420 research outputs found

    Role of the Dental Community in HPV Vaccination Promotion

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    Introduction. With increasing awareness that human papillomavirus (HPV) can cause oropharyngeal cancer (OPC), dental providers may play an important role in promoting HPV vaccination and preventing cancer. Our goal was to assess knowledge and current HPV vaccine counseling practices among Vermont dentists and dental hygienists to identify potential targets for state-level interventions to increase vaccine coverage. Methods. We developed a survey to assess knowledge, beliefs, practices and barriers regarding HPV vaccination, and distributed it via email to practicing Vermont dentists and dental hygienists. Free responses were analyzed using a coding framework generated from three key informant interviews. Results. 90% of providers believe it is important for them to play an “active role” in their patients’ general medical care, yet only 50% believe it is their responsibility to recommend HPV vaccine. Only 50% feel knowledgeable enough to recommend the vaccine. 78.6% of providers rarely discuss HPV vaccination with their age-appropriate patients, and 82% rarely recommend the vaccine. When asked to name the biggest barrier against recommending vaccination, providers named the following factors most frequently: “not responsibility of dental provider” (27%); lack of confidence in knowledge (19%); time constraints (14%); and parent philosophical/religious opposition (11%). Discussion. Because dentists and dental hygienists care for a broad pediatric population across the state, dental communities may be poised to play an expanded role in Vermont’s efforts to improve its HPV vaccination coverage. Our study identifies several potential areas for provider-focused interventions, which include educating providers about the HPV vaccine and reducing significant barriers against recommending.https://scholarworks.uvm.edu/comphp_gallery/1266/thumbnail.jp

    A Geospatial Recipe for Identifying Social Values and Fragmentation Issues of the Friends of the Dunes Land Trust

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    The beach and coastal sand dunes comprise a dynamic and fragile ecosystem that provides a bounty of ecological services. These lands provide protection from coastal erosion and sea level rise, and are home to a rich biodiversity of plant and animal species in addition to their recreational value. The Humboldt Coastal Nature Center and the surrounding coastal dunes (HCNC) are man-aged as a land trust by Friends of the Dunes (FOD). FOD prioritize the restoration of dune habitats and encourages public involvement through community supported education and stewardship programs, guided nature tours, and naturalist training programs. The faculty, students, and staff of Humboldt State University regularly collaborate with FOD for research and volunteer programs. For example, mapping of the coastal dune habitats was performed in 2016, 2017 and 2018 by students from the intermediate remote sensing class and produced results addressing research gaps on social trails, dune movement, sea level rise, and invasive species distribution. This paper examines the natural and anthropocentric changes to the dune habitat from a geospatial perspective and identifies the social values of visitors to the dunes using HCNC visitor records. A small Unmanned Aerial Vehicle (sUAV) was used to acquire high-resolution imagery and then an orthomosaic image with 14 cm spatial resolution was created using the Structure from Motion (SfM) technique within the software Agisoft PhotoScan. sUAV imagery and existing maps were used to digitize social trails and distinguish them from official trails. Coastline change and dune movement were determined us-ing UAV imagery, NAIP satellite imagery, and lidar data. Visitor records of the HCNC were analysed using word clouds and line charts. The results showed that many of the social trails emerged from the neighborhoods southeast of the FOD land trust. As an observation, some directional signs for public access trails pointed out from the trail and may have caused confusion to visitors and mis-guided them into creating social trails. The social trails have disturbed nesting colonies of bees and led to trampling of dune mat habitats and rare plant communities. A word cloud created from visitor logs depicted that visitors had wonderful experiences at the coastal dunes and beach and highly support the conservation efforts underway. In conclusion, we believe these findings can be used as baseline information to help inform management techniques in order to better fit the region of interest and support the mission of the Friends of the Dunes land trust

    Spontaneous Intake and Long-Term Effects of Essential Oils After a Negative Postnatal Experience in Chicks

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    The postnatal period is critical for broiler chicks as they are exposed to potentially stressful environmental changes in the hatchery and during transportation to the rearing houses. The ability of broiler chicks to spontaneously drink essential oils (EO) to mitigate the effects of a negative postnatal experience was tested. Chicks were placed in the rearing facility either immediately (C group), or after a 24 h-delay period (D group) to mimic a delay in transportation possible under commercial conditions. In experiment 1, each group had access to either water only or to water and one EO (cardamom, marjoram, or verbena) from D1 to D13. Verbena EO intake was higher in the D group than in the C group from D1 to D6 and cardamom EO intake was lower in the D group than in the C group from D6 to D13. In experiment 2, half of the groups had access to water only and the other half had both water and the three EO simultaneously. Chicks from D and C groups chose the EO similarly except for cardamom EO with a lower intake being observed in the D than in the C group from D6 to D12. The delayed placement of the D group reduced chicken growth until 34 days of age and temporarily increased the feed conversion ratio, but did not affect their welfare or the prevalence of health disorders. The EO intake did not mitigate the growth reduction in D group chicks, but did mitigate the reduced Pectoralis major muscle yield. In conclusion, chicks were able to make spontaneous choices regarding EO intake according to their postnatal experience when EO were presented individually, but not when presented simultaneously as in our experimental design. The EO intake only partially mitigated the decrease in chicken performance after the negative postnatal experience

    Spontaneous intake of essential oils after a negative postnatal experience has long-term effects on blood transcriptome in chickens

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    Chicks subjected to early stressful factors could develop long-lasting effects on their performances, welfare and health. Free access to essential oils (EO) in poultry farming could mitigate these effects and potentially reduce use of antimicrobial drugs. This study on chicken analyzed long-lasting effects of post-hatch adverse conditions (Delayed group), and the impact of EO intake on blood physiological parameters and transcriptome. Half of the Control and Delayed groups had free access to EO, while the other half had only water for the first 13 days post-hatching. Blood analyses of metabolites, inflammation and oxidative stress biomarkers, and mRNA expression showed sex differences. Long-lasting effects of postnatal experience and EO intake persisted in blood transcriptome at D34. The early adverse conditions modified 68 genes in males and 83 genes in females. In Delayed males six transcription factors were over-represented (NFE2L2, MEF2A, FOXI1, Foxd3, Sox2 and TEAD1). In females only one factor was over-represented (PLAG1) and four under-represented (NFIL3, Foxd3, ESR2 and TAL

    The stroke oxygen pilot study: a randomized control trial of the effects of routine oxygen supplementation early after acute stroke--effect on key outcomes at six months

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    Introduction: Post-stroke hypoxia is common, and may adversely affect outcome. We have recently shown that oxygen supplementation may improve early neurological recovery. Here, we report the six-month outcomes of this pilot study. Methods: Patients with a clinical diagnosis of acute stroke were randomized within 24 h of admission to oxygen supplementation at 2 or 3 L/min for 72 h or to control treatment (room air). Outcomes (see below) were assessed by postal questionnaire at 6 months. Analysis was by intention-to-treat, and statistical significance was set at p#0.05. Results: Out of 301 patients randomized two refused/withdrew consent and 289 (148 in the oxygen and 141 in the control group) were included in the analysis: males 44%, 51%; mean (SD) age 73 (12), 71 (12); median (IQR) National Institutes of Health Stroke Scale score 6 (3, 10), 5 (3, 10) for the two groups respectively. At six months 22 (15%) patients in the oxygen group and 20 (14%) in the control group had died; mean survival in both groups was 162 days (p= 0.99). Median (IQR) scores for the primary outcome, the modified Rankin Scale, were 3 (1, 5) and 3 (1, 4) for the oxygen and control groups respectively. The covariate-adjusted odds ratio was 1.04 (95% CI 0.67, 1.60), indicating that the odds of a lower (i.e. better) score were non-significantly higher in the oxygen group (p= 0.86). The mean differences in the ability to perform basic (Barthel Index) and extended activities of daily living (NEADL), and quality of life (EuroQol) were also non-significant. Conclusions: None of the key outcomes differed at 6 months between the groups. Although not statistically significant and generally of small magnitude, the effects were predominantly in favour of the oxygen group; a larger trial, powered to show differences in longer-term functional outcomes, is now on-going. Trial Registration: Controlled-Trials.com ISRCTN12362720; Eudract.ema.europa.eu 2004-001866-4
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