346 research outputs found

    Twitter as a Marketing Tool for Libraries

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    Libraries are using Twitter for a variety of communication purposes. Some libraries use it to listen to what their customers are saying about the library. Steven Bell states that Twitter is a “golden opportunity to connect with members of the library community.” (Bell, 2012) Some libraries use Twitter to make connections to people and organizations within their communities to build community online. (Gunton & Davis, 2012) Some libraries use Twitter to promote programs and services, including those of the library, but also those of other organizations. Twitter can be an excellent way to learn what your customers are thinking, to build conversations with your users, to address customer concerns, and to advocate for your programs and services

    Users 2.0: Technology at your service

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    It is exciting, as practicing librarians, to find a singular voice that stands out as a strong influence on the profession. Anne Grodzins Lipow provided one such voice, inspiring us to evaluate our philosophy of patron service and helping us define our professional values. Lipow’s body of work encompasses many contemporary library issues, involving myriad aspects of customer service. Lipow addressed issues including patron-friendly catalogs and reference service in both traditional face-to-face and newer virtual settings, recognized the importance of training staff as part of continuous improvement in customer service, and emphasized the power of using technology to improve delivery of library services. As trends and technologies have evolved, Lipow successfully articulated how those changes could be integrated into the traditional library organization. Her position regarding library issues, including the importance of the “human factor” in reference service, has helped us shape our patron-centered service philosophy. This has impacted the reference service we strive to provide, the issues we advocate for, and the environments in which we work

    Building skills F2F – Using chat reference techniques

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    The UTSA Library, like many organizations, has been experiencing a period of rapid growth and change. Even positive change can cause stress in departments, and one way to help employees deal with change, while still providing customer-oriented service, is to establish a regular forum for discussion that encourages departmental communication. Training is an important aspect of employee development; however, the literature indicates that, in many organizations, training is often given little attention and relegated to the sidelines due to other demands on staff. With the hiring of new personnel, including a new Head of Reference and a Training Coordinator, the UTSA Library’s weekly meetings model was expanded to include more systematic training, including special events such as summer workshops. UTSA librarians provided training in-house, worked with vendors, and collaborated with librarians at other institutions to provide a variety of training sessions to Reference staff. This paper illustrates the training process by providing an overview of training offered to the UTSA Library Reference staff. To compare their training program with those at other libraries, UTSA librarians surveyed other academic libraries in the San Antonio area to determine what types of ongoing training were incorporated into their Reference departments. This paper concludes with recommendations for the future of the UTSA Library’s Reference training program

    Predicting Listing Prices In Dynamic Short Term Rental Markets Using Machine Learning Models

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    Our research group wanted to take on the difficult task of predicting prices in a dynamic market. And short term rentals such as Airbnb listings seemed to be the perfect proving ground to do such a thing. Airbnb has revolutionized the travel industry by providing a platform for homeowners to rent out their properties to travelers. The pricing of Airbnb rentals is prone to high fluctuations, with prices changing frequently based on demand, seasonality, and other factors. Accurate prediction of Airbnb rental prices is crucial for hosts to optimize their revenue and for travelers to make informed booking decisions. In this project, we aim to predict the prices of Airbnb rentals using a machine learning modeling approach. Our project expands on earlier research in the area of analyzing Airbnb rental prices by taking a methodical machine learning approach as well as incorporating sentiment analysis into our feature engineering. We intend to gain a deeper understanding on periodic changes of Airbnb rental prices. The primary objective of this study is to construct an accurate machine learning model for predicting Airbnb rental prices specifically in Austin, Texas. Our project's secondary objective is to identify the key factors that drive Airbnb rental prices and to investigate how these factors vary across different locations and property types.Comment: 40 pages, 10 tables, 12 figure

    Faculty Recital:Kimberly McCoul Risinger, Flute David Chapman, Piano

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    Kemp Recital Hall Tuesday Evening January 26, 1999 8:00p

    Tricarboxylic acid cycle enzyme activities in a mouse model of methylmalonic aciduria

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    Methylmalonic acidemia (MMA) is a propionate pathway disorder caused by dysfunction of the mitochondrial enzyme methylmalonyl-CoA mutase (MMUT). MMUT catalyzes the conversion of methylmalonyl-CoA to succinyl-CoA, an anaplerotic reaction which feeds into the tricarboxylic acid (TCA) cycle. As part of the pathological mechanisms of MMA, previous studies have suggested there is decreased TCA activity due to a toxic inhibition of TCA cycle enzymes by MMA related metabolites, in addition to reduced anaplerosis. Here, we have utilized mitochondria isolated from livers of a mouse model of MMA (Mut-ko/ki) and their littermate controls (Ki/wt) to examine the amounts and enzyme functions of most of the TCA cycle enzymes. We have performed mRNA quantification, protein semi-quantitation, and enzyme activity quantification for TCA cycle enzymes in these samples. Expression profiling showed increased mRNA levels of fumarate hydratase in the Mut-ko/ki samples, which by contrast had reduced protein levels as detected by immunoblot, while all other mRNA levels were unaltered. Immunoblotting also revealed decreased protein levels of 2-oxoglutarate dehydrogenase and malate dehydrogenase 2. Interesting, the decreased protein amount of 2-oxoglutarate dehydrogenase was reflected in decreased activity for this enzyme while there is a trend towards decreased activity of fumarate hydratase and malate dehydrogenase 2. Citrate synthase, isocitrate dehydrogenase 2/3, succinyl-CoA synthase, and succinate dehydrogenase are not statistically different in terms of quantity of enzyme or activity. Finally, we found decreased activity when examining the function of methylmalonyl-CoA mutase in series with succinate synthase and succinate dehydrogenase in the Mut-ko/ki mice compared to their littermate controls, as expected. This study demonstrates decreased activity of certain TCA cycle enzymes and by corollary decreased TCA cycle function, but it supports decreased protein quantity rather than toxic inhibition as the underlying mechanism of action. SUMMARY: Methylmalonic acidemia (MMA) is an inborn metabolic disorder of propionate catabolism. In this disorder, toxic metabolites are considered to be the major pathogenic mechanism for acute and long-term complications. However, despite optimized therapies aimed at reducing metabolite levels, patients continue to suffer from late complications, including metabolic stroke and renal insufficiency. Since the propionate pathway feeds into the tricarboxylic acid (TCA) cycle, we investigated TCA cycle function in a constitutive MMA mouse model. We demonstrated decreased amounts of the TCA enzymes, Mdh2 and Ogdh as semi-quantified by immunoblot. Enzymatic activity of Ogdh is also decreased in the MMA mouse model compared to controls. Thus, when the enzyme amounts are decreased, we see the enzymatic activity also decreased to a similar extent for Ogdh. Further studies to elucidate the structural and/or functional links between the TCA cycle and propionate pathways might lead to new treatment approaches for MMA patients

    Goals and Social Comparisons Promote Walking Behavior

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    The effectiveness of a pedometer intervention was affected by manipulating the goals given to participants and by providing social comparison feedback about how participants’ performance compared with others. In study 1 (n = 148), university staff members received a low, medium, or high walking goal (10%, 50%, or 100% increase over baseline walking). Participants walked 1358 more steps per day (95% confidence interval [CI], 729, 1985), when receiving a high goal than when receiving a medium goal, but a medium goal did not increase walking relative to a low goal (554 more steps; 95% CI, –71,1179). In study 2 (n = 64), participants received individual feedback only or individual plus social comparison feedback. Participants walked 1120 more steps per day (95% CI, 538, 1703) when receiving social comparison feedback than when receiving only individual feedback. Goals and the performance of others act as reference points and influence the effect that pedometer feedback has on walking behavior, illustrating the applicability of the principles of behavioral economics and social psychology to the design of health behavior interventions

    An uncommon clinical presentation of relapsing dilated cardiomyopathy with identification of sequence variations in MYNPC3, KCNH2 and mitochondrial tRNA cysteine

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    We describe a young girl with dilated cardiomyopathy, long QT syndrome, and possible energy deficiency. Two major sequence changes were identified by whole exome sequencing (WES) and mitochondrial DNA analysis that were interpreted as potentially causative. Changes were identified in the KCNH2 gene and mitochondrial tRNA for cysteine. A variation was also seen in MYPBC3. Since the launch of WES as a clinically available technology in 2010, there has been concern regarding the identification of variants unrelated to the patient\u27s phenotype. However, in cases where targeted sequencing fails to explain the clinical presentation, the underlying etiology could be more complex than anticipated. In this situation, the extensive reach of this tool helped explain both her phenotype and family history

    Dietary Intake and Nitrogen Balance in British Army Infantry Recruits Undergoing Basic Training

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    We assessed dietary intake and nitrogen balance during 14 weeks of Basic Training (BT) in British Army Infantry recruits. Nineteen men (mean ± SD: age 19.9 ± 2.6 years, height: 175.7 ± 6.5 cm, body mass 80.3 ± 10.1 kg) at the Infantry Training Centre, Catterick (ITC(C)) volunteered. Nutrient intakes and 24-h urinary nitrogen balance were assessed in weeks 2, 6 and 11 of BT. Nutrient intake was assessed using researcher-led weighed food records and food diaries, and Nutritics professional dietary software. Data were compared between weeks using a repeated-measures analysis of variance (ANOVA) with statistical significance set at p ≀ 0.05. There was a significant difference in protein intake (g) between weeks 2 and 11 of BT (115 ± 18 vs. 91 ± 20 g, p = 0.02, ES = 1.26). There was no significant difference in mean absolute daily energy (p = 0.44), fat (p = 0.79) or carbohydrate (CHO) intake (p = 0.06) between weeks. Nitrogen balance was maintained in weeks 2, 6 and 11, but declined throughout BT (2: 4.6 ± 4.1 g, 6: 1.6 ± 4.5 g, 11: −0.2 ± 5.5 g, p = 0.07). A protein intake of 1.5 g·kg−1·d−1 may be sufficient in the early stages of BT, but higher intakes may be individually needed later on in BT

    Plasma fibroblast growth factor-21 levels in patients with inborn errors of metabolism

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    Fibroblast growth factor-21 (FGF21) levels are elevated in patients with primary mitochondrial disorders but have not been studied in patients with inborn errors of metabolism (IEM) known to have secondary mitochondrial dysfunction. We measured plasma FGF21 by ELISA in patients with and without IEM. FGF21 levels were higher in patients with IEM compared to without IEM (370 pg/dL vs. 0–65 pg/dL). Further study of FGF21 as a biomarker in IEM is warranted
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