"Debt, Price Flexibility and Aggregate Stability"

In conventional macroeconomic thought, price flexibility stabilizes thc economy. The more quickly prices fall (or inflation decreases) in a demand-induced recession, the faster output returns to its full-employment level. An alternative tradition, however, suggests that price flexibility can be destabilizing. If a recession reduces expectations of Jitlzre prices, this can raise current real interest rates and dampen aggregate demand. In addition, as actual current prices fall in a recession, real debt burdens rise which can reduce aggregate demand due to financial distress or the response of capital markets. This paper presents simulations from a dynamic macroeconomic model designed to examine the empirical effects of price flexibility. Our results show that, for credible specifications and parameter values7 the destabilizing effects of greater price flexibility can be larger than the conventional stabilizing channels. Therefore, it is possible that greater price flexibility magnifies the severity of economic contractions initiated by negative demand shocks.

The Need for Large-Scale, Longitudinal Empirical Studies in Middle Level Education Research

This essay describes and discusses the ongoing need for large-scale, longitudinal, empirical research studies focused on middle grades education. After a statement of the problem and concerns, the essay describes several prior middle grades efforts and research studies. Recommendations for future research efforts to inform policy decisions are provided, including roles for the Middle Level Education Research Special Interest Group (MLER SIG) of the American Educational Research Association (AERA) and other national organizations

Fundamentals for Student Success in the Middle Grades

Determining how to provide the best education possible for young adolescents begins with the answers to three essential questions: Who are young adolescents? What do we know about them, their abilities, interests and strengths? Based on what we know about young adolescents, what should schools do to provide a quality education for each and every student? And finally, is there evidence that these recommended practices improve student achievement? How do we know programs and practices designed specifically with young adolescents in mind make a difference? To answer these questions, we will first outline some of the developmental characteristics of young adolescents and look at the implications for teaching and learning. We will then look at national recommendations for schools based on what we know about young adolescents. Finally, we will consider some of the research that supports these recommendations

An Experimental Analysis Of the Demand For Payday Loans

The payday loan industry is one of the fastest growing segments of the consumer financial services market in the United States. We design an environment similar to the one that payday loan customers face and then conduct a laboratory experiment to examine what effect, if any, the existence of payday loans has on individuals\u27 abilities to manage and to survive financial setbacks. Our primary objective is to examine whether access to payday loans improves or worsens the likelihood of financial survival in our experiment. We also test the degree to which people\u27s use of payday loans affects their ability to survive financially. We find that payday loans help the subjects to absorb expenditure shocks and therefore survive financially. However, subjects whose demand for payday loans exceeds a certain threshold level are at a greater risk than a corresponding subject in the treatment in which payday loans do not exist

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge

There is tremendous potential for genome sequencing to improve clinical diagnosis and care once it becomes routinely accessible, but this will require formalizing research methods into clinical best practices in the areas of sequence data generation, analysis, interpretation and reporting. The CLARITY Challenge was designed to spur convergence in methods for diagnosing genetic disease starting from clinical case history and genome sequencing data. DNA samples were obtained from three families with heritable genetic disorders and genomic sequence data were donated by sequencing platform vendors. The challenge was to analyze and interpret these data with the goals of identifying disease-causing variants and reporting the findings in a clinically useful format. Participating contestant groups were solicited broadly, and an independent panel of judges evaluated their performance. RESULTS: A total of 30 international groups were engaged. The entries reveal a general convergence of practices on most elements of the analysis and interpretation process. However, even given this commonality of approach, only two groups identified the consensus candidate variants in all disease cases, demonstrating a need for consistent fine-tuning of the generally accepted methods. There was greater diversity of the final clinical report content and in the patient consenting process, demonstrating that these areas require additional exploration and standardization. CONCLUSIONS: The CLARITY Challenge provides a comprehensive assessment of current practices for using genome sequencing to diagnose and report genetic diseases. There is remarkable convergence in bioinformatic techniques, but medical interpretation and reporting are areas that require further development by many groups

International AIDS Society global scientific strategy: towards an HIV cure 2016

Antiretroviral therapy is not curative. Given the challenges in providing lifelong therapy to a global population of more than 35 million people living with HIV, there is intense interest in developing a cure for HIV infection. The International AIDS Society convened a group of international experts to develop a scientific strategy for research towards an HIV cure. This Perspective summarizes the group's strategy

Common Planning Time

The article focuses on common planning time. According to a definition by Kellough and Kellough, common planning time is a regularly scheduled time during the school day when teachers who teach the same students meet for joint planning, parent conferences, materials preparation and student evaluation. It notes that student achievements are typically high in schools with high levels of common planning time. It claims that most district schools in the U.S. perceive common planning time as a privilege but due to challenging financial times, it is said to be one component to be eradicated from school budgets. It notes a study presented in the article that showed the positive effects of common planning time on teaching, learning and achievement of young adolescents