Um ranking das revistas científicas especializadas em economia regional e urbana

Sendo que há necessidade de conhecer a qualidade relativa das “revistas internacionais com avaliação” especializadas em economia regional e urbana, na literatura não existe tal listagem. Para colmatar esta lacuna, apresentamos neste trabalho uma hierarquização e uma classificação das 39 revistas cobertas pela base de dados bibliográfica ISI Web of Knowledge que têm no nome a palavra “Regional” ou “Urban” ou que pertencem a “Urban Studies”. Concluímos que a revista Journal of Urban Economics é a que tem maior índice de qualidade (0.058) que, apesar de ser relativamente muito elevado, é bastante menor que o índice de qualidade das revistas generalistas de topo que publicam artigos nesta área, i.e. a American Economic Review (0.194), a Econometrica (0.169) e o Journal of Business and Economic Statistics (0.118).Economia regional e urbana, Ranking de revistas científicas

Climacteric and sexuality

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The epidemiology and management of postmenopausal osteoporosis: a viewpoint from Brazil

Brazil has an aging population, with an associated increase in the prevalence of chronic diseases. Postmenopausal osteoporosis is of particular concern because it leads to an increased risk of fractures, with subsequent negative impacts on health in older women. In recent years, efforts have been made to better understand the epidemiology of osteoporosis in Brazil, and to manage both direct and indirect costs to the Brazilian health care system. The reported prevalence of osteoporosis among postmenopausal women in Brazil varies from 15% to 33%, depending on the study methodology and the use of bone densitometry data or self-reporting by participants. A diagnosis of osteoporosis can be made on the basis of fractures occurring without significant trauma or on the basis of low bone mineral density measured by dual energy X-ray absorptiometry. To reduce the risk of osteoporosis, all postmenopausal women should be encouraged to maintain a healthy lifestyle, which includes physical activity and a balanced diet. Smoking and alcohol use should also be addressed. Special attention should be given to interventions to reduce the risk of falls, especially among older women. Calcium intake should be encouraged, preferably through diet. The decision to recommend calcium supplementation should be made individually because there is concern about a possible increased risk of cardiovascular disease associated with this treatment. Brazilian women obtain a minimal amount of vitamin D from their diet, and supplementation is warranted in women with little exposure to solar ultraviolet-B radiation. For women diagnosed with osteoporosis, some form of pharmacologic therapy should be initiated. Compliance with treatment should be monitored, and the treatment period should be individualized for each patient. The Brazilian government provides medication for osteoporosis through the public health system free of charge, but without proper epidemiological knowledge, the implementation of public health programs is impaired.Brazil has an aging population, with an associated increase in the prevalence of chronic diseases. Postmenopausal osteoporosis is of particular concern because it leads to an increased risk of fractures, with subsequent negative impacts on health in older10583591sem informaçãosem informaçã

Qualidade de vida e sintomas da menopausa em mulheres transplantadas hepáticas

PURPOSE: To assess quality of life and climacteric symptoms in women with and without liver transplants. METHODS: This was a cross-sectional study of 52 women undergoing follow-up at a university hospital in southeastern Brazil from February 4th, 2009 to January 5th, 2011. Twenty-four of these women were 35 years old or older and had undergone liver transplantation at least one year before study entry. The remaining 28 women had no liver disease and were matched by age and menstrual patterns to the patients with transplants. The abbreviated version of the World Health Organization (WHOQOL-BREF) questionnaire was used to assess quality of life. Menopausal symptoms were assessed using the Menopause Rating Scale (MRS). Statistical analysis was carried out by Student's t-test, Mann-Whitney test and analysis of variance. Correlations between MRS and the WHOQOL-BREF were established by correlation coefficients. RESULTS: The mean age of the women included in the study was 52.2 (±10.4) years and the mean time since transplantation was 6.1 (±3.3) years. Women with liver transplants had better quality of life scores in the environment domain (p=0.01). No difference was noted between the two groups in any domain of the MRS. For women in the comparison group, there was a strongly negative correlation between somatic symptoms in the MRS and the physical domain of the WHOQOL-BREF (p<0.01; r=-0.8). In contrast, there was only a moderate association for women with liver transplants (p<0.01; r=-0.5). CONCLUSIONS: Women with liver transplants had better quality of life scores in the domain related to environment and did not exhibit more intense climacteric symptoms than did those with no liver disease. Climacteric symptoms negatively influenced quality of life in liver transplant recipients, although less intensely than in women without a history of liver disease.OBJETIVO: Avaliar a qualidade de vida e os sintomas do climatério em mulheres com e sem transplante de fígado. MÉTODOS: Estudo de corte transversal com 52 mulheres em acompanhamento ambulatorial em um hospital universitário na região sudeste do Brasil no período de 04/02/09 a 05/01/11. Dessas mulheres, 24 tinham 35 anos ou mais e haviam sido submetidas a transplante de fígado a pelo menos um ano antes do início do estudo. As outras 28 mulheres não tinham doença hepática e suas idades e padrões menstruais eram similares ao das transplantadas hepáticas. Para avaliação da qualidade de vida foi usada a versão abreviada do questionário da Organização Mundial da Saúde (WHOQOL-bref). Os sintomas da menopausa foram avaliados através do Menopause Rating Scale (MRS). A análise estatística foi realizada através dos testes t de Student, Mann-Whitney e ANOVA. As correlações entre o MRS e o WHOQOL-bref foram realizadas através de coeficientes de correlação. RESULTADOS: A idade média das mulheres incluídas no estudo foi de 52,2 (±10,4) anos e o tempo médio desde a realização do transplante foi de 6,1 (±3,3) anos. As mulheres transplantadas hepáticas tiveram melhores escores de qualidade de vida no domínio relacionado ao meio ambiente (p=0,01). Não houve diferença entre os dois grupos em nenhum domínio do MRS. As mulheres no grupo de comparação tiveram uma correlação fortemente negativa entre os sintomas somáticos do MRS e o domínio físico do WHOQOL-bref (p<0,01; r=-0,8), diferentemente das mulheres com transplante de fígado que tiveram uma correlação apenas moderada (p<0,01; r=-0,5). CONCLUSÕES: As mulheres com transplante de fígado tiveram melhores escores de qualidade de vida no domínio relacionado ao meio ambiente e não tiveram sintomas climatéricos mais intensos. Os sintomas do climatério influenciaram negativamente a qualidade de vida nas transplantadas hepáticas, porém com menor intensidade do que nas mulheres sem antecedentes de doença hepática.103110Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP

Factors associated with the onset of hypertension in women of 50 years of age or more in a city in southeastern Brazil

To evaluate factors associated with hypertension in Brazilian women of 50 years of age or more. A cross-sectional population based study using self-reports. A total of 622 women were included. The association between sociodemographic, clinical and behavioral factors and the woman's age at the onset of hypertension was evaluated. Data were analyzed according to cumulative continuation rates without hypertension, using the life-table method and considering annual intervals. Next, a Cox multiple regression analysis model was adjusted to analyze the occurrence rates of hypertension according to various predictor variables. Significance level was pre-established at 5% (95% confidence level) and the sampling plan (primary sampling unit) was taken into consideration. Median age at onset of hypertension was 64.3 years. Cumulative continuation rate without hypertension at 90 years was 20%. Higher body mass index (BMI) at 20-30 years of age was associated with a higher cumulative occurrence rate of hypertension over time (coefficient=0.078; p15 cigarettes/day was associated with a higher rate over time (coefficient=0.485; p=0.004). The results of the present study highlight the importance of weight control in young adulthood and of avoiding smoking in preventing hypertension in women aged ≥50 years.To evaluate factors associated with hypertension in Brazilian women of 50 years of age or more. A cross-sectional population based study using self-reports. A total of 622 women were included. The association between sociodemographic, clinical and beha3610467472FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO04/10524-

Quality Of Life And Menopausal Symptoms In Women With Liver Transplants.

To assess quality of life and climacteric symptoms in women with and without liver transplants. This was a cross-sectional study of 52 women undergoing follow-up at a university hospital in southeastern Brazil from February 4th, 2009 to January 5th, 2011. Twenty-four of these women were 35 years old or older and had undergone liver transplantation at least one year before study entry. The remaining 28 women had no liver disease and were matched by age and menstrual patterns to the patients with transplants. The abbreviated version of the World Health Organization (WHOQOL-BREF) questionnaire was used to assess quality of life. Menopausal symptoms were assessed using the Menopause Rating Scale (MRS). Statistical analysis was carried out by Student's t-test, Mann-Whitney test and analysis of variance. Correlations between MRS and the WHOQOL-BREF were established by correlation coefficients. The mean age of the women included in the study was 52.2 (± 10.4) years and the mean time since transplantation was 6.1 (± 3.3) years. Women with liver transplants had better quality of life scores in the environment domain (p=0.01). No difference was noted between the two groups in any domain of the MRS. For women in the comparison group, there was a strongly negative correlation between somatic symptoms in the MRS and the physical domain of the WHOQOL-BREF (p<0.01; r=-0.8). In contrast, there was only a moderate association for women with liver transplants (p<0.01; r=-0.5). Women with liver transplants had better quality of life scores in the domain related to environment and did not exhibit more intense climacteric symptoms than did those with no liver disease. Climacteric symptoms negatively influenced quality of life in liver transplant recipients, although less intensely than in women without a history of liver disease.35103-1

The effect of soy dietary supplement and low dose of hormone therapy on main cardiovascular health biomarkers: a randomized controlled trial

To assess the effects of a soy dietary supplement on the main biomarkers of cardiovascular health in postmenopausal women compared with the effects of low-dose hormone therapy (HT) and placebo. Double-blind, randomized and controlled intention-to-treat trial. Sixty healthy postmenopausal women, aged 40-60 years, 4.1 years mean time since menopause were recruited and randomly assigned to 3 groups: a soy dietary supplement group (isoflavone 90mg), a low-dose HT group (estradiol 1 mg plus noretisterone 0.5 mg) and a placebo group. Lipid profile, glucose level, body mass index, blood pressure and abdominal/hip ratio were evaluated in all the participants at baseline and after 16 weeks. Statistical analyses were performed using the χ2 test, Fisher's exact test, Kruskal-Wallis non-parametric test, analysis of variance (ANOVA), paired Student's t-test and Wilcoxon test. After a 16-week intervention period, total cholesterol decreased 11.3% and LDL-cholesterol decreased 18.6% in the HT group, but both did not change in the soy dietary supplement and placebo groups. Values for triglycerides, HDL-cholesterol, glucose level, body mass index, blood pressure and abdominal/hip ratio did not change over time in any of the three groups. The use of dietary soy supplement did not show any significant favorable effect on cardiovascular health biomarkers compared with HT. The trial is registered at the Brazilian Clinical Trials Registry (Registro Brasileiro de Ensaios Clínicos - ReBEC), number RBR-76mm75.To assess the effects of a soy dietary supplement on the main biomarkers of cardiovascular health in postmenopausalwomen compared with the effects of low-dose hormone therapy (HT) and placebo. Double-blind, randomizedand controlled intention-to-treat36251258FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO03/04464-

Autopercepção de vida sexual e fatores associados: estudo populacional em mulheres com 50 anos ou mais

PURPOSE: To evaluate the prevalence of women aged 50 years or more who are sexually active and their self-perception with respect to their sexual lives. Associated factors were also assessed. METHODS: A cross-sectional, population-based, self-reported household survey involving 622 Brazilian women aged 50 years or more. Sociodemographic, clinical, and behavioral factors were evaluated. The sexual life self-perception was classified as very good, good, fair, poor, or very poor. Data were analyzed using the &#967;² test, Fisher's exact test, and Poisson multiple regression analysis. Prevalence ratios and their 95% confidence intervals were also calculated. RESULTS: Of the women in this sample, 228 (36.7%) reported having a sexual life and, of these, 53.5% classified it as very good or good, while 46.5% considered it fair, poor, or very poor. The bivariate analysis indicated that being postmenopausal (p=0.025) and using natural remedies to treat the menopause (p=0.035) were factors associated with the woman classifying their sexual lives as fair, poor, or very poor. Multiple regression analysis showed that more women who had used or were currently using natural remedies for the menopause scored their sexual lives as fair, poor, or very poor. CONCLUSIONS: More than half the women aged 50 years or more in this study were not sexually active. A poorer sexual life self-perception was associated with the use of natural remedies to treat menopausal symptoms. This may indicate a need to improve the way in which these women are evaluated and treated. Women's assessment of their own sexual lives may prove a useful tool in clinical practice.OBJETIVO: Avaliar a prevalência de vida sexual em mulheres de 50 anos de idade ou mais, assim como avaliar sua autopercepção em relação à vida sexual e os fatores associados. MÉTODOS: Estudo transversal de base-populacional, por meio de autorrelato em pesquisa domiciliar, envolvendo 622 mulheres brasileiras de 50 anos de idade ou mais. Fatores sociodemográficos, clínicos e comportamentais foram avaliados. A autopercepção da vida sexual foi classificada como muito boa, boa, regular, ruim ou muito ruim. Os dados foram analisados usando-se o teste do &#967;², o teste exato de Fisher e a análise de regressão múltipla de Poisson. As razões de prevalência e seus intervalos de confiança de 95% foram calculados. RESULTADOS: Das mulheres nesta amostra, 228 (36,7%) relataram ter vida sexual e, destas, 53,5% classificaram-na como muito boa ou boa, enquanto 46,5% consideraram-na regular, ruim ou muito ruim. A análise bivariada indicou que estar na pós-menopausa (p=0,025) e usar remédios naturais para tratamento da menopausa (p=0,035) foram os fatores associados com a classificação da vida sexual pelas mulheres como regular, ruim ou muito ruim. A análise de regressão múltipla mostrou que mulheres que tinham usado ou usavam atualmente remédios naturais para o tratamento da menopausa classificaram sua vida sexual como regular, ruim ou muito ruim. CONCLUSÕES: Mais da metade das mulheres de 50 anos de idade ou mais não referiram vida sexual. Uma pior autopercepção da vida sexual foi associada com o uso de remédios naturais para o tratamento da menopausa. Isso pode indicar a necessidade de melhorias na avaliação e no tratamento dessas mulheres. Pode ser útil na prática clínica a autoavaliação da vida sexual pelas mulheres.29530

Age-related gastrointestinal alterations affect adipolysis induced by dairy and hybrid high-protein yogurts in differentiated 3T3-L1 adipocytes

info:eu-repo/semantics/publishedVersio

Risco cardiovascular em mulheres de meia-idade com câncer de mama: uma comparação entre dois modelos de risco

PURPOSE:It was to assess the risk of cardiovascular disease (CVD) in breast cancer survivors (BCS).METHODS:This cross-sectional study analyzed 67 BCS, aged 45 -65 years, who underwent complete oncological treatment, but had not received hormone therapy, tamoxifen or aromatase inhibitors during the previous 6 months. Lipid profile and CVD risk were evaluated, the latter using the Framingham and Systematic COronary Risk Evaluation (SCORE) models. The agreement between cardiovascular risk models was analyzed by calculating a kappa coefficient and its 95% confidence interval (CI).RESULTS:Mean subject age was 53.2&#177;6.0 years, with rates of obesity, hypertension, and dyslipidemia of 25, 34 and 90%, respectively. The most frequent lipid abnormalities were high total cholesterol (70%), high LDL-C (51%) and high non-HDL-C (48%) concentrations. Based on the Framingham score, 22% of the participants had a high risk for coronary artery disease. According to the SCORE model, 100 and 93% of the participants were at low risk for fatal CVD in populations at low and high risk, respectively, for CVD. The agreement between the Framingham and SCORE risk models was poor (kappa: 0.1; 95%CI 0.01 -0.2) for populations at high risk for CVD.CONCLUSIONS:These findings indicate the need to include lipid profile and CVD risk assessment in the follow-up of BCS, focusing on adequate control of serum lipid concentrations.OBJETIVO:Avaliar o risco de doença cardiovascular (DCV) em mulheres com câncer de mama.MÉTODOS:Foi conduzido estudo de corte transversal, com 67 mulheres com câncer de mama, entre 45 e 65 anos, tratamento oncológico completo, não usuárias de terapia hormonal, tamoxifeno ou inibidores da aromatase nos últimos 6 meses. Foram avaliados o perfil lipídico e o risco de DCV. Para avaliar o risco de DCV, foram utilizados os modelos Framingham e Systematic COronary Risk Evaluation (SCORE). Para investigar a concordância entre os modelos de risco cardiovascular, foi calculado o coeficiente kappa com seu respectivo intervalo de confiança (IC) de 95%.RESULTADOS:A média de idade das participantes foi de 53,2±6,0 anos. A prevalência de obesidade, hipertensão e dislipidemia foi 25, 34 e 90%, respectivamente. A prevalência de dislipidemia foi 90%. As anormalidades mais comuns do perfil lipídico foram: alto colesterol total (70%), alto LDL-C (51%) e alto não HDL-C (48%). Baseado no escore de Framingham, 22% das mulheres com câncer de mama apresentaram alto risco de doença arterial coronariana. De acordo com o modelo SCORE, 100 e 93% das participantes apresentaram baixo risco de DCV fatal, considerando populações de baixo e alto risco de DCV, respectivamente. A concordância entre os modelos de Framingham e SCORE foi ruim (kappa: 0,1; IC95% 0,01 -0,2), considerando populações de alto risco de DCV.CONCLUSÕES:Esses dados indicam a necessidade de incluir a avaliação do perfil lipídico e do risco de DCV na rotina de seguimento de mulheres com câncer de mama, sendo observadoo adequado controle dos níveis séricos de lipídios.15716