699 research outputs found
Quantitative leak test design guide
Calibrated enclosure technique for rapid and accurate determination of leak rate
Search for tau neutrinos at PeV energies and beyond with the MAGIC telescopes
The MAGIC telescopes, located at the Roque de los Muchachos Observatory (2200
a.s.l.) in the Canary Island of La Palma, are placed on the top of a mountain,
from where a window of visibility of about 5 deg in zenith and 80 deg in
azimuth is open in the direction of the surrounding ocean. This permits to
search for a signature of particle showers induced by earth-skimming cosmic tau
neutrinos in the PeV to EeV energy range arising from the ocean. We have
studied the response of MAGIC to such events, employing Monte Carlo simulations
of upward-going tau neutrino showers. The analysis of the shower images shows
that air showers induced by tau neutrinos can be discriminated from the
hadronic background coming from a similar direction. We have calculated the
point source acceptance and the expected event rates, for a sample of generic
neutrino fluxes from photo-hadronic interactions in AGNs. The analysis of about
30 hours of data taken toward the sea leads to a point source sensitivity for
tau neutrinos at the level of the down-going point source analysis of the
Pierre Auger Observatory, if the AUGER observation time is dedicated to a
similar amount by MAGIC.Comment: Proceedings of EPS-HEP 2017, European Physical Society conference on
High Energy Physics, 5-12 July 2017, Venice, Italy. arXiv admin note:
substantial text overlap with arXiv:1708.0614
Sensitivity for tau neutrinos at PeV energies and beyond with the MAGIC telescopes
The MAGIC telescopes, located at the Roque de los Muchachos Observatory (2200
a.s.l.) in the Canary Island of La Palma, are placed on the top of a mountain,
from where a window of visibility of about 5 deg in zenith and 80 deg in
azimuth is open in the direction of the surrounding ocean. This permits to
search for a signature of particle showers induced by earth-skimming cosmic tau
neutrinos in the PeV to EeV energy range arising from the ocean. We have
studied the response of MAGIC to such events, employing Monte Carlo simulations
of upward-going tau neutrino showers. The analysis of the shower images shows
that air showers induced by tau neutrinos can be discriminated from the
hadronic background coming from a similar direction. We have calculated the
point source acceptance and the expected event rates, assuming an incoming tau
neutrino flux consistent with IceCube measurements, and for a sample of generic
neutrino fluxes from photo-hadronic interactions in AGNs. The analysis of about
30 hours of data taken toward the sea leads to a point source sensitivity for
tau neutrinos at the level of the down-going point source analysis of the
Pierre Auger Observatory.Comment: Proceedings of the 35th International Cosmic Ray Conference (ICRC
2017), Bexco, Busan, Korea,(arXiv:1708.05153
Unusual nanostructures of "lattice matched" InP on AlInAs
We show that the morphology of the initial monolayers of InP on
Al0.48In0.52As grown by metalorganic vapor-phase epitaxy does not follow the
expected layer-by-layer growth mode of lattice-matched systems, but instead
develops a number of low-dimensional structures, e.g., quantum dots and wires.
We discuss how the macroscopically strain-free heteroepitaxy might be strongly
affected by local phase separation/alloying-induced strain and that the
preferred aggregation of adatom species on the substrate surface and reduced
wettability of InP on AlInAs surfaces might be the cause of the unusual (step)
organization and morpholog
Integrating computational methods to predict mutagenicity of aromatic azo compounds
Azo dyes have several industrial uses. However, these azo dyes and their degradation products showed mutagenicity, inducing damage in environmental and human systems. Computational methods are proposed as cheap and rapid alternatives to predict the toxicity of azo dyes. A benchmark dataset of Ames data for 354 azo dyes was employed to develop three classification strategies using knowledge-based methods and docking simulations. Results were compared and integrated with three models from the literature, developing a series of consensus strategies. The good results confirm the usefulness of in silico methods as a support for experimental methods to predict the mutagenicity of azo compounds
Limits on light-speed anisotropies from Compton scattering of high-energy electrons
The possibility of anisotropies in the speed of light relative to the
limiting speed of electrons is considered. The absence of sidereal variations
in the energy of Compton-edge photons at the ESRF's GRAAL facility constrains
such anisotropies representing the first non-threshold collision-kinematics
study of Lorentz violation. When interpreted within the minimal Standard-Model
Extension, this result yields the two-sided limit of 1.6 x 10^{-14} at 95%
confidence level on a combination of the parity-violating photon and electron
coefficients kappa_{o+} and c. This new constraint provides an improvement over
previous bounds by one order of magnitude.Comment: 4 pages, 4 figure
Arterial Stiffness: Effects of Anticancer Drugs Used for Breast Cancer Women
Purpose: It is well known that anticancer drugs used for treating breast cancer can cause cardiac toxicity, and less is known about vascular toxicity. The aim of this study was to assess subclinical vascular effects of anthracyclines and trastuzumab (TRZ) in women treated for breast cancer. Methods: We enrolled 133 female patients with breast cancer undergoing adjuvant treatment with anthracycline-containing chemotherapy (CT) followed by taxane (paclitaxel/docetaxel) + TRZ. Patients underwent a standard echocardiography including measurement of left ventricular ejection fraction and global longitudinal strain at baseline and at follow-up. Vascular toxicity was evaluated by measuring brachial blood pressure (BP) and arterial stiffness indices (pulse wave velocity and Beta stiffness index) at T0 (baseline), T1 (3 months), T2 (6 months), and T3 (12 months). Results: Arterial stiffness indices were significantly increased at T1 in patients treated with anthracycline-containing CT (PWV 5.5 m/s IQR 5.15–6.4 at T0 vs. PWV 6.7 m/s IQR 5.6–7.2 at T1, p < 0.05; Beta index PWV 6.7 IQR 5.25–6.65 at T0, PWV 8.35 IQR 6.5–10.15 at T1, p < 0.05) but not at T2 and T3, when treatment with anthracyclines was stopped and patients were under treatment with taxane and TRZ. Blood pressure values did not significantly change during follow-up. Conclusion: Changes in arterial stiffness parameters occur early after starting treatment with anthracyclines, and they seem to be reversible if anthracycline treatment is stopped. These changes are not influenced by blood pressure values modifications. Therefore, in breast cancer women, anthracyclines seem to cause early reversible subclinical vascular injury
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