945 research outputs found

    Improving Mechanical Ventilator Clinical Decision Support Systems with A Machine Learning Classifier for Determining Ventilator Mode

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    Clinical decision support systems (CDSS) will play an in-creasing role in improving the quality of medical care for critically ill patients. However, due to limitations in current informatics infrastructure, CDSS do not always have com-plete information on state of supporting physiologic monitor-ing devices, which can limit the input data available to CDSS. This is especially true in the use case of mechanical ventilation (MV), where current CDSS have no knowledge of critical ventilation settings, such as ventilation mode. To enable MV CDSS to make accurate recommendations related to ventilator mode, we developed a highly performant ma-chine learning model that is able to perform per-breath clas-sification of 5 of the most widely used ventilation modes in the USA with an average F1-score of 97.52%. We also show how our approach makes methodologic improvements over previous work and that it is highly robust to missing data caused by software/sensor error

    The contribution of perceived firm marketing innovation initiatives to customer perceived value and loyalty: does switching experience really matter?

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    In recent years, perceived firm marketing innovation initiatives (PFMII) are increasingly considered as an important means to ensure customers' continued loyalty. Although customer perceived value is believed to be a potential mediator between PFMII and customer loyalty, much of the evidence to date remains anecdotal or speculative. Furthermore, there is a dearth of knowledge about how the effect of PFMII on customer value differs between switchers and non-switchers. To bridge this knowledge gap, we propose a conceptual framework linking PFMII to customer perceived value and loyalty, and develop hypotheses about the moderating role of switching experience in some of these linkages. Data were collected from Generation Y(18–34 years old) who subscribed to post-paid mobile internet plans. The results showed that both functional and monetary values mediated the relationship between PFMII and customer loyalty. However, there was no significant difference in the effect of PFMII on functional and monetary values between switchers and non-switchers. This research contributes to theory and practice by clarifying linkages between PFMII and customer loyalty by investigating the often widely neglected role of customer perceived value. In addition, this study successfully extended Sweeney and Soutar (2001) PERVAL model by incorporating PFMII as the key driver of customer perceived value

    Mechanism of paraquat resistance in crassocephalum crepidioides (Benth.) S. moore during immature stage

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    The mechanism of paraquat resistance in Crassocephalum crepidioides at the six-leaf stage was investigated. The extractable paraquat was not metabolized fly the leaf tissue in the resistant (R) and susceptible (S) biotypes. Therefore, differential metabolism does not appear to play a role in the mechanism of resistance. The S biotype absorbed 44% more 14Gparaquat than the R biotype. However, more than 98% of the absorbed 14G paraquat remained on the treated leaf of both biotypes. The difference in absorption had a negative correlation with the amount of epicuticular wax as well as the cuticle of leaf surfaces in both biotypes. The results of this study suggest that differential absorption may be a factor that accounts for resistance to paraquat at the six-leaf stage
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