349 research outputs found
Photometry of the Stingray Nebula (V839 Ara) from 1889-2015 Across the Ionization of Its Planetary Nebula
Up until around 1980, the Stingray was an ordinary B1 post-AGB star, but then
it suddenly sprouted bright emission lines like in a planetary nebula (PN), and
soon after this the Hubble Space Telescope (HST) discovered a small PN around
the star, so apparently we have caught a star in the act of ionizing a PN. We
report here on a well-sampled light curve from 1889 to 2015, with unique
coverage of the prior century plus the entire duration of the PN formation plus
three decades of its aftermath. Surprisingly, the star anticipated the 1980's
ionization event by declining from B=10.30 in 1889 to B=10.76 in 1980. Starting
in 1980, the central star faded fast, at a rate of 0.20 mag/year, reaching
B=14.64 in 1996. This fast fading is apparently caused by the central star
shrinking in size. From 1994-2015, the V-band light curve is almost entirely
from the flux of two bright [OIII] emission lines from the unresolved nebula,
and it shows a consistent decline at a rate of 0.090 mag/year. This steady
fading (also seen in the radio and infrared) has a time scale equal to that
expected for ordinary recombination within the nebula, immediately after a
short-duration ionizing event in the 1980s. We are providing the first direct
measure of the rapidly changing luminosity of the central star on both sides of
a presumed thermal pulse in 1980, with this providing a strong and critical set
of constraints, and these are found to sharply disagree with theoretical models
of PN evolution.Comment: ApJ accepted, 54 pages, 4 figures, one long data tabl
The Effect of the Age-1 Gene on Lifespan in Caenorhabditis elegans
Caenorhabditis elegans has become one of the premiere model systems for aging research due to their accessible genome and their ease of cultivation. Their genome is small compared to humans yet it encodes over 22,000 proteins; about 35% of C. elegans genes are closely related to human genes. The age-1 gene codes for phosphatidylinositol 3-kinase, which is part of a pathway that regulates longevity. An RNAi feeding vector was created to silence the age-1 gene. My hypothesis is that the lifespan of the treated nematodes will decrease relative to the control. The effectiveness of my constructed RNAi feeding strain will be studied by performing lifespan assays
XMM-Newton Survey of the Brightest Supernova Remnants in the Large Magellanic Cloud
Therefore, a realistic understanding of SN contribution from SNRs populations is needed to model the evolution of a galaxy
Drought Stress Results in a Compartment-Specific Restructuring of the Rice Root-Associated Microbiomes.
Plant roots support complex microbial communities that can influence plant growth, nutrition, and health. While extensive characterizations of the composition and spatial compartmentalization of these communities have been performed in different plant species, there is relatively little known about the impact of abiotic stresses on the root microbiota. Here, we have used rice as a model to explore the responses of root microbiomes to drought stress. Using four distinct genotypes, grown in soils from three different fields, we tracked the drought-induced changes in microbial composition in the rhizosphere (the soil immediately surrounding the root), the endosphere (the root interior), and unplanted soils. Drought significantly altered the overall bacterial and fungal compositions of all three communities, with the endosphere and rhizosphere compartments showing the greatest divergence from well-watered controls. The overall response of the bacterial microbiota to drought stress was taxonomically consistent across soils and cultivars and was primarily driven by an enrichment of multiple Actinobacteria and Chloroflexi, as well as a depletion of several Acidobacteria and Deltaproteobacteria While there was some overlap in the changes observed in the rhizosphere and endosphere communities, several drought-responsive taxa were compartment specific, a pattern likely arising from preexisting compositional differences, as well as plant-mediated processes affecting individual compartments. These results reveal that drought stress, in addition to its well-characterized effects on plant physiology, also results in restructuring of root microbial communities and suggest the possibility that constituents of the altered plant microbiota might contribute to plant survival under extreme environmental conditions.IMPORTANCE With the likelihood that changes in global climate will adversely affect crop yields, the potential role of microbial communities in enhancing plant performance makes it important to elucidate the responses of plant microbiomes to environmental variation. By detailed characterization of the effect of drought stress on the root-associated microbiota of the crop plant rice, we show that the rhizosphere and endosphere communities undergo major compositional changes that involve shifts in the relative abundances of a taxonomically diverse set of bacteria in response to drought. These drought-responsive microbes, in particular those enriched under water deficit conditions, could potentially benefit the plant as they could contribute to tolerance to drought and other abiotic stresses, as well as provide protection from opportunistic infection by pathogenic microbes. The identification and future isolation of microbes that promote plant tolerance to drought could potentially be used to mitigate crop losses arising from adverse shifts in climate
The Effect of Patent Expiration on Pharmaceutical Firms’ Research and Development Decisions
How does the expiration of a pharmaceutical firms’ drug patent affect the firms’ R&D decisions? We attempt to answer this question by combining data from the FDA Orange Book dataset on drug patents with firm-level data from the Pharmaprojects database. We utilize a logistic probability model to determine how patent expiration affects the chances that a firm will undertake certain actions to mitigate the negative effects that patent expirations have on revenue streams. In doing so, we find that firms that are nearing patent expiration begin testing of new products and seek new licensing opportunities for existing products, rather than discontinue existing products.Bachelor of Art
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Comparative Analysis of Root Microbiomes of Rice Cultivars with High and Low Methane Emissions Reveals Differences in Abundance of Methanogenic Archaea and Putative Upstream Fermenters.
Rice cultivation worldwide accounts for ∼7 to 17% of global methane emissions. Methane cycling in rice paddies is a microbial process not only involving methane producers (methanogens) and methane metabolizers (methanotrophs) but also other microbial taxa that affect upstream processes related to methane metabolism. Rice cultivars vary in their rates of methane emissions, but the influence of rice genotypes on methane cycling microbiota has been poorly characterized. Here, we profiled the rhizosphere, rhizoplane, and endosphere microbiomes of a high-methane-emitting cultivar (Sabine) and a low-methane-emitting cultivar (CLXL745) throughout the growing season to identify variations in the archaeal and bacterial communities relating to methane emissions. The rhizosphere of the high-emitting cultivar was enriched in methanogens compared to that in the low emitter, whereas the relative abundances of methanotrophs between the cultivars were not significantly different. Further analysis of cultivar-sensitive taxa identified families enriched in the high emitter that are associated with methanogenesis-related processes. The high emitter had greater relative abundances of sulfate-reducing and iron-reducing taxa which peak earlier in the season than methanogens and are necessary to lower soil oxidation reduction potential before methanogenesis can occur. The high emitter also had a greater abundance of fermentative taxa which produce methanogenesis precursors (acetate, CO2, and H2). Furthermore, the high emitter was enriched in taxa related to acetogenesis which compete with methanogens for CO2 and H2 These taxa were enriched in a spatio-specific manner and reveal a complex network of microbial interactions on which plant genotype-dependent factors can act to affect methanogenesis and methane emissions.IMPORTANCE Rice cultivation is a major source of anthropogenic emissions of methane, a greenhouse gas with a potentially severe impact on climate change. Emission variation between rice cultivars suggests the feasibility of breeding low-emission rice, but there is a limited understanding of how genotypes affect the microbiota involved in methane cycling. Here, we show that the root microbiome of the high-emitting cultivar is enriched both in methanogens and in taxa associated with fermentation, iron, and sulfate reduction and acetogenesis, processes that support methanogenesis. Understanding how cultivars affect microbes with methanogenesis-related functions is vital for understanding the genetic basis for methane emission in rice and can aid in the development of breeding programs that reduce the environmental impact of rice cultivation
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Soil domestication by rice cultivation results in plant-soil feedback through shifts in soil microbiota.
BackgroundSoils are a key component of agricultural productivity, and soil microbiota determine the availability of many essential plant nutrients. Agricultural domestication of soils, that is, the conversion of previously uncultivated soils to a cultivated state, is frequently accompanied by intensive monoculture, especially in the developing world. However, there is limited understanding of how continuous cultivation alters the structure of prokaryotic soil microbiota after soil domestication, including to what extent crop plants impact soil microbiota composition, and how changes in microbiota composition arising from cultivation affect crop performance.ResultsWe show here that continuous monoculture (> 8 growing seasons) of the major food crop rice under flooded conditions is associated with a pronounced shift in soil bacterial and archaeal microbiota structure towards a more consistent composition, thereby domesticating microbiota of previously uncultivated sites. Aside from the potential effects of agricultural cultivation practices, we provide evidence that rice plants themselves are important drivers of the domestication process, acting through selective enrichment of specific taxa, including methanogenic archaea, in their rhizosphere that differ from those of native plants growing in the same environment. Furthermore, we find that microbiota from soils domesticated by rice cultivation contribute to plant-soil feedback, by imparting a negative effect on rice seedling vigor.ConclusionsSoil domestication through continuous monoculture cultivation of rice results in compositional changes in the soil microbiota, which are in part driven by the rice plants. The consequences include a negative impact on plant performance and increases in greenhouse gas emitting microbes
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