264 research outputs found
Original Effective, Safe Technique of Obtaining Platelet Rich Plasma by Centrifugation of the Blood Plasma in Modified Syringe Containers
The aim: to develop, substantiate an effective and safe technology for producing PRP (platelet rich plasma). To quantify the substrate based on the recommended centrifugation protocols.Materials and methods: the effectiveness of the original harvesting protocol was evaluated by quantifying the number of platelets. The proposed technique is formed basing on the basic principles of double centrifugation of whole blood in test tubes with anticoagulant, separation with the release of a plasma layer with a high content of platelets.The centrifuging mode for quantifying the effectiveness of the substrate was selected according to recommendations based on a study confirming maximum efficiency (160gΓ10min + 250gΓ15min).For quantitative evaluation, blood was collected from 10 healthy volunteers (7 men, 3 women) with an average age of 26.0Β±2.6, and centrifuged in standard mode. Quantitative evaluation of platelets of whole blood and the obtained PRP substrate was carried out with a semi-automatic analyzer.Results: the proposed technique is based on the use as a container for centrifuging a syringe with a LuerLock design, which is hermetically sealed with a congruent plug, adapted by the external size of the centrifuge rotor bowl. Phase selection after centrifugation was performed by aspiration of the syringe contents after centrifugation is performed through a three-way valve. The substrate was obtained by repeated centrifugation of the contents, which allows obtaining a variable volume and platelet concentration in PRP. The amount of platelets (PLT) of whole blood is 227.0Β±57.0 thousand per ml. PLT PRP 945.0Β±279.0 thousand per ml.Conclusions: the proposed method of separation of whole blood with the release of the platelet rich plasma demonstrates high efficiency, which corresponds to the level of increasing the number of platelets in reducing the volume at the level of the best ready-made solutions.The equipment is economical and does not require highly specialized equipment and consumables. The proposed technique provides a wide choice to the performer in the received volume of the substrate
Magnetic Resonance Imaging with Diffuse Weighted Imaging and Computed Tomography with Intravenous Contrast in Staging of Disseminated Ovarian, Stomach, Colorectal Cancer
The aim of the research. Development and implementation of new methods for pre-operative staging of advanced ovarian, gastric and colorectal cancer to improve patient selection for cytoreductive surgery and increase its radicality.Materials and methods. Data from 120 patients with advanced ovarian cancer, 28 with advanced gastric cancer and 119 with advanced colorectal cancer were analyzed. Preoperative detection of the incidence of peritoneal carcinoma and the possibility of surgery in radical or cytoreductive volume performed by CT with intravenous contrast (72 patients with ovarian cancer, 17 patients with gastric cancer, and 69 patients with colorectal cancer), and MR T1 and T2, contrast-enhanced T1, and diffuse-weighted sequences (48 patients with ovarian cancer, 11 patients with gastric cancer, and 50 patients with colorectal cancer). Subsequently, preoperative and intraoperative assessment of the prevalence of the tumour process with peritoneal carcinoma index (PCI) by Sugarbaker was performed.Results. A statistically significant increase in the informativeness of the preoperative assessment of the incidence of tumour process in peritoneum and the presence of distant metastases using DWI / MRI compared with CT with intravenous contrast was determined. Patients from all groups were categorized according to the completeness index of cytoreduction achieved by preoperative staging and patient selection using DWI / MRI and CT. The use of DWI / MRI allowed to significantly reduce the number of suboptimal and non-optimal cytoreductive interventions.Conclusions. DWI / MRI has made it possible to significantly improve the preoperative incidence of advanced ovarian, gastric, and colorectal cancer compared to CT, predict the radicality of future surgery, and detect inoperable cases
Original effective, safe technique of obtaining platelet rich plasma by centrifugation of the blood plasma in modified syringe containers
The aim: to develop, substantiate an effective and safe technology for producing PRP (platelet rich plasma). To quantify the substrate based on the recommended centrifugation protocols. The effectiveness of the original harvesting protocol was evaluated by quantifying the number of platelets. The proposed technique is formed basing on the basic principles of double centrifugation of whole blood in test tubes with anticoagulant, separation with the release of a plasma layer with a high content of platelets. The centrifuging mode for quantifying the effectiveness of the substrate was selected according to recommendations based on a study confrming maximum effciency (160 gΓ10 min + 250 gΓ15 min). For quantitative evaluation, blood was collected from 10 healthy volunteers (7 men, 3 women) with an average age of 26.0Β±2.6, and centrifuged in standard mode. Quantitative evaluation of platelets of whole blood and the obtained PRP substrate was carried out with a semi-automatic analyzer. The proposed technique is based on the use as a container for centrifuging a syringe with a LuerLock design, which is hermetically sealed with a congruent plug, adapted by the external size of the centrifuge rotor bowl. Phase selection after centrifugation was performed by aspiration of the syringe contents after centrifugation is performed through a three-way valve. The substrate was obtained by repeated centrifugation of the contents, which allows obtaining a variable volume and platelet concentration in PRP. The amount of platelets (PLT) of whole blood is 227.0Β±57.0 thousand per ml. PLT PRP 945.0Β±279.0 thousand per ml. The proposed method of separation of whole blood with the release of the platelet rich plasma demonstrates high effciency, which corresponds to the level of increasing the number of platelets in reducing the volume at the level of the best ready-made solutions. The equipment is economical and does not require highly specialized equipment and consumables. The proposed technique provides a wide choice to the performer in the received volume of the substrate
Evaluation of centrifuging regimes for the purpose of optimizing the platelet rich plasma harvesting protocol
Aim: Based on the classical principles, to determine the optimal conditions for centrifugation, PRP harvesing (platelet-rich plasma). To conduct a quantitative assessment of the substrate obtained under different conditions of centrifugation. Based on the basic principles of obtaining platelet-rich plasma (PRP) by centrifuging in containers with an anticoagulant followed by phase separation to obtain the fnal substrate, the effciency of the technique under the conditions of single and double centrifugation as well as under different conditions of acceleration and centrifugation was evaluated. Blood for follow-up was collected from 20 healthy volunteers (11 men, 9 women) average 25.3Β±4.1 in syringes of LuerLock design with ACD-A anticoagulant solution, and centrifuged. Centrifugation was carried out under controlled conditions using a centrifuge with rotating bowls of the rotor. Centrifugation was performed at an acceleration of 100β400 g in time intervals up to 20 minutes. Activation of the substrate was performed with calcium chloride solution. Quantitative evaluation of platelets of whole blood and the fnal substrate of PRP was carried out with a semi-automatic analyzer. The obtained results demonstrate the maximum level of harvesting effciency when performing double centrifugation in the 150g Γ 15 min+250g Γ 10 min mode. Subject to this centrifugation protocol, it is possible to obtain a substrate that complies with the standardized requirements for PRP. The maximum level of an increase in the number of platelets in the substrate in comparison with whole blood is determined at the level of Γ4.36 with concentration (volume reduction) Γ5 in comparison with the volume of whole blood. This study demonstrated the advantage of double centrifuging modes over single modes. According to the results of the study, it was possible to determine the conditions for an optimal double-centrifugation mode (acceleration and duration), which allows us to achieve the most effcient concentration of the substrate
ΠΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½Π½ΡΠΉ Π²ΡΠ±ΠΎΡ ΠΌΠ°Π»ΠΎΠΈΠ½Π²Π°Π·ΠΈΠ²Π½ΠΎΠ³ΠΎ Ρ ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π΄ΠΎΡΡΡΠΏΠ° Π² Ρ ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΌ Π»Π΅ΡΠ΅Π½ΠΈΠΈ ΠΆΠ΅Π»ΡΠ½ΠΎΠΊΠ°ΠΌΠ΅Π½Π½ΠΎΠΉ Π±ΠΎΠ»Π΅Π·Π½ΠΈ
In 2009 at the University Clinic of the Odessa National Medical University with minilaparoscopic and single-port technology we have operated 47 patients with cholelithiasis. 26 patients were performed minilaparoscopic cholecystectomy, 21 β laparoscopic cholecystectomy using a single laparoscopic access. All surgical interventions had no intraoperative complications. In 5 patients because of anatomic difficulties in removing the gallbladder, we were used to installing an additional trocar in the epigastric region. Time used for interventions ranged from 30 to 130 minutes. Patients were hospitalized after the surgery from 1 to 4 days. Technically, the performance of single-port laparoscopic cholecystectomy was more difficult than the traditional laparoscopic or minilaparoscopic operations due to lack of conditions for the quality triangulation, visualization of anatomical structures in the area of operation and the small angle between the operating instruments. Particular attention was devoted to adequate closure of the abdominal wall defect after installing the port. Pain after use minilaparoscopic surgery was significantly less than with traditional laparoscopic approach. The intensity of pain after single-port operations, was comparable with that of conventional traditional laparoscopy. At follow-up of patients during the first months after surgery separated complications were not observed, marked by a beautiful cosmetic effect. 8 months after surgery 1 patient was diagnosed trocar-site hernia after a single port laparoscopic cholecystectomy.Π‘ 2009 Π³. Π² ΠΊΠ»ΠΈΠ½ΠΈΠΊΠ΅ ΠΠ΄Π΅ΡΡΠΊΠΎΠ³ΠΎ Π½Π°ΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠ³ΠΎ ΡΠ½ΠΈΠ²Π΅ΡΡΠΈΡΠ΅ΡΠ° ΠΏΡΠΎΠΎΠΏΠ΅ΡΠΈΡΠΎΠ²Π°Π½ΠΎ 47 Π±ΠΎΠ»ΡΠ½ΡΡ
Ρ ΠΆΠ΅Π»ΡΠ½ΠΎΠΊΠ°ΠΌΠ΅Π½Π½ΠΎΠΉ Π±ΠΎΠ»Π΅Π·Π½ΡΡ. Π£ 26 Π±ΠΎΠ»ΡΠ½ΡΡ
Π²ΡΠΏΠΎΠ»Π½Π΅Π½Π° ΠΌΠΈΠ½ΠΈΠ»Π°ΠΏΠ°ΡΠΎΡΠΊΠΎΠΏΠΈΡΠ΅ΡΠΊΠ°Ρ Ρ
ΠΎΠ»Π΅ΡΠΈΡΡΡΠΊΡΠΎΠΌΠΈΡ, Ρ 21 β ΠΎΠ΄Π½ΠΎΠΏΠΎΡΡΠΎΠ²Π°Ρ. ΠΡΠ΅ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠ²Π½ΡΠ΅ Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ²Π° ΠΏΡΠΎΡΠ»ΠΈ Π±Π΅Π· ΠΈΠ½ΡΡΠ°ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΡΡ
ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ. Π£ 5 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² ΠΈΠ·-Π·Π° Π°Π½Π°ΡΠΎΠΌΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ»ΠΎΠΆΠ½ΠΎΡΡΠ΅ΠΉ ΠΌΡ Π²ΡΠ½ΡΠΆΠ΄Π΅Π½Ρ Π±ΡΠ»ΠΈ ΠΏΡΠΈΠ±Π΅Π³Π½ΡΡΡ ΠΊ ΡΡΡΠ°Π½ΠΎΠ²ΠΊΠ΅ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΠΎΠ°ΠΊΠ°ΡΠ° Π² ΡΠΏΠΈΠ³Π°ΡΡΡΠ°Π»ΡΠ½ΠΎΠΉ ΠΎΠ±Π»Π°ΡΡΠΈ. ΠΡΠ΅ΠΌΡ, ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½Π½ΠΎΠ΅ Π΄Π»Ρ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ², Π²Π°ΡΡΠΈΡΠΎΠ²Π°Π»ΠΎΡΡ ΠΎΡ 30 Π΄ΠΎ 130 ΠΌΠΈΠ½. ΠΠΎΠ»ΡΠ½ΡΠ΅ Π½Π°Ρ
ΠΎΠ΄ΠΈΠ»ΠΈΡΡ Π² ΡΡΠ°ΡΠΈΠΎΠ½Π°ΡΠ΅ ΠΎΡ 1 Π΄ΠΎ 4 ΡΡΡ. ΠΡΠΈ Π½Π°Π±Π»ΡΠ΄Π΅Π½ΠΈΠΈ Π·Π° ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ°ΠΌΠΈ Π² ΡΠ΅ΡΠ΅Π½ΠΈΠ΅ ΠΏΠ΅ΡΠ²ΡΡ
ΠΌΠ΅ΡΡΡΠ΅Π² ΠΏΠΎΡΠ»Π΅ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΈ ΠΎΡΠ΄Π°Π»Π΅Π½Π½ΡΡ
ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ Π½Π΅ Π½Π°Π±Π»ΡΠ΄Π°Π»ΠΎΡΡ, ΠΎΡΠΌΠ΅ΡΠ΅Π½ Ρ
ΠΎΡΠΎΡΠΈΠΉ ΠΊΠΎΡΠΌΠ΅ΡΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΡΡΠ΅ΠΊΡ.
Π‘ΠΏΡΡΡΡ 8 ΠΌΠ΅ΡΡΡΠ΅Π² ΠΏΠΎΡΠ»Π΅ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΈ Ρ 1 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ° ΠΏΠΎΡΠ»Π΅ ΠΎΠ΄Π½ΠΎΠΏΠΎΡΡΠΎΠ²ΠΎΠΉ Π»Π°ΠΏΠ°ΡΠΎΡΠΊΠΎΠΏΠΈΡΠ΅ΡΠΊΠΎΠΉ Ρ
ΠΎΠ»Π΅ΡΠΈΡΡΡΠΊΡΠΎΠΌΠΈΠΈ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΡΠΎΠ²Π°Π½Π° ΡΡΠΎΠ°ΠΊΠ°ΡΠ½Π°Ρ Π³ΡΡΠΆΠ° Π² ΠΌΠ΅ΡΡΠ΅ ΡΡΡΠ°Π½ΠΎΠ²ΠΊΠΈ ΠΏΠΎΡΡΠ°
Π¦ΠΈΡΠΎΡΠ΅Π΄ΡΠΊΡΠΈΠ²Π½Π° Ρ ΡΡΡΡΠ³ΡΡ ΠΏΡΠΈ Ρ ΡΠΌΡΠΎΡΠ΅Π·ΠΈΡΡΠ΅Π½ΡΠ½ΡΠΉ Π»Π΅ΠΉΠΎΠΌΡΠΎΡΠ°ΡΠΊΠΎΠΌΡ ΠΌΠ°ΡΠΊΠΈ
Π¦ΠΈΡΠΎΡΠ΅Π΄ΡΠΊΡΠΈΠ²Π½Π° Ρ
ΡΡΡΡΠ³ΡΡ ΠΏΡΠΈ Ρ
ΡΠΌΡΠΎΡΠ΅Π·ΠΈΡΡΠ΅Π½ΡΠ½ΡΠΉ Π»Π΅ΠΉΠΎΠΌΡΠΎΡΠ°ΡΠΊΠΎΠΌΡ ΠΌΠ°ΡΠΊ
ΠΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΠΎΠ±ΠΎΠ³Π°ΡΠ΅Π½Π½ΠΎΠΉ ΡΡΠΎΠΌΠ±ΠΎΡΠΈΡΠ°ΠΌΠΈ ΠΏΠ»Π°Π·ΠΌΡ Ρ ΡΠ΅Π»ΡΡ ΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΠΊΠΈ ΠΏΠΎΠ·Π΄Π½ΠΈΡ ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ ΠΈ Π±ΠΎΠ»Π΅Π²ΠΎΠ³ΠΎ ΡΠΈΠ½Π΄ΡΠΎΠΌΠ° ΠΏΠΎΡΠ»Π΅ Π³Π΅ΡΠ½ΠΈΠΎΠΏΠ»Π°ΡΡΠΈΠΊΠΈ
Π¦Π΅Π»Ρ. ΠΠ° ΡΡΠ΅Ρ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ ΠΎΠ±ΠΎΠ³Π°ΡΠ΅Π½Π½ΠΎΠΉ ΡΡΠΎΠΌΠ±ΠΎΡΠΈΡΠ°ΠΌΠΈ ΠΏΠ»Π°Π·ΠΌΡ (ΠTΠ) ΡΠ½ΠΈΠ·ΠΈΡΡ ΡΡΠ΅ΠΏΠ΅Π½Ρ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΡΡΠΈ ΠΏΠΎΠ·Π΄Π½ΠΈΡ
ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
, ΠΎΠΏΠ΅ΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΏΠΎ ΠΏΠΎΠ²ΠΎΠ΄Ρ ΠΈΠ½ΡΠΈΠ·ΠΈΠΎΠ½Π½ΡΡ
Π²Π΅Π½ΡΡΠ°Π»ΡΠ½ΡΡ
Π³ΡΡΠΆ.
ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. Π ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅, ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½Π½ΠΎΠ΅ Π² ΡΡΠ»ΠΎΠ²ΠΈΡΡ
Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΎΡΠ΄Π΅Π»Π΅Π½ΠΈΡ Π¦Π΅Π½ΡΡΠ° ΡΠ΅ΠΊΠΎΠ½ΡΡΡΡΠΊΡΠΈΠ²Π½ΠΎΠΉ ΠΈ Π²ΠΎΡΡΡΠ°Π½ΠΎΠ²ΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½Ρ (Π£Π½ΠΈΠ²Π΅ΡΡΠΈΡΠ΅ΡΡΠΊΠ°Ρ ΠΊΠ»ΠΈΠ½ΠΈΠΊΠ°) ΠΠ΄Π΅ΡΡΠΊΠΎΠ³ΠΎ Π½Π°ΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠ³ΠΎ ΡΠ½ΠΈΠ²Π΅ΡΡΠΈΡΠ΅ΡΠ° Ρ 2013 ΠΏΠΎ 2019 Π³., Π²ΠΊΠ»ΡΡΠ΅Π½Ρ 84 Π±ΠΎΠ»ΡΠ½ΡΡ
, ΠΎΠΏΠ΅ΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΏΠΎ ΠΏΠΎΠ²ΠΎΠ΄Ρ ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΡΡ
Π²Π΅Π½ΡΡΠ°Π»ΡΠ½ΡΡ
Π³ΡΡΠΆ. Π‘ΡΠ΅Π΄Π½ΠΈΠΉ Π²ΠΎΠ·ΡΠ°ΡΡ Π±ΠΎΠ»ΡΠ½ΡΡ
ΡΠΎΡΡΠ°Π²ΠΈΠ» (60,1 Β± 7,6) Π³ΠΎΠ΄Π°, ΡΠ°Π·ΠΌΠ΅Ρ Π³ΡΡΠΆΠ΅Π²ΡΡ
Π΄Π΅ΡΠ΅ΠΊΡΠΎΠ² - 8,2 ΡΠΌ, ΡΡΠ΅Π΄Π½ΠΈΠΉ ΠΈΠ½Π΄Π΅ΠΊΡ ΠΌΠ°ΡΡΡ ΡΠ΅Π»Π° β 31,8 ΠΊΠ³/ΠΌ2. ΠΠΎΠ»ΡΠ½ΡΠΌ ΠΏΠΎ ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΈΡΠΌ Π²ΡΠΏΠΎΠ»Π½Π΅Π½ ΡΡΠ°Π½Π΄Π°ΡΡΠ½ΡΠΉ ΠΎΠ±ΡΠ΅ΠΌ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠ²Π½ΠΎΠ³ΠΎ Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ²Π°: Π³ΡΡΠΆΠ΅ΡΠ΅ΡΠ΅Π½ΠΈΠ΅, Π³Π΅ΡΠ½ΠΈΠΎΠΏΠ»Π°ΡΡΠΈΠΊΠ° ΠΏΠ΅ΡΠ΅Π΄Π½Π΅ΠΉ Π±ΡΡΡΠ½ΠΎΠΉ ΡΡΠ΅Π½ΠΊΠΈ ΠΎΠ±Π»Π΅Π³ΡΠ΅Π½Π½ΡΠΌ (80 Π³/ΠΌ2) ΠΏΠΎΠ»ΠΈΠΏΡΠΎΠΏΠΈΠ»Π΅Π½ΠΎΠ²ΡΠΌ ΠΈΠΌΠΏΠ»Π°Π½ΡΠ°ΡΠΎΠΌ. ΠΠ°ΡΠΈΠ΅Π½ΡΠ°ΠΌ ΠΎΡΠ½ΠΎΠ²Π½ΠΎΠΉ Π³ΡΡΠΏΠΏΡ ΠΏΠΎΡΠ»Π΅ Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΈΡ ΠΏΠ»Π°ΡΡΠΈΠΊΠΈ Π·ΠΎΠ½Ρ ΠΈΠΌΠΏΠ»Π°Π½ΡΠ°ΡΠΈΠΈ ΠΏΡΠΎΡΠ΅Π·Π° ΠΈΠ½ΡΠΈΠ»ΡΡΡΠΈΡΠΎΠ²Π°Π»ΠΈ Π°ΠΊΡΠΈΠ²ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ Π°ΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ½ΠΎΠΉ ΠΠ’Π, ΠΊΠΎΡΠΎΡΠ°Ρ Π±ΡΠ»Π° Π·Π°Π³ΠΎΡΠΎΠ²Π»Π΅Π½Π° ΠΏΡΡΠ΅ΠΌ Π΄Π²ΠΎΠΉΠ½ΠΎΠ³ΠΎ ΡΠ΅Π½ΡΡΠΈΡΡΠ³ΠΈΡΠΎΠ²Π°Π½ΠΈΡ, Π² ΠΎΠ±ΡΠ΅ΠΌΠ΅ 14 β 38 ΠΌΠ». ΠΠ°ΡΠΈΠ΅Π½ΡΠ°ΠΌ ΠΊΠΎΠ½ΡΡΠΎΠ»ΡΠ½ΠΎΠΉ Π³ΡΡΠΏΠΏΡ ΠΈΠ½ΡΠΈΠ»ΡΡΡΠ°ΡΠΈΡ ΠΠ’Π Π½Π΅ Π²ΡΠΏΠΎΠ»Π½ΡΠ»ΠΈ. ΠΠ°ΡΠ΅ΡΡΠ²ΠΎ ΠΆΠΈΠ·Π½ΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² ΠΎΡΠ΅Π½ΠΈΠ²Π°Π»ΠΈ Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΡΡΠ°Π½Π΄Π°ΡΡΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΎΠΏΡΠΎΡΠ½ΠΈΠΊΠ° SF-36 Π΄ΠΎ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΈ, Π° ΡΠ°ΠΊΠΆΠ΅ Π² ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΌ ΠΏΠ΅ΡΠΈΠΎΠ΄Π΅. Π‘ ΡΠ΅Π»ΡΡ Π΄ΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π½Π΅ΠΉΡΠΎΠΏΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Π±ΠΎΠ»ΠΈ ΠΏΡΠΈΠΌΠ΅Π½ΡΠ»ΠΈ ΠΎΠΏΡΠΎΡΠ½ΠΈΠΊΠΈ DN4 ΠΈ ID Pain.
Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π£ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² ΠΎΠ±Π΅ΠΈΡ
Π³ΡΡΠΏΠΏ Π² ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΌ ΠΏΠ΅ΡΠΈΠΎΠ΄Π΅ ΠΎΡΠΌΠ΅ΡΠ°Π»ΠΈ ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΠ΅ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ ΠΊΠ°ΡΠ΅ΡΡΠ²Π° ΠΆΠΈΠ·Π½ΠΈ. Π‘ΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠ°Ρ Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎΡΡΡ ΡΠ°Π·Π»ΠΈΡΠΈΠΉ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ Π±ΡΠ»Π° Π²ΡΡΠ΅ Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ Π½Π°Π΄Π°ΠΏΠΎΠ½Π΅Π²ΡΠΎΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ΡΠ°ΡΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΠ΅ΠΌ ΠΏΡΠΎΡΠ΅Π·Π°. ΠΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ ΡΠΈΠ·ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π·Π΄ΠΎΡΠΎΠ²ΡΡ ΠΈ Π°ΡΡΠΎΡΠΈΠΈΡΠΎΠ²Π°Π½Π½ΡΠ΅ Ρ Π½ΠΈΠΌΠΈ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ ΡΠΎΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ, ΠΎΠ±ΡΠ΅Π³ΠΎ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ Π·Π΄ΠΎΡΠΎΠ²ΡΡ Π΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΠΎΠ²Π°Π»ΠΈ Π·Π½Π°ΡΠΈΠΌΠΎ Π±ΠΎΠ»Π΅Π΅ Π²ΡΡΠΎΠΊΠΈΠΉ ΡΡΠΎΠ²Π΅Π½Ρ ΠΊΠ°ΡΠ΅ΡΡΠ²Π° ΠΆΠΈΠ·Π½ΠΈ Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² ΠΎΡΠ½ΠΎΠ²Π½ΠΎΠΉ Π³ΡΡΠΏΠΏΡ. ΠΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Ρ ΠΎΠ±ΡΠ΅Π³ΠΎ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ Π·Π΄ΠΎΡΠΎΠ²ΡΡ Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΏΠΎΡΠ»Π΅ Π½Π°Π΄Π°ΠΏΠΎΠ½Π΅Π²ΡΠΎΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Π³Π΅ΡΠ½ΠΈΠΎΠΏΠ»Π°ΡΡΠΈΠΊΠΈ Ρ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ΠΌ ΠΠ’Π Π±ΡΠ» Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎ Π²ΡΡΠ΅, ΡΠ΅ΠΌ Π² ΠΊΠΎΠ½ΡΡΠΎΠ»ΡΠ½ΠΎΠΉ Π³ΡΡΠΏΠΏΠ΅ β ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²Π΅Π½Π½ΠΎ 69,3 Β± 3,8 ΠΈ 59,7 Β± 4,1 (p < 0,05).
ΠΡΠ²ΠΎΠ΄Ρ. Π’Π΅Ρ
Π½ΠΈΠΊΠ° ΠΈΠ½ΡΠΈΠ»ΡΡΡΠ°ΡΠΈΠΈ ΠΌΡΠ³ΠΊΠΈΡ
ΡΠΊΠ°Π½Π΅ΠΉ, ΠΊΠΎΠ½ΡΠ°ΠΊΡΠΈΡΡΡΡΠΈΡ
Ρ ΠΏΠΎΠ»ΠΈΠΏΡΠΎΠΏΠΈΠ»Π΅Π½ΠΎΠ²ΡΠΌ ΠΏΡΠΎΡΠ΅Π·ΠΎΠΌ, Π±Π΅Π·ΠΎΠΏΠ°ΡΠ½Π°, Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎ Π½Π΅ ΡΠ²Π΅Π»ΠΈΡΠΈΠ²Π°Π΅Ρ ΡΠΈΡΠΊ Π²ΠΎΠ·Π½ΠΈΠΊΠ½ΠΎΠ²Π΅Π½ΠΈΡ Π»ΠΎΠΊΠ°Π»ΡΠ½ΡΡ
ΠΈΠ»ΠΈ ΡΠΈΡΡΠ΅ΠΌΠ½ΡΡ
ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ. ΠΡΠ΅Π΄Π»ΠΎΠΆΠ΅Π½Π½Π°Ρ ΠΌΠ΅ΡΠΎΠ΄ΠΈΠΊΠ° Π·Π° ΡΡΠ΅Ρ ΠΌΠΎΠ΄ΠΈΡΠΈΠΊΠ°ΡΠΈΠΈ ΡΠ΅ΠΏΠ°ΡΠ°ΡΠΈΠ²Π½ΡΡ
ΠΏΡΠΎΡΠ΅ΡΡΠΎΠ² Π² Π·ΠΎΠ½Π΅ Π³Π΅ΡΠ½ΠΈΠΎΠΏΠ»Π°ΡΡΠΈΠΊΠΈ ΡΠΏΠΎΡΠΎΠ±ΡΡΠ²ΡΠ΅Ρ ΠΈΠ½ΡΠ΅Π³ΡΠ°ΡΠΈΠΈ ΠΏΡΠΎΡΠ΅Π·Π°, ΡΠ½ΠΈΠΆΠ°Π΅Ρ ΡΠΈΡΠΊ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΈ ΡΡΠ΅ΠΏΠ΅Π½Ρ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΡΡΠΈ Π±ΠΈΠΎΠΌΠ΅Ρ
Π°Π½ΠΈΡΠ΅ΡΠΊΠΈΡ
Π½Π°ΡΡΡΠ΅Π½ΠΈΠΉ, Ρ
ΡΠΎΠ½ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π±ΠΎΠ»Π΅Π²ΠΎΠ³ΠΎ ΡΠΈΠ½Π΄ΡΠΎΠΌΠ°, ΡΡΠΎ ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΠΎ ΡΠΊΠ°Π·ΡΠ²Π°Π΅ΡΡΡ Π½Π° ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΠΆΠΈΠ·Π½ΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ². ΠΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΡΠ΅Ρ
Π½ΠΈΠΊΠΈ ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈ Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎ Π²ΡΡΠ΅ Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² ΠΏΠΎΡΠ»Π΅ Π½Π°Π΄Π°ΠΏΠΎΠ½Π΅Π²ΡΠΎΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Π³Π΅ΡΠ½ΠΈΠΎΠΏΠ»Π°ΡΡΠΈΠΊΠΈ
- β¦