Wind Tunnel Seven-Hole Pressure Probe Calibration

The project studies and performs the calibration of a miniature seven-hole pressure probe designed to be utilized in the new wind tunnel of the Embry-Riddle Research Park. The seven-hole pressure probe is to measure flow angularity, which has better sensivity than conventional five-hole pressure probe. However, the seven-hole probe requires calibration due to manufacturing tolerance and its small dimensions. The seven-hole pressure probe is attached to a rotary table allowing the probe to change its pitch and yaw angle within the wind tunnel test section. Data is gathered from combinations of pitch and yaw angles between -10 to 10 degrees, with a step of 0.5 degree. Data gathered in initial wind tunnel tests were utilized for zero-angle offset correction for both pith and yaw angle. A time-series samples were recorded to determine how long the flow settles once pitch and yaw angle is altered. Calibration was then done with polynomial curve fit on MATLAB. An application of the wind tunnel test will also be performed to validate the calibration coefficients. A multiple 7-hole sensor rake also will be proposed which can be used to efficiently scan a large-scale wind tunnel test section, such as the new low-speed wind tunnel at the research park

Europe Research Trip

This project is a Research trip that will give a group of 16 Embry-Riddle students the opportunity to gain a different perspective of the Aviation industry. This experience will encourage students to learn and analyze different points of view to successfully answer the following questions: What impact does the economic system of European countries, such as Germany and France, have on the development of an aviation company, for instance Airbus and Lufthansa, compared to the aviation companies in the US? Do students learn more from a real life experience than from listening to a lecture? The project is composed of a visit to major aviation companies, such as Airbus, Lufthansa, and Condor Flugdienst, in two different cities: Toulouse in France and Frankfurt in Germany, with the idea to have real-world exposure and be able to compare different viewpoints, expectations, and future projects. This trip will also show our student body that anything is possible if there is dedication and effort and that real life experience outside a lecture in a classroom is very important in a student’s education. To prove this last point, a survey will be used to measure learning during the trip. Students travelling will be tested before and after the trip and results will be compared to see how beneficial are these trips

Brazil Research Trip: Evaluating the success of Embraer and aviation industry in Brazil

The project is a research trip to Brazil with 9 Embry-Riddle Aeronautical University students during Spring Break 2018. The group evaluated the success of aviation and aerospace industry in Brazil through multiple company visits during the trip. The group visited Embraer S.A for an aircraft factory tour, GOL Transportes Aéreos for airline operations tour, and São Paulo – Guarulhos International Airport for an airport management tour. Through these company and facilities visits, the group examined what conditions in Brazil allowed companies like Embraer S.A to become the third largest airframe manufacturer in the world, such as society, economy, and politics of Brazil. The research also includes a group of students conducting a same research while staying in Daytona Beach. Both the travelling group to Brazil and Daytona group will be evaluated with a written exam to demonstrate whether travelling produces a better result. The research exposes students to a different perspective of aviation and aerospace industry and promotes globalization on campus through travelling

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Characterization of the genetic landscape of Alzheimer’s disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/‘proxy’ AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Characterization of the genetic landscape of Alzheimer’s disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/‘proxy’ AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele