2,239 research outputs found
Effect of high temperature heat treatments on the quality factor of a large-grain superconducting radio-frequency niobium cavity
Large-grain Nb has become a viable alternative to fine-grain Nb for the
fabrication of superconducting radio-frequency cavities. In this contribution
we report the results from a heat treatment study of a large-grain 1.5 GHz
single-cell cavity made of "medium purity" Nb. The baseline surface preparation
prior to heat treatment consisted of standard buffered chemical polishing. The
heat treatment in the range 800 - 1400 C was done in a newly designed vacuum
induction furnace. Q0 values of the order of 2x1010 at 2.0 K and peak surface
magnetic field (Bp) of 90 mT were achieved reproducibly. A Q0-value of
(5+-1)1010 at 2.0 K and Bp = 90 mT was obtained after heat treatment at 1400 C.
This is the highest value ever reported at this temperature, frequency and
field. Samples heat treated with the cavity at 1400 C were analyzed by
secondary ion mass spectrometry, secondary electron microscopy, energy
dispersive X-ray, point contact tunneling and X-ray diffraction and revealed a
complex surface composition which includes titanium oxide, increased carbon and
nitrogen content but reduced hydrogen concentration compared to a non
heat-treated sample
Yields and Sward Characteristics of Timothy Cultivars under Grazing
Seven timothy (Phleum pratense L.) cultivars were evaluated over three pasture seasons under rotational grazing to 7 or 11 cm post-grazing heights and regrowth periods of four to seven weeks. There was a trend for the pasture type timothy cultivars to outyield Champ timothy (check). Dry matter yields were lower for the 7 cm than 11 cm post-grazing height. Although the overall cultivar x post-grazing height interaction was not significant (P \u3e 0.05), there was variability in grazing tolerance among timothy cultivars. Yield of Kahu was maintained and vegetative tiller density of Kahu increased over the experimental period under 7 cm grazing. Proportion of vegetative tillers among the cultivars ranged from 0.20 to 0.61 in the primary growth but this proportion increased to 0.95 in the fourth grazing
Erosion of Empathy in Primary Care Trainees
Objective:
To evaluate if empathy among physician residents (trainees) differs dependent on training year and to assess trainees\u27 characteristics associated with higher empathy scores.
Poster presented at 2016 ISPOR conference in Washington DC.https://jdc.jefferson.edu/jcphposters/1006/thumbnail.jp
Determination of the surface-potential barrier of Cu(001) from low-energy-electron-diffraction fine structure
Classification of hyperbolic Dynkin diagrams, root lengths and Weyl group orbits
We give a criterion for a Dynkin diagram, equivalently a generalized Cartan
matrix, to be symmetrizable. This criterion is easily checked on the Dynkin
diagram. We obtain a simple proof that the maximal rank of a Dynkin diagram of
compact hyperbolic type is 5, while the maximal rank of a symmetrizable Dynkin
diagram of compact hyperbolic type is 4. Building on earlier classification
results of Kac, Kobayashi-Morita, Li and Sa\c{c}lio\~{g}lu, we present the 238
hyperbolic Dynkin diagrams in ranks 3-10, 142 of which are symmetrizable. For
each symmetrizable hyperbolic generalized Cartan matrix, we give a
symmetrization and hence the distinct lengths of real roots in the
corresponding root system. For each such hyperbolic root system we determine
the disjoint orbits of the action of the Weyl group on real roots. It follows
that the maximal number of disjoint Weyl group orbits on real roots in a
hyperbolic root system is 4.Comment: J. Phys. A: Math. Theor (to appear
Paced left ventricular QRS width and ECG parameters predict outcomes after cardiac resynchronization therapy: PROSPECT-ECG substudy.
International audienceBACKGROUND: For patients with symptomatic New York Heart Association class III or IV, ejection fraction †35%, and QRS ℠130 ms, cardiac resynchronization therapy (CRT) has become an established treatment option. However, use of these implant criteria fails to result in clinical or echocardiographic improvement in 30% to 45% of CRT patients. METHODS AND RESULTS: The Predictors of Response to CRT (PROSPECT)-ECG is a substudy of the prospective observational PROSPECT trial. ECGs collected before, during, and after CRT implantation were analyzed. Primary outcomes were improvement in clinical composite score (CCS) and reduction of left ventricular end systolic volume (LVESV) of >15% after 6 months. Age, sex, cause of cardiomyopathy, myocardial infarction location, right ventricular function, mitral regurgitation, preimplantation QRS width, preimplantation PR interval, preimplantation right ventricular-paced QRS width, preimplantation axis categories, LV-paced QRS width, postimplantation axis categories, difference between biventricular (Bi-V) pacing and preimplantation QRS width, and QRS bundle branch morphological features were analyzed univariably in logistic regression models to predict outcomes. All significant predictors (α=0.1), age, and sex were used for multivariable analyses. Cardiomyopathy cause interaction and subanalyses were also performed. In multivariable analyses, only QRS left bundle branch morphological features predicted both CCS (odds ratio [OR]=2.46, P=0.02) and LVESV (OR=2.89, P=0.048) response. The difference between Bi-V and preimplantation QRS width predicted CCS improvement (OR=0.89, P=0.04). LV-paced QRS width predicted LVESV reduction (OR=0.86, P=0.01). Specifically, an LV-paced QRS width of †200 ms was predictive of nonischemic LVESV reduction (OR=5.12, P=0.01). CONCLUSIONS: Baseline left bundle branch QRS morphological features, LV-paced QRS width, and the difference between Bi-V and preimplantation QRS width can predict positive outcomes after CRT and may represent a novel intraprocedural method to optimize coronary sinus lead placement. CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT00253357
Observation of Squeezed Light in the 2ââÎm Region
We present the generation and detection of squeezed light in the 2ââÎŒm wavelength region. This experiment is a crucial step in realizing the quantum noise reduction techniques that will be required for future generations of gravitational-wave detectors. Squeezed vacuum is generated via degenerate optical parametric oscillation from a periodically poled potassium titanyl phosphate crystal, in a dual resonant cavity. The experiment uses a frequency stabilized 1984 nm thulium fiber laser, and squeezing is detected using balanced homodyne detection with extended InGaAs photodiodes. We have measured 4.0±0.1ââdB of squeezing and 10.5±0.5ââdB of antisqueezing relative to the shot noise level in the audio frequency band, limited by photodiode quantum efficiency. The inferred squeezing level directly after the optical parametric oscillator, after accounting for known losses and phase noise, is 10.7 dB
Examining the Impact of Imputation Errors on Fine-Mapping Using DNA Methylation QTL as a Model Trait
Genetic variants disrupting DNA methylation at CpG dinucleotides (CpG-SNP) provide a set of known causal variants to serve as models for testing fine-mapping methodology. We use 1716 CpG-SNPs to test three fine-mapping approaches (BIMBAM, BSLMM, and the J-test), assessing the impact of imputation errors and the choice of reference panel by using both whole-genome sequence (WGS), and genotype array data on the same individuals (n=1166). The choice of imputation reference panel had a strong effect on imputation accuracy, with the 1000 Genomes Phase 3 (1000G) reference panel (n=2504 from 26 populations) giving a mean non-reference discordance rate between imputed and sequenced genotypes of 3.2% compared to 1.6% when using the Haplotype Reference Consortium (HRC) reference panel (n=32470 Europeans). These imputation errors impacted on whether the CpG-SNP was included in the 95% credible set, with a difference of ⌠23% and ⌠7% between the WGS and the 1000G and HRC imputed datasets respectively. All of the fine-mapping methods failed to reach the expected 95% coverage of the CpG-SNP. This is attributed to secondary cis genetic effects that are unable to be statistically separated from the CpG-SNP, and through a masking mechanism where the effect of the methylation disrupting allele at the CpG-SNP is hidden by the effect of a nearby SNP that has strong LD with the CpG-SNP. The reduced accuracy in fine-mapping a known causal variant in a low level biological trait with imputed genetic data has implications for the study of higher order complex traits and disease
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