Integrating mitochondrial translation into the cellular context.

Mitochondrial-encoded subunits of the oxidative phosphorylation system assemble with nuclear-encoded subunits into enzymatic complexes. Recent findings showed that mitochondrial translation is linked to other mitochondrial functions, as well as to cellular processes. The supply of mitochondrial- encoded proteins is coordinated by the coupling of mitochondrial protein synthesis with assembly of respiratory chain complexes. MicroRNAs imported from the cytoplasm into mitochondria were, surprisingly, found to act as regulators of mitochondrial translation. In turn, translation in mitochondria controls cellular proliferation, and mitochondrial ribosomal subunits contribute to the cytoplasmic stress response. Thus, translation in mitochondria is apparently integrated into cellular processes

Writing Against Islamic Dramas. Islamisches Familienrecht neu denken

Starting from a brief discussion of current politics of “othering” at the intersection of culture, gender and sexuality, the present paper takes up critical perspectives from anthropological research and area studies in order, on the one hand, to point to the relevance of looking at transfers and interconnections, on the other hand, to understand how gender and constructions of cultural identity are historically enmeshed. With a view to demonstrating the pertinence of this perspective, examples from contemporary Muslim family law are analysed with a major focus on the Moroccan experience of reform

Charging Public Land Users for Recreational Uses

11 pages

Computational Aspects of Mixed Characteristic Witt Vectors and Denominators in Canonical Liftings of Elliptic Curves

Given an ordinary elliptic curve E over a field of characteristic p, there is an elliptic curve E over the Witt vectors W() for which we can lift the Frobenius morphism, called the canonical lifting of E. The Weierstrass coefficients and the elliptic Teichmüller lift of E are given by rational functions over _p that depend only on the coefficients and points of E. Finotti studied the properties of these rational functions over fields of characteristic p ≥ 5. We investigate the same properties for fields of characteristic 2 and 3, make progress on some conjectures of Finotti, and introduce some conjectures of our own. We also investigate the structure of rings of Witt vectors over arbitrary commutative rings and give a computationally useful isomorphism for Witt vectors over ℤ/p^αℤ [alpha]

Augmenting Graphical User Interfaces with Haptic Assistance for Motion-Impaired Operators

Haptic assistance is an emerging field of research that is designed to improve human-computer interaction (HCI) by reducing error rates and targeting times through the use of force feedback. Haptic feedback has previously been investigated to assist motion-impaired computer users, however, limitations such as target distracters have hampered its integration with graphical user interfaces (GUIs). In this paper two new haptic assistive techniques are presented that utilise the 3DOF capabilities of the Phantom Omni. These are referred to as deformable haptic cones and deformable virtual switches. The assistance is designed specifically to enable motion-impaired operators to use existing GUIs more effectively. Experiment 1 investigates the performance benefits of the new haptic techniques when used in conjunction with the densely populated Windows on-screen keyboard (OSK). Experiment 2 utilises the ISO 9241-9 point-and-click task to investigate the effects of target size and shape. The results of the study prove that the newly proposed techniques improve interaction rates and can be integrated with existing software without many of the drawbacks of traditional haptic assistance. Deformable haptic cones and deformable virtual switches were shown to reduce the mean number of missed-clicks by at least 75% and reduce targeting times by at least 25%

Guidelines for the design of haptic widgets

Haptic feedback has been shown to improve user performance in Graphical User Interface (GUI) targeting tasks in a number of studies. These studies have typically focused on interactions with individual targets, and it is unclear whether the performance increases reported will generalise to the more realistic situation where multiple targets are presented simultaneously. This paper addresses this issue in two ways. Firstly two empirical studies dealing with groups of haptically augmented widgets are presented. These reveal that haptic augmentations of complex widgets can reduce performance, although carefully designed feedback can result in performance improvements. The results of these studies are then used in conjunction with the previous literature to generate general design guidelines for the creation of haptic widgets

Pierce County Statistics on Labor Market Inequalities

This report presents a wide range of statistics on labor market inequalities by gender and race specific to Pierce County (Washington State). The analysis focuses on various measures of labor market outcomes: labor market participation rates, employment ratios, occupational structure, earnings, and poverty rates. These document the existing inequalities in the labor market. We also present data on some underlying pre-labor market causes of labor market inequalities: individuals’ educational attainment and family background characteristics. We give an overview of the available data sources, and summarize the key findings by gender and race. The statistics are presented as comparisons between Pierce County, King County, and Washington state, for the year 2018, as well as trends over time. We conclude the report by discussing avenues for further research based on the key questions that emerge, which could present the basis for better targeted local policymaking