67 research outputs found

    A New Leap Forward of Exercise Science - What Should We Do?

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    Continued Mat Pilates Exercise Improve Basal Physical Fitness, Core Stability and Back Pain in Healthy College Female

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    PURPOSE The purpose of this study was to investigate the effects of 8 weeks of mat Pilates exercise on back pain, muscle mass, isokinetic muscle function, and core stability in healthy college female. METHODS Twenty healthy college females (aged 21.7±2.5 years) were recruited for the study. The participants were divided into two groups: mat Pilates exercise group (MP, n=10) and non-Pilates control group (CON, n=10). The MP group participated in the mat Pilates exercise program for 60 minutes a day, 3 days per week for 8 weeks. Back pain and basal physical fitness were assessed before and after the experimental period. Left and right core stabilities at 0°, 45°, 90°, 135°, and 180° were measured using Centaur (BFMC, Germany). Isokinetic muscle function (60°/s) of both the knee and trunk was also measured using the isokinetic dynamometer Cybex. RESULTS After mat Pilates exercise for 8 weeks, there was a significant interaction between the MP and CON groups in back pain during daily activity and lower back stiffness (p<.05), respectively. There was also a significant interaction between the two groups in the left and right core stability at 45°, 90°, 135°, and 180° (p<.05, p<.01, p<.001), respectively. Additionally, there was a significant interaction between the two groups in the right knee and left knee isokinetic extensor muscle strength (p<.05, p<.001, respectively). However, there was no significant interaction between the two groups in trunk isokinetic extensor and flexor muscle strength (NS). There were no significant interactions between two groups in the muscle mass of total body, trunk, and legs (NS), respectively. Regarding basic physical fitness, there were significant interaction effects between the two groups in cardiovascular fitness, sagittal reach, and sit-ups (p<.05). CONCLUSIONS These results suggest that continued mat Pilates exercise can improve back pain and core stability with enhancement of leg isokinetic muscle strength independent of the muscle mass of the total body, trunk, and legs

    SNP Diagnosis in Elite Athletes by Korean Athletic Performance

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    PURPOSE The purpose of this study is to analyze SNPs related to performance (maximal strength vs. cardiovascular endurance) of world-class Korean elite athletes using the Genome-Wide Human SNP Array 6.0 and to determine genotypes related to maximal strength and cardiovascular endurance performance that are unique to “ Koreans”. METHODS Using the Genome-Wide Human SNP Array 6.0, we analyzed SNPs obtained from 54 world-class Korean elite athletes (Olympic participants/World Championship medalists). The group was divided into the 16 maximal strength group (12 males and 4 females weightlifters who had won medals at the Olympic and World Championships), 12 cardiovascular endurance group (12 males marathon runners who had run within 2 hours and 12 minutes in international competitions), and 26 individuals from the general population (25 males and 1 female). All the obtained SNPs were subjected to quality control (QC), and a total of 867,982 SNPs were analyzed between the marathon runners and general population subjects (641,040 SNPs) and between weightlifters and general population subjects (634,418 SNPs). RESULTS The number of SNPs with more than two SNPs within 100 kb, which satisfied the threshold of sample QC and significance level of p<.0001, was 60 in marathoners and 18 in weightlifters compared to the general population subjects. When the genomic features of SNPs of each performance trait were analyzed, the 60 SNPs for cardiovascular endurance with two or more SNPs within 100 kb that met the p<.0001 threshold for significance were distributed across 15 regions, and the 18 SNPs for maximal strength were distributed across 7 regions. CONCLUSIONS In conclusion, SNPs related to cardiovascular endurance and maximal strength suggest the possibility of producing gene chips to derive genotypes unique to “ Koreans” in the future. Additionally, this study provides important basic data for further research

    The Comparison of Physical Fitness Factors between Korea Water Polo National-team and Reserve-team Athletes

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    PURPOSE The purpose of the study was to evaluate isokinetic muscle strength (IMS), anaerobic power, basic physical fitness, and body composition of Korean water polo athletes in the national team (NT) and reserve team (RT). METHODS Twenty-nine male water polo athletes (aged 22.2±1.9 years) including 14 NT and 15 RT athletes participated in this study. The participants were evaluated for physiological parameters such as body composition, physical fitness, IMS, and anaerobic power. The IMS of the knees and shoulders (60°/s, 180°/s, and 240°/s, indicating maximal muscle strength, muscle power, and muscle endurance, respectively) and trunk (30°/s and 120°/s) were measured using a dynamometer (NORM, CSMI, USA). Anaerobic parameters were also measured using the 30-s maximal ergometer cycling Wingate test (Monark, Sweden). RESULTS No significant differences in the IMS of the knee were found between two groups. Although the IMSs of shoulder flexion at 180º/s and 60°/s were not significantly different between the two groups, the IMSs of shoulder extension at 180º/sec and 60°/s in NT athletes were higher than those in RT athletes (p<.05, p<.01). There were no significant differences between the NT and RT (NS) groups in the left and right knee flexion/extension ratios (H/Q ratio, 60º/sec, 180º/sec). However, a significant difference was found in the right shoulder extension/flexion ratio (E/F ratio) between the two groups. Although height, muscle mass, fat mass, and Wingate anaerobic power were not significantly different between the two groups, the FEV1 and FVC of NT athletes were higher than those of RT athletes, respectively (p<.05, p<.01). CONCLUSIONS These results suggest the athletic characteristics of water polo players who pass and shoot and make swimming movements. The difference in the shoulder extensor muscle strength was one of the determining factors for the performance of water polo athletes

    Study on an Agricultural Environment Monitoring Server System using Wireless Sensor Networks

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    This paper proposes an agricultural environment monitoring server system for monitoring information concerning an outdoors agricultural production environment utilizing Wireless Sensor Network (WSN) technology. The proposed agricultural environment monitoring server system collects environmental and soil information on the outdoors through WSN-based environmental and soil sensors, collects image information through CCTVs, and collects location information using GPS modules. This collected information is converted into a database through the agricultural environment monitoring server consisting of a sensor manager, which manages information collected from the WSN sensors, an image information manager, which manages image information collected from CCTVs, and a GPS manager, which processes location information of the agricultural environment monitoring server system, and provides it to producers. In addition, a solar cell-based power supply is implemented for the server system so that it could be used in agricultural environments with insufficient power infrastructure. This agricultural environment monitoring server system could even monitor the environmental information on the outdoors remotely, and it could be expected that the use of such a system could contribute to increasing crop yields and improving quality in the agricultural field by supporting the decision making of crop producers through analysis of the collected information

    Comparison of the chemical compositions and nutritive values of various pumpkin (Cucurbitaceae) species and parts

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    Pumpkins have considerable variation in nutrient contents depending on the cultivation environment, species, or part. In this study, the general chemical compositions and some bioactive components, such as tocopherols, carotenoids, and β-sitosterol, were analyzed in three major species of pumpkin (Cucurbitaceae pepo, C. moschata, and C. maxima) grown in Korea and also in three parts (peel, flesh, and seed) of each pumpkin species. C. maxima had significantly more carbohydrate, protein, fat, and fiber than C. pepo or C. moschata (P < 0.05). The moisture content as well as the amino acid and arginine contents in all parts of the pumpkin was highest in C. pepo. The major fatty acids in the seeds were palmitic, stearic, oleic, and linoleic acids. C. pepo and C. moschata seeds had significantly more γ-tocopherol than C. maxima, whose seeds had the highest β-carotene content. C. pepo seeds had significantly more β-sitosterol than the others. Nutrient compositions differed considerably among the pumpkin species and parts. These results will be useful in updating the nutrient compositions of pumpkin in the Korean food composition database. Additional analyses of various pumpkins grown in different years and in different areas of Korea are needed

    Involvement of Cox-2 in the metastatic potential of chemotherapy-resistant breast cancer cells

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    <p>Abstract</p> <p>Background</p> <p>A major problem with the use of current chemotherapy regimens for several cancers, including breast cancer, is development of intrinsic or acquired drug resistance, which results in disease recurrence and metastasis. However, the mechanisms underlying this drug resistance are unknown. To study the molecular mechanisms underlying the invasive and metastatic activities of drug-resistant cancer cells, we generated a doxorubicin-resistant MCF-7 breast cancer cell line (MCF-7/DOX).</p> <p>Methods</p> <p>We used MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assays, flow cytometry assays, DNA fragmentation assays, Western blot analysis, cell invasion assays, small interfering RNA (siRNA) transfection, reverse transcription-polymerase chain reaction, experimental lung metastasis models, and gelatin and fibrinogen/plasminogen zymography to study the molecular mechanism of metastatic activities in MCF-7/DOX cells.</p> <p>Results</p> <p>We found that MCF-7/DOX acquired invasive activities. In addition, Western blot analysis showed increased expression of epidermal growth factor receptor (EGFR) and Cox-2 in MCF-7/DOX cells. Inhibition of Cox-2, phosphoinositide 3-kinase (PI3K)/Akt, or mitogen-activated protein kinase (MAPK) pathways effectively inhibited the invasive activities of MCF-7/DOX cells. Gelatin and fibrinogen/plasminogen zymography analysis showed that the enzymatic activities of matrix metalloproteinase-2 (MMP-2), MMP-9, and urokinase-type plasminogen activator were markedly higher in MCF-7/DOX cells than in the MCF-7 cells. <it>In vitro </it>invasion assays and mouse models of lung metastasis demonstrated that MCF-7/DOX cells acquired invasive abilities. Using siRNAs and agonists specific for prostaglandin E (EP) receptors, we found that EP1 and EP3 played important roles in the invasiveness of MCF-7/DOX cells.</p> <p>Conclusions</p> <p>We found that the invasive activity of MCF-7/DOX cells is mediated by Cox-2, which is induced by the EGFR-activated PI3K/Akt and MAPK pathways. In addition, EP1 and EP3 are important in the Cox-2-induced invasion of MCF-7/DOX cells. Therefore, not only Cox-2 but also EP1 and EP3 could be important targets for chemosensitization and inhibition of metastasis in breast cancers that are resistant to chemotherapy.</p
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