing and phase offsets on the performance of detector are examined by simulation. Simulation results show that the proposed detector can accommodate the fast time varying channel with adequate performance

The compatibility of Yusuf Al Qaradawi\u27s wasateyya school of thought with the second generation of the Muslim Brotherhood

This paper aims to study the influence of the Wasateyya (centrist) school of thought on the Muslim Brotherhood\u27s second generation of leaders. The study shows that the Wasateyya school and its advocates within the Muslim Brotherhood were unsuccessful in bringing about a meaningful change in the direction of moderateness within the movement. The research assesses the influence of the Wasateyya school of thought by evaluating the compatibility of Qaradawi\u27s ideology with that of four members of the middle generation of the Brotherhood; Abd El Moniem Abul Fotouh, Essam el Eryan, Khairat al Shater, and Mohamed Morsi. The thesis is composed of seven large sections; sections one to three introduce the research question, methodology, and limitations. Section four is a literature review, section five addresses the relationship between Qaradawi and the second generation of the MB and defines ideological and political Wasateyya, section six is about the case study of the four leaders, and finally section seven concludes the main findings of the study

Low Complexity Selective Adaptive Multicarrier DS-CDMA Receiver

In this paper, selective adaptive (SA) receiver for Multicarrier Direct Sequence Code Division Multiple Access (MC DS-CDMA) system is presented. This receiver has high performance and at the same time reduces the multiple access interference (MAI) of the MC DS-CDMA) system with low computational complexity. The performance of SA receiver is measured in terms of the bit error rate (BER). An upper bound expression of the BER for the SA receiver under Rayleigh fading channel condition is derived and validated by computer simulations. Moreover, the implementation complexities of the SA receiver is compared with the Adaptive Parallel Interference Cancellation (APIC) receiver.

Disease Control of Pulmonary Inflammatory Pseudotumor by Multidisciplinary Approach

Introduction: Inflammatory pseudotumor is a rare tumor of the lung, which is usually misdiagnosed as malignancy. Most of early cases are treated with complete excision, but advanced cases: radiation therapy, steroids and chemotherapy will be a part of treatment plan. Multidisciplinary approach can save many cases of inflammatory pseudotumor and other rare diseases.Case Report: we reporting a case of advanced inflammatory pseudotumor with had a long disease control with multidisciplinary approach in the form of chemotherapy, steroids, radiation therapy and surgery.Conclusion: Advanced IP of the lung is rare disease with unknown etiology, where multidisciplinary team is needed for diagnosis and treatment: maximum safe debulking, chemotherapy, radiation therapy and steroids can be the suitable combined treatment for many advanced case