Geomorphological and geochemical characterization of the 11 August 2008 mud volcano eruption at S. Barbara village (Sicily, Italy) and its possible relationship with seismic activity

On 11 August 2008 a paroxysmal eruption occurred at Santa Barbara mud volcano (MV), located close to Caltanissetta, one of the most densely populated cities of Sicily (Italy). An associated minor event took place on August 2009. Both the events caused severe damage to civil infrastructures located within a range of about 2 km from the eruptive vent. Geomorphological, geochemical, and seismological investigations were carried out for framing the events in the appropriate geodynamic context. Geomorphological surveys recognized, in the immediate surrounding of the main emission point, two different families of processes and landforms: (i) ground deformations and (ii) changes in morphology and number of the fluid emitting vents. These processes were associated to a wider network of fractures, seemingly generated by the shock wave produced by the gas blast that occurred at the main paroxysm. Geochemical characterization allowed an estimation of the source of the fluids, or at least their last standing, at about 3 km depth. Finally, the close time relationships observed between anomalous increments of seismic activity and the two main paroxysmal events accounted for a possible common trigger for both the phenomena, even with different timing due to the very different initial conditions and characteristics of the two processes, i.e. seismogenesis and gas overloading

Central extensions, classical non-equivariant maps and residual symmetries

The arising of central extensions is discussed in two contexts. At first classical counterparts of quantum anomalies (deserving being named as "classical anomalies") are associated with a peculiar subclass of the non-equivariant maps. Further, the notion of "residual symmetry" for theories formulated in given non-vanishing EM backgrounds is introduced. It is pointed out that this is a Lie-algebraic, model-independent, concept.Comment: 8 pages, LaTex. Talk given at the International Conference "Renormalization Group and Anomalies in Gravitation and Cosmology", Ouro Preto, Brazil, March 2003. To appear in the Proceeding

The use of non-invasive field techniques in the study of small topographically closed lakes: two case studies in Sicily (Italy)

Small endhoreic (topografically closed) lakes represent a little percentage of continental waters but, in arid or sub-arid regions, they develop special ecosystems potentially prone to ecological involution due to climatic changes. The mandatory use of light, non-invasive field techniques is often required, especially in protected areas. In the present work the use of non-invasive techniques like GPS−based bathymetric and photographic surveys have been applied to the study of two lakes, Specchio di Venere and Sfondato (Sicily, southern Italy), both natural reserves. The comparison between historical surveys and modern GPS−based bathymetries highlighted the difficulty of using the former for the reconstruction of climatic-induced variations due to the low number of measurements (spatial aliasing). In particular, at the intracaldera Lake Specchio di Venere, a high resolution survey gave new insights into a peculiar geo-ecosystem whose evolution is driven by both volcanic phenomena and biomineralization processes. On the contrary, the morphology of Lake Sfondato floor is much more simple and driven only by the superimposition of a detrital sedimentation on the initial collapse that generated the lake. The comparison betweem direct measurements and estimated changes of lake level, carried out between February 2008 and October 2009 variations, allowed us to test different hypotheses of hydrological balances, leading to opposite conclusions with respect to previous studies and remarking the fundamental importance of direct measurements in the validation of theoretical hydrological models

Geomorphological and geochemical characterization of the August 11, 2008 mud volcano eruption at S. Barbara village (Sicily, Italy) and its possible relationship with seismic activity

On August 11, 2008 a paroxysmal eruption occurred at Santa Barbara mud volcano (MV), located close to Caltanissetta, one of the most densely populated cities of Sicily (Italy). An associated minor event took place on August, 2009. Both the events caused severe damages to civil infrastructures located within a range of about 2 km from the eruptive vent. Geomorphological, geochemical and seismological investigations were carried out for framing the events in the appropriate geodynamic context. Geomorphological surveys recognized, in the immediate surrounding of the main emission point, two different families of processes and landforms: ground deformations and changes in morphology and number of the fluid emitting vents. These processes were associated to a wider network of fractures, seemingly generated by the shock wave produced by the gas blast occurred at the main paroxysm. Geochemical characterization allowed to estimate the source of the fluids, or at least their last standing, at about 3 km depth. Finally, the close time relationships observed between anomalous increments of seismic activity and the two main paroxysmal events, accounted for a common possible trigger for both the phenomena, even if with a different timing due to the very different initial conditions and characteristics of the two processes, i.e. seismogenesis and gas overloading

Non Abelian BF theories with sources and 2-D gravity

We study the interaction of non-Abelian topological $BF$ theories defined on two dimensional manifolds with point sources carrying non-Abelian charges. We identify the most general solution for the field equations on simply and multiply connected two-manifolds. Taking the particular choice of the so-called extended Poincar\'e group as the gauge group we discuss how recent discussions of two dimensional gravity models do fit in this formalism.Comment: 20 pages, Latex, To appear in Phys Rev D5

Scattering of Plane Waves in Self-Dual Yang-Mills Theory

We consider the classical self-dual Yang-Mills equation in 3+1-dimensional Minkowski space. We have found an exact solution, which describes scattering of $n$ plane waves. In order to write the solution in a compact form, it is convenient to introduce a scattering operator $\hat{T}$. It acts in the direct product of three linear spaces: 1) universal enveloping of $su(N)$ Lie algebra, 2) $n$-dimensional vector space and 3) space of functions defined on the unit interval.Comment: 16 pages, LaTeX fil

Platelet isoprostane overproduction in diabetic patients treated with aspirin

Aspirin modestly influences cardiovascular events in patients with type 2 diabetes mellitus (T2DM), but the reason is unclear. The aim of the study was to determine whether in T2DM patients aspirin enhances platelet isoprostanes, which are eicosanoids with proaggregating properties derived from arachidonic acid oxidation by platelet NOX2, the catalytic subunit of reduced NAD phosphate oxidase. A cross-sectional study was performed comparing T2DM patients, treated (n = 50) or not treated (n = 50) with 100 mg/day aspirin, with 100 nondiabetic patients, matched for age, sex, atherosclerosis risk factors, and aspirin treatment. A short-term (7 days) treatment with 100 mg/day aspirin also was performed in 36 aspirin-free diabetic and nondiabetic patients. Higher platelet recruitment, platelet isoprostane, and NOX2 activation was found in diabetic versus nondiabetic patients and in aspirin-treated diabetic patients versus nontreated patients (P < 0.001). Platelet thromboxane (Tx) A(2) (P < 0.001) was inhibited in all aspirin-treated patients. In the interventional study, aspirin similarly inhibited platelet TxA(2) in diabetic and nondiabetic patients (P < 0.001). Platelet recruitment, isoprostane levels, and NOX2 activation showed a parallel increase in diabetic patients (P < 0.001) and no changes in nondiabetic patients. These findings suggest that in aspirin-treated diabetic patients, oxidative stress-mediated platelet isoprostane overproduction is associated with enhanced platelet recruitment, an effect that mitigates aspirin-mediated TxA(2) inhibition

EGFR CELL EXPRESSION IN BLADDER WASHINGS AS A RISK MARKER TOOL IN NON MUSCLE-INVASIVE BLADDER CANCER. PRELIMINARY EXPERIENCE

INTRODUCTION AND OBJECTIVES: Up to day, EGFR expression has been determined mainly in tissue specimens of muscleinvasive bladder cancer and its overexpression has been associated with worse prognosis and shorter survival. Urothelial EGFR status after NMIBC transurethral resection (TUR) could indicate the risk of recurrence and progression. We investigated the feasibility of EGFR measurement in bladder washings of patients undergoing intravesical adjuvant therapy for NMIBC and its usefulness in identifying risk subgroups. METHODS: Our prospective study included patients after TUR of NMIBC and healthy controls. A cellular pellet was obtained from bladder washing, and RNA extraction performed by miRNeasy Mini Kit (Qiagen). Good quality of RNA was checked. The cDNA obtained from RNA was used to perform a gene expression analysis by a Real Time PCR, according to the method of the comparative quantification (DDCt) with an endogenous control (Cyclophilin). Every reaction was set in triplicate as a guarantee of quality. Patients were grouped for EAU risk class and maintained in follow-up. The EGFR expressions were statistically analyzed according to EAU risk groups and to patients0 outcome. EGFR gene expression values were expressed in FOLDs of change compared to healthy controls (EGFR¼1). RESULTS: Fifty-eight patients and 21 healthy age-matched controls were entered. An adequate cellular pellet was obtained in 50 patients (86.2%) showing a median EGFR expression of 2.0 folds (IQR 0.6-4.3, p¼0.0004). After TUR and adjuvant intravesical therapy, 22 (55%) out of 40 high-risk patients, showed EGFR decrease to 1.3 folds (IQR 0.9-1.5), while 18 (45%) showed elevated EGFR, median 4.7 (IQR 4.1-11.6). At 25 months median follow-up (IQR 19.0-34.8), 20 (40%) patients recurred and 6 (12%) progressed. Among patients with or without EGFR gene increase, 9 (22.5%) and 5 (12.5%) recurred and 5 (12.5%) and 1 (2.5%) progressed, respectively. CONCLUSIONS: In our experience EGFR expression measurement was feasible in more than 85% of patients and resulted related to EAU risk classes for recurrence and progression, showing different behavior during intravesical therapy. It was possible to identify a subgroup of high risk patients overexpressing EGFR in spite of intravesical adjuvant therapy. EGFR evaluation in bladder washing could represent a repeatable and useful tool to identify a subgroup of patients at risk for progression unresponsive to intravesical adjuvant therapy and candidate to early radical cystectom

Speech Prosody as a Bridge Between Psychopathology and Linguistics: The Case of the Schizophrenia Spectrum

Patients with schizophrenia spectrum disorders experience severe difficulties in interpersonal communication, as described by traditional psychopathology and current research on social cognition. From a linguistic perspective, pragmatic abilities are crucial for successful communication. Empirical studies have shown that these abilities are significantly impaired in this group of patients. Prosody, the tone of voice with which words and sentences are pronounced, is one of the most important carriers of pragmatic meaning and can serve a range of functions from linguistic to emotional ones. Most of the existing literature on prosody of patients with schizophrenia spectrum disorders focuses on the expression of emotion, generally showing significant impairments. By contrast, the use of non-emotional prosody in these patients is scarcely investigated. In this paper, we first present a linguistic model to classify prosodic functions. Second, we discuss existing studies on the use of non-emotional prosody in these patients, providing an overview of the state of the art. Third, we delineate possible future lines of research in this field, also taking into account some classical psychopathological assumptions, for both diagnostic and therapeutic purposes

A solution to the zero-hamiltonian problem in 2-D gravity

The zero-hamiltonian problem, present in reparametrization invariant systems, is solved for the 2-D induced gravity model. Working with methods developed by Henneaux et al. we find systematically the reduced phase-space physics, generated by an {\it effective} hamiltonian obtained after complete gauge fixing.Comment: 5 pages, revte