Tratamiento de úlceras venosas de piernas : revisión bibliográfica

Fil: Vidal, Jorgelina Natalí. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de DermatologíaFil: Cippitelli, María José. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de Dermatologí

Determination of cytokeratins 1, 13 and 14 in oral lichen planus

Introduccion: Cytokeratins (CK) are molecules of the cytoskeleton that contribute to the cellular differenciation. We studied the expression of CK1, CK13 and CK14 in thirty-three patients with OLP. The biopsied lesions were located in the dorsal surface of the tongue, the palatal keratinized mucosa and the nonkeratinized buccal mucosa. Objectives: This study aimed to determine the expression of CK1, CK13 and CK14 in oral lichen planus (OLP) and its relations with: clinical patterns, prognosis, drugs and tobacco intake and histopathological features. Study Design: Immunohistochemical analysis, retrospective, descriptive, observational and no randomized study. Results: No significant difference was observed in the expression of CK1 in patients with or without drug treat - ment. No association was found with the amount of drugs intake or smoking nor with the histopathological fea - tures examined. Samples immunostained with CK13 were all positive in the suprabasal layers, and 13 of them in the basal layer. In these last ones, statistical analysis showed significance in the grade of vacuolization of the basal layer ( p =0.023) and in the degree of exocytosis ( p =0.0025), this, making the degree of affection higher for both parameters. Thirty-two tissue sections were immunostained with CK14. CK14 was expressed in the basal layer in 97% of samples and in the suprabasal layer in 94% of samples. Conclusions: The three CK were altered in OLP. CK1 does not have a direct connection with the presence of or - thokeratosis. The finding of the CK13 in the basal layer is related to the agression of the lymphocytic infiltration in the epithelium, due to the basal stratum vacuolization and the increase in lymphocytic exocitosis. The presence of CK14 in the suprabasal stratums is not a parameter to predict malignancy. The CK in OLP do not follow the normal pattern of keratinized or non-keratinized mucosa

Secondary syphilis : manifestations in oral mucosa

La sífilis es una enfermedad infecciosa producida por una bacteria denominada Treponema pallidum. Su principal vía de transmisión es a través del contacto sexual. Actualmente se la considera un problema de salud pública por su creciente incidencia. Las manifestaciones en la mucosa oral pueden verse en diversas etapas de la enfermedad. A continuación se presentan dos casos clínicos de pacientes con lesiones orales de sífilis secundaria y un resumen de dicha patología.Syphilis is an infectious disease caused by the bacterium Treponema pallidum. It is mainly sexuallytransmitted. Actually it is considered a public health problem due to its growing incidence. Oral manifestations may occur in all stages simulating other diseases. Two cases of patients with oral lesions as a manifestation of secondary syphilis are reported and a review of the literature is presented in this article.Fil: Cantú Parra, Laura. Hospital Luis Lagomaggiore (Mendoza, Argentina)Fil: Vidal, Jorgelina Natalí. Hospital Luis Lagomaggiore (Mendoza, Argentina)Fil: Cippitelli, María José. Hospital Luis Lagomaggiore (Mendoza, Argentina)Fil: Rivarola de Gutiérrez, Emilce. Hospital Luis Lagomaggiore (Mendoza, Argentina

Síndrome de Wells : reporte de un caso

El Síndrome de Wells o celulitis eosinofílica, es una dermatosis infrecuente de etiología desconocida. Se lo clasifica dentro de las enfermedades eosinofílicas, ya que presentan en la histopatología infiltración por dichas células. Se han reportado casos asociados a múltiples entidades, como infecciones, neoplasias y fármacos. Clínicamente se manifiesta con pápulas y placas eritematosas, de bordes definidos. La mayoría evidencia una buena respuesta al tratamiento con corticoides sistémicos y puede evolucionar con períodos de brotes y remisiones.Wells syndrome, also known as eosinophilic cellulitis, is a rare dermatosis of unknown etiology. It belongs to the eosinophilic skin diseases, characterized by an eosinophil-rich infiltrate in histopathology. Most cases have been reported associated with multiple entities, such as infections, neoplasms and drugs. Typical findings include infiltrated erythematous papules and plaques. Most patients benefit from systemic corticosteroid therapy and can evolve with alternating periods of flares and remissions.Fil: Arzalluz, Gabriela. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de DermatologíaFil: Camardella, Ileana Rosalía. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de DermatologíaFil: Boulet, María Julia. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de DermatologíaFil: Cantú Parra, Laura. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de DermatologíaFil: Cippitelli, María José. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de DermatologíaFil: Innocenti Badano, Alicia Carolina. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de Dermatologí