1,435 research outputs found
Queering the archive - making friends and making zines: Applying queery theory to archive collections
The Queering the Archives (QTA) project was established to encourage a deep dive into CCCU's archival collections through a queer lens, exploring archival gaps and silences, and challenging the dominant power narratives that have informed archival practices
Iso-singlet Down Quark Mixing And CP Violation Experiments
We confront the new physics models with extra iso-singlet down quarks in the
new CP violation experimental era with and
measurements, events, and
limits. The closeness of the new experimental results to the standard
model theory requires us to include full SM amplitudes in the analysis. In
models allowing mixing to a new isosinglet down quark, as in E, flavor
changing neutral currents are induced that allow a mediated contribution
to mixing and which bring in new phases. In ,
, and plots we still find much
larger regions in the four down quark model than in the SM, reaching down to
, , , and down to zero, all at 1. We elucidate
the nature of the cancellation in an order four down quark mixing
matrix element which satisfies the experiments and reduces the number of
independent angles and phases. We also evaluate tests of unitarity for the
CKM submatrix.Comment: 14 pages, 16 figures, REVTeX
Permeability of Twenty-Two Small Diameter Hardwoods Growing on Southern Pine Sites
Gas permeability of hardwoods growing on southern pine sites is significantly affected by moisture content in the longitudinal direction. The ratio of permeability in the transverse to longitudinal directions is from 12,000:1 for post oak to over 1,000,000:1 for other oaks, but it is not affected by moisture. Although variation in longitudinal permeability varies greatly between and among species, for most species there was no height effect. A significant difference was detected between sapwood and corewood only in the longitudinal direction. Gas permeability tended to be somewhat less than liquid permeability
The Full Range of Predictions for B Physics From Iso-singlet Down Quark Mixing
We extend the range of predictions of the isosinglet (or vector) down quark
model to the fully allowed physical ranges, and also update this with the
effect of new physics constraints. We constrain the present allowed ranges of
sin(2*beta) and sin(2*alpha), gamma, x_s, and A_{B_s}. In models allowing
mixing to a new isosinglet down quark (as in E_6) flavor changing neutral
currents are induced that allow a Z^0 mediated contribution to B-Bbar mixing
and which bring in new phases. In (rho, eta), (x_s, sin(gamma)), and (x_s,
A_{B_s}) plots for the extra isosinglet down quark model which are herein
extended to the full physical range, we find new allowed regions that will
require experiments on sin(gamma) and/or x_s to verify or to rule out an extra
down quark contribution.Comment: 13 pages in RevTeX, 7 postscript figure
Linear Driving Force Model for Adsorption onto Activated Carbon Monolith
A mathematical model on carbon coated monolith using the linear driving force model is develop. The computer program is writted in MATLAB and simulation using data from [4] for cell density 200 cpsi was used to studies the effect of different variables on breakthrough profiles. The result showed that the breakthrough curve of the monolith is very sharp. Because of its an open structure and lower pressure drop, monolith is an attractive alternative internals for separation.Keywords: Adsorption, modeling, simulation, carbon coated monolith, breakthroug
NNT pseudoexon activation as a novel mechanism for disease in two siblings with familial glucocorticoid deficiency
CONTEXT:
Intronic DNA frequently encodes potential exonic sequences called pseudoexons. In recent years, mutations resulting in aberrant pseudoexon inclusion have been increasingly recognized to cause disease.
OBJECTIVES:
To find the genetic cause of familial glucocorticoid deficiency (FGD) in two siblings.
PATIENTS:
The proband and his affected sibling, from nonconsanguineous parents of East Asian and South African origin, were diagnosed with FGD at the ages of 21 and 8 months, respectively.
DESIGN:
Whole exome sequencing was performed on genomic DNA (gDNA) of the siblings. Variants in genes known to cause FGD were assessed for causality. Further analysis of gDNA and cDNA was performed by PCR/RT-PCR followed by automated Sanger sequencing.
RESULTS:
Whole exome sequencing identified a single, novel heterozygous variant (p.Arg71*) in nicotinamide nucleotide transhydrogenase (NNT) in both affected individuals. Follow-up cDNA analysis in the proband identified a 69-bp pseudoexon inclusion event, and Sanger sequencing of his gDNA identified a 4-bp duplication responsible for its activation. The variants segregated with the disease: p.Arg71* was inherited from the mother, the pseudoexon change was inherited from the father, and an unaffected sibling had inherited only the p.Arg71* variant.
CONCLUSIONS:
FGD in these siblings is caused by compound heterozygous mutations in NNT; one causing pseudoexon inclusion in combination with another leading to Arg71*. Discovery of this pseudoexon activation mutation highlights the importance of identifying sequence changes in introns by cDNA analysis. The clinical implications of these findings include: facilitation of antenatal genetic diagnosis, early institution of potentially lifesaving therapy, and the possibility of preventative or curative interventio
A spin-dependent local moment approach to the Anderson impurity model
We present an extension of the local moment approach to the Anderson impurity
model with spin-dependent hybridization. By employing the two-self-energy
description, as originally proposed by Logan and co-workers, we applied the
symmetry restoration condition for the case with spin-dependent hybridization.
Self-consistent ground states were determined through variational minimization
of the ground state energy. The results obtained with our spin-dependent local
moment approach applied to a quantum dot system coupled to ferromagnetic leads
are in good agreement with those obtained from previous work using numerical
renormalization group calculations
The SED Machine: a robotic spectrograph for fast transient classification
Current time domain facilities are finding several hundreds of transient
astronomical events a year. The discovery rate is expected to increase in the
future as soon as new surveys such as the Zwicky Transient Facility (ZTF) and
the Large Synoptic Sky Survey (LSST) come on line. At the present time, the
rate at which transients are classified is approximately one order or magnitude
lower than the discovery rate, leading to an increasing "follow-up drought".
Existing telescopes with moderate aperture can help address this deficit when
equipped with spectrographs optimized for spectral classification. Here, we
provide an overview of the design, operations and first results of the Spectral
Energy Distribution Machine (SEDM), operating on the Palomar 60-inch telescope
(P60). The instrument is optimized for classification and high observing
efficiency. It combines a low-resolution (R100) integral field unit (IFU)
spectrograph with "Rainbow Camera" (RC), a multi-band field acquisition camera
which also serves as multi-band (ugri) photometer. The SEDM was commissioned
during the operation of the intermediate Palomar Transient Factory (iPTF) and
has already proved lived up to its promise. The success of the SEDM
demonstrates the value of spectrographs optimized to spectral classification.
Introduction of similar spectrographs on existing telescopes will help
alleviate the follow-up drought and thereby accelerate the rate of discoveries.Comment: 21 pages, 20 figure
Long-term Periodicities of Cataclysmic Variables with Synoptic Surveys
A systematic study on the long-term periodicities of known Galactic
cataclysmic variables (CVs) was conducted. Among 1580 known CVs, 344 sources
were matched and extracted from the Palomar Transient Factory (PTF) data
repository. The PTF light curves were combined with the Catalina Real-Time
Transient Survey (CRTS) light curves and analyzed. Ten targets were found to
exhibit long-term periodic variability, which is not frequently observed in the
CV systems. These long-term variations are possibly caused by various
mechanisms, such as the precession of the accretion disk, hierarchical triple
star system, magnetic field change of the companion star, and other possible
mechanisms. We discuss the possible mechanisms in this study. If the long-term
period is less than several tens of days, the disk precession period scenario
is favored. However, the hierarchical triple star system or the variations in
magnetic field strengths are most likely the predominant mechanisms for longer
periods.Comment: 33 pages, 9 figures (manuscript form), Accepted for publication in
PAS
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